Works matching AU Zandstra, Peter W.

Results: 66

Microenvironment-mediated reversion of epiblast stem cells by reactivation of repressed JAK–STAT signaling.

Published in:

Integrative Biology, 2012, v. 4, n. 11, p. 1367, doi. 10.1039/c2ib20098h

By:

Onishi, Kento;
Tonge, Peter D.;
Nagy, Andras;
Zandstra, Peter W.

Publication type:

Article

High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation–associated versus preneurulation-associated fate patterning.

Published in:

PLoS Biology, 2019, v. 17, n. 10, p. 1, doi. 10.1371/journal.pbio.3000081

By:

Tewary, Mukul;
Dziedzicka, Dominika;
Ostblom, Joel;
Prochazka, Laura;
Shakiba, Nika;
Heydari, Tiam;
Aguilar-Hidalgo, Daniel;
Woodford, Curtis;
Piccinini, Elia;
Becerra-Alonso, David;
Vickers, Alice;
Louis, Blaise;
Rahman, Nafees;
Danovi, Davide;
Geens, Mieke;
Watt, Fiona M.;
Zandstra, Peter W.

Publication type:

Article

Process evolution in cell and gene therapy from discovery to commercialization.

Published in:

Canadian Journal of Chemical Engineering, 2021, v. 99, n. 11, p. 2517, doi. 10.1002/cjce.24141

By:

Csaszar, Elizabeth;
Mills, Sara;
Zandstra, Peter W.

Publication type:

Article

Manipulation of Signaling Thresholds in "Engineered Stem Cell Niches" Identifies Design Criteria for Pluripotent Stem Cell Screens.

Published in:

PLoS ONE, 2009, v. 4, n. 7, p. 1, doi. 10.1371/journal.pone.0006438

By:

Peerani, Raheem;
Onishi, Kento;
Mahdavi, Alborz;
Kumacheva, Eugenia;
Zandstra, Peter W.

Publication type:

Article

Reproducible, Ultra High-Throughput Formation of Multicellular Organization from Single Cell Suspension-Derived Human Embryonic Stem Cell Aggregates.

Published in:

PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001565

By:

Ungrin, Mark D.;
Joshi, Chirag;
Nica, Andra;
Bauwens, Céline;
Zandstra, Peter W.

Publication type:

Article

LIF-mediated control of embryonic stem cell self-renewal emerges due to an autoregulatory loop.

Published in:

FASEB Journal, 2007, v. 21, n. 9, p. 2020, doi. 10.1096/fj.06-7852com

By:

Davey, Ryan E.;
Onishi, Kento;
Mahdavi, Alborz;
Zandstra, Peter W.

Publication type:

Article

Intercellular network structure and regulatory motifs in the human hematopoietic system.

Published in:

Molecular Systems Biology, 2014, v. 10, n. 7, p. n/a, doi. 10.15252/msb.20145141

By:

Qiao, Wenlian;
Wang, Weijia;
Laurenti, Elisa;
Turinsky, Andrei L;
Wodak, Shoshana J;
Bader, Gary D;
Dick, John E;
Zandstra, Peter W

Publication type:

Article

Dynamic interaction networks in a hierarchically organized tissue.

Published in:

Molecular Systems Biology, 2010, v. 6, n. 1, p. 1, doi. 10.1038/msb.2010.71

By:

Kirouac, Daniel C;
Ito, Caryn;
Csaszar, Elizabeth;
Roch, Aline;
Yu, Mei;
Sykes, Edward A;
Bader, Gary D;
Zandstra, Peter W

Publication type:

Article

Cell–cell interaction networks regulate blood stem and progenitor cell fate.

Published in:

Molecular Systems Biology, 2009, v. 5, n. 1, p. 293, doi. 10.1038/msb.2009.49

By:

Kirouac, Daniel C;
Madlambayan, Gerard J;
Yu, Mei;
Sykes, Edward A;
Ito, Caryn;
Zandstra, Peter W

Publication type:

Article

Context-explorer: Analysis of spatially organized protein expression in high-throughput screens.

Published in:

PLoS Computational Biology, 2019, v. 15, n. 01, p. 1, doi. 10.1371/journal.pcbi.1006384

By:

Ostblom, Joel;
Nazareth, Emanuel J. P.;
Tewary, Mukul;
Zandstra, Peter W.

Publication type:

Article

Quantitative screening of embryonic stem cell differentiation: Endoderm formation as a model.

Published in:

Biotechnology & Bioengineering, 2004, v. 88, n. 3, p. 287, doi. 10.1002/bit.20242

By:

Chang, Karen H.;
Zandstra, Peter W.

Publication type:

Article

The opportunity of stem cell bioengineering.

Published in:

Biotechnology & Bioengineering, 2004, v. 88, n. 3, p. 263, doi. 10.1002/bit.20303

By:

Zandstra, Peter W.

Publication type:

Article

Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.

Published in:

Biotechnology & Bioengineering, 2002, v. 78, n. 4, p. 442, doi. 10.1002/bit.10220

By:

Dang, Stephen M.;
Kyba, Michael;
Perlingeiro, Rita;
Daley, George Q.;
Zandstra, Peter W.

Publication type:

Article

Multi-objective optimization reveals time- and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development.

Published in:

NPJ Regenerative Medicine, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41536-022-00210-1

By:

Edgar, John M.;
Michaels, Yale S.;
Zandstra, Peter W.

Publication type:

Article

Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells.

Published in:

Molecular Systems Biology, 2022, v. 18, n. 11, p. 1, doi. 10.15252/msb.202110886

By:

Prochazka, Laura;
Michaels, Yale S;
Lau, Charles;
Jones, Ross D;
Siu, Mona;
Yin, Ting;
Wu, Diana;
Jang, Esther;
Vázquez‐Cantú, Mercedes;
Gilbert, Penney M;
Kaul, Himanshu;
Benenson, Yaakov;
Zandstra, Peter W

Publication type:

Article

Modeling signaling‐dependent pluripotency with Boolean logic to predict cell fate transitions.

Published in:

Molecular Systems Biology, 2018, v. 14, n. 1, p. 1, doi. 10.15252/msb.20177952

By:

Yachie‐Kinoshita, Ayako;
Onishi, Kento;
Ostblom, Joel;
Langley, Matthew A.;
Posfai, Eszter;
Rossant, Janet;
Zandstra, Peter W.

Publication type:

Article

Sensitivity Analysis of Intracellular Signaling Pathway Kinetics Predicts Targets for Stem Cell Fate Control.

Published in:

PLoS Computational Biology, 2007, v. 3, n. 7, p. e130, doi. 10.1371/journal.pcbi.0030130

By:

Mahdavi, Alborz;
Davey, Ryan E.;
Bhola, Patrick;
Ting Yin;
Zandstra, Peter W.

Publication type:

Article

Enabling stem cell therapies through synthetic stem cell-niche engineering.

Published in:

2010

By:

Peerani, Raheem;
Zandstra, Peter W.

Publication type:

journal article

Fluorescence activated cell sorting reveals heterogeneous and cell non-autonomous osteoprogenitor differentiation in fetal rat calvaria cell populations.

Published in:

Journal of Cellular Biochemistry, 2003, v. 90, n. 1, p. 109, doi. 10.1002/jcb.10596

By:

Kelly A. Purpura;
Peter W. Zandstra;
Jane E. Aubin

Publication type:

Article

Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform.

Published in:

Scientific Reports, 2016, p. 31951, doi. 10.1038/srep31951

By:

Müller, Eike;
Wang, Weijia;
Qiao, Wenlian;
Bornhäuser, Martin;
Zandstra, Peter W.;
Werner, Carsten;
Pompe, Tilo

Publication type:

Article

Clonal evolution of stem and differentiated cells can be predicted by integrating cell-intrinsic and -extrinsic parameters.

Published in:

Biotechnology & Applied Biochemistry, 2005, v. 042, n. 2, p. 119

By:

Sowmya Viswanathan;
Ryan E. Davey;
Donavan Cheng;
Riyad C. Raghu;
Douglas A. Lauffenburger;
Peter W. Zandstra

Publication type:

Article

Microdroplet-based one-step RT-PCR for ultrahigh throughput single-cell multiplex gene expression analysis and rare cell detection.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-86087-4

By:

Ma, Jennifer;
Tran, Gary;
Wan, Alwin M. D.;
Young, Edmond W. K.;
Kumacheva, Eugenia;
Iscove, Norman N.;
Zandstra, Peter W.

Publication type:

Article

Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-85447-4

By:

Dziedzicka, Dominika;
Tewary, Mukul;
Keller, Alexander;
Tilleman, Laurentijn;
Prochazka, Laura;
Östblom, Joel;
Couvreu De Deckersberg, Edouard;
Markouli, Christina;
Franck, Silvie;
Van Nieuwerburgh, Filip;
Spits, Claudia;
Zandstra, Peter W.;
Sermon, Karen;
Geens, Mieke

Publication type:

Article

A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-62837-8

By:

Afshar, Mohammad E.;
Abraha, Haben Y.;
Bakooshli, Mohsen A.;
Davoudi, Sadegh;
Thavandiran, Nimalan;
Tung, Kayee;
Ahn, Henry;
Ginsberg, Howard J.;
Zandstra, Peter W.;
Gilbert, Penney M.

Publication type:

Article

Blood stem cell products: Toward sustainable benchmarks for clinical translation.

Published in:

BioEssays, 2013, v. 35, n. 3, p. 201, doi. 10.1002/bies.201200118

By:

Csaszar, Elizabeth;
Cohen, Sandra;
Zandstra, Peter W.

Publication type:

Article

PERT: A Method for Expression Deconvolution of Human Blood Samples from Varied Microenvironmental and Developmental Conditions.

Published in:

PLoS Computational Biology, 2012, v. 8, n. 12, p. 1, doi. 10.1371/journal.pcbi.1002838

By:

Wenlian Qiao;
Quon, Gerald;
Csaszar, Elizabeth;
Mei Yu;
Morris, Quaid;
Zandstra, Peter W.

Publication type:

Article

High-throughput fingerprinting of human pluripotent stem cell fate responses and lineage bias.

Published in:

Nature Methods, 2013, v. 10, n. 12, p. 1225, doi. 10.1038/nmeth.2684

By:

Nazareth, Emanuel J P;
Ostblom, Joel E E;
Lücker, Petra B;
Shukla, Shreya;
Alvarez, Manuel M;
Oh, Steve K W;
Yin, Ting;
Zandstra, Peter W

Publication type:

Article

Derivation, expansion and differentiation of induced pluripotent stem cells in continuous suspension cultures.

Published in:

Nature Methods, 2012, v. 9, n. 5, p. 509, doi. 10.1038/nmeth.1939

By:

Fluri, David A;
Tonge, Peter D;
Song, Hannah;
Baptista, Ricardo P;
Shakiba, Nika;
Shukla, Shreya;
Clarke, Geoffrey;
Nagy, Andras;
Zandstra, Peter W

Publication type:

Article

Pairing cells to enhance fusion.

Published in:

Nature Methods, 2009, v. 6, n. 2, p. 123, doi. 10.1038/nmeth0209-123

By:

Zandstra, Peter W.

Publication type:

Article

Functional immobilization of signaling proteins enables control of stem cell fate.

Published in:

Nature Methods, 2008, v. 5, n. 7, p. 645, doi. 10.1038/nmeth.1222

By:

Alberti, Kristin;
Davey, Ryan E.;
Onishi, Kento;
George, Sophia;
Salchert, Katrin;
Seib, F. Philipp;
Bornhäuser, Martin;
Pompe, Tilo;
Nagy, Andras;
Werner, Carsten;
Zandstra, Peter W.

Publication type:

Article

Integrative network analysis of signaling in human CD34<sup>+</sup> hematopoietic progenitor cells by global phosphoproteomic profiling using TiO<sub>2</sub> enrichment combined with 2D LC-MS/MS and pathway mapping.

Published in:

Proteomics, 2013, v. 13, n. 8, p. 1325, doi. 10.1002/pmic.201200369

By:

Guo, Hongbo;
Isserlin, Ruth;
Chen, Xiaoji;
Wang, Weijia;
Phanse, Sadhna;
Zandstra, Peter W.;
Paddison, Patrick J.;
Emili, Andrew

Publication type:

Article

T-Cell Differentiation from Hematopoietic Progenitor Cells Using 3D Thymic-like Hydrogels.

Published in:

GEN Biotechnology, 2024, v. 3, n. 3, p. 136, doi. 10.1089/genbio.2024.0010

By:

Primbetova, Asel;
Hsu, Han Hsuan;
Baker, Alexander;
Jones, Ross;
Zimmerman, Carla;
Shoichet, Molly;
Zandstra, Peter W.

Publication type:

Article

Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence.

Published in:

Nature Communications, 2017, v. 8, n. 5, p. 15380, doi. 10.1038/ncomms15380

By:

Rahman, Nafees;
Brauer, Patrick M.;
Ho, Lilian;
Usenko, Tatiana;
Tewary, Mukul;
Zúñiga-Pflücker, Juan Carlos;
Zandstra, Peter W.

Publication type:

Article

CD24 tracks divergent pluripotent states in mouse and human cells.

Published in:

Nature Communications, 2015, v. 6, n. 6, p. 7329, doi. 10.1038/ncomms8329

By:

Shakiba, Nika;
White, Carl A.;
Lipsitz, Yonatan Y.;
Yachie-Kinoshita, Ayako;
Tonge, Peter D;
Hussein, Samer M. I.;
Puri, Mira C.;
Elbaz, Judith;
Morrissey-Scoot, James;
Li, Mira;
Munoz, Javier;
Benevento, Marco;
Rogers, Ian M.;
Hanna, Jacob H.;
Heck, Albert J. R.;
Wollscheid, Bernd;
Nagy, Andras;
Zandstra, Peter W

Publication type:

Article

Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNF-signaling.

Published in:

Science Translational Medicine, 2017, v. 9, n. 421, p. 1

By:

Weijia Wang;
Hisaki Fujii;
Hye Jin Kim;
Hermansa, Karin;
Usenko, Tatiana;
Xie, Stephanie;
Zhi-Juan Luo;
Ma, Jennifer;
Celso, Cristina Lo;
Dick, John E.;
Krueger, Joerg;
Wall, Donna;
Egeler, R. Maarten;
Zandstra, Peter W.

Publication type:

Article

Proportional-Integral-Derivative (PID) Control of Secreted Factors for Blood Stem Cell Culture.

Published in:

PLoS ONE, 2015, v. 10, n. 9, p. 1, doi. 10.1371/journal.pone.0137392

By:

Caldwell, Julia;
Wang, Weijia;
Zandstra, Peter W.

Publication type:

Article

IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data.

Published in:

PLoS Computational Biology, 2022, v. 18, n. 2, p. 1, doi. 10.1371/journal.pcbi.1009907

By:

Heydari, Tiam;
A. Langley, Matthew;
Fisher, Cynthia L.;
Aguilar-Hidalgo, Daniel;
Shukla, Shreya;
Yachie-Kinoshita, Ayako;
Hughes, Michael;
M. McNagny, Kelly;
Zandstra, Peter W.

Publication type:

Article

Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying in Vitro Polarization?

Published in:

Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2018.00071

By:

Tedesco, Serena;
De Majo, Federica;
Kim, Jieun;
Trenti, Annalisa;
Trevisi, Lucia;
Fadini, Gian Paolo;
Bolego, Chiara;
Zandstra, Peter W.;
Cignarella, Andrea;
Vitiello, Libero

Publication type:

Article

Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells.

Published in:

Small, 2018, v. 14, n. 45, p. N.PAG, doi. 10.1002/smll.201803342

By:

Zhang, Shuailong;
Shakiba, Nika;
Chen, Yujie;
Zhang, Yanfeng;
Tian, Pengfei;
Singh, Jastaranpreet;
Chamberlain, M. Dean;
Satkauskas, Monika;
Flood, Andrew G.;
Kherani, Nazir P.;
Yu, Siyuan;
Zandstra, Peter W.;
Wheeler, Aaron R.

Publication type:

Article

Engineering a humanized bone organ model in mice to study bone metastases.

Published in:

Nature Protocols, 2017, v. 12, n. 4, p. 639, doi. 10.1038/nprot.2017.002

By:

Martine, Laure C;
Holzapfel, Boris M;
McGovern, Jacqui A;
Wagner, Ferdinand;
Quent, Verena M;
Hesami, Parisa;
Wunner, Felix M;
Vaquette, Cedryck;
De-Juan-Pardo, Elena M;
Brown, Toby D;
Nowlan, Bianca;
Wu, Dan Jing;
Hutmacher, Cosmo Orlando;
Moi, Davide;
Oussenko, Tatiana;
Piccinini, Elia;
Zandstra, Peter W;
Mazzieri, Roberta;
Lévesque, Jean-Pierre;
Dalton, Paul D

Publication type:

Article

Surfaceome Profiling Reveals Regulators of Neural Stem Cell Function.

Published in:

Stem Cells, 2014, v. 32, n. 1, p. 258, doi. 10.1002/stem.1550

By:

DeVeale, Brian;
Bausch-Fluck, Damaris;
Seaberg, Raewyn;
Runciman, Susan;
Akbarian, Vahe;
Karpowicz, Phillip;
Yoon, Charles;
Song, Hannah;
Leeder, Rachel;
Zandstra, Peter W.;
Wollscheid, Bernd;
Kooy, Derek

Publication type:

Article

Don't Look: Growing Clonal Versus Nonclonal Neural Stem Cell Colonies.

Published in:

Stem Cells, 2008, v. 26, n. 11, p. 2938, doi. 10.1634/stemcells.2008-0558

By:

Coles-Takabe, Brenda L. K.;
Brain, Ian;
Purpura, Kelly A.;
Karpowicz, Phillip;
Zandstra, Peter W.;
Morshead, Cindi M.;
van der Kooy, Derek

Publication type:

Article

Soluble Flt-1 Regulates Flk-1 Activation to Control Hematopoietic and Endothelial Development in an Oxygen-Responsive Manner.

Published in:

Stem Cells, 2008, v. 26, n. 11, p. 2832, doi. 10.1634/stemcells.2008-0237

By:

Purpura, Kelly A.;
George, Sophia H. L.;
Dang, Stephen M.;
Kyunghee Choi;
Nagy, Andras;
Zandstra, Peter W.

Publication type:

Article

Control of Human Embryonic Stem Cell Colony and Aggregate Size Heterogeneity Influences Differentiation Trajectories.

Published in:

Stem Cells, 2008, v. 26, n. 9, p. 2300, doi. 10.1634/stemcells.2008-0183

By:

Bauwens, Céline Liu;
Peerani, Raheem;
Niebruegge, Sylvia;
Woodhouse, Kimberly A.;
Kumacheva, Eugenia;
Husain, Mansoor;
Zandstra, Peter W.

Publication type:

Article

Spatial Organization of Embryonic Stem Cell Responsiveness to Autocrine Gp130 Ligands Reveals an Autoregulatory Stem Cell Niche.

Published in:

Stem Cells, 2006, v. 24, n. 11, p. 2538, doi. 10.1634/stemcells.2006-0216

By:

Davey, Ryan E.;
Zandstra, Peter W.

Publication type:

Article

Chemically controlled aggregation of pluripotent stem cells.

Published in:

Biotechnology & Bioengineering, 2018, v. 115, n. 8, p. 2061, doi. 10.1002/bit.26719

By:

Lipsitz, Yonatan Y.;
Tonge, Peter D.;
Zandstra, Peter W.

Publication type:

Article

A microgroove patterned multiwell cell culture plate for high-throughput studies of cell alignment.

Published in:

Biotechnology & Bioengineering, 2014, v. 111, n. 12, p. 2537, doi. 10.1002/bit.25298

By:

Lücker, Petra B.;
Javaherian, Sahar;
Soleas, John P.;
Halverson, Duncan;
Zandstra, Peter W.;
McGuigan, Alison P.

Publication type:

Article

Real-time monitoring and control of soluble signaling factors enables enhanced progenitor cell outputs from human cord blood stem cell cultures.

Published in:

Biotechnology & Bioengineering, 2014, v. 111, n. 6, p. 1258, doi. 10.1002/bit.25163

By:

Csaszar, Elizabeth;
Chen, Kun;
Caldwell, Julia;
Chan, Warren;
Zandstra, Peter W.

Publication type:

Article

High density continuous production of murine pluripotent cells in an acoustic perfused bioreactor at different oxygen concentrations.

Published in:

Biotechnology & Bioengineering, 2013, v. 110, n. 2, p. 648, doi. 10.1002/bit.24717

By:

Baptista, Ricardo P.;
Fluri, David A.;
Zandstra, Peter W.

Publication type:

Article

Rational bioprocess design for human pluripotent stem cell expansion and endoderm differentiation based on cellular dynamics.

Published in:

Biotechnology & Bioengineering, 2012, v. 109, n. 4, p. 853, doi. 10.1002/bit.24375

By:

Ungrin, Mark D.;
Clarke, Geoff;
Yin, Ting;
Niebrugge, Sylvia;
Nostro, M. Cristina;
Sarangi, Farida;
Wood, Geoffrey;
Keller, Gordon;
Zandstra, Peter W.

Publication type:

Article