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Hypothalamic insulin signaling is required for inhibition of glucose production.
Published in:
Nature Medicine, 2002, v. 8, n. 12, p. 1376, doi. 10.1038/nm1202-798
By:
- Obici, Silvana;
- Zhang, Bei B.;
- Karkanias, George;
- Rossetti, Luciano
Publication type:
Article
Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity.
Published in:
Nature Medicine, 2002, v. 8, n. 2, p. 179, doi. 10.1038/nm0202-179
By:
- Air, Ellen L.;
- Strowski, Mathias Z.;
- Benoit, Stephen C.;
- Conarello, Stacey L.;
- Salituro, Gino M.;
- Guan, Xiao-Ming;
- Liu, Kun;
- Woods, Stephen C.;
- Zhang, Bei B.
Publication type:
Article
Prevention of obesity in mice by antisense oligonucleotide inhibitors of stearoyl-CoA desaturase--1.
Published in:
Journal of Clinical Investigation, 2005, v. 115, n. 4, p. 1030, doi. 10.1172/JCI200523962
By:
- Jiang, Guoqiang;
- Li, Zhihua;
- Liu, Franklin;
- Ellsworth, Kenneth;
- Dallas-Yang, Qing;
- Wu, Margaret;
- Ronan, John;
- Esau, Christine;
- Murphy, Cain;
- Szalkowski, Deborah;
- Bergeron, Raynald;
- Doebber, Thomas;
- Zhang, Bei B.
Publication type:
Article
A Model Selection Approach for Expression Quantitative Trait Loci (eQTL) Mapping.
Published in:
Genetics, 2011, v. 187, n. 2, p. 611, doi. 10.1534/genetics.110.122796
By:
- Ping Wang;
- Dawson, John A.;
- Keller, Mark P.;
- Yandell, Brian S.;
- Thornberry, Nancy A.;
- Zhang, Bei B.;
- I-Ming Wang;
- Schadt, Eric E.;
- Attie, Alan D.;
- Kendziorski, C.
Publication type:
Article
CHAC1 inactivation is effective to preserve muscle glutathione but is insufficient to protect against muscle wasting in cachexia.
Published in:
PLoS ONE, 2023, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0283806
By:
- Li, Junjie;
- Lu, Mingjian;
- Ahn, Youngwook;
- Cao, Kevin;
- Pinkus, Cynthia A.;
- Stansfield, John C.;
- Wu, Zhidan;
- Zhang, Bei B.
Publication type:
Article
Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.
Published in:
Nature Medicine, 2011, v. 17, n. 1, p. 55, doi. 10.1038/nm.2277
By:
- Holland, William L.;
- Miller, Russell A.;
- Zhao V. Wang;
- Kai Sun;
- Barth, Brian M.;
- Bui, Hai H.;
- Davis, Kathryn E.;
- Bikman, Benjamin T.;
- Halberg, Nils;
- Rutkowski, Joseph M.;
- Wade, Mark R.;
- Tenorio, Vincent M.;
- Ming-Shang Kuo;
- Brozinick, Joseph T.;
- Bei B. Zhang;
- Birnbaum, Morris J.;
- Summers, Scott A.;
- Scherer, Philipp E.
Publication type:
Article
Anti-Diabetic Efficacy and Impact on Amino Acid Metabolism of GRA1, a Novel Small-Molecule Glucagon Receptor Antagonist.
Published in:
PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0049572
By:
- Mu, James;
- Qureshi, Sajjad A.;
- Brady, Edward J.;
- Muise, Eric S.;
- Candelore, Mari Rios;
- Guoqiang Jiang;
- Zhihua Li;
- Wu, Margaret S.;
- Xiaodong Yang;
- Qing Dallas-Yang;
- Miller, Corey;
- Yusheng Xiong;
- Langdon, Ronald B.;
- Parmee, Emma R.;
- Zhang, Bei B.
Publication type:
Article
A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis.
Published in:
PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036384
By:
- Ruojing Yang;
- Lacson, Raul G.;
- Castriota, Gino;
- Zhang, Xiaohua D.;
- Yaping Liu;
- Wenqing Zhao;
- Einstein, Monica;
- Camargo, Luiz Miguel;
- Qureshi, Sajjad;
- Wong, Kenny K.;
- Zhang, Bei B.;
- Ferrer, Marc;
- Berger, Joel P.
Publication type:
Article
Relationship among Brain and Blood Glucose Levels and Spontaneous and Glucoprivic Feeding.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 21, p. 7015, doi. 10.1523/JNEUROSCI.0334-09.2009
By:
- Dunn-Meynell, Ambrose A.;
- Sanders, Nicole M.;
- Compton, Douglas;
- Becker, Thomas C.;
- Eiki, Jun-ichi;
- Zhang, Bei B.;
- Levin, Barry E.
Publication type:
Article
PANIC-ATTAC: a mouse model for inducible and reversible beta-cell ablation.
Published in:
2008
By:
- Wang ZV;
- Mu J;
- Schraw TD;
- Gautron L;
- Elmquist JK;
- Zhang BB;
- Brownlee M;
- Scherer PE;
- Wang, Zhao V;
- Mu, James;
- Schraw, Todd D;
- Gautron, Laurent;
- Elmquist, Joel K;
- Zhang, Bei B;
- Brownlee, Michael;
- Scherer, Philipp E
Publication type:
journal article
PANIC-ATTAC: A Mouse Model for Inducible and Reversible β-Cell Ablation.
Published in:
Diabetes, 2008, v. 57, n. 8, p. 2137, doi. 10.2337/db07-1631
By:
- Wang, Zhao V.;
- Mu, James;
- Schraw, Todd D.;
- Gautron, Laurent;
- Elmquist, Joel K.;
- Zhang, Bei B.;
- Brownlee, Michael;
- Scherer, Philipp E.
Publication type:
Article
Malonyl CoenzymeA Decarboxylase Regulates Lipid and Glucose Metabolism in Human Skeletal Muscle.
Published in:
Diabetes, 2008, v. 57, n. 6, p. 1508, doi. 10.2337/db07-0583
By:
- Bouzakri, Karim;
- Austin, Reginald;
- Rune, Anna;
- Lassman, Michael E.;
- Garcia-Roves, Pablo M.;
- Berger, Joel P.;
- Krook, Anna;
- Chibalin, Alexander V.;
- Zhang, Bei B.;
- Zierath, Juleen R.
Publication type:
Article
Ventromedial Hypothalamic Glucokinase Is an Important Mediator of the Counterregulatory Response to Insulin-Induced Hypoglycemia.
Published in:
Diabetes, 2008, v. 57, n. 5, p. 1371, doi. 10.2337/db07-1755
By:
- Levin, Barry E.;
- Becker, Thomas C.;
- Eiki, Jun-ichi;
- Zhang, Bei B.;
- Dunn-Meynell, Ambrose A.
Publication type:
Article
Sitagliptin Improves Glycemic Control and Restores Islet Cell Mass and Function in a Rodent Model of Type 2 Diabetes.
Published in:
Diabetes, 2007, v. 56, p. A550
By:
- Mu, James;
- Woods, John;
- Yun-Ping Zhou;
- Petrov, Aleksandr;
- Zhihuali;
- Yue Feng;
- Zycband, Emanuel;
- Eiermann, George J.;
- Howard, Andrew;
- Cai Li;
- Thornberry, Nancy A.;
- Zhang, Bei B.
Publication type:
Article
Microarray Profiling Demonstrates Important Similarities, and Differences, Between the Liver and Adipose Tissue Signatures of Adiponectin and PPARγ Agonists.
Published in:
Diabetes, 2007, v. 56, p. A285
By:
- Muise, Eric S.;
- Shang, Jin;
- Yejun Tan;
- Nawrocki, Andrea R.;
- Ja-young Kim;
- Khan, Tayeba;
- Chabin, Renee;
- Wong, Kenny;
- Thompson, John R.;
- Zhang, Bei B.;
- Scherer, Philipp E.;
- Berger, Joel P.
Publication type:
Article
Deletion of Glucagon Receptor in Mice Results in Altered Lipid Metabolism and Body Weight Regulation.
Published in:
Diabetes, 2007, v. 56, p. A285
By:
- Mu, James;
- Muise, Eric;
- Tan, Eugene;
- Zhihua Li;
- Azzolina, Barbara;
- El-Sherbeini, Mohamed;
- Wong, Kenny;
- Li, Cai;
- Thompson, John;
- Berger, Joel P.;
- Charron, Maureen J.;
- Zhang, Bei B.
Publication type:
Article
Chronic Inhibition of Dipeptidyl Peptidase-4 With a Sitagliptin Analog Preserves Pancreatic ß-Cell Mass and Function in a Rodent Model of Type 2 Diabetes.
Published in:
Diabetes, 2006, v. 55, n. 6, p. 1695, doi. 10.2337/db05-1602
By:
- Mu, James;
- Woods, John;
- Zhou, Yun-Ping;
- Roy, Ranabir Sinha;
- Li, Zhihua;
- Zycband, Emanuel;
- Feng, Yue;
- Zhu, Lan;
- Li, Cai;
- Howard, Andrew D.;
- Moller, David E.;
- Thornberry, Nancy A.;
- Zhang, Bei B.
Publication type:
Article
Glucokinase Is a Critical Regulator of Ventromedial Hypothalamic Neuronal Glucosensing.
Published in:
Diabetes, 2006, v. 55, n. 2, p. 412, doi. 10.2337/diabetes.55.02.06.db05-1229
By:
- Kang, Ling;
- Dunn-Meynell, Ambrose A.;
- Routh, Vanessa H.;
- Gaspers, Larry D.;
- Nagata, Yasufumi;
- Nishimura, Teruyuki;
- Eikis, Junichi;
- Zhang, Bei B.;
- Levin, Barry E.
Publication type:
Article
A novel glucagon receptor antagonist inhibits glucagon-mediated biological effects.
Published in:
2004
By:
- Qureshi, Sajjad A.;
- Candelore, Mari Rios;
- Xie, Dan;
- Yang, Xiaodong;
- Tota, Laurie M.;
- Ding, Victor D.-H.;
- Li, Zhihua;
- Bansal, Alka;
- Miller, Corin;
- Cohen, Sheila M.;
- Jiang, Guoqiang;
- Brady, Ed;
- Saperstein, Richard;
- Duffy, Joseph L.;
- Tata, James R.;
- Chapman, Kevin T.;
- Moller, David E.;
- Zhang, Bei B.;
- Rios Candelore, Mari
Publication type:
journal article
Potentiation of insulin signaling in tissues of Zucker obese rats after acute and long-term treatment with PPARgamma agonists.
Published in:
2002
By:
- Guoqiang Jiang;
- Jiang, Guoqiang;
- Dallas-Yang, Qing;
- Qing Dallas-Yang;
- Zhihua Li;
- Li, Zhihua;
- Szalkowski, Deborah;
- Liu, Franklin;
- Xiaolan Shen;
- Shen, Xiaolan;
- Wu, Margaret;
- Gaochao Zhou;
- Zhou, Gaochao;
- Doebber, Thomas;
- Berger, Joel;
- Moller, David E.;
- Zhang, Bei B.
Publication type:
journal article
Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells.
Published in:
2002
By:
- Roper, Michael G.;
- Wei-jun Qian;
- Zhang, Bei B.;
- Kulkarni, Rohit N.;
- Kahn, C. Ronald;
- Kennedy, Robert T.;
- Qian, Wei-jun
Publication type:
journal article
Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells.
Published in:
2001
By:
- Li, Ming;
- Youngren, Jack F.;
- Manchem, Vara Prasad;
- Kozlowski, Michael;
- Zhang, Bei B.;
- Maddux, Betty A.;
- Goldfine, Ira D.;
- Li, M;
- Youngren, J F;
- Manchem, V P;
- Kozlowski, M;
- Zhang, B B;
- Maddux, B A;
- Goldfine, I D
Publication type:
journal article
Pharmacological inhibition of IRAK4 kinase activity does not prevent cachexia in mice with pancreatic cancer.
Published in:
JCSM Rapid Communications, 2023, v. 6, n. 2, p. 122, doi. 10.1002/rco2.85
By:
- Qiao, Shuxi;
- LaViolette, Brianna;
- Paulhus, Brianna LaCarubba;
- Li, Xiangping;
- Litchfield, John;
- Li, Zhenhong;
- Stansfield, John C.;
- Gieseck, Richard L.;
- Zhang, Bei B.;
- Breen, Danna M.
Publication type:
Article
1922-P: Branched-Chain Ketoacid Dehydrogenase Kinase Inhibition Acutely Improves Glycemia and Alters the Response to Feeding in Mice.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1922-P
By:
- BOLLINGER, ELIZA;
- SIDDALL, CHARLES PARKER;
- GREIZER, TIMOTHY;
- LIBERA, JENNA L.;
- HARIRI, GHAZAL;
- PASHOS, EVANTHIA E.;
- SHIPSTONE, ARUN;
- HADJIPANAYIS, ANGELA;
- SUN, ZHONGYUAN;
- XING, GANG;
- CLASQUIN, MICHELLE F.;
- ZHANG, BEI B.;
- MILLER, RUSSELL A.;
- ROTH FLACH, RACHEL
Publication type:
Article
1901-P: CK1 δ/ε Inhibitor PF-05006739 Ameliorates Hepatic Steatosis and Hyperinsulinemia in Dio Mice.
Published in:
Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-1901-P
By:
- PELOQUIN, MATTHEW;
- LITCHFIELD, JOHN;
- ZHANG, BEI B.;
- CHANG, CHENG;
- MILLER, RUSSELL A.;
- BERNARDO, BARBARA;
- LUTHRA, SUMAN;
- CORTES, CHRISTIAN;
- LI II, XIANGPING;
- ZOU, CHANG J.
Publication type:
Article
Hepatic GALE Regulates Whole-Body Glucose Homeostasis by Modulating Expression.
Published in:
2017
By:
- Yi Zhu;
- Shangang Zhao;
- Yingfeng Deng;
- Gordillo, Ruth;
- Ghaben, Alexandra L.;
- Mengle Shao;
- Fang Zhang;
- Ping Xu;
- Yang Li;
- Huachuan Cao;
- Zagnitko, Olga;
- Scott, David A.;
- Gupta, Rana K.;
- Chao Xing;
- Bei B. Zhang;
- Hua V. Lin;
- Scherer, Philipp E.;
- Zhu, Yi;
- Zhao, Shangang;
- Deng, Yingfeng
Publication type:
journal article
FGF21 Analogs of Sustained Action Enabled by Orthogonal Biosynthesis Demonstrate Enhanced Antidiabetic Pharmacology in Rodents.
Published in:
Diabetes, 2012, v. 61, n. 2, p. 505, doi. 10.2337/db11-0838
By:
- Mu, James;
- Pinkstaff, Jason;
- Zhihua Li;
- Skidmore, Lillian;
- Nina Li;
- Myler, Heather;
- Dallas-Yang, Qing;
- Putnam, Anna-Maria;
- Jun Yao;
- Bussell, Stuart;
- Wu, Margaret;
- Norman, Thea C.;
- Rodriguez, Carlos G.;
- Kimmel, Bruce;
- Metzger, Joseph M.;
- Manibusan, Anthony;
- Lee, Darin;
- Zaller, Dennis M.;
- Zhang, Bei B.;
- DiMarchi, Richard D.
Publication type:
Article

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