Works by Zdarova Karasova, Jana

Results: 66
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    The New Acetylcholinesterase Inhibitors PC‐37 and PC‐48 (7‐Methoxytacrine‐Donepezil‐Like Compounds): Characterization of Their Metabolites in Human Liver Microsomes, Pharmacokinetics and <italic>In Vivo</italic> Formation of the Major Metabolites in Rats

    Published in:
    Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 4, p. 373, doi. 10.1111/bcpt.12922
    By:
    • Zdarova Karasova, Jana;
    • Mzik, Martin;
    • Hroch, Milos;
    • Korabecny, Jan;
    • Nepovimova, Eugenie;
    • Vorisek, Viktor;
    • Palicka, Vladimir;
    • Kuca, Kamil
    Publication type:
    Article
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    A-series agent A-234: initial in vitro and in vivo characterization.

    Published in:
    Archives of Toxicology, 2024, v. 98, n. 4, p. 1135, doi. 10.1007/s00204-024-03689-3
    By:
    • Hrabinova, Martina;
    • Pejchal, Jaroslav;
    • Hepnarova, Vendula;
    • Muckova, Lubica;
    • Junova, Lucie;
    • Opravil, Jakub;
    • Zdarova Karasova, Jana;
    • Rozsypal, Tomas;
    • Dlabkova, Alzbeta;
    • Rehulkova, Helena;
    • Kucera, Tomas;
    • Vecera, Zbyněk;
    • Caisberger, Filip;
    • Schmidt, Monika;
    • Soukup, Ondrej;
    • Jun, Daniel
    Publication type:
    Article
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    Development of versatile and potent monoquaternary reactivators of acetylcholinesterase.

    Published in:
    Archives of Toxicology, 2021, v. 95, n. 3, p. 985, doi. 10.1007/s00204-021-02981-w
    By:
    • Gorecki, Lukas;
    • Hepnarova, Vendula;
    • Karasova, Jana Zdarova;
    • Hrabinova, Martina;
    • Courageux, Charlotte;
    • Dias, José;
    • Kucera, Tomas;
    • Kobrlova, Tereza;
    • Muckova, Lubica;
    • Prchal, Lukas;
    • Malinak, David;
    • Jun, Daniel;
    • Musilek, Kamil;
    • Worek, Franz;
    • Nachon, Florian;
    • Soukup, Ondrej;
    • Korabecny, Jan
    Publication type:
    Article
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    Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

    Published in:
    Angewandte Chemie International Edition, 2025, v. 64, n. 6, p. 1, doi. 10.1002/anie.202420510
    By:
    • Panek, Dawid;
    • Pasieka, Anna;
    • Jończyk, Jakub;
    • Gawlińska, Milena;
    • Zaręba, Paula;
    • Siwek, Agata;
    • Wolak, Małgorzata;
    • Mordyl, Barbara;
    • Głuch‐Lutwin, Monika;
    • Latacz, Gniewomir;
    • Brazzolotto, Xavier;
    • Chantegreil, Fabien;
    • Nachon, Florian;
    • Zdarova Karasova, Jana;
    • Pejchal, Jaroslav;
    • Mzik, Martin;
    • Sestak, Vit;
    • Prchal, Lukas;
    • Odvarkova, Jitka;
    • Soukup, Ondrej
    Publication type:
    Article
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    Methylacridinium and its Cholinergic Properties.

    Published in:
    Neurotoxicity Research, 2009, v. 16, n. 4, p. 372, doi. 10.1007/s12640-009-9071-8
    By:
    • Soukup, Ondrej;
    • Proska, Jan;
    • Binder, Jiri;
    • Karasova, Jana Zdarova;
    • Tobin, Gunnar;
    • Jun, Daniel;
    • Marek, Jan;
    • Musílek, Kamil;
    • Fusek, Josef;
    • Kuca, Kamil
    Publication type:
    Article
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    Multifunctional, Fluorene‐Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.

    Published in:
    Angewandte Chemie, 2025, v. 137, n. 6, p. 1, doi. 10.1002/ange.202420510
    By:
    • Panek, Dawid;
    • Pasieka, Anna;
    • Jończyk, Jakub;
    • Gawlińska, Milena;
    • Zaręba, Paula;
    • Siwek, Agata;
    • Wolak, Małgorzata;
    • Mordyl, Barbara;
    • Głuch‐Lutwin, Monika;
    • Latacz, Gniewomir;
    • Brazzolotto, Xavier;
    • Chantegreil, Fabien;
    • Nachon, Florian;
    • Zdarova Karasova, Jana;
    • Pejchal, Jaroslav;
    • Mzik, Martin;
    • Sestak, Vit;
    • Prchal, Lukas;
    • Odvarkova, Jitka;
    • Soukup, Ondrej
    Publication type:
    Article
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    The Impact of Dextran Sodium Sulfate-Induced Gastrointestinal Injury on the Pharmacokinetic Parameters of Donepezil and Its Active Metabolite 6- O -desmethyldonepezil, and Gastric Myoelectric Activity in Experimental Pigs.

    Published in:
    Molecules, 2021, v. 26, n. 8, p. 2160, doi. 10.3390/molecules26082160
    By:
    • Bures, Jan;
    • Tacheci, Ilja;
    • Kvetina, Jaroslav;
    • Radochova, Vera;
    • Prchal, Lukas;
    • Kohoutova, Darina;
    • Valis, Martin;
    • Novak, Martin;
    • Dolezal, Rafael;
    • Kopacova, Marcela;
    • Rejchrt, Stanislav;
    • Sestak, Vit;
    • Knoblochova, Veronika;
    • Peterova, Eva;
    • Zdarova Karasova, Jana
    Publication type:
    Article
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    Determination of Hypericin in Hypericum perforatum (St. John's Wort) Using Classical C18 and Pentafluorophenyl Stationary Phases: Contribution of Pi–Pi Interactions to High-Performance Liquid Chromatography (HPLC).

    Published in:
    Analytical Letters, 2019, v. 52, n. 11, p. 1788, doi. 10.1080/00032719.2019.1571076
    By:
    • Doležal, Rafael;
    • Houdková, Iva;
    • Kalász, Huba;
    • Andrýs, Rudolf;
    • Novák, Martin;
    • Maltsevskaya, Nadezhda V.;
    • Karásková, Natálie;
    • Kolář, Karel;
    • Novotná, Eva;
    • Kuča, Kamil;
    • Žďárová Karasová, Jana
    Publication type:
    Article
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