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HS 3D-SeboSkin Model Enables the Preclinical Exploration of Therapeutic Candidates for Hidradenitis Suppurativa/Acne Inversa.
Published in:
Pharmaceutics, 2023, v. 15, n. 2, p. 619, doi. 10.3390/pharmaceutics15020619
By:
- Zouboulis, Christos C.;
- Hou, Xiaoxiao;
- von Waldthausen, Henriette;
- Zouboulis, Konstantin C.;
- Hossini, Amir M.
Publication type:
Article
Hidradenitis Suppurativa and Comorbid Disorder Biomarkers, Druggable Genes, New Drugs and Drug Repurposing—A Molecular Meta-Analysis.
Published in:
Pharmaceutics, 2022, v. 14, n. 1, p. 44, doi. 10.3390/pharmaceutics14010044
By:
- Zouboulis, Viktor A.;
- Zouboulis, Konstantin C.;
- Zouboulis, Christos C.
Publication type:
Article
Anxiety, Depression, and Suicidal Ideation amongst Patients with Facial Dermatoses (Acne, Rosacea, Perioral Dermatitis, and Folliculitis) in Lithuania.
Published in:
2020
By:
- Lukaviciute, Laura;
- Ganceviciene, Ruta;
- Navickas, Petras;
- Navickas, Alvydas;
- Grigaitiene, Jurate;
- Zouboulis, Christos C.;
- Zouboulis, Christos C
Publication type:
journal article
Adalimumab Dose Intensification in Recalcitrant Hidradenitis Suppurativa/Acne Inversa.
Published in:
2020
By:
- Zouboulis, Christos C.;
- Hansen, Hendrik;
- Caposiena Caro, Raffaele Dante;
- Damiani, Giovanni;
- Delorme, Isabelle;
- Pascual, José Carlos;
- Reguiai, Ziad;
- Trigoni, Anastasia;
- Vilarrasa, Eva;
- Alfageme Roldán, Fernando;
- Zouboulis, Christos C;
- Caposiena Caro, Raffaele Dante;
- Pascual, José Carlos;
- Alfageme Roldán, Fernando
Publication type:
journal article
Multimodal Clinical Imaging Assessment of the Outcome in Mild-to-Moderate Acne: A Prospective Study.
Published in:
2019
By:
- Kyrgidis, Athanassios;
- Becker, Markus;
- Zampeli, Vasiliki;
- Fauger, Aurélie;
- Sayag, Michèle;
- Zouboulis, Christos C.;
- Zouboulis, Christos C
Publication type:
journal article
Long-Wave Medical Infrared Thermography: A Clinical Biomarker of Inflammation in Hidradenitis Suppurativa/Acne Inversa.
Published in:
2019
By:
- Zouboulis, Christos C.;
- Nogueira da Costa, André;
- Jemec, Gregor B.E.;
- Trebing, Dietrich;
- Zouboulis, Christos C;
- Nogueira da Costa, André;
- Jemec, Gregor B E
Publication type:
journal article
Standardized Photographic Documentation of Hidradenitis Suppurativa/Acne Inversa.
Published in:
2018
By:
- Zouboulis, Christos C.;
- Nogueira da Costa, André;
- Zouboulis, Christos C;
- Nogueira da Costa, André
Publication type:
journal article
Is Human Sebum the Source of Skin Follicular Ultraviolet-Induced Red Fluorescence? A Cellular to Histological Study.
Published in:
2018
By:
- Xu, De-Tian;
- Yan, Jian-Na;
- Liu, Wei;
- Hou, Xiao-Xiao;
- Zheng, Yan;
- Jiang, Wei-Wei;
- Ju, Qiang;
- Zouboulis, Christos C.;
- Wang, Xiu-Li;
- Zouboulis, Christos C
Publication type:
journal article
Sun exposure, a relevant exposome factor in acne patients and how photoprotection can improve outcomes.
Published in:
Journal of Cosmetic Dermatology, 2023, v. 22, n. 6, p. 1919, doi. 10.1111/jocd.15726
By:
- Piquero‐Casals, J.;
- Morgado‐Carrasco, D.;
- Rozas‐Muñoz, E.;
- Mir‐Bonafé, J. F.;
- Trullàs, C.;
- Jourdan, E.;
- Piquero‐Martin, J.;
- Zouboulis, C. C.;
- Krutmann, J.
Publication type:
Article
Lactoferrin regulates sebogenesis and inflammation in SZ95 human sebocytes and mouse model of acne.
Published in:
Journal of Cosmetic Dermatology, 2023, v. 22, n. 4, p. 1361, doi. 10.1111/jocd.15577
By:
- Su, Yuan‐Ting;
- Zouboulis, Christos C.;
- Cui, Wei;
- Zhang, An‐Ping
Publication type:
Article
Cover Image.
Published in:
Journal of Cosmetic Dermatology, 2021, v. 20, n. 3, p. ii, doi. 10.1111/jocd.13988
By:
- Lee, Yoonjin;
- Shin, Kayoung;
- Shin, Kyong‐Oh;
- Yoon, Seokjeong;
- Jung, Juyeon;
- Hwang, Eojin;
- Chung, Hwa‐Jee;
- Hossini, Amir M.;
- Zouboulis, Christos C.;
- Baek, Min Jeong;
- Baek, Ji Hwoon;
- Chi, Young Min;
- Lee, Sangeun;
- Jeong, Sekyoo
Publication type:
Article
Topical application of autophagy‐activating peptide improved skin barrier function and reduced acne symptoms in acne‐prone skin.
Published in:
Journal of Cosmetic Dermatology, 2021, v. 20, n. 3, p. 1009, doi. 10.1111/jocd.13636
By:
- Lee, Yoonjin;
- Shin, Kayoung;
- Shin, Kyong‐Oh;
- Yoon, Seokjeong;
- Jung, Juyeon;
- Hwang, Eojin;
- Chung, Hwa‐Jee;
- Hossini, Amir M.;
- Zouboulis, Christos C.;
- Baek, Min Jeong;
- Baek, Ji Hwoon;
- Chi, Young Min;
- Lee, Sangeun;
- Jeong, Sekyoo
Publication type:
Article
Demographic Data, Risk Factors, and Disease Burden of HS Patients in Lithuania at a Reference Center.
Published in:
Healthcare (2227-9032), 2024, v. 12, n. 18, p. 1849, doi. 10.3390/healthcare12181849
By:
- Raudonis, Tadas;
- Šakaitytė, Austėja;
- Vileikis, Tomas Petras;
- Černel, Vitalij;
- Gancevičiene, Rūta;
- Zouboulis, Christos C.
Publication type:
Article
Efficacy and Safety of Bimekizumab in Moderate to Severe Hidradenitis Suppurativa: A Phase 2, Double-blind, Placebo-Controlled Randomized Clinical Trial.
Published in:
2021
By:
- Glatt, Sophie;
- Jemec, Gregor B. E.;
- Forman, Seth;
- Sayed, Christopher;
- Schmieder, George;
- Weisman, Jamie;
- Rolleri, Robert;
- Seegobin, Seth;
- Baeten, Dominique;
- Ionescu, Lucian;
- Zouboulis, Christos C.;
- Shaw, Stevan
Publication type:
journal article
Prevalence of Hidradenitis Suppurativa: A Systematic Review and Meta-regression Analysis.
Published in:
2021
By:
- Jfri, Abdulhadi;
- Nassim, David;
- O'Brien, Elizabeth;
- Gulliver, Wayne;
- Nikolakis, Georgios;
- Zouboulis, Christos C.
Publication type:
journal article
Albert Montgomery Kligman-Remembering a Pioneer of Topical Treatment.
Published in:
2017
By:
- Zouboulis, Christos C.
Publication type:
journal article
miR-146a modulates TLR1/2 and 4 induced inflammation and links it with proliferation and lipid production via the indirect regulation of GNG7 in human SZ95 sebocytes.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-00907-1
By:
- Dull, Katalin;
- Fazekas, Fruzsina;
- Deák, Dávid;
- Kovács, Dóra;
- Póliska, Szilárd;
- Szegedi, Andrea;
- Zouboulis, Christos C.;
- Törőcsik, Dániel
Publication type:
Article
Impressive skin manifestation of systemic sarcoidosis.
Published in:
International Journal of Dermatology, 2002, v. 41, n. 4, p. 232, doi. 10.1046/j.1365-4362.2002.14141.x
By:
- Chandani, A. M. H. A. Janitha P;
- Adler, Yael D;
- Dippel, Edgar;
- Zouboulis, Christos C
Publication type:
Article
Is There a Role for Antiandrogen Therapy for Hidradenitis Suppurativa? A Systematic Review of Published Data.
Published in:
American Journal of Clinical Dermatology, 2019, v. 20, n. 4, p. 503, doi. 10.1007/s40257-019-00442-w
By:
- Nikolakis, Georgios;
- Kyrgidis, Athanassios;
- Zouboulis, Christos C.
Publication type:
Article
Malignant atrophic papulosis (Köhlmeier-Degos disease) - A review.
Published in:
Orphanet Journal of Rare Diseases, 2013, v. 8, n. 1, p. 1, doi. 10.1186/1750-1172-8-10
By:
- Theodoridis, Athanasios;
- Makrantonaki, Evgenia;
- Zouboulis, Christos C
Publication type:
Article
Malignant atrophic papulosis (Köhlmeier-Degos disease) - a review.
Published in:
2013
By:
- Theodoridis, Athanasios;
- Makrantonaki, Evgenia;
- Zouboulis, Christos C
Publication type:
journal article
Bee Venom and Its Major Component Melittin Attenuated Cutibacterium acnes - and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway.
Published in:
International Journal of Molecular Sciences, 2022, v. 23, n. 6, p. 3152, doi. 10.3390/ijms23063152
By:
- Gu, Hyemin;
- An, Hyun-Jin;
- Gwon, Mi-Gyeong;
- Bae, Seongjae;
- Leem, Jaechan;
- Lee, Sun-Jae;
- Han, Sang-Mi;
- Zouboulis, Christos C.;
- Park, Kwan-Kyu
Publication type:
Article
Anti-Inflammatory and Pro-Differentiating Properties of the Aryl Hydrocarbon Receptor Ligands NPD-0614-13 and NPD-0614-24: Potential Therapeutic Benefits in Psoriasis.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 14, p. 7501, doi. 10.3390/ijms22147501
By:
- Cardinali, Giorgia;
- Flori, Enrica;
- Mastrofrancesco, Arianna;
- Mosca, Sarah;
- Ottaviani, Monica;
- Dell'Anna, Maria Lucia;
- Truglio, Mauro;
- Vento, Antonella;
- Zaccarini, Marco;
- Zouboulis, Christos C.;
- Picardo, Mauro
Publication type:
Article
Histone Deacetylase 1 Reduces Lipogenesis by Suppressing SREBP1 Transcription in Human Sebocyte Cell Line SZ95.
Published in:
International Journal of Molecular Sciences, 2021, v. 22, n. 9, p. 4477, doi. 10.3390/ijms22094477
By:
- Shin, Hye Sun;
- Lee, Yuri;
- Shin, Mi Hee;
- Cho, Soo Ick;
- Zouboulis, Christos C.;
- Kim, Min Kyoung;
- Lee, Dong Hun;
- Chung, Jin Ho;
- Barreto, George E.
Publication type:
Article
Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.
Published in:
2014
By:
- Oláh, Attila;
- Tóth, Balázs I;
- Borbíró, István;
- Sugawara, Koji;
- Szöllõsi, Attila G;
- Czifra, Gabriella;
- Pál, Balázs;
- Ambrus, Lídia;
- Kloepper, Jennifer;
- Camera, Emanuela;
- Ludovici, Matteo;
- Picardo, Mauro;
- Voets, Thomas;
- Zouboulis, Christos C;
- Paus, Ralf;
- Bíró, Tamás
Publication type:
journal article
Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes.
Published in:
Journal of Clinical Investigation, 2014, v. 124, n. 9, p. 3713, doi. 10.1172/JCI64628
By:
- Oláh, Attila;
- Tóth, Balázs I.;
- Borbíró, István;
- Sugawara, Koji;
- Szöllõsi, Attila G.;
- Czifra, Gabriella;
- Pál, Balázs;
- Ambrus, Lídia;
- Kloepper, Jennifer;
- Camera, Emanuela;
- Ludovici, Matteo;
- Picardo, Mauro;
- Voets, Thomas;
- Zouboulis, Christos C.;
- Paus, Ralf;
- Bíró, Tamás
Publication type:
Article
Exosomes from adipose-derived stem cells activate sebocytes through the PI3K/AKT/SREBP-1 pathway to accelerate wound healing.
Published in:
Cell & Tissue Research, 2024, v. 396, n. 3, p. 329, doi. 10.1007/s00441-024-03872-z
By:
- Zhang, Yingbo;
- Zouboulis, Christos C.;
- Xiao, Zhibo
Publication type:
Article
Endothelins and α‐melanocyte‐stimulating hormone are increased in plasma of patients treated with UVA1 and psoralen plus UVA.
Published in:
Photodermatology, Photoimmunology & Photomedicine, 2022, v. 38, n. 6, p. 611, doi. 10.1111/phpp.12789
By:
- Abdel‐Naser, M. Badawy;
- Seltmann, Holger;
- Altenburg, Andreas;
- Zouboulis, Christos C.
Publication type:
Article
Efficacy and Safety of Adalimumab in Conjunction With Surgery in Moderate to Severe Hidradenitis Suppurativa: The SHARPS Randomized Clinical Trial.
Published in:
2021
By:
- Bechara, Falk G.;
- Podda, Maurizio;
- Prens, Errol P.;
- Horváth, Barbara;
- Giamarellos-Bourboulis, Evangelos J.;
- Alavi, Afsaneh;
- Szepietowski, Jacek C.;
- Kirby, Joslyn;
- Geng, Ziqian;
- Jean, Christine;
- Jemec, Gregor B. E.;
- Zouboulis, Christos C.
Publication type:
journal article
Switching from Adalimumab Originator to Biosimilar in Patients with Hidradenitis Suppurativa Results in Losses of Response—Data from the German HS Registry HSBest.
Published in:
Life (2075-1729), 2022, v. 12, n. 10, p. 1518, doi. 10.3390/life12101518
By:
- Kirsten, Natalia;
- Ohm, Frenz;
- Gehrdau, Kathrin;
- Girbig, Gefion;
- Stephan, Brigitte;
- Ben-Anaya, Nesrine;
- Pinter, Andreas;
- Bechara, Falk G.;
- Presser, Dagmar;
- Zouboulis, Christos C.;
- Augustin, Matthias
Publication type:
Article
Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.1029818
By:
- Zouboulis, Christos C.;
- Coenye, Tom;
- Li He;
- Kenji Kabashima;
- Tetsuro Kobayashi;
- Niemann, Catherin;
- Takashi Nomura;
- Oláh, Attila;
- Picardo, Mauro;
- Quist, Sven R.;
- Hironobu Sasano;
- Schneider, Marlon R.;
- Törőcsik, Daniel;
- Wong, Sunny Y.
Publication type:
Article
Characterization of Bipotential Epidermal Progenitors Derived from Human Sebaceous Gland: Contrasting Roles of c-Myc and β-Catenin.
Published in:
Stem Cells, 2008, v. 26, n. 5, p. 1241, doi. 10.1634/stemcells.2007-0651
By:
- CELSO, CRISTINA LO;
- BERTA, MELANIE A.;
- BRAUN, KRISTIN M.;
- FRYE, MICHAELA;
- LYLE, STEPHEN;
- ZOUBOULIS, CHRISTOS C.;
- WATT, FIONA M.
Publication type:
Article
Human sebaceous tumors harbor inactivating mutations in LEF1.
Published in:
Nature Medicine, 2006, v. 12, n. 4, p. 395, doi. 10.1038/nm1386
By:
- Takeda, Hikaru;
- Lyle, Stephen;
- Lazar, Alexander J. F.;
- Zouboulis, Christos C.;
- Smyth, Ian;
- Watt, Fiona M.
Publication type:
Article
Molecular Mechanisms of Skin Aging.
Published in:
Annals of the New York Academy of Sciences, 2007, v. 1119, p. 40, doi. 10.1196/annals.1404.027
By:
- MAKRANTONAKI, E.;
- ZOUBOULIS, C. C.
Publication type:
Article
Diabetes mellitus and the skin.
Published in:
Reviews in Endocrine & Metabolic Disorders, 2016, v. 17, n. 3, p. 269, doi. 10.1007/s11154-016-9373-0
By:
- Makrantonaki, E.;
- Jiang, D.;
- Hossini, A.;
- Nikolakis, G.;
- Wlaschek, M.;
- Scharffetter-Kochanek, K.;
- Zouboulis, C.
Publication type:
Article
The Global Hidradenitis Suppurativa Atlas Methodology: Combining Global Proportions in a Pooled Analysis.
Published in:
Dermatology (10188665), 2024, v. 240, n. 3, p. 369, doi. 10.1159/000536389
By:
- Bouazzi, Dorra;
- Andersen, Rune K.;
- Vinding, Gabrielle R.;
- Medianfar, Cecilia E.;
- Nielsen, Sabrina M.;
- Saunte, Ditte M.L.;
- Chandran, Nisha S.;
- van der Zee, Hessel H.;
- Zouboulis, Christos C.;
- Benhadou, Farida;
- Villumsen, Bente;
- Alavi, Afsaneh;
- Ibekwe, Perpetua U.;
- Hamzavi, Iltefat H.;
- Ingram, John R.;
- Naik, Haley B.;
- Garg, Amit;
- Boer, Jurr;
- Christensen, Robin;
- Jemec, Gregor B.E.
Publication type:
Article
Viewpoint on the Evaluation of Severity and Treatment Effects in Mild Hidradenitis Suppurativa: The Cumulative IHS4.
Published in:
2024
By:
- van der Zee, Hessel H.;
- van Huijstee, Johanna C.;
- van Straalen, Kelsey R.;
- Jemec, Gregor B.E.;
- Zouboulis, Christos C.;
- Tzellos, Thrasyvoulos;
- Prens, Errol P.
Publication type:
Question & Answer
Chronic Inflammatory Intestinal Disorders in Hidradenitis Suppurativa.
Published in:
Dermatology (10188665), 2023, v. 239, n. 4, p. 592, doi. 10.1159/000530434
By:
- Réka, Palatka;
- Janka, Eszter Anna;
- Soltész, Lilla;
- Szabó, Imre Lőrinc;
- Kapitány, Anikó;
- Dajnoki, Zsolt;
- Emri, Gabriella;
- Nagy, Gábor;
- Palatka, Károly;
- Zouboulis, Christos C.;
- Szegedi, Andrea;
- Gáspár, Krisztián
Publication type:
Article
Which Health-Related Quality of Life Items Most Affect Acne Patients?
Published in:
Dermatology (10188665), 2023, v. 239, n. 2, p. 267, doi. 10.1159/000526602
By:
- Chernyshov, Pavel V.;
- Sampogna, Francesca;
- Zouboulis, Christos C.;
- Boffa, Michael J.;
- Marron, Servando E.;
- Manolache, Liana;
- Pustišek, Nives;
- Bettoli, Vincenzo;
- Koumaki, Dimitra;
- Chubar, Olha;
- Pochynok, Tetiana V.;
- Mintoff, Dillon;
- Bonitsis, Nikolaos G.;
- Spillekom-van Koulil, Saskia;
- Driessen, Rieke J.B.;
- Chernyshov, Andriy V.;
- Bewley, Anthony Paul;
- Evers, Andrea W.M.;
- Chernyshov, Ivan P.;
- Tomas-Aragones, Lucia
Publication type:
Article
3D-SeboSkin Model for Human ex vivo Studies of Hidradenitis Suppurativa/Acne Inversa.
Published in:
Dermatology (10188665), 2022, v. 238, n. 2, p. 236, doi. 10.1159/000515955
By:
- Hou, Xiaoxiao;
- Hossini, Amir M.;
- Nikolakis, Georgios;
- Balthasar, Ottfried;
- Kurtz, Andreas;
- Zouboulis, Christos C.
Publication type:
Article
Metabolic Disorders/Obesity Is a Primary Risk Factor in Hidradenitis Suppurativa: An Immunohistochemical Real-World Approach.
Published in:
Dermatology (10188665), 2022, v. 238, n. 2, p. 251, doi. 10.1159/000517017
By:
- Kaleta, Katarzyna P.;
- Nikolakis, Georgios;
- Hossini, Amir M.;
- Balthasar, Ottfried;
- Almansouri, Daifallah;
- Vaiopoulos, Aristeidis;
- Knolle, Jürgen;
- Boguslawska, Anna;
- Wojas-Pelc, Anna;
- Zouboulis, Christos C.
Publication type:
Article
Different Types of Auricular Keloids and Treatment by Intralesional Cryosurgery: Best Practice for Obtaining Long-Lasting Clinical Results.
Published in:
Dermatology (10188665), 2022, v. 238, n. 1, p. 170, doi. 10.1159/000514954
By:
- Har-Shai, Yaron;
- Har-Shai, Lior;
- Zouboulis, Viktor A.;
- Zouboulis, Christos C.
Publication type:
Article
Phenotypes and Pathophysiology of Syndromic Hidradenitis Suppurativa: Different Faces of the Same Disease? A Systematic Review.
Published in:
Dermatology (10188665), 2021, v. 237, n. 5, p. 673, doi. 10.1159/000509873
By:
- Nikolakis, Georgios;
- Kaleta, Katarzyna P.;
- Vaiopoulos, Aristeidis G.;
- Wolter, Katja;
- Baroud, Sumer;
- Wojas-Pelc, Anna;
- Zouboulis, Christos C.
Publication type:
Article
The Pro-Differentiation Effect of Doxycycline on Human SZ95 Sebocytes.
Published in:
Dermatology (10188665), 2021, v. 237, n. 5, p. 792, doi. 10.1159/000510885
By:
- Zouboulis, Christos C.;
- Ní Raghallaigh, Síona;
- Schmitz, Gerd;
- Powell, Frank C.
Publication type:
Article
Cryosurgery as a Single Agent and in Combination with Intralesional Corticosteroids Is Effective on Young, Small Keloids and Induces Characteristic Histological and Immunohistological Changes: A Prospective Randomized Trial.
Published in:
Dermatology (10188665), 2021, v. 237, n. 3, p. 396, doi. 10.1159/000511624
By:
- Zouboulis, Christos C.;
- Zouridaki, Eftychia
Publication type:
Article
Increased Lipid Accumulation under Hypoxia in SZ95 Human Sebocytes.
Published in:
Dermatology (10188665), 2021, v. 237, n. 1, p. 131, doi. 10.1159/000505537
By:
- Choi, KeunOh;
- Jin, Mirim;
- Zouboulis, Christos C.;
- Lee, YoungJoo
Publication type:
Article
Acne Fulminans: Treatment Experience from 26 Patients.
Published in:
2017
By:
- Massa, antónio F.;
- Burmeister, Lena;
- Bass, Dirk;
- Zouboulis, Christos C.
Publication type:
journal article
Epidemiology of Acne Vulgaris in 18-Year-Old Male Army Conscripts in a South Brazilian City.
Published in:
2017
By:
- Pereira Duquia, Rodrigo;
- da Silva dos Santos, Iná;
- de almeida Jr., Hiram;
- Martins Souza, Paulo Ricardo;
- de avelar Breunig, Juliano;
- Zouboulis, Christos C.
Publication type:
journal article
Increased Activity and Number of Epidermal Melanocytes in Lesional Psoriatic Skin.
Published in:
2016
By:
- abdel-Naser, Mohamed Badawy;
- Liakou, aikaterini I.;
- Elewa, Rana;
- Hippe, Sabine;
- Knolle, Jürgen;
- Zouboulis, Christos C.
Publication type:
journal article
Marked Reduction of the Number and Individual Volume of Sebaceous Glands in Psoriatic Lesions.
Published in:
2016
By:
- Liakou, aikaterini I.;
- Nyengaard, Jens R.;
- Bonovas, Stefanos;
- Knolle, Juergen;
- Makrantonaki, Evgenia;
- Zouboulis, Christos C.
Publication type:
journal article

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