Works matching AU Zweckstetter, Markus

Results: 181

Molecular Mechanisms Mediating the Transfer of Disease-Associated Proteins and Effects on Neuronal Activity.

Published in:

Journal of Parkinson's Disease, 2022, v. 12, n. 8, p. 2397, doi. 10.3233/JPD-223516

By:

Brás, Inês C.;
Khani, Mohammad H.;
Vasili, Eftychia;
Möbius, Wiebke;
Riedel, Dietmar;
Parfentev, Iwan;
Gerhardt, Ellen;
Fahlbusch, Christiane;
Urlaub, Henning;
Zweckstetter, Markus;
Gollisch, Tim;
Outeiro, Tiago F.

Publication type:

Article

Cooperative structure of the heterotrimeric pre-mRNA retention and splicing complex.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 10, p. 911, doi. 10.1038/nsmb.2889

By:

Wysoczański, Piotr;
Schneider, Cornelius;
Xiang, ShengQi;
Munari, Francesca;
Trowitzsch, Simon;
Wahl, Markus C;
Lührmann, Reinhard;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Fast Motions Dominate Dynamics of Intrinsically Disordered Tau Protein at High Temperatures.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 17, p. 1, doi. 10.1002/chem.202203493

By:

Abyzov, Anton;
Mandelkow, Eckhard;
Zweckstetter, Markus;
Rezaei‐Ghaleh, Nasrollah

Publication type:

Article

Hochauflösende NMR-spektroskopische Bestimmung der dynamischen Struktur von Membranproteinen.

Published in:

Angewandte Chemie, 2016, v. 128, n. 35, p. 10674, doi. 10.1002/ange.201602639

By:

Jaremko, Mariusz;
Jaremko, Łukasz;
Villinger, Saskia;
Schmidt, Christian D.;
Griesinger, Christian;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Faltungszustand des Proteins Tau bei Bindung an Mikrotubuli.

Published in:

Angewandte Chemie, 2015, v. 127, n. 35, p. 10488, doi. 10.1002/ange.201501714

By:

Kadavath, Harindranath;
Jaremko, Mariusz;
Jaremko, Łukasz;
Biernat, Jacek;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

Paramagnetische Effekte mittels eines markierten Reporterproteins.

Published in:

Angewandte Chemie, 2015, v. 127, n. 1, p. 343, doi. 10.1002/ange.201408615

By:

Camacho ‐ Zarco, Aldo R.;
Munari, Francesca;
Wegstroth, Melanie;
Liu, Wei ‐ Min;
Ubbink, Marcellus;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Vorhersage der Rotationskorrelationszeit in dynamischen Mehrdomänenproteinen und supramolekularen Komplexen.

Published in:

Angewandte Chemie, 2013, v. 125, n. 43, p. 11621, doi. 10.1002/ange.201305094

By:

Rezaei ‐ Ghaleh, Nasrollah;
Klama, Frederik;
Munari, Francesca;
Zweckstetter, Markus

Publication type:

Article

Mechanismus der Phenothiazin-induzierten Hemmung der Tau-Aggregation.

Published in:

Angewandte Chemie, 2013, v. 125, n. 12, p. 3596, doi. 10.1002/ange.201208290

By:

Akoury, Elias;
Pickhardt, Marcus;
Gajda, Michal;
Biernat, Jacek;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

N-H-Spinkopplungen: Einblicke in Proteinwasserstoffbrücken.

Published in:

Angewandte Chemie, 2013, v. 125, n. 12, p. 3610, doi. 10.1002/ange.201209641

By:

Xiang, Sheng ‐ Qi;
Narayanan, Raghavendran L.;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Is Enantiomer Assignment Possible by NMR Spectroscopy Using Residual Dipolar Couplings from Chiral Nonracemic Alignment Media?-A Critical Assessment.

Published in:

Angewandte Chemie, 2012, v. 124, n. 33, p. 8512, doi. 10.1002/ange.201107626

By:

Berger, Robert;
Courtieu, Jacques;
Gil, Roberto R.;
Griesinger, Christian;
Köck, Matthias;
Lesot, Philippe;
Luy, Burkhard;
Merlet, Denis;
Navarro-Vázquez, Armando;
Reggelin, Michael;
Reinscheid, Uwe M.;
Thiele, Christina M.;
Zweckstetter, Markus

Publication type:

Article

Die dynamische Struktur von Tau-Filamenten.

Published in:

Angewandte Chemie, 2011, v. 123, n. 48, p. 11723, doi. 10.1002/ange.201105493

By:

Bibow, Stefan;
Mukrasch, Marco D.;
Chinnathambi, Subashchandrabose;
Biernat, Jacek;
Griesinger, Christian;
Mandelkow, Eckhard;
Zweckstetter, Markus

Publication type:

Article

Amyloidogenic potential of α-chymotrypsin in different conformational states.

Published in:

Biopolymers, 2009, v. 91, n. 1, p. 28, doi. 10.1002/bip.21079

By:

Rezaei-Ghaleh, Nasrollah;
Zweckstetter, Markus;
Morshedi, Dina;
Ebrahim-Habibi, Azadeh;
Nemat-Gorgani, Mohsen

Publication type:

Article

HYCUD: a computational tool for prediction of effective rotational correlation time in flexible proteins.

Published in:

Bioinformatics, 2015, v. 31, n. 8, p. 1319, doi. 10.1093/bioinformatics/btu824

By:

Rezaei-Ghaleh, Nasrollah;
Klama, Frederik;
Munari, Francesca;
Zweckstetter, Markus

Publication type:

Article

HYCUD: a computational tool for prediction of effective rotational correlation time in flexible proteins.

Published in:

2015

By:

Rezaei-Ghaleh, Nasrollah;
Klama, Frederik;
Munari, Francesca;
Zweckstetter, Markus

Publication type:

Product Review

Extending the applicability of P3D for structure determination of small molecules.

Published in:

Magnetic Resonance, 2021, v. 2, n. 1, p. 105, doi. 10.5194/mr-2-105-2021

By:

Ibáñez de Opakua, Alain;
Zweckstetter, Markus

Publication type:

Article

The Native Conformation of the Human VDAC1 N Terminus.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 10, p. 1882, doi. 10.1002/anie.200906241

By:

Schneider, Robert;
Etzkorn, Manuel;
Giller, Karin;
Daebel, Venita;
Eisfeld, Jörg;
Zweckstetter, Markus;
Griesinger, Christian;
Becker, Stefan;
Lange, Adam

Publication type:

Article

Dissociation of Amyloid Fibrils of α-Synuclein in Supercooled Water.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 27, p. 5046, doi. 10.1002/anie.200800342

By:

Kim, Hai-Young;
Cho, Min-Kyu;
Riedel, Dietmar;
Fernandez, Claudio O.;
Zweckstetter, Markus

Publication type:

Article

Cover Picture: Dissociation of Amyloid Fibrils of α-Synuclein in Supercooled Water (Angew. Chem. Int. Ed. 27/2008).

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 27, p. 4939, doi. 10.1002/anie.200890127

By:

Kim, Hai-Young;
Cho, Min-Kyu;
Riedel, Dietmar;
Fernandez, Claudio O.;
Zweckstetter, Markus

Publication type:

Article

Fast High-Resolution Protein Structure Determination by Using Unassigned NMR Data.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 7, p. 1176, doi. 10.1002/anie.200603213

By:

Korukottu, Jegannath;
Bayrhuber, Monika;
Montaville, Pierre;
Vijayan, Vinesh;
Jung, Young-Sang;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Charge-Induced Molecular Alignment of Intrinsically Disordered Proteins.

Published in:

Angewandte Chemie International Edition, 2006, v. 45, n. 42, p. 7012, doi. 10.1002/anie.200602317

By:

Skora, Lukasz;
Cho, Min-Kyu;
Kim, Hai-Young;
Becker, Stefan;
Fernandez, Claudio O.;
Blackledge, Martin;
Zweckstetter, Markus

Publication type:

Article

Simultaneous Assignment and Structure Determination of Protein Backbones by Using NMR Dipolar CouplingsWe thank Gaetano Montelione for the peak lists of the Z domain and Christian Griesinger for useful discussions. M.Z. is the recipient of a DFG Emmy Noether-Fellowship (ZW 71/1-3).

Published in:

Angewandte Chemie International Edition, 2004, v. 43, n. 26, p. 3479, doi. 10.1002/anie.200353588

By:

Young-Sang Jung;
Mukesh Sharma;
Markus Zweckstetter

Publication type:

Article

Backbone and side-chain resonance assignment of the A147T polymorph of mouse TSPO in complex with a high-affinity radioligand.

Published in:

Biomolecular NMR Assignments, 2016, v. 10, n. 1, p. 79, doi. 10.1007/s12104-015-9642-y

By:

Jaremko, Mariusz;
Jaremko, Łukasz;
Giller, Karin;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Alpha‐synuclein fibrils amplified from multiple system atrophy and Parkinson's disease patient brain spread after intracerebral injection into mouse brain.

Published in:

Brain Pathology, 2023, v. 33, n. 5, p. 1, doi. 10.1111/bpa.13196

By:

Zhang, Shuyu;
Dauer, Karina;
Strohäker, Timo;
Tatenhorst, Lars;
Caldi Gomes, Lucas;
Mayer, Simon;
Jung, Byung Chul;
Kim, Woojin S.;
Lee, Seung‐Jae;
Becker, Stefan;
Liesche‐Starnecker, Friederike;
Zweckstetter, Markus;
Lingor, Paul

Publication type:

Article

Insights into Cholesterol/Membrane Protein Interactions Using Paramagnetic Solid‐State NMR.

Published in:

Chemistry - A European Journal, 2018, v. 24, n. 66, p. 17606, doi. 10.1002/chem.201804550

By:

Jaipuria, Garima;
Zweckstetter, Markus;
Giller, Karin;
Leonov, Andrei;
Becker, Stefan

Publication type:

Article

Small-Molecule-Induced Soluble Oligomers of α-Synuclein with Helical Structure.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 53, p. 13010, doi. 10.1002/chem.201703001

By:

Fonseca‐Ornelas, Luis;
Schmidt, Carla;
Camacho‐Zarco, Aldo R.;
Fernandez, Claudio O.;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ<sub>−3- x</sub>-Peptides.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 25, p. 8685, doi. 10.1002/chem.201600892

By:

Beyer, Isaak;
Rezaei ‐ Ghaleh, Nasrollah;
Klafki, Hans ‐ Wolfgang;
Jahn, Olaf;
Haußmann, Ute;
Wiltfang, Jens;
Zweckstetter, Markus;
Knölker, Hans ‐ Joachim

Publication type:

Article

Conformational Flexibility in the Transmembrane Protein TSPO.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 46, p. 16555, doi. 10.1002/chem.201502314

By:

Jaremko, Łukasz;
Jaremko, Mariusz;
Giller, Karin;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits.

Published in:

Acta Neuropathologica, 2013, v. 126, n. 2, p. 189, doi. 10.1007/s00401-013-1129-2

By:

Bouter, Yvonne;
Dietrich, Katharina;
Wittnam, Jessica;
Rezaei-Ghaleh, Nasrollah;
Pillot, Thierry;
Papot-Couturier, Sophie;
Lefebvre, Thomas;
Sprenger, Frederick;
Wirths, Oliver;
Zweckstetter, Markus;
Bayer, Thomas

Publication type:

Article

Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.

Published in:

Acta Neuropathologica, 2013, v. 125, n. 6, p. 795, doi. 10.1007/s00401-013-1114-9

By:

Wagner, Jens;
Ryazanov, Sergey;
Leonov, Andrei;
Levin, Johannes;
Shi, Song;
Schmidt, Felix;
Prix, Catharina;
Pan-Montojo, Francisco;
Bertsch, Uwe;
Mitteregger-Kretzschmar, Gerda;
Geissen, Markus;
Eiden, Martin;
Leidel, Fabienne;
Hirschberger, Thomas;
Deeg, Andreas;
Krauth, Julian;
Zinth, Wolfgang;
Tavan, Paul;
Pilger, Jens;
Zweckstetter, Markus

Publication type:

Article

Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons.

Published in:

Acta Neuropathologica, 2012, v. 123, n. 5, p. 671, doi. 10.1007/s00401-011-0926-8

By:

Taschenberger, Grit;
Garrido, Manuel;
Tereshchenko, Yuliya;
Bähr, Mathias;
Zweckstetter, Markus;
Kügler, Sebastian

Publication type:

Article

Sumoylation inhibits α-synuclein aggregation and toxicity.

Published in:

Journal of Cell Biology, 2011, v. 194, n. 1, p. 49, doi. 10.1083/jcb.201010117

By:

Krumova, Petranka;
Meulmeester, Erik;
Garrido, Manuel;
Tirard, Marilyn;
He-Hsuan Hsiao;
Bossis, Guillaume;
Urlaub, Henning;
Zweckstetter, Markus;
Kügler, Sebastian;
Melchior, Frauke;
Bähr, Mathias;
Weishaupt, Jochen H.

Publication type:

Article

Sumoylation inhibits α-synuclein aggregation and toxicity.

Published in:

Journal of Cell Biology, 2011, v. 193, n. 8, p. 49, doi. 10.1083/jcb.201010117

By:

Krumova, Petranka;
Meulmeester, Erik;
Garrido, Manuel;
Tirard, Marilyn;
He-Hsuan Hsiao;
Bossis, Guillaume;
Urlaub, Henning;
Zweckstetter, Markus;
Kügler, Sebastian;
Melchior, Frauke;
Bähr, Mathias;
Weishaupt, Jochen H.

Publication type:

Article

Special issue: Multicomponent lipid membranes—how molecular organisation leads to function.

Published in:

2021

By:

de Groot, Bert;
Janshoff, Andreas;
Steinem, Claudia;
Zweckstetter, Markus

Publication type:

Editorial

Structure, gating and interactions of the voltage-dependent anion channel.

Published in:

European Biophysics Journal, 2021, v. 50, n. 2, p. 159, doi. 10.1007/s00249-021-01515-7

By:

Najbauer, Eszter E.;
Becker, Stefan;
Giller, Karin;
Zweckstetter, Markus;
Lange, Adam;
Steinem, Claudia;
de Groot, Bert L.;
Griesinger, Christian;
Andreas, Loren B.

Publication type:

Article

Membrane-embedded TSPO: an NMR view.

Published in:

European Biophysics Journal, 2021, v. 50, n. 2, p. 173, doi. 10.1007/s00249-020-01487-0

By:

Rivière, Gwladys;
Jaipuria, Garima;
Andreas, Loren B.;
Leonov, Andrei;
Giller, Karin;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Hsp multichaperone complex buffers pathologically modified Tau.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31396-z

By:

Moll, Antonia;
Ramirez, Lisa Marie;
Ninov, Momchil;
Schwarz, Juliane;
Urlaub, Henning;
Zweckstetter, Markus

Publication type:

Article

Co-factor-free aggregation of tau into seeding-competent RNA-sequestering amyloid fibrils.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24362-8

By:

Chakraborty, Pijush;
Rivière, Gwladys;
Liu, Shu;
de Opakua, Alain Ibáñez;
Dervişoğlu, Rıza;
Hebestreit, Alina;
Andreas, Loren B.;
Vorberg, Ina M.;
Zweckstetter, Markus

Publication type:

Article

NMR-Based Detection of Hydrogen/Deuterium Exchange in Liposome-Embedded Membrane Proteins.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0112374

By:

Yao, Xuejun;
Dürr, Ulrich H. N.;
Gattin, Zrinka;
Laukat, Yvonne;
Narayanan, Rhagavendran L.;
Brückner, Ann-Kathrin;
Meisinger, Chris;
Lange, Adam;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Structural Plasticity in Human Heterochromatin Protein 1β.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060887

By:

Munari, Francesca;
Rezaei-Ghaleh, Nasrollah;
Xiang, Shengqi;
Fischle, Wolfgang;
Zweckstetter, Markus

Publication type:

Article

Characterization of Molecular Determinants of the Conformational Stability of Macrophage Migration Inhibitory Factor: Leucine 46 Hydrophobic Pocket.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0045024

By:

El-Turk, Farah;
Fauvet, Bruno;
Ashrafi, Amer;
Ouertatani-Sakouhi, Hajer;
Min-Kyu Cho;
Neri, Marilisa;
Cascella, Michele;
Rothlisberger, Ursula;
Pojer, Florence;
Zweckstetter, Markus;
Lashuel, Hilal;
Vertessy, Beata G.

Publication type:

Article

Cold-induced changes in the protein ubiquitin.

Published in:

PLoS ONE, 2012, v. 7, n. 6, p. 1, doi. 10.1371/journal.pone.0037270

By:

Min-Kyu Cho;
ShengQi Xiang;
Hai-Young Kim;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Pre-Fibrillar α-Synuclein Mutants Cause Parkinson's Disease-Like Non-Motor Symptoms in Drosophila.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024701

By:

Gajula Balija, Madhu Babu;
Griesinger, Christian;
Herzig, Alf;
Zweckstetter, Markus;
Jäckle, Herbert

Publication type:

Article

Interaction between Amyloid Beta Peptide and an Aggregation Blocker Peptide Mimicking Islet Amyloid Polypeptide.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020289

By:

Rezaei-Ghaleh, Nasrollah;
Andreetto, Erika;
Yan, Li-Mei;
Kapurniotu, Aphrodite;
Zweckstetter, Markus

Publication type:

Article

High-Resolution 3D Structure Determination of Kaliotoxin by Solid-State NMR Spectroscopy.

Published in:

PLoS ONE, 2008, v. 3, n. 6, p. 1, doi. 10.1371/journal.pone.0002359

By:

Korukottu, Jegannath;
Schneider, Robert;
Vijayan, Vinesh;
Lange, Adam;
Pongs, Olaf;
Becker, Stefan;
Baldus, Marc;
Zweckstetter, Markus

Publication type:

Article

Imbalance of Hsp70 family variants fosters tau accumulation.

Published in:

FASEB Journal, 2013, v. 27, n. 4, p. 1450, doi. 10.1096/fj.12-220889

By:

Jinwal, Umesh K.;
Akoury, Elias;
Abisambra, Jose F.;
O'Leary III, John C.;
Thompson, Andrea D.;
Blair, Laura J.;
Ying Jin;
Bacon, Justin;
Nordhues, Bryce A.;
Cockman, Matthew;
Zhang, Juan;
Pengfei Li;
Bo Zhang;
Borysov, Sergiy;
Uversky, Vladimir N.;
Biernat, Jacek;
Mandelkow, Eckhard;
Gestwicki, Jason E.;
Zweckstetter, Markus;
Dickey, Chad A.

Publication type:

Article

Improved validation of IDP ensembles by one-bond Cα-Hα scalar couplings.

Published in:

Journal of Biomolecular NMR, 2015, v. 63, n. 3, p. 299, doi. 10.1007/s10858-015-9990-z

By:

Gapsys, Vytautas;
Narayanan, Raghavendran;
Xiang, ShengQi;
Groot, Bert;
Zweckstetter, Markus

Publication type:

Article

Solid-state NMR, electrophysiology and molecular dynamics characterization of human VDAC2.

Published in:

Journal of Biomolecular NMR, 2015, v. 61, n. 3/4, p. 311, doi. 10.1007/s10858-014-9876-5

By:

Gattin, Zrinka;
Schneider, Robert;
Laukat, Yvonne;
Giller, Karin;
Maier, Elke;
Zweckstetter, Markus;
Griesinger, Christian;
Benz, Roland;
Becker, Stefan;
Lange, Adam

Publication type:

Article

A six-dimensional alpha proton detection-based APSY experiment for backbone assignment of intrinsically disordered proteins.

Published in:

Journal of Biomolecular NMR, 2014, v. 60, n. 4, p. 231, doi. 10.1007/s10858-014-9872-9

By:

Yao, Xuejun;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article

Integrated analysis of the conformation of a protein-linked spin label by crystallography, EPR and NMR spectroscopy.

Published in:

Journal of Biomolecular NMR, 2011, v. 49, n. 2, p. 111, doi. 10.1007/s10858-011-9471-y

By:

Gruene, Tim;
Cho, Min-Kyu;
Karyagina, Irina;
Kim, Hai-Young;
Grosse, Christian;
Giller, Karin;
Zweckstetter, Markus;
Becker, Stefan

Publication type:

Article

High-resolution structure determination of the CylR2 homodimer using paramagnetic relaxation enhancement and structure-based prediction of molecular alignment.

Published in:

Journal of Biomolecular NMR, 2008, v. 40, n. 1, p. 1, doi. 10.1007/s10858-007-9204-4

By:

Rumpel, Sigrun;
Becker, Stefan;
Zweckstetter, Markus

Publication type:

Article