Works by Zharkovsky, Alexander

Results: 31

Characterization of IMG Microglial Cell Line as a Valuable In Vitro Tool for NLRP3 Inflammasome Studies.

Published in:

Cellular & Molecular Neurobiology, 2023, v. 43, n. 5, p. 2053, doi. 10.1007/s10571-022-01285-6

By:

Viil, Janeli;
Somelar-Duracz, Kelli;
Jaako, Külli;
Anier, Kaili;
Zharkovsky, Alexander

Publication type:

Article

CSF1R regulates schizophrenia-related stress response and vascular association of microglia/macrophages.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-02959-8

By:

Yan, Ling;
Li, Yanli;
Fan, Fengmei;
Gou, Mengzhuang;
Xuan, Fangling;
Feng, Wei;
Chithanathan, Keerthana;
Li, Wei;
Huang, Junchao;
Li, Hongna;
Chen, Wenjin;
Tian, Baopeng;
Wang, Zhiren;
Tan, Shuping;
Zharkovsky, Alexander;
Hong, L. Elliot;
Tan, Yunlong;
Tian, Li

Publication type:

Article

Glucocorticoid Receptor Stimulation Resulting from Early Life Stress Affects Expression of DNA Methyltransferases in Rat Prefrontal Cortex.

Published in:

Journal of Molecular Neuroscience, 2019, v. 68, n. 1, p. 99, doi. 10.1007/s12031-019-01286-z

By:

Urb, Mari;
Anier, Kaili;
Matsalu, Terje;
Aonurm-Helm, Anu;
Tasa, Gunnar;
Koppel, Indrek;
Zharkovsky, Alexander;
Timmusk, Tõnis;
Kalda, Anti

Publication type:

Article

Distinct effects of atypical 1,4-dihydropyridines on 1-methyl-4-phenylpyridinium-induced toxicity.

Published in:

Cell Biochemistry & Function, 2007, v. 25, n. 1, p. 15, doi. 10.1002/cbf.1340

By:

Klimaviciusa, Linda;
Klusa, Vija;
Duburs, Gunars;
Kaasik, Allen;
Kalda, Anti;
Zharkovsky, Alexander

Publication type:

Article

Neuroprotective properties of a novel, non-haematopoietic agonist of the erythropoietin receptor.

Published in:

Brain: A Journal of Neurology, 2010, v. 133, n. 8, p. 2281, doi. 10.1093/brain/awq101

By:

Pankratova, Stanislava;
Kiryushko, Darya;
Sonn, Katrin;
Soroka, Vladislav;
Køhler, Lene B.;
Rathje, Mette;
Gu, Bing;
Gotfryd, Kamil;
Clausen, Ole;
Zharkovsky, Alexander;
Bock, Elisabeth;
Berezin, Vladimir

Publication type:

Article

S-adenosylmethionine modifies cocaine-induced DNA methylation and increases locomotor sensitization in mice.

Published in:

International Journal of Neuropsychopharmacology, 2013, v. 16, n. 9, p. 2053, doi. 10.1017/S1461145713000394

By:

Anier, Kaili;
Zharkovsky, Alexander;
Kalda, Anti

Publication type:

Article

Analysis of potential interactions between warfarin and prescriptions in Estonian outpatients aged 50 years or more.

Published in:

2012

By:

Gavronski, Maia;
Hartikainen, Sirpa;
Zharkovsky, Alexander

Publication type:

Journal Article

Analysis of potential interactions between warfarin and prescriptions in Estonian outpatients aged 50 years or more.

Published in:

Pharmacy Practice (1886-3655), 2012, v. 10, n. 1, p. 9, doi. 10.4321/S1886-36552012000100003

By:

GAVRONSKI, Maia;
HARTIKAINEN, Sirpa;
ZHARKOVSKY, Alexander

Publication type:

Article

DNA Methylation Regulates Cocaine-Induced Behavioral Sensitization in Mice.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 12, p. 2450, doi. 10.1038/npp.2010.128

By:

Anier, Kaili;
Malinovskaja, Kristina;
Aonurm-Helm, Anu;
Zharkovsky, Alexander;
Kalda, Anti

Publication type:

Article

Sex-Specific Microglial Activation and SARS-CoV-2 Receptor Expression Induced by Chronic Unpredictable Stress.

Published in:

Frontiers in Cellular Neuroscience, 2021, v. 15, p. 1, doi. 10.3389/fncel.2021.750373

By:

Yan, Ling;
Jayaram, Mohan;
Chithanathan, Keerthana;
Zharkovsky, Alexander;
Tian, Li

Publication type:

Article

A Peptide Motif Covering Splice Site B in Neuroligin-1 Binds to Aβ and Acts as a Neprilysin Inhibitor.

Published in:

Molecular Neurobiology, 2025, v. 62, n. 3, p. 3244, doi. 10.1007/s12035-024-04475-z

By:

Dietz, Lene T.;
Põld, Katrin;
Györffy, Balázs A.;
Zharkovsky, Alexander;
Sørensen, Jakob B.;
Pankratova, Stanislava;
Dmytriyeva, Oksana

Publication type:

Article

Loss of mitochondrial membrane potential is associated with increase in mitochondrial volume: Physiological role in neurones.

Published in:

Journal of Cellular Physiology, 2006, v. 206, n. 2, p. 347, doi. 10.1002/jcp.20476

By:

Safiulina, Dzhamilja;
Veksler, Vladimir;
Zharkovsky, Alexander;
Kaasik, Allen

Publication type:

Article

Potential drug interactions with statins: Estonian register-based study.

Published in:

Open Medicine, 2015, v. 10, n. 1, p. -1, doi. 10.1515/med-2015-0038

By:

Gavronski, Maia;
Volmer, Daisy;
Hartikainen, Sirpa;
Zharkovsky, Alexander

Publication type:

Article

Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice.

Published in:

European Journal of Neuroscience, 2011, v. 33, n. 1, p. 161, doi. 10.1111/j.1460-9568.2010.07485.x

By:

Procaccini, Chiara;
Aitta‐aho, Teemu;
Jaako‐Movits, Külli;
Zharkovsky, Alexander;
Panhelainen, Anne;
Sprengel, Rolf;
Linden, Anni‐Maija;
Korpi, Esa R.

Publication type:

Article

Depression-like behaviour in neural cell adhesion molecule (NCAM)-deficient mice and its reversal by an NCAM-derived peptide, FGL.

Published in:

European Journal of Neuroscience, 2008, v. 28, n. 8, p. 1618, doi. 10.1111/j.1460-9568.2008.06471.x

By:

Aonurm‐Helm, Anu;
Jurgenson, Monika;
Zharkovsky, Tamara;
Sonn, Katrin;
Berezin, Vladimir;
Bock, Elisabeth;
Zharkovsky, Alexander

Publication type:

Article

Impaired fear memory and decreased hippocampal neurogenesis following olfactory bulbectomy in rats.

Published in:

European Journal of Neuroscience, 2005, v. 22, n. 11, p. 2871, doi. 10.1111/j.1460-9568.2005.04481.x

By:

Jaako‐Movits, Külli;
Zharkovsky, Alexander

Publication type:

Article

Up-regulation of lysosomal cathepsin L and autophagy during neuronal death induced by reduced serum and potassium.

Published in:

European Journal of Neuroscience, 2005, v. 22, n. 5, p. 1023, doi. 10.1111/j.1460-9568.2005.04279.x

By:

Kaasik, Allen;
Rikk, Tiina;
Piirsoo, Andres;
Zharkovsky, Tamara;
Zharkovsky, Alexander

Publication type:

Article

Replenished microglia partially rescue schizophrenia-related stress response.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 01, doi. 10.3389/fncel.2023.1254923

By:

Ling Yan;
Fang-Ling Xuan;
Song Chen;
Mengzhuang Gou;
Wenjin Chen;
Yanli Li;
Zhiren Wang;
Leilei Wang;
Ting Xie;
Fengmei Fan;
Zharkovsky, Alexander;
Yunlong Tan;
Li Tian

Publication type:

Article

Enhanced Cognition and Neurogenesis in miR-146b Deficient Mice.

Published in:

Cells (2073-4409), 2022, v. 11, n. 13, p. N.PAG, doi. 10.3390/cells11132002

By:

Chithanathan, Keerthana;
Somelar, Kelli;
Jürgenson, Monika;
Žarkovskaja, Tamara;
Periyasamy, Kapilraj;
Yan, Ling;
Magilnick, Nathaniel;
Boldin, Mark P.;
Rebane, Ana;
Tian, Li;
Zharkovsky, Alexander

Publication type:

Article

Elocalcitol, a fluorinated vitamin D derivative, prevents high-fat diet-induced obesity via SCAP downregulation and miR-146a-associated mechanisms.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2024.1505729

By:

Jürgenson, Monika;
Chithanathan, Keerthana;
Orav, Aivar;
Jaako, Külli;
Viil, Janeli;
Guha, Mithu;
Kask, Kalev;
Zharkovsky, Alexander

Publication type:

Article

'Unpredictable chronic mild stress does not exacerbate memory impairment or altered neuronal and glial plasticity in the hippocampus of middle‐aged vitamin D deficient mice'.

Published in:

European Journal of Neuroscience, 2024, v. 59, n. 7, p. 1696, doi. 10.1111/ejn.16256

By:

Somelar‐Duracz, Kelli;
Jürgenson, Monika;
Viil, Janeli;
Zharkovsky, Alexander;
Jaako, Külli

Publication type:

Article

Effects of the drug combination memantine and melatonin on impaired memory and brain neuronal deficits in an amyloid‐predominant mouse model of Alzheimer's disease.

Published in:

Journal of Pharmacy & Pharmacology, 2019, v. 71, n. 11, p. 1695, doi. 10.1111/jphp.13165

By:

Jürgenson, Monika;
Zharkovskaja, Tamara;
Noortoots, Aveli;
Morozova, Margarita;
Beniashvili, Allan;
Zapolski, Max;
Zharkovsky, Alexander

Publication type:

Article

Developmental lead exposure impairs contextual fear conditioning and reduces adult hippocampal neurogenesis in the rat brain

Published in:

International Journal of Developmental Neuroscience, 2005, v. 23, n. 7, p. 627, doi. 10.1016/j.ijdevneu.2005.07.005

By:

Jaako-Movits, Külli;
Zharkovsky, Tamara;
Romantchik, Olga;
Jurgenson, Monika;
Merisalu, Eda;
Heidmets, Lenne-Triin;
Zharkovsky, Alexander

Publication type:

Article

Paradoxical attenuation of neuroinflammatory response upon LPS challenge in miR-146b deficient mice.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.996415

By:

Chithanathan, Keerthana;
Jürgenson, Monika;
Guha, Mithu;
Ling Yan;
Žarkovskaja, Tamara;
Pook, Martin;
Magilnick, Nathaniel;
Boldin, Mark P.;
Rebane, Ana;
Li Tian;
Zharkovsky, Alexander

Publication type:

Article

Glial receptor PLXNB2 regulates schizophrenia-related stress perception via the amygdala.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1005067

By:

Fang-Ling Xuan;
Ling Yan;
Yanli Li;
Fengmei Fan;
Hu Deng;
Mengzhuang Gou;
Chithanathan, Keerthana;
Heinla, Indrek;
Liang Yuan;
Seppa, Kadri;
Zharkovsky, Alexander;
Kalda, Anti;
Hong, L. Elliot;
Guo-Fu Hu;
Yunlong Tan;
Li Tian

Publication type:

Article

Dehydroepiandrosterone Inhibits Complex I of the Mitochondrial Respiratory Chain and is Neurotoxic In Vitro and In Vivo at High Concentrations.

Published in:

Toxicological Sciences, 2006, v. 93, n. 2, p. 348, doi. 10.1093/toxsci/kfl064

By:

Safiulina, Dzhamilja;
Peet, Nadezhda;
Seppet, Enn;
Zharkovsky, Alexander;
Kaasik, Allen

Publication type:

Article

The role of DNA methyltransferase activity in cocaine treatment and withdrawal in the nucleus accumbens of mice.

Published in:

2020

By:

Urb, Mari;
Niinep, Kerly;
Matsalu, Terje;
Kipper, Karin;
Herodes, Koit;
Zharkovsky, Alexander;
Timmusk, Tõnis;
Anier, Kaili;
Kalda, Anti

Publication type:

journal article

Schizophrenia-like phenotype of polysialyltransferase ST8SIA2-deficient mice.

Published in:

Brain Structure & Function, 2015, v. 220, n. 1, p. 71, doi. 10.1007/s00429-013-0638-z

By:

Kröcher, Tim;
Malinovskaja, Kristina;
Jürgenson, Monika;
Aonurm-Helm, Anu;
Zharkovskaya, Tamara;
Kalda, Anti;
Röckle, Iris;
Schiff, Miriam;
Weinhold, Birgit;
Gerardy-Schahn, Rita;
Hildebrandt, Herbert;
Zharkovsky, Alexander

Publication type:

Article

Seizures, Ataxia, and Neuronal Loss in Cystatin B Heterozygous Mice.

Published in:

Epilepsia (Series 4), 2007, v. 48, n. 4, p. 752, doi. 10.1111/j.1528-1167.2007.00985.x

By:

Kaasik, Allen;
Kuum, Malle;
Aonurm, Anu;
Kalda, Anti;
Vaarmann, Annika;
Zharkovsky, Alexander

Publication type:

Article

Altered Tryptophan Metabolism in the Brain of Cystatin B-Deficient Mice: A Model System for Progressive Myoclonus Epilepsy.

Published in:

Epilepsia (Series 4), 2006, v. 47, n. 10, p. 1650, doi. 10.1111/j.1528-1167.2006.00638.x

By:

Vaarmann, Annika;
Kaasik, Allen;
Zharkovsky, Alexander

Publication type:

Article

Elocalcitol mitigates high-fat diet-induced microglial senescence via miR-146a modulation.

Published in:

Immunity & Ageing, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12979-024-00485-6

By:

Chithanathan, Keerthana;
Jürgenson, Monika;
Ducena, Katrina;
Remm, Anu;
Kask, Kalev;
Rebane, Ana;
Tian, Li;
Zharkovsky, Alexander

Publication type:

Article