Works by Zwarthoff, Ellen C

Results: 44

PD-L1 expression in high-risk non-muscle invasive bladder cancer is not a biomarker of response to BCG.

Published in:

World Journal of Urology, 2025, v. 43, n. 1, p. 1, doi. 10.1007/s00345-024-05392-5

By:

de Jong, Florus C.;
Kvikstad, Vebjørn;
Hoedemaeker, Robert F.;
van der Made, Angelique C. J.;
van der Bosch, Thierry P.;
van Casteren, Niels J.;
van Kessel, Kim E. M.;
Zwarthoff, Ellen C.;
Boormans, Joost L.;
Zuiverloon, Tahlita C. M.

Publication type:

Article

Cationic amphiphilic drugs as potential anticancer therapy for bladder cancer.

Published in:

Molecular Oncology, 2020, v. 14, n. 12, p. 3121, doi. 10.1002/1878-0261.12793

By:

Horst, Geertje;
Merbel, Arjanneke F.;
Ruigrok, Eline;
Mark, Maaike H.;
Ploeg, Emily;
Appelman, Laura;
Tvingsholm, Siri;
Jäätelä, Marja;
Uhm, Janneke;
Kruithof‐de Julio, Marianna;
Thalmann, George N.;
Pelger, Rob C. M.;
Bangma, Chris H.;
Boormans, Joost L.;
Pluijm, Gabri;
Zwarthoff, Ellen C.

Publication type:

Article

HRAS mutations in bladder cancer at an early age and the possible association with the Costello Syndrome.

Published in:

European Journal of Human Genetics, 2014, v. 22, n. 6, p. 837, doi. 10.1038/ejhg.2013.251

By:

Beukers, Willemien;
Hercegovac, Aleksander;
Zwarthoff, Ellen C

Publication type:

Article

Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders.

Published in:

European Journal of Human Genetics, 2002, v. 10, n. 12, p. 819, doi. 10.1038/sj.ejhg.5200883

By:

van Rhijn, Bas W G;
van Tilborg, Angela A G;
Lurkin, Irene;
Bonaventure, Jacky;
de Vries, Annie;
Thiery, Jean-Paul;
van der Kwast, Theodorus H;
Zwarthoff, Ellen C;
Radvanyi, Francois

Publication type:

Article

A SNaPshot assay for the rapid and simple detection of four common hotspot codon mutations in the P1K3CA gene.

Published in:

BMC Research Notes, 2009, v. 2, p. 1, doi. 10.1186/1756-0500-2-66

By:

Hurst, Carolyn D.;
Zuiverloon, Tahlita C. M.;
Hafner, Christian;
Zwarthoff, Ellen C.;
Knowles, Margaret A.

Publication type:

Article

In-depth investigation of the molecular pathogenesis of bladder cancer in a unique 26-year old patient with extensive multifocal disease: a case report.

Published in:

2010

By:

Zuiverloon, Tahlita C. M.;
Abas, Cheno S.;
Van der Keur, Kirstin A.;
Vermeij, Marcel;
Tjin, Stephen S.;
Van Tilborg, Angela G.;
Busstra, Martijn;
Zwarthoff, Ellen C.

Publication type:

Case Study

Mosaicism of activating FGFR3 mutations in human skin causes epidermal nevi.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 8, p. 2201, doi. 10.1172/JCI28163

By:

Hafner, Christian;
van Oers, Johanna M. M.;
Vogt, Thomas;
Landthaler, Michael;
Stoehr, Robert;
Blaszyk, Hagen;
Hofstaedter, Ferdinand;
Zwarthoff, Ellen C.;
Hartmann, Arndt

Publication type:

Article

Prediction of Multiple Recurrent Events: A Comparison of Extended Cox Models in Bladder Cancer.

Published in:

American Journal of Epidemiology, 2017, v. 186, n. 5, p. 612, doi. 10.1093/aje/kwx133

By:

Smedinga, Hilde;
Steyerberg, Ewout W.;
Beukers, Willemien;
van Klaveren, David;
Zwarthoff, Ellen C.;
Vergouwe, Yvonne

Publication type:

Article

A G→A transition creates a branch point sequence and activation of a cryptic exon, resulting in the hereditary disorder neurofibromatosis 2.

Published in:

Human Molecular Genetics, 1998, v. 7, n. 3, p. 393, doi. 10.1093/hmg/7.3.393

By:

De Klein, Annelies;
Riegman, Peter H.J.;
Bijlsma, Emilia K.;
Heldoorn, Anneliek;
Muijtjens, Manja;
den Bakker, Michael A.;
Avezaat, Cees J.J.;
Zwarthoff, Ellen C.

Publication type:

Article

Loss of heterozygosity on chromosome 9 and loss of chromosome 9 copy number are separate events in the pathogenesis of transitional cell carcinoma of the bladder.

Published in:

International Journal of Cancer, 1998, v. 75, n. 1, p. 9, doi. 10.1002/(SICI)1097-0215(19980105)75:1<9::AID-IJC2>3.0.CO;2-1

By:

Van Tilborg, Angela A. G.;
Hekman, Arnold C. P.;
Vissers, Kees J.;
van der Kwast, Theo H.;
Zwarthoff, Ellen C.

Publication type:

Article

Modulation of intraepithelial expansion of human T24 bladder-carcinoma cells in murine urothelium by growth factors and extracellular-matrix components.

Published in:

International Journal of Cancer, 1995, v. 60, n. 5, p. 707, doi. 10.1002/ijc.2910600523

By:

Rebel, Johanna M. J.;
Thijssen, Cornelia D. E. M.;
Vermey, Marcel;
Zwarthoff, Ellen C.;
Van Der Kwast, Theodorus H.

Publication type:

Article

An in vitro model of intra-epithelial expansion of transformed urothelial cells.

Published in:

International Journal of Cancer, 1993, v. 54, n. 5, p. 846, doi. 10.1002/ijc.2910540520

By:

Rebel, Johanna M. J.;
De Boer, Willem I.;
Thijssen, Cornelia D. E. M.;
Vermey, Marcel;
Zwarthoff, Ellen C.;
Van Der Kwast, Theo H.

Publication type:

Article

A reported 20-gene expression signature to predict lymph node-positive disease at radical cystectomy for muscle-invasive bladder cancer is clinically not applicable.

Published in:

PLoS ONE, 2017, v. 12, n. 3, p. 1, doi. 10.1371/journal.pone.0174039

By:

van Kessel, Kim E. M.;
van de Werken, Harmen J. G.;
Lurkin, Irene;
Ziel – van der Made, Angelique C. J.;
Zwarthoff, Ellen C.;
Boormans, Joost L.

Publication type:

Article

No evidence of FGFR3 mutations in prostate cancer.

Published in:

Prostate, 2011, v. 71, n. 6, p. 637, doi. 10.1002/pros.21279

By:

Zuiverloon, Tahlita C.M.;
Boormans, Joost L.;
Trapman, Jan;
van Leenders, Geert J.L.H.;
Zwarthoff, Ellen C.

Publication type:

Article

Prognostic value of molecular markers, sub-stage and European Organisation for the Research and Treatment of Cancer risk scores in primary T1 bladder cancer.

Published in:

BJU International, 2012, v. 110, n. 8, p. 1169, doi. 10.1111/j.1464-410X.2012.10996.x

By:

van Rhijn, Bas W.G.;
Liu, Liyang;
Vis, André N.;
Bostrom, Peter J.;
Zuiverloon, Tahlita C.M.;
Fleshner, Neil E.;
van der Aa, Madelon N.M.;
Alkhateeb, Sultan S.;
Bangma, Chris H.;
Jewett, Michael A.S.;
Zwarthoff, Ellen C.;
Bapat, Bharati;
van der Kwast, Theo H.;
Zlotta, Alexandre R.

Publication type:

Article

A methylation assay for the detection of non-muscle-invasive bladder cancer (NMIBC) recurrences in voided urine.

Published in:

BJU International, 2012, v. 109, n. 6, p. 941, doi. 10.1111/j.1464-410X.2011.10428.x

By:

Zuiverloon, Tahlita C.M.;
Beukers, Willemien;
van der Keur, Kirstin A.;
Munoz, Jesrael R.;
Bangma, Chris H.;
Lingsma, Hester F.;
Eijkemans, Marinus J.C.;
Schouten, Jan P.;
Zwarthoff, Ellen C.

Publication type:

Article

Non-muscle-invasive bladder cancer surveillance for which cystoscopy is partly replaced by microsatellite analysis of urine: a cost-effective alternative?

Published in:

BJU International, 2009, v. 104, n. 1, p. 41, doi. 10.1111/j.1464-410X.2008.08323.x

By:

de Bekker-Grob, Esther W.;
van der Aa, Madelon N. M.;
Zwarthoff, Ellen C.;
Eijkemans, Marinus J. C.;
van Rhijn, Bas W.;
van der Kwast, Theo H.;
Steyerberg, Ewout W.

Publication type:

Article

Sexual function of patients under surveillance for bladder cancer.

Published in:

BJU International, 2009, v. 104, n. 1, p. 35, doi. 10.1111/j.1464-410X.2008.08333.x

By:

van der Aa, Madelon N. M.;
Bekker, Milou D.;
van der Kwast, Theo H.;
Essink-Bot, Marie-Louise;
Steyerberg, Ewout W.;
Zwarthoff, Ellen C.;
Sen, Fatma E. F.;
Elzevier, Henk W.

Publication type:

Article

Patients’ perceived burden of cystoscopic and urinary surveillance of bladder cancer: a randomized comparison.

Published in:

BJU International, 2008, v. 101, n. 9, p. 1106, doi. 10.1111/j.1464-410X.2007.07224.x

By:

van der Aa, Madelon N.M.;
Steyerberg, Ewout W.;
Sen, E. Fatma;
Zwarthoff, Ellen C.;
Kirkels, Wim J.;
van der Kwast, Theo H.;
Essink-Bot, Marie-Louise

Publication type:

Article

Chromosome 9 deletions are more frequent than FGFR3 mutations in flat urothelial hyperplasias of the bladder.

Published in:

International Journal of Cancer, 2006, v. 119, n. 5, p. 1212, doi. 10.1002/ijc.21958

By:

van Oers, Johanna M.M.;
Adam, Christoph;
Denzinger, Stefan;
Stoehr, Robert;
Bertz, Simone;
Zaak, Dirk;
Stief, Christian;
Hofstaedter, Ferdinand;
Zwarthoff, Ellen C.;
van der Kwast, Theodorus H.;
Knuechel, Ruth;
Hartmann, Arndt

Publication type:

Article

The Absence of BRAF, FGFR3, and PIK3CA Mutations Differentiates Lentigo Simplex from Melanocytic Nevus and Solar Lentigo.

Published in:

Journal of Investigative Dermatology, 2009, v. 129, n. 11, p. 2730, doi. 10.1038/jid.2009.146

By:

Hafner, Christian;
Stoehr, Robert;
van Oers, Johanna M. M.;
Zwarthoff, Ellen C.;
Hofstaedter, Ferdinand;
Klein, Christoph;
Landthaler, Michael;
Hartmann, Arndt;
Vogt, Thomas

Publication type:

Article

High Frequency of FGFR3 Mutations in Adenoid Seborrheic Keratoses.

Published in:

Journal of Investigative Dermatology, 2006, v. 126, n. 11, p. 2404, doi. 10.1038/sj.jid.5700422

By:

Hafner, Christian;
van Oers, Johanna M. M.;
Hartmann, Arndt;
Landthaler, Michael;
Stoehr, Robert;
Blaszyk, Hagen;
Hofstaedter, Ferdinand;
Zwarthoff, Ellen C.;
Vogt, Thomas

Publication type:

Article

Constitutional DNA-level aberrations in chromosome 22 in a patient with multiple meningiomas.

Published in:

Genes, Chromosomes & Cancer, 1994, v. 9, n. 2, p. 124, doi. 10.1002/gcc.2870090208

By:

Deprez, Ronald H. Lekanne;
Groen, Nicole A.;
Louz, Derrick;
Van Der Kwast, Theo H.;
Zwarthoff, Ellen C.;
Hagemeijer, Anne;
Van Drunen, Ellen;
Bootsma, Dirk;
Koper, Jan W.;
Avezaat, Cees J. J.

Publication type:

Article

A noninvasive multi-analyte diagnostic assay: combining protein and DNA markers to stratify bladder cancer patients.

Published in:

Research & Reports in Urology, 2012, n. 4, p. 17, doi. 10.2147/RRU.S28959

By:

Fernandez, Cecilia A.;
Millholland, John M.;
Zwarthoff, Ellen C.;
Feldman, Adam S.;
Karnes, R. Jeffrey;
Shuber, Anthony P.

Publication type:

Article

Long non-coding RNAs identify a subset of luminal muscle-invasive bladder cancer patients with favorable prognosis.

Published in:

Genome Medicine, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13073-019-0669-z

By:

de Jong, Joep J.;
Liu, Yang;
Robertson, A. Gordon;
Seiler, Roland;
Groeneveld, Clarice S.;
van der Heijden, Michiel S.;
Wright, Jonathan L.;
Douglas, James;
Dall'Era, Marc;
Crabb, Simon J.;
van Rhijn, Bas W. G.;
van Kessel, Kim E. M.;
Davicioni, Elai;
Castro, Mauro A. A.;
Lotan, Yair;
Zwarthoff, Ellen C.;
Black, Peter C.;
Boormans, Joost L.;
Gibb, Ewan A.

Publication type:

Article

Positive fibroblast growth factor receptor 3 immunoreactivity is associated with low-grade non-invasive urothelial bladder cancer.

Published in:

Oncology Letters, 2015, v. 10, n. 5, p. 2753, doi. 10.3892/ol.2015.3691

By:

POYET, CÉDRIC;
HERMANNS, THOMAS;
QING ZHONG;
DRESCHER, EVA;
EBERLI, DANIEL;
BURGER, MAXIMILIAN;
HOFSTAEDTER, FERDINAND;
HARTMANN, ARNDT;
STÖHR, ROBERT;
ZWARTHOFF, ELLEN C.;
SULSER, TULLIO;
WILD, PETER J.

Publication type:

Article

The MN1 oncoprotein synergizes with coactivators RAC3 and p300 in RAR-RXR-mediated transcription.

Published in:

Oncogene, 2003, v. 22, n. 5, p. 699, doi. 10.1038/sj.onc.1206124

By:

van Wely, Karel H M;
Molijn, Anco C;
Buijs, Arjan;
Meester-Smoor, Magda A;
Aarnoudse, Albert Jan;
Hellemons, Anita;
den Besten, Pim;
Grosveld, Gerard C;
Zwarthoff, Ellen C

Publication type:

Article

The clonal relation of primary upper urinary tract urothelial carcinoma and paired urothelial carcinoma of the bladder.

Published in:

International Journal of Cancer, 2021, v. 148, n. 4, p. 981, doi. 10.1002/ijc.33327

By:

Doeveren, Thomas;
Nakauma‐Gonzalez, Jose A.;
Mason, Andrew S.;
Leenders, Geert J. L. H.;
Zuiverloon, Tahlita C. M.;
Zwarthoff, Ellen C.;
Meijssen, Isabelle C.;
Made, Angelique C.;
Heijden, Antoine G.;
Hendricksen, Kees;
Rhijn, Bas W. G.;
Voskuilen, Charlotte S.;
Riet, Job;
Dinjens, Winand N. M.;
Dubbink, Hendrikus J.;
Werken, Harmen J. G.;
Boormans, Joost L.

Publication type:

Article

The Use of Molecular Analyses in Voided Urine for the Assessment of Patients with Hematuria.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077657

By:

Beukers, Willemien;
Kandimalla, Raju;
van Houwelingen, Diandra;
Kovacic, Hrvoje;
Chin, Jie-Fen D.;
Lingsma, Hester F.;
Dyrskjot, Lars;
Zwarthoff, Ellen C.

Publication type:

Article

The Leukemia-Associated Fusion Protein MN1-TEL Blocks TEL-Specific Recognition Sequences.

Published in:

PLoS ONE, 2012, v. 7, n. 9, p. 1, doi. 10.1371/journal.pone.0046085

By:

ter Haar, W. Martijn;
Meester-Smoor, Magda A.;
Van Wely, Karel H. M.;
Schot, Claudia C. M. M.;
Janssen, Marjolein J. F. W.;
Geverts, Bart;
Bonten, Jacqueline;
Grosveld, Gerard C.;
Houtsmuller, Adriaan B.;
Zwarthoff, Ellen C.;
Bunting, Kevin D.

Publication type:

Article

Selection of Microsatellite Markers for Bladder Cancer Diagnosis without the Need for Corresponding Blood.

Published in:

PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043345

By:

Van Tilborg, Angela A. G.;
Kompier, Lucie C.;
Lurkin, Irene;
Poort, Ricardo;
El Bouazzaoui, Samira;
Van Der Keur, Kirstin;
Zuiverloon, Tahlita;
Dyrskjot, Lars;
Orntoft, Torben F.;
Roobol, Monique J.;
Zwarthoff, Ellen C.;
Katoh, Masaru

Publication type:

Article

The ETS Family Member TEL Binds to Nuclear Receptors RAR and RXR and Represses Gene Activation.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0023620

By:

Meester-Smoor, Magda A.;
Janssen, Marjolein J. F. W.;
ter Haar, W. Martijn;
van Wely, Karel H. M.;
Aarnoudse, Albert-Jan L. H. J.;
van Oord, Gertine;
van Tilburg, Gabrielle B. A.;
Zwarthoff, Ellen C.

Publication type:

Article

FGFR3, HRAS, KRAS, NRAS and PIK3CA Mutations in Bladder Cancer and Their Potential as Biomarkers for Surveillance and Therapy.

Published in:

PLoS ONE, 2010, v. 5, n. 11, p. 1, doi. 10.1371/journal.pone.0013821

By:

Kompier, Lucie C.;
Lurkin, Irene;
van der Aa, Madelon N. M.;
van Rhijn, Bas W. G.;
van der Kwast, Theo H.;
Zwarthoff, Ellen C.

Publication type:

Article

Two Multiplex Assays That Simultaneously Identify 22 Possible Mutation Sites in the KRAS, BRAF, NRAS and PIK3CA Genes.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008802

By:

Lurkin, Irene;
Stoehr, Robert;
Hurst, Carolyn D.;
van Tilborg, Angela A. G.;
Knowles, Margaret A.;
Hartmann, Arndt;
Zwarthoff, Ellen C.

Publication type:

Article

Bladder cancer biomarkers and their role in surveillance and screening.

Published in:

International Journal of Urology, 2009, v. 16, n. 1, p. 23, doi. 10.1111/j.1442-2042.2008.02174.x

By:

van Tilborg, Angela A. G.;
Bangma, Chris H.;
Zwarthoff, Ellen C.

Publication type:

Article

MN1 affects expression of genes involved in hematopoiesis and can enhance as well as inhibit RAR/RXR-induced gene expression.

Published in:

Carcinogenesis, 2008, v. 29, n. 10, p. 2025, doi. 10.1093/carcin/bgn168

By:

Magda A. Meester-Smoor;
Marjolein J.F.W. Janssen;
Gerard C. Grosveld;
Annelies de Klein;
Wilfred F.J. van IJcken;
Hannie Douben;
Ellen C. Zwarthoff

Publication type:

Article

Epidermal Nevus in Association with Some Uncommon Manifestations.

Published in:

Acta Dermatovenerologica Croatica, 2013, v. 21, n. 4, p. 268

By:

Rostami, Parastoo;
Mahmoudi, Elham;
Sotoudeh, Arya;
Nakhaeimoghadam, Maryam;
Lurkin, Irene;
Zwarthoff, Ellen C.;
Rezaei, Nima

Publication type:

Article

The chromosome 9q genes TGFBR1, TSC1, and ZNF189 are rarely mutated in bladder cancer.

Published in:

Journal of Pathology, 2001, v. 194, n. 1, p. 76, doi. 10.1002/path.860

By:

van Tilborg, Angela A. G.;
de Vries, Annie;
Zwarthoff, Ellen C.

Publication type:

Article

An in vitro model of urothelial regeneration: Effects of growth factors and extracellular matrix proteins.

Published in:

Journal of Pathology, 1994, v. 173, n. 3, p. 283, doi. 10.1002/path.1711730312

By:

Rebel, Johanna M.;
de Boer, Willem I.;
Thijssen, Cornelia D.;
Vermey, Marcel;
Zwarthoff, Ellen C.;
Van der Kwast, Theodorus H.

Publication type:

Article

Targeted Disruption of the Mn1 Oncogene Results in Severe Defects in Development of Membranous Bones of the Cranial Skeleton.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 10, p. 4229, doi. 10.1128/MCB.25.10.4229-4236.2005

By:

Meester-Smoor, Magda A.;
Vermeij, Marcel;
van Helmond, Marjolein J. L.;
Molijn, Anco C.;
van Wely, Karel H. M.;
Hekman, Arnold C. P.;
Vermey-Keers, Christl;
Riegman, Peter H. J.;
Zwarthoff, Ellen C.

Publication type:

Article

Microsatellite analysis--DNA test in urine competes with cystoscopy in follow-up of superficial bladder carcinoma: a phase II trial.

Published in:

2001

By:

van Rhijn, Bas W. G.;
Lurkin, Irene;
Kirkels, Wim J.;
van der Kwast, Theodorus H.;
Zwarthoff, Ellen C.;
van Rhijn, B W;
Lurkin, I;
Kirkels, W J;
van der Kwast, T H;
Zwarthoff, E C

Publication type:

journal article

The development of multiple bladder tumour recurrences in relation to the FGFR3 mutation status of the primary tumour.

Published in:

Journal of Pathology, 2009, v. 218, n. 1, p. 104, doi. 10.1002/path.2507

By:

Kompier, Lucie C;
van der Aa, Madelon NM;
Lurkin, Irene;
Vermeij, Marcel;
Kirkels, Wim J;
Bangma, Chris H;
van der Kwast, Theodorus H;
Zwarthoff, Ellen C

Publication type:

Article

The random development of LOH on chromosome 9q in superficial bladder cancers.

Published in:

Journal of Pathology, 2002, v. 198, n. 3, p. 352, doi. 10.1002/path.1215

By:

van Tilborg, Angela AG;
de Vries, Annie;
de Bont, Maarten;
Groenfeld, Lilian E;
Zwarthoff, Ellen C

Publication type:

Article

Frequent FGFR3 mutations in urothelial papilloma.

Published in:

Journal of Pathology, 2002, v. 198, n. 2, p. 245, doi. 10.1002/path.1202

By:

van Rhijn, Bas W. G.;
Montironi, Rodolfo;
Zwarthoff, Ellen C.;
Jöbsis, Adriaan C.;
van der Kwast, Theo H.

Publication type:

Article