Works by Zweckstetter, Markus

Results: 180

Myelin Membrane Assembly Is Driven by a Phase Transition of Myelin Basic Proteins Into a Cohesive Protein Meshwork.

Published in:

PLoS Biology, 2013, v. 11, n. 6, p. 1, doi. 10.1371/journal.pbio.1001577

By:

Aggarwal, Shweta;
Snaidero, Nicolas;
Pähler, Gesa;
Frey, Steffen;
Sánchez, Paula;
Zweckstetter, Markus;
Janshoff, Andreas;
Schneider, Anja;
Weil, Marie-Theres;
Schaap, Iwan A. T.;
Görlich, Dirk;
Simons, Mikael

Publication type:

Article

Structural Polymorphism of 441-Residue Tau at Single Residue Resolution.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000034, doi. 10.1371/journal.pbio.1000034

By:

Mukrasch, Marco D.;
Bibow, Stefan;
Korukottu, Jegannath;
Jeganathan, Sadasivam;
Biernat, Jacek;
Griesinger, Christian;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

Fast Motions Dominate Dynamics of Intrinsically Disordered Tau Protein at High Temperatures.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 17, p. 1, doi. 10.1002/chem.202203493

By:

Abyzov, Anton;
Mandelkow, Eckhard;
Zweckstetter, Markus;
Rezaei‐Ghaleh, Nasrollah

Publication type:

Article

Vorhersage der Rotationskorrelationszeit in dynamischen Mehrdomänenproteinen und supramolekularen Komplexen.

Published in:

Angewandte Chemie, 2013, v. 125, n. 43, p. 11621, doi. 10.1002/ange.201305094

By:

Rezaei ‐ Ghaleh, Nasrollah;
Klama, Frederik;
Munari, Francesca;
Zweckstetter, Markus

Publication type:

Article

Mechanismus der Phenothiazin-induzierten Hemmung der Tau-Aggregation.

Published in:

Angewandte Chemie, 2013, v. 125, n. 12, p. 3596, doi. 10.1002/ange.201208290

By:

Akoury, Elias;
Pickhardt, Marcus;
Gajda, Michal;
Biernat, Jacek;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

N-H-Spinkopplungen: Einblicke in Proteinwasserstoffbrücken.

Published in:

Angewandte Chemie, 2013, v. 125, n. 12, p. 3610, doi. 10.1002/ange.201209641

By:

Xiang, Sheng ‐ Qi;
Narayanan, Raghavendran L.;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Is Enantiomer Assignment Possible by NMR Spectroscopy Using Residual Dipolar Couplings from Chiral Nonracemic Alignment Media?-A Critical Assessment.

Published in:

Angewandte Chemie, 2012, v. 124, n. 33, p. 8512, doi. 10.1002/ange.201107626

By:

Berger, Robert;
Courtieu, Jacques;
Gil, Roberto R.;
Griesinger, Christian;
Köck, Matthias;
Lesot, Philippe;
Luy, Burkhard;
Merlet, Denis;
Navarro-Vázquez, Armando;
Reggelin, Michael;
Reinscheid, Uwe M.;
Thiele, Christina M.;
Zweckstetter, Markus

Publication type:

Article

Die dynamische Struktur von Tau-Filamenten.

Published in:

Angewandte Chemie, 2011, v. 123, n. 48, p. 11723, doi. 10.1002/ange.201105493

By:

Bibow, Stefan;
Mukrasch, Marco D.;
Chinnathambi, Subashchandrabose;
Biernat, Jacek;
Griesinger, Christian;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

Die native Konformation des N-Terminus des humanen spannungsabhängigen Anionenkanals VDAC1.

Published in:

Angewandte Chemie, 2010, v. 122, n. 10, p. 1926, doi. 10.1002/ange.200906241

By:

Schneider, Robert;
Etzkorn, Manuel;
Giller, Karin;
Daebel, Venita;
Eisfeld, Jörg;
Zweckstetter, Markus;
Griesinger, Christian;
Becker, Stefan;
Lange, Adam

Publication type:

Article

Ladungsinduzierte molekulare Ausrichtung von intrinsisch ungeordneten ProteinenL.S. erhält ein Marie-Curie-Stipendium (MEST-CT-2004-504193), M.-K.C. ein Stipendium des DFG-Graduiertenkollegs und M.Z. ein Emmy Noether-Stipendium (ZW 71/1-5)....

Published in:

Angewandte Chemie, 2006, v. 118, n. 42, p. 7173, doi. 10.1002/ange.200602317

By:

Lukasz Skora;
Min-Kyu Cho;
Hai-Young Kim;
Stefan Becker;
Claudio O. Fernandez;
Martin Blackledge;
Markus Zweckstetter

Publication type:

Article

Using temperature coefficients to support resonance assignment of intrinsically disordered proteins.

Published in:

Journal of Biomolecular NMR, 2025, v. 79, n. 1, p. 59, doi. 10.1007/s10858-024-00452-9

By:

Putko, Paulina;
Romero, Javier Agustin;
Pantoja, Christian F.;
Zweckstetter, Markus;
Kazimierczuk, Krzysztof;
Zawadzka-Kazimierczuk, Anna

Publication type:

Article

Improved validation of IDP ensembles by one-bond Cα-Hα scalar couplings.

Published in:

Journal of Biomolecular NMR, 2015, v. 63, n. 3, p. 299, doi. 10.1007/s10858-015-9990-z

By:

Gapsys, Vytautas;
Narayanan, Raghavendran;
Xiang, ShengQi;
Groot, Bert;
Zweckstetter, Markus

Publication type:

Article

Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2.

Published in:

Journal of Biomolecular NMR, 2015, v. 61, n. 3/4, p. 311, doi. 10.1007/s10858-014-9876-5

By:

Gattin, Zrinka;
Schneider, Robert;
Laukat, Yvonne;
Giller, Karin;
Maier, Elke;
Zweckstetter, Markus;
Griesinger, Christian;
Benz, Roland;
Becker, Stefan;
Lange, Adam

Publication type:

Article

A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins.

Published in:

Journal of Biomolecular NMR, 2014, v. 60, n. 4, p. 231, doi. 10.1007/s10858-014-9872-9

By:

Yao, Xuejun;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy.

Published in:

Journal of Biomolecular NMR, 2011, v. 49, n. 2, p. 111, doi. 10.1007/s10858-011-9471-y

By:

Gruene, Tim;
Cho, Min-Kyu;
Karyagina, Irina;
Kim, Hai-Young;
Grosse, Christian;
Giller, Karin;
Zweckstetter, Markus;
Becker, Stefan

Publication type:

Article

High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment.

Published in:

Journal of Biomolecular NMR, 2008, v. 40, n. 1, p. 1, doi. 10.1007/s10858-007-9204-4

By:

Rumpel, Sigrun;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

1H, 15N, and 13C Resonance Assignment of the C2A Domain of Rabphilin3A.

Published in:

Journal of Biomolecular NMR, 2006, v. 36, p. 20, doi. 10.1007/s10858-005-6051-z

By:

Montaville, Pierre;
Kim, Hai-Young;
Vijayan, Vinesh;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Letter to the Editor: Backbone resonance assignment of the homodimeric, 35 kDa chaperone CesT from enteropathogenicEscherichia coli.

Published in:

Journal of Biomolecular NMR, 2005, v. 31, n. 4, p. 377, doi. 10.1007/s10858-005-1607-5

By:

Rumpel, Sigrun;
Kim, Hai-Young;
Vijayan, Vinesh;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Mars – robust automatic backbone assignment of proteins.

Published in:

Journal of Biomolecular NMR, 2004, v. 30, n. 1, p. 11, doi. 10.1023/B:JNMR.0000042954.99056.ad

By:

Young-Sang Jung;
Zweckstetter, Markus

Publication type:

Article

Backbone assignment of proteins with known structure using residual dipolar couplings.

Published in:

Journal of Biomolecular NMR, 2004, v. 30, n. 1, p. 25, doi. 10.1023/B:JNMR.0000042955.14647.77

By:

Young-Sang Jung;
Zweckstetter, Markus

Publication type:

Article

Determination of molecular alignment tensors without backbone resonance assignment: Aid to rapid analysis of protein-protein interactions.

Published in:

Journal of Biomolecular NMR, 2003, v. 27, n. 1, p. 41, doi. 10.1023/A:1024768328860

By:

Zweckstetter, Markus

Publication type:

Article

Evaluation of uncertainty in alignment tensors obtained from dipolar couplings.

Published in:

Journal of Biomolecular NMR, 2002, v. 23, n. 2, p. 127, doi. 10.1023/A:1016316415261

By:

Zweckstetter, Markus;
Bax, Ad

Publication type:

Article

Characterization of molecular alignment in aqueous suspensions of Pf1 bacteriophage.

Published in:

Journal of Biomolecular NMR, 2001, v. 20, n. 4, p. 365, doi. 10.1023/A:1011263920003

By:

Zweckstetter, Markus;
Bax, Ad

Publication type:

Article

Amyloidogenic potential of α-chymotrypsin in different conformational states.

Published in:

Biopolymers, 2009, v. 91, n. 1, p. 28, doi. 10.1002/bip.21079

By:

Rezaei-Ghaleh, Nasrollah;
Zweckstetter, Markus;
Morshedi, Dina;
Ebrahim-Habibi, Azadeh;
Nemat-Gorgani, Mohsen

Publication type:

Article

Fasudil attenuates aggregation of a-synuclein in models of Parkinson's disease.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0310-y

By:

Tatenhorst, Lars;
Eckermann, Katrin;
Dambeck, Vivian;
Fonseca-Ornelas, Luis;
Walle, Hagen;
da Fonseca, Tomás Lopes;
Koch, Jan C.;
Becker, Stefan;
Tönges, Lars;
Bähr, Mathias;
Outeiro, Tiago F.;
Zweckstetter, Markus;
Lingor, Paul

Publication type:

Article

Internalization routes of cell-penetrating melanoma antigen peptides into human dendritic cells.

Published in:

Experimental Dermatology, 2014, v. 23, n. 1, p. 20, doi. 10.1111/exd.12285

By:

Buhl, Timo;
Braun, Andrea;
Forkel, Susann;
Möbius, Wiebke;
Werven, Lars;
Jahn, Olaf;
Rezaei‐Ghaleh, Nasrollah;
Zweckstetter, Markus;
Mempel, Martin;
Schön, Michael P.;
Haenssle, Holger A.

Publication type:

Article

Alternative low-populated conformations prompt phase transitions in polyalanine repeat expansions.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46236-5

By:

Antón, Rosa;
Treviño, Miguel Á.;
Pantoja-Uceda, David;
Félix, Sara;
Babu, María;
Cabrita, Eurico J.;
Zweckstetter, Markus;
Tinnefeld, Philip;
Vera, Andrés M.;
Oroz, Javier

Publication type:

Article

Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41633-8

By:

Flores-Solis, David;
Lushpinskaia, Irina P.;
Polyansky, Anton A.;
Changiarath, Arya;
Boehning, Marc;
Mirkovic, Milana;
Walshe, James;
Pietrek, Lisa M.;
Cramer, Patrick;
Stelzl, Lukas S.;
Zagrovic, Bojan;
Zweckstetter, Markus

Publication type:

Article

Methylene blue accelerates liquid-to-gel transition of tau condensates impacting tau function and pathology.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41241-6

By:

Huang, Yongqi;
Wen, Jitao;
Ramirez, Lisa-Marie;
Gümüşdil, Eymen;
Pokhrel, Pravin;
Man, Viet H.;
Ye, Haiqiong;
Han, Yue;
Liu, Yunfei;
Li, Ping;
Su, Zhengding;
Wang, Junmei;
Mao, Hanbin;
Zweckstetter, Markus;
Perrett, Sarah;
Wu, Si;
Gao, Meng

Publication type:

Article

Determining the Physico‐Chemical Composition of Biomolecular Condensates from Spatially‐Resolved NMR.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 17, p. 1, doi. 10.1002/anie.202218078

By:

Pantoja, Christian F.;
Ibáñez de Opakua, Alain;
Cima‐Omori, Maria‐Sol;
Zweckstetter, Markus

Publication type:

Article

Disease‐Associated Tau Phosphorylation Hinders Tubulin Assembly within Tau Condensates.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 2, p. 726, doi. 10.1002/anie.202011157

By:

Savastano, Adriana;
Flores, David;
Kadavath, Harindranath;
Biernat, Jacek;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

Determination of Complex Small‐Molecule Structures Using Molecular Alignment Simulation.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 15, p. 6172, doi. 10.1002/anie.202000311

By:

Ibáñez de Opakua, Alain;
Klama, Frederik;
Ndukwe, Ikenna E.;
Martin, Gary E.;
Williamson, R. Thomas;
Zweckstetter, Markus

Publication type:

Article

The Molecular Basis of the Interaction of Cyclophilin A with α‐Synuclein.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 14, p. 5643, doi. 10.1002/anie.201914878

By:

Favretto, Filippo;
Baker, Jeremy D.;
Strohäker, Timo;
Andreas, Loren B.;
Blair, Laura J.;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Conformational diversity of human HP1α.

Published in:

Protein Science: A Publication of the Protein Society, 2024, v. 33, n. 7, p. 1, doi. 10.1002/pro.5079

By:

Ukmar‐Godec, Tina;
Yu, Taekyung;
de Opakua, Alain Ibanez;
Pantoja, Christian F.;
Munari, Francesca;
Zweckstetter, Markus

Publication type:

Article

Parkinson's disease‐linked V15A mutation facilitates α‐synuclein aggregation by reducing membrane affinity.

Published in:

Protein Science: A Publication of the Protein Society, 2023, v. 32, n. 8, p. 1, doi. 10.1002/pro.4693

By:

Buratti, Fiamma A.;
Fernández, Claudio Oscar;
Zweckstetter, Markus

Publication type:

Article

Contributions of the N‐terminal intrinsically disordered region of the severe acute respiratory syndrome coronavirus 2 nucleocapsid protein to RNA‐induced phase separation.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 9, p. 1, doi. 10.1002/pro.4409

By:

Zachrdla, Milan;
Savastano, Adriana;
Ibáñez de Opakua, Alain;
Cima‐Omori, Maria‐Sol;
Zweckstetter, Markus

Publication type:

Article

Aromaticity at position 39 in α‐synuclein: A modulator of amyloid fibril assembly and membrane‐bound conformations.

Published in:

Protein Science: A Publication of the Protein Society, 2022, v. 31, n. 7, p. 1, doi. 10.1002/pro.4360

By:

Buratti, Fiamma A.;
Boeffinger, Nicola;
Garro, Hugo A.;
Flores, Jesica S.;
Hita, Francisco J.;
Gonçalves, Phelippe do Carmo;
Copello, Federico dos Reis;
Lizarraga, Leonardo;
Rossetti, Giulia;
Carloni, Paolo;
Zweckstetter, Markus;
Outeiro, Tiago F.;
Eimer, Stefan;
Griesinger, Christian;
Fernández, Claudio O.

Publication type:

Article

Introduction: Biophysics of biomolecular condensates.

Published in:

Protein Science: A Publication of the Protein Society, 2021, v. 30, n. 7, p. 1274, doi. 10.1002/pro.4135

By:

Zweckstetter, Markus

Publication type:

Article

Interplay between tau and α‐synuclein liquid–liquid phase separation.

Published in:

Protein Science: A Publication of the Protein Society, 2021, v. 30, n. 7, p. 1326, doi. 10.1002/pro.4025

By:

Siegert, Anna;
Rankovic, Marija;
Favretto, Filippo;
Ukmar‐Godec, Tina;
Strohäker, Timo;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Liquid–liquid phase separation of tau: From molecular biophysics to physiology and disease.

Published in:

Protein Science: A Publication of the Protein Society, 2021, v. 30, n. 7, p. 1294, doi. 10.1002/pro.4093

By:

Rai, Sandeep K.;
Savastano, Adriana;
Singh, Priyanka;
Mukhopadhyay, Samrat;
Zweckstetter, Markus

Publication type:

Article

Molecular basis of the interaction of Hsp90 with its co‐chaperone Hop.

Published in:

Protein Science: A Publication of the Protein Society, 2020, v. 29, n. 12, p. 2422, doi. 10.1002/pro.3969

By:

Lott, Antonia;
Oroz, Javier;
Zweckstetter, Markus

Publication type:

Article

Dynamic Aha1 co‐chaperone binding to human Hsp90.

Published in:

Protein Science: A Publication of the Protein Society, 2019, v. 28, n. 9, p. 1545, doi. 10.1002/pro.3678

By:

Oroz, Javier;
Blair, Laura J.;
Zweckstetter, Markus

Publication type:

Article

Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain.

Published in:

Brain Pathology, 2023, v. 33, n. 5, p. 1, doi. 10.1111/bpa.13196

By:

Zhang, Shuyu;
Dauer, Karina;
Strohäker, Timo;
Tatenhorst, Lars;
Caldi Gomes, Lucas;
Mayer, Simon;
Jung, Byung Chul;
Kim, Woojin S.;
Lee, Seung‐Jae;
Becker, Stefan;
Liesche‐Starnecker, Friederike;
Zweckstetter, Markus;
Lingor, Paul

Publication type:

Article

β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.

Published in:

2013

By:

Taschenberger, Grit;
Toloe, Johan;
Tereshchenko, Julia;
Akerboom, Jasper;
Wales, Pauline;
Benz, Roland;
Becker, Stefan;
Outeiro, Tiago F;
Looger, Loren L;
Bähr, Mathias;
Zweckstetter, Markus;
Kügler, Sebastian

Publication type:

journal article

β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.

Published in:

Annals of Neurology, 2013, v. 74, n. 1, p. 109, doi. 10.1002/ana.23905

By:

Taschenberger, Grit;
Toloe, Johan;
Tereshchenko, Julia;
Akerboom, Jasper;
Wales, Pauline;
Benz, Roland;
Becker, Stefan;
Outeiro, Tiago F.;
Looger, Loren L.;
Bähr, Mathias;
Zweckstetter, Markus;
Kügler, Sebastian

Publication type:

Article

Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease.

Published in:

EMBO Journal, 2011, v. 30, n. 11, p. 2255, doi. 10.1038/emboj.2011.138

By:

Kumar, Sathish;
Rezaei-Ghaleh, Nasrollah;
Terwel, Dick;
Thal, Dietmar R;
Richard, Mélisande;
Hoch, Michael;
Mc Donald, Jessica M;
Wüllner, Ullrich;
Glebov, Konstantin;
Heneka, Michael T;
Walsh, Dominic M;
Zweckstetter, Markus;
Walter, Jochen

Publication type:

Article

Mitogen-activated protein kinases interacting kinases are autoinhibited by a reprogrammed activation segment.

Published in:

EMBO Journal, 2006, v. 25, n. 17, p. 4020, doi. 10.1038/sj.emboj.7601285

By:

Jauch, Ralf;
Cho, Min-Kyu;
Jäkel, Stefan;
Netter, Catharina;
Schreiter, Kay;
Aicher, Babette;
Zweckstetter, Markus;
Jäckle, Herbert;
Wahl, Markus C.

Publication type:

Article

Structure and DNA-binding properties of the cytolysin regulator CylR2 from Enterococcus faecalis.

Published in:

EMBO Journal, 2004, v. 23, n. 18, p. 3632, doi. 10.1038/sj.emboj.7600367

By:

Rumpel, Sigrun;
Razeto, Adelia;
Pillar, Chris M.;
Vijayan, Vinesh;
Taylor, Austin;
Giller, Karin;
Gilmore, Michael S.;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

NMR of a-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

Published in:

EMBO Journal, 2004, v. 23, n. 10, p. 2039, doi. 10.1038/sj.emboj.7600211

By:

Fernández, Claudio O.;
Hoyer, Wolfgang;
Zweckstetter, Markus;
Jares-Erijman, Elizabeth A.;
Subramaniam, Vinod;
Griesinger, Christian;
Jovin, Thomas M.

Publication type:

Article

Site-Specific Effect of Amyloid B-Peptide (Aβ) Phosphorylation on Its Conformation and Aggregation

Published in:

2011

By:

Kumar, Sathish;
Rezaei-Ghaleh, Nasrollah;
Zweckstetter, Markus;
Terwel, Dick;
Thal, Dietmar;
Heneka, Michael;
Walter, Jochen

Publication type:

Abstract