Works by Zapatka, Marc

Results: 57
    1

    Longitudinal omics data and preclinical treatment suggest the proteasome inhibitor carfilzomib as therapy for ibrutinib-resistant CLL.

    Published in:
    Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-56318-7
    By:
    • Arseni, Lavinia;
    • Sigismondo, Gianluca;
    • Yazdanparast, Haniyeh;
    • Hermansen, Johanne U.;
    • Mack, Norman;
    • Ohl, Sibylle;
    • Kalter, Verena;
    • Iskar, Murat;
    • Kalxdorf, Mathias;
    • Friedel, Dennis;
    • Rettel, Mandy;
    • Paul, Yashna;
    • Ringshausen, Ingo;
    • Eldering, Eric;
    • Dubois, Julie;
    • Kater, Arnon P.;
    • Zapatka, Marc;
    • Roessner, Philipp M.;
    • Tausch, Eugen;
    • Stilgenbauer, Stephan
    Publication type:
    Article
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    Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia.

    Published in:
    PLoS Genetics, 2014, v. 10, n. 6, p. 1, doi. 10.1371/journal.pgen.1004345
    By:
    • Juraeva, Dilafruz;
    • Haenisch, Britta;
    • Zapatka, Marc;
    • Frank, Josef;
    • Witt, Stephanie H.;
    • Mühleisen, Thomas W.;
    • Treutlein, Jens;
    • Strohmaier, Jana;
    • Meier, Sandra;
    • Degenhardt, Franziska;
    • Giegling, Ina;
    • Ripke, Stephan;
    • Leber, Markus;
    • Lange, Christoph;
    • Schulze, Thomas G.;
    • Mössner, Rainald;
    • Nenadic, Igor;
    • Sauer, Heinrich;
    • Rujescu, Dan;
    • Maier, Wolfgang
    Publication type:
    Article
    9

    Exploration of whole genome and transcriptome sequencing data lacks evidence for oncogenic viral elements to drive the pathogenesis of T-cell prolymphocytic leukemia.

    Published in:
    Leukemia & Lymphoma, 2022, v. 63, n. 13, p. 3253, doi. 10.1080/10428194.2022.2116933
    By:
    • Patil, Paurnima;
    • Toprak, Umut H.;
    • Seufert, Julian;
    • Braun, Till;
    • Bernhart, Stephan H.;
    • Wiehle, Laura;
    • Müller, Annika;
    • Schlesner, Matthias;
    • Herling, Marco;
    • Lichter, Peter;
    • Stilgenbauer, Stephan;
    • Siebert, Reiner;
    • Zapatka, Marc
    Publication type:
    Article
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    Carbon ion radiotherapy eradicates medulloblastomas with chromothripsis in an orthotopic Li-Fraumeni patient-derived mouse model.

    Published in:
    Neuro-Oncology, 2021, v. 23, n. 12, p. 2028, doi. 10.1093/neuonc/noab127
    By:
    • Simovic, Milena;
    • Bolkestein, Michiel;
    • Moustafa, Mahmoud;
    • Wong, John K L;
    • Körber, Verena;
    • Benedetto, Sarah;
    • Khalid, Umar;
    • Schreiber, Hannah Sophia;
    • Jugold, Manfred;
    • Korshunov, Andrey;
    • Hübschmann, Daniel;
    • Mack, Norman;
    • Brons, Stephan;
    • Wei, Pei-Chi;
    • Breckwoldt, Michael O;
    • Heiland, Sabine;
    • Bendszus, Martin;
    • Debus, Jürgen;
    • Höfer, Thomas;
    • Zapatka, Marc
    Publication type:
    Article
    12
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    Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity.

    Published in:
    Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31866-4
    By:
    • Möhrmann, Lino;
    • Werner, Maximilian;
    • Oleś, Małgorzata;
    • Mock, Andreas;
    • Uhrig, Sebastian;
    • Jahn, Arne;
    • Kreutzfeldt, Simon;
    • Fröhlich, Martina;
    • Hutter, Barbara;
    • Paramasivam, Nagarajan;
    • Richter, Daniela;
    • Beck, Katja;
    • Winter, Ulrike;
    • Pfütze, Katrin;
    • Heilig, Christoph E.;
    • Teleanu, Veronica;
    • Lipka, Daniel B.;
    • Zapatka, Marc;
    • Hanf, Dorothea;
    • List, Catrin
    Publication type:
    Article
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    Breast cancer: a candidate gene approach across the estrogen metabolic pathway.

    Published in:
    Breast Cancer Research & Treatment, 2008, v. 108, n. 1, p. 137
    By:
    • Ute Hamann;
    • Falk Schubert;
    • Marc Zapatka;
    • Christiane Pierl;
    • Sylvia Rabstein;
    • Tina Mueller;
    • Katja Ickstadt;
    • Michael Gilbert;
    • Yon-Dschun Ko;
    • Christian Baisch;
    • Beate Pesch;
    • Volker Harth;
    • Hermann Bolt;
    • Caren Vollmert;
    • Thomas Illig;
    • Roland Eils;
    • Jürgen Dippon
    Publication type:
    Article
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    Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma.

    Published in:
    Cancer Immunology, Immunotherapy, 2012, v. 61, n. 11, p. 2091, doi. 10.1007/s00262-012-1266-9
    By:
    • Becker, Jürgen;
    • Andersen, Mads;
    • Hofmeister-Müller, Valeska;
    • Wobser, Marion;
    • Frey, Lidia;
    • Sandig, Christiane;
    • Walter, Steffen;
    • Singh-Jasuja, Harpreet;
    • Kämpgen, Eckhart;
    • Opitz, Andreas;
    • Zapatka, Marc;
    • Bröcker, Eva-B.;
    • thor Straten, Per;
    • Schrama, David;
    • Ugurel, Selma
    Publication type:
    Article
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    Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling.

    Published in:
    Nature Communications, 2015, v. 6, n. 6, p. 7391, doi. 10.1038/ncomms8391
    By:
    • Zuckermann, Marc;
    • Hovestadt, Volker;
    • Knobbe-Thomsen, Christiane B.;
    • Zapatka, Marc;
    • Northcott, Paul A.;
    • Schramm, Kathrin;
    • Belic, Jelena;
    • Jones, David T. W.;
    • Tschida, Barbara;
    • Moriarity, Branden;
    • Largaespada, David;
    • Roussel, Martine F.;
    • Korshunov, Andrey;
    • Reifenberger, Guido;
    • Pfister, Stefan M.;
    • Lichter, Peter;
    • Kawauchi, Daisuke;
    • Gronych, Jan
    Publication type:
    Article
    26

    Robust molecular subgrouping and copy-number profiling of medulloblastoma from small amounts of archival tumour material using high-density DNA methylation arrays.

    Published in:
    2013
    By:
    • Hovestadt, Volker;
    • Remke, Marc;
    • Kool, Marcel;
    • Pietsch, Torsten;
    • Northcott, Paul;
    • Fischer, Roger;
    • Cavalli, Florence;
    • Ramaswamy, Vijay;
    • Zapatka, Marc;
    • Reifenberger, Guido;
    • Rutkowski, Stefan;
    • Schick, Matthias;
    • Bewerunge-Hudler, Melanie;
    • Korshunov, Andrey;
    • Lichter, Peter;
    • Taylor, Michael;
    • Pfister, Stefan;
    • Jones, David
    Publication type:
    Letter
    27

    Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06925-4
    By:
    • Ratnaparkhe, Manasi;
    • Wong, John K. L.;
    • Wei, Pei-Chi;
    • Hlevnjak, Mario;
    • Kolb, Thorsten;
    • Simovic, Milena;
    • Haag, Daniel;
    • Paul, Yashna;
    • Devens, Frauke;
    • Northcott, Paul;
    • Jones, David T. W.;
    • Kool, Marcel;
    • Jauch, Anna;
    • Pastorczak, Agata;
    • Mlynarski, Wojciech;
    • Korshunov, Andrey;
    • Kumar, Rajiv;
    • Downing, Susanna M.;
    • Pfister, Stefan M.;
    • Zapatka, Marc
    Publication type:
    Article
    28

    Integrative genomic and transcriptomic analysis of leiomyosarcoma.

    Published in:
    Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02602-0
    By:
    • Chudasama, Priya;
    • Mughal, Sadaf S.;
    • Sanders, Mathijs A.;
    • Hübschmann, Daniel;
    • Inn Chung;
    • Deeg, Katharina I.;
    • Siao-Han Wong;
    • Rabe, Sophie;
    • Hlevnjak, Mario;
    • Zapatka, Marc;
    • Ernst, Aurélie;
    • Kleinheinz, Kortine;
    • Schlesner, Matthias;
    • Sieverling, Lina;
    • Klink, Barbara;
    • Schröck, Evelin;
    • Hoogenboezem, Remco M.;
    • Kasper, Bernd;
    • Heilig, Christoph E.;
    • Egerer, Gerlinde
    Publication type:
    Article
    29
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    MED12 mutations and NOTCH signalling in chronic lymphocytic leukaemia.

    Published in:
    British Journal of Haematology, 2017, v. 179, n. 3, p. 421, doi. 10.1111/bjh.14869
    By:
    • Wu, Bian;
    • Słabicki, Mikołaj;
    • Sellner, Leopold;
    • Dietrich, Sascha;
    • Liu, Xiyang;
    • Jethwa, Alexander;
    • Hüllein, Jennifer;
    • Walther, Tatjana;
    • Wagner, Lena;
    • Huang, Zhiqin;
    • Zapatka, Marc;
    • Zenz, Thorsten
    Publication type:
    Article
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    Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks.

    Published in:
    Molecular Systems Biology, 2019, v. 15, n. 5, p. N.PAG, doi. 10.15252/msb.20188339
    By:
    • Mallm, Jan‐Philipp;
    • Iskar, Murat;
    • Ishaque, Naveed;
    • Klett, Lara C;
    • Kugler, Sabrina J;
    • Muino, Jose M;
    • Teif, Vladimir B;
    • Poos, Alexandra M;
    • Großmann, Sebastian;
    • Erdel, Fabian;
    • Tavernari, Daniele;
    • Koser, Sandra D;
    • Schumacher, Sabrina;
    • Brors, Benedikt;
    • König, Rainer;
    • Remondini, Daniel;
    • Vingron, Martin;
    • Stilgenbauer, Stephan;
    • Lichter, Peter;
    • Zapatka, Marc
    Publication type:
    Article
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    Tumor-derived exosomes modulate PD-L1 expression in monocytes.

    Published in:
    Science Immunology, 2017, v. 2, n. 13, p. 1, doi. 10.1126/sciimmunol.aah5509
    By:
    • Haderk, Franziska;
    • Schulz, Ralph;
    • Iskar, Murat;
    • Cid, Laura Llaó;
    • Worst, Thomas;
    • Willmund, Karolin V.;
    • Schulz, Angela;
    • Warnken, Uwe;
    • Seiler, Jana;
    • Benner, Axel;
    • Nessling, Michelle;
    • Zenz, Thorsten;
    • Göbel, Maria;
    • Dürig, Jan;
    • Diederichs, Sven;
    • Paggetti, Jérôme;
    • Moussay, Etienne;
    • Stilgenbauer, Stephan;
    • Zapatka, Marc;
    • Lichter, Peter
    Publication type:
    Article
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    Biopsy‐derived organoids in personalised early breast cancer care: Challenges of tumour purity and normal cell overgrowth cap their practical utility.

    Published in:
    International Journal of Cancer, 2025, v. 156, n. 11, p. 2200, doi. 10.1002/ijc.35386
    By:
    • Schwerd‐Kleine, Paul;
    • Würth, Roberto;
    • Cheytan, Tasneem;
    • Michel, Laura;
    • Thewes, Verena;
    • Gutjahr, Ewgenija;
    • Seker‐Cin, Huriye;
    • Kazdal, Daniel;
    • Neuberth, Sarah‐Jane;
    • Thiel, Vera;
    • Schwickert, Jonas;
    • Vorberg, Tim;
    • Wischhusen, Jennifer;
    • Stenzinger, Albrecht;
    • Zapatka, Marc;
    • Lichter, Peter;
    • Schneeweiss, Andreas;
    • Trumpp, Andreas;
    • Sprick, Martin R.
    Publication type:
    Article
    44

    Unraveling most abundant mutational signatures in head and neck cancer.

    Published in:
    International Journal of Cancer, 2021, v. 148, n. 1, p. 115, doi. 10.1002/ijc.33297
    By:
    • Plath, Michaela;
    • Gass, Johanna;
    • Hlevnjak, Mario;
    • Li, Qiaoli;
    • Feng, Bohai;
    • Hostench, Xavier Pastor;
    • Bieg, Matthias;
    • Schroeder, Lea;
    • Holzinger, Dana;
    • Zapatka, Marc;
    • Freier, Kolja;
    • Weichert, Wilko;
    • Hess, Jochen;
    • Zaoui, Karim
    Publication type:
    Article
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    Mismatch Repair Deficiency Drives Durable Complete Remission by Targeting Programmed Death Receptor 1 in a Metastatic Luminal Breast Cancer Patient.

    Published in:
    Breast Care, 2019, v. 14, n. 1, p. 53, doi. 10.1159/000492580
    By:
    • Fremd, Carlo;
    • Hlevnjak, Mario;
    • Zapatka, Marc;
    • Zoernig, Inka;
    • Halama, Niels;
    • Fejzibegovic, Nino;
    • Thewes, Verena;
    • Lichter, Peter;
    • Schirmacher, Peter;
    • Kloor, Matthias;
    • Marmé, Frederik;
    • Schütz, Florian;
    • Kosaloglu, Zeynep;
    • Sinn, Hans Peter;
    • Jäger, Dirk;
    • Schneeweiss, andreas
    Publication type:
    Article
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