Works by Zidar, Nace

Results: 28

Rational design of balanced dual-targeting antibiotics with limited resistance.

Published in:

PLoS Biology, 2020, v. 18, n. 10, p. 1, doi. 10.1371/journal.pbio.3000819

By:

Nyerges, Akos;
Tomašič, Tihomir;
Durcik, Martina;
Revesz, Tamas;
Szili, Petra;
Draskovits, Gabor;
Bogar, Ferenc;
Skok, Žiga;
Zidar, Nace;
Ilaš, Janez;
Zega, Anamarija;
Kikelj, Danijel;
Daruka, Lejla;
Kintses, Balint;
Vasarhelyi, Balint;
Foldesi, Imre;
Kata, Diána;
Welin, Martin;
Kimbung, Raymond;
Focht, Dorota

Publication type:

Article

Design, synthesis, and biological evaluation of 1-ethyl-3-(thiazol-2-yl)urea derivatives as Escherichia coli DNA gyrase inhibitors.

Published in:

Archiv der Pharmazie, 2018, v. 351, n. 1, p. n/a, doi. 10.1002/ardp.201700333

By:

Tomašič, Tihomir;
Barančoková, Michaela;
Zidar, Nace;
Ilaš, Janez;
Tammela, Päivi;
Kikelj, Danijel

Publication type:

Article

A synthetic flavonoid derivate in the plasma membrane transforms the voltage‐clamp fluorometry signal of CiHv1.

Published in:

FEBS Journal, 2024, v. 291, n. 11, p. 2354, doi. 10.1111/febs.17105

By:

Pethő, Zoltán;
Pajtás, Dávid;
Piga, Martina;
Magyar, Zsuzsanna;
Zakany, Florina;
Kovacs, Tamas;
Zidar, Nace;
Panyi, Gyorgy;
Varga, Zoltan;
Papp, Ferenc

Publication type:

Article

Cover Feature: Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity (ChemMedChem 3/2020).

Published in:

ChemMedChem, 2020, v. 15, n. 3, p. 264, doi. 10.1002/cmdc.202000031

By:

Fois, Benedetta;
Skok, Žiga;
Tomašič, Tihomir;
Ilaš, Janez;
Zidar, Nace;
Zega, Anamarija;
Peterlin Mašič, Lucija;
Szili, Petra;
Draskovits, Gábor;
Nyerges, Ákos;
Pál, Csaba;
Kikelj, Danijel

Publication type:

Article

Dual Escherichia coli DNA Gyrase A and B Inhibitors with Antibacterial Activity.

Published in:

ChemMedChem, 2020, v. 15, n. 3, p. 265, doi. 10.1002/cmdc.201900607

By:

Fois, Benedetta;
Skok, Žiga;
Tomašič, Tihomir;
Ilaš, Janez;
Zidar, Nace;
Zega, Anamarija;
Peterlin Mašič, Lucija;
Szili, Petra;
Draskovits, Gábor;
Nyerges, Ákos;
Pál, Csaba;
Kikelj, Danijel

Publication type:

Article

Synthesis and Evaluation of <italic>N</italic>‐Phenylpyrrolamides as DNA Gyrase B Inhibitors.

Published in:

ChemMedChem, 2018, v. 13, n. 2, p. 186, doi. 10.1002/cmdc.201700549

By:

Durcik, Martina;
Tammela, Päivi;
Barančoková, Michaela;
Tomašič, Tihomir;
Ilaš, Janez;
Kikelj, Danijel;
Zidar, Nace

Publication type:

Article

A New Cell‐Based AI‐2‐Mediated Quorum Sensing Interference Assay in Screening of LsrK‐Targeted Inhibitors.

Published in:

ChemBioChem, 2020, v. 21, n. 13, p. 1918, doi. 10.1002/cbic.201900773

By:

Gatta, Viviana;
Tomašič, Tihomir;
Ilaš, Janez;
Zidar, Nace;
Peterlin Mašič, Lucija;
Barančoková, Michaela;
Frlan, Rok;
Anderluh, Marko;
Kikelj, Danijel;
Tammela, Päivi

Publication type:

Article

Evaluation of Michael-type Acceptor Reactivity of 5-Benzylidenebarbiturates, 5-benzylidenerhodanines, and Related Heterocycles Using NMR.

Published in:

Acta Chimica Slovenica, 2014, v. 61, n. 3, p. 637

By:

Arsovska, Emilija;
Trontelj, Jurij;
Zidar, Nace;
Tomašič, Tihomir;
Mašič, Lucija Peterlin;
Kikelj, Danijel;
Plavec, Janez;
Zega, Anamarija

Publication type:

Article

Preparation and Reactivity of 5-benzylidenebarbituric and 5-benzylidene-2-thiobarbituric Acids.

Published in:

Acta Chimica Slovenica, 2011, v. 58, n. 1, p. 151

By:

Zidar, Nace;
Kikelj, Danijel

Publication type:

Article

A Convenient Synthesis of 4-Benzyl-2-(2-(4-oxo-2-thioxothiazolidin-5-ylidene)ethyl)-2H-1,4-benzoxazin- 3(4H)-ones and 5-(2-(4-Benzyl-3-oxo-3,4-dihydro-2H- 1,4-benzoxazin-2-yl)ethylidene)thiazolidine-2,4-diones.

Published in:

Acta Chimica Slovenica, 2009, v. 56, n. 3, p. 635

By:

Zidar, Nace;
Kladnik, Jure;
Kikelj, Danijel

Publication type:

Article

Neuroinflammation-Induced Upregulation of Glial Cathepsin X Expression and Activity in vivo.

Published in:

Frontiers in Molecular Neuroscience, 2020, v. 13, p. N.PAG, doi. 10.3389/fnmol.2020.575453

By:

Pišlar, Anja;
Tratnjek, Larisa;
Glavan, Gordana;
Zidar, Nace;
Živin, Marko;
Kos, Janko

Publication type:

Article

Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels.

Published in:

Marine Drugs, 2014, v. 12, n. 6, p. 2132, doi. 10.3390/md12042132

By:

Peigneur, Steve;
Žula, Aleš;
Zidar, Nace;
Chan-Porter, Fiona;
Kirby, Robert;
Madge, David;
Ilaš, Janez;
Kikelj, Danijel;
Tytgat, Jan

Publication type:

Article

Action of Clathrodin and Analogues on Voltage-Gated Sodium Channels.

Published in:

Marine Drugs, 2014, v. 12, n. 4, p. 2132, doi. 10.3390/md12042132

By:

Peigneur, Steve;
Žula, Aleš;
Zidar, Nace;
Chan-Porter, Fiona;
Kirby, Robert;
Madge, David;
Ilaš, Janez;
Kikelj, Danijel;
Tytgat, Jan

Publication type:

Article

Antimicrobial Activity of the Marine Alkaloids, Clathrodin and Oroidin, and Their Synthetic Analogues.

Published in:

Marine Drugs, 2014, v. 12, n. 2, p. 940, doi. 10.3390/md12020940

By:

Zidar, Nace;
Montalvão, Sofia;
Hodnik, Žiga;
Nawrot, Dorota A.;
Žula, Aleš;
Ilaš, Janez;
Kikelj, Danijel;
Tammela, Päivi;
Mašič, Lucija Peterlin

Publication type:

Article

Characterization of Endogenous Sodium Channels in the ND7-23 Neuroblastoma Cell Line: Implications for Use as a Heterologous Ion Channel Expression System Suitable for Automated Patch Clamp Screening.

Published in:

Assay & Drug Development Technologies, 2016, v. 14, n. 2, p. 109, doi. 10.1089/adt.2016.704

By:

Rogers, Marc;
Zidar, Nace;
Kikelj, Danijel;
Kirby, Robert W.

Publication type:

Article

Overcoming problems of poor drug penetration into bacteria: challenges and strategies for medicinal chemists.

Published in:

Expert Opinion on Drug Discovery, 2018, v. 13, n. 6, p. 497, doi. 10.1080/17460441.2018.1455660

By:

Benedetto Tiz, Davide;
Kikelj, Danijel;
Zidar, Nace

Publication type:

Article

Upregulation of Cathepsin X in Glioblastoma: Interplay with γ-Enolase and the Effects of Selective Cathepsin X Inhibitors.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 3, p. 1784, doi. 10.3390/ijms23031784

By:

Majc, Bernarda;
Habič, Anamarija;
Novak, Metka;
Rotter, Ana;
Porčnik, Andrej;
Mlakar, Jernej;
Župunski, Vera;
Fonović, Urša Pečar;
Knez, Damijan;
Zidar, Nace;
Gobec, Stanislav;
Kos, Janko;
Turnšek, Tamara Lah;
Pišlar, Anja;
Breznik, Barbara

Publication type:

Article

Cysteine Peptidase Cathepsin X as a Therapeutic Target for Simultaneous TLR3/4-mediated Microglia Activation.

Published in:

Molecular Neurobiology, 2022, v. 59, n. 4, p. 2258, doi. 10.1007/s12035-021-02694-2

By:

Pišlar, Anja;
Nedeljković, Biljana Božić;
Perić, Mina;
Jakoš, Tanja;
Zidar, Nace;
Kos, Janko

Publication type:

Article

Convergent Domino Knoevenagel Hetero- DielsAlder and Domino Oxidation Hetero- DielsAlder Reactions Encountered in an Unexpected Formation of Novel 5-Aryl-1 H-pyrano[2,3- d]pyrimidine-2,4(3 H,5 H)-diones and 5-Aryl-2,3-dihydro-2-thioxo-1 H-pyrano[2,3- d]pyrimidin-4(5 H)-ones

Published in:

Helvetica Chimica Acta, 2011, v. 94, n. 5, p. 859, doi. 10.1002/hlca.201000325

By:

Zidar, Nace;
Kikelj, Danijel

Publication type:

Article

Benzoxazine Series of Histidine Kinase Inhibitors as Potential Antimicrobial Agents with Activity against Enterococci.

Published in:

Chemotherapy (0009-3157), 2009, v. 55, n. 6, p. 414, doi. 10.1159/000263228

By:

Mueller-Premru, Manica;
Zidar, Nace;
Špik, Vesna Cvitković;
Krope, Adrijana;
Kikelj, Danijel

Publication type:

Article

Structure-Activity Relationships of Benzothiazole-Based Hsp90 C-Terminal-Domain Inhibitors.

Published in:

Pharmaceutics, 2021, v. 13, n. 8, p. 1283, doi. 10.3390/pharmaceutics13081283

By:

Dernovšek, Jaka;
Zajec, Živa;
Durcik, Martina;
Mašič, Lucija Peterlin;
Gobec, Martina;
Zidar, Nace;
Tomašič, Tihomir

Publication type:

Article

Hybrid Inhibitors of DNA Gyrase A and B: Design, Synthesis and Evaluation.

Published in:

Pharmaceutics, 2021, v. 13, n. 1, p. 6, doi. 10.3390/pharmaceutics13010006

By:

Durcik, Martina;
Skok, Žiga;
Ilaš, Janez;
Zidar, Nace;
Zega, Anamarija;
Szili, Petra Éva;
Draskovits, Gábor;
Révész, Tamás;
Kikelj, Danijel;
Nyerges, Akos;
Pál, Csaba;
Mašič, Lucija Peterlin;
Tomašič, Tihomir

Publication type:

Article

Enhancing Antibacterial Efficacy: Combining Novel Bacterial Topoisomerase Inhibitors with Efflux Pump Inhibitors and Other Agents Against Gram-Negative Bacteria.

Published in:

Antibiotics (2079-6382), 2024, v. 13, n. 11, p. 1081, doi. 10.3390/antibiotics13111081

By:

Zorman, Maša;
Kokot, Maja;
Zdovc, Irena;
Senerovic, Lidija;
Mandic, Mina;
Zidar, Nace;
Cotman, Andrej Emanuel;
Durcik, Martina;
Peterlin Mašič, Lucija;
Minovski, Nikola;
Anderluh, Marko;
Hrast Rambaher, Martina

Publication type:

Article

ATP-competitive DNA gyrase and topoisomerase IV inhibitors as antibacterial agents.

Published in:

Expert Opinion on Therapeutic Patents, 2019, v. 29, n. 3, p. 171, doi. 10.1080/13543776.2019.1575362

By:

Durcik, Martina;
Tomašič, Tihomir;
Zidar, Nace;
Zega, Anamarija;
Kikelj, Danijel;
Mašič, Lucija Peterlin;
Ilaš, Janez

Publication type:

Article

Synthesis of Thicolchicine‐Based Conjugates: Investigation towards Bivalent Tubulin/Microtubules Binders.

Published in:

ChemPlusChem, 2019, v. 84, n. 1, p. 98, doi. 10.1002/cplu.201800497

By:

Bonandi, Elisa;
Foschi, Francesca;
Marucci, Cristina;
Dapiaggi, Federico;
Sironi, Maurizio;
Pieraccini, Stefano;
Christodoulou, Michael S.;
de Asís Balaguer, Francisco;
Díaz, J. Fernando;
Zidar, Nace;
Passarella, Daniele

Publication type:

Article

Three-dimensional invasion of macrophages is mediated by cysteine cathepsins in protrusive podosomes.

Published in:

European Journal of Immunology, 2012, v. 42, n. 12, p. 3429, doi. 10.1002/eji.201242610

By:

Jevnikar, Zala;
Mirković, Bojana;
Fonović, Urša Pečar;
Zidar, Nace;
Švajger, Urban;
Kos, Janko

Publication type:

Article

High-performance liquid chromatography evaluation of lipophilicity and QSRR modeling of a series of dual DNA gyrase and topoisomerase IV inhibitors.

Published in:

Acta Chromatographica, 2024, v. 36, n. 1, p. 45, doi. 10.1556/1326.2022.01096

By:

Dobričić, Vladimir;
Savić, Jelena;
Tomašič, Tihomir;
Durcik, Martina;
Zidar, Nace;
Mašič, Lucija Peterlin;
Ilaš, Janez;
Kikelj, Danijel;
Čudina, Olivera

Publication type:

Article

The Carboxypeptidase Activity of Cathepsin X is not Controlled by Endogenous Inhibitors.

Published in:

Acta Chimica Slovenica, 2019, v. 66, n. 1, p. 58, doi. 10.17344/acsi.2018.4427

By:

Fonović, Urša Pečar;
Nanut, Milica Perišić;
Zidar, Nace;
Lenarčič, Brigita;
Kos, Janko

Publication type:

Article