Found: 17
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CRISPR/Cas9: Implications for Modeling and Therapy of Neurodegenerative Diseases.
- Published in:
- Frontiers in Molecular Neuroscience, 2016, p. 1, doi. 10.3389/fnmol.2016.00030
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- Article
Suppressing UBE2N ameliorates Alzheimer's disease pathology through the clearance of amyloid beta.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 9, p. 6287, doi. 10.1002/alz.14122
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- Article
Promoting Cas9 degradation reduces mosaic mutations in non-human primate embryos.
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- Scientific Reports, 2017, p. 42081, doi. 10.1038/srep42081
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- Article
A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin.
- Published in:
- Advanced Science, 2023, v. 10, n. 31, p. 1, doi. 10.1002/advs.202301120
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- Article
A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin (Adv. Sci. 31/2023).
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- Advanced Science, 2023, v. 10, n. 31, p. 1, doi. 10.1002/advs.202370210
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- Article
Maternal valproic acid exposure leads to neurogenesis defects and autism-like behaviors in non-human primates.
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- Translational Psychiatry, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41398-019-0608-1
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- Article
Large animal models for Huntington’s disease research.
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- Zoological Research, 2024, v. 45, n. 2, p. 275, doi. 10.24272/j.issn.2095-8137.2023.199
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- Article
TBN improves motor function and prolongs survival in a TDP-43<sup>M337V</sup> mouse model of ALS.
- Published in:
- Human Molecular Genetics, 2021, v. 30, n. 16, p. 1484, doi. 10.1093/hmg/ddab101
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- Article
CRISPR/Cas9-mediated disruption of SHANK3 in monkey leads to drug-treatable autism-like symptoms.
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- Human Molecular Genetics, 2019, v. 28, n. 4, p. 561, doi. 10.1093/hmg/ddy367
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- Article
Functional disruption of the dystrophin gene in rhesus monkey using CRISPR/Cas9.
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- Human Molecular Genetics, 2015, v. 24, n. 13, p. 3764, doi. 10.1093/hmg/ddv120
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- Article
Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.
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- Human Molecular Genetics, 2015, v. 24, n. 5, p. 1350, doi. 10.1093/hmg/ddu544
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- Article
PINK1 kinase dysfunction triggers neurodegeneration in the primate brain without impacting mitochondrial homeostasis.
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- Protein & Cell, 2022, v. 13, n. 1, p. 26, doi. 10.1007/s13238-021-00888-x
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- Article
CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases.
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- Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0031-x
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- Article
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys.
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- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01601-6
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- Article
Generation of inactivated IL2RG and RAG1 monkeys with severe combined immunodeficiency using base editing.
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- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01544-y
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- Article
CHD8 mutations increase gliogenesis to enlarge brain size in the nonhuman primate.
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- Cell Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41421-023-00525-3
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- Article
Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain.
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- Journal of Neuroscience, 2015, v. 35, n. 21, p. 8345, doi. 10.1523/JNEUROSCI.0772-15.2015
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- Article