Found: 25
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Knockouts model the 100 best-selling drugs--will they model the next 100?
- Published in:
- 2003
- By:
- Publication type:
- review
Efficient engraftment and viral transduction of human hepatocytes in an FRG rat liver humanization model.
- Published in:
- Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18119-6
- By:
- Publication type:
- Article
Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption
- Published in:
- Journal of Clinical Endocrinology & Metabolism, 2020, v. 105, n. 4, p. e1235, doi. 10.1210/clinem/dgz258
- By:
- Publication type:
- Article
Sotagliflozin Decreases Postprandial Glucose and Insulin Concentrations by Delaying Intestinal Glucose Absorption.
- Published in:
- 2019
- By:
- Publication type:
- journal article
High-Throughput Screening of Mouse Gene Knockouts Identifies Established and Novel High Body Fat Phenotypes.
- Published in:
- Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2021, v. 14, p. 3753, doi. 10.2147/DMSO.S322083
- By:
- Publication type:
- Article
Fatty acid desaturase 1 knockout mice are lean with improved glycemic control and decreased development of atheromatous plaque.
- Published in:
- Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2016, v. 9, p. 185, doi. 10.2147/dmso.s106653
- By:
- Publication type:
- Article
Sotagliflozin improves glycemic control in nonobese diabetes-prone mice with type 1 diabetes.
- Published in:
- Diabetes, Metabolic Syndrome & Obesity: Targets & Therapy, 2015, v. 8, p. 121, doi. 10.2147/DMSO.S76342
- By:
- Publication type:
- Article
Lrp5 functions in bone to regulate bone mass.
- Published in:
- Nature Medicine, 2011, v. 17, n. 6, p. 684, doi. 10.1038/nm.2388
- By:
- Publication type:
- Article
Telotristat etiprate for carcinoid syndrome: a single-arm, multicenter trial.
- Published in:
- 2015
- By:
- Publication type:
- Journal Article
Keratinocyte Migration in the Developing Eyelid Requires LIMK2.
- Published in:
- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0047168
- By:
- Publication type:
- Article
Development of sotagliflozin, a dual sodium-dependent glucose transporter 1/2 inhibitor.
- Published in:
- Diabetes & Vascular Disease Research, 2015, v. 12, n. 2, p. 101, doi. 10.1177/1479164114563304
- By:
- Publication type:
- Article
Autophagy protects tumors from T cell–mediated cytotoxicity via inhibition of TNFα-induced apoptosis.
- Published in:
- Science Immunology, 2020, v. 5, n. 54, p. 1, doi. 10.1126/sciimmunol.abb9561
- By:
- Publication type:
- Article
Study Design and Rationale of a Dose-Ranging Trial of LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Type 2 Diabetes Inadequately Controlled on Metformin Monotherapy.
- Published in:
- Clinical Cardiology, 2013, v. 36, n. 7, p. 367, doi. 10.1002/clc.22125
- By:
- Publication type:
- Article
NMIHBA results from hypomorphic PRUNE1 variants that lack short-chain exopolyphosphatase activity.
- Published in:
- Human Molecular Genetics, 2020, v. 29, n. 21, p. 3516, doi. 10.1093/hmg/ddaa237
- By:
- Publication type:
- Article
A Human Brain-Chip for Modeling Brain Pathologies and Screening Blood–Brain Barrier Crossing Therapeutic Strategies.
- Published in:
- Pharmaceutics, 2024, v. 16, n. 10, p. 1314, doi. 10.3390/pharmaceutics16101314
- By:
- Publication type:
- Article
Postsynaptic diacylglycerol lipase α mediates retrograde endocannabinoid suppression of inhibition in mouse prefrontal cortex.
- Published in:
- Journal of Physiology, 2011, v. 589, n. 20, p. 4857, doi. 10.1113/jphysiol.2011.212225
- By:
- Publication type:
- Article
Mouse Fkbp8 activity is required to inhibit cell death and establish dorso-ventral patterning in the posterior neural tube.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 4, p. 587, doi. 10.1093/hmg/ddm333
- By:
- Publication type:
- Article
Diacylglycerol lipase α knockout mice demonstrate metabolic and behavioral phenotypes similar to those of cannabinoid receptor 1 knockout mice.
- Published in:
- Frontiers in Endocrinology, 2015, v. 6, p. 1, doi. 10.3389/fendo.2015.00086
- By:
- Publication type:
- Article
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency.
- Published in:
- Science Translational Medicine, 2023, v. 15, n. 723, p. 1, doi. 10.1126/scitranslmed.add4897
- By:
- Publication type:
- Article
Sodium-Glucose Cotransporter Inhibitors: Effects on Renal and Intestinal Glucose Transport: From Bench to Bedside.
- Published in:
- 2015
- By:
- Publication type:
- journal article
Sotagliflozin, a Dual SGLT1 and SGLT2 Inhibitor, as Adjunct Therapy to Insulin in Type 1 Diabetes.
- Published in:
- Diabetes Care, 2015, v. 38, n. 7, p. 1181, doi. 10.2337/dc14-2806
- By:
- Publication type:
- Article
Greater Dose-Ranging Effects on A1C Levels Than on Glucosuria With LX4211, a Dual Inhibitor of SGLT1 and SGLT2, in Patients With Type 2 Diabetes on Metformin Monotherapy.
- Published in:
- Diabetes Care, 2015, v. 38, n. 3, p. 431, doi. 10.2337/dc14-0890
- By:
- Publication type:
- Article
Disruption and sequence identification of 2,000 genes in mouse embryonic stem cells.
- Published in:
- Nature, 1998, v. 392, n. 6676, p. 608, doi. 10.1038/33423
- By:
- Publication type:
- Article
Profound Obesity Secondary to Hyperphagia in Mice Lacking Kinase Suppressor of Ras 2.
- Published in:
- Obesity (19307381), 2011, v. 19, n. 5, p. 1010, doi. 10.1038/oby.2010.282
- By:
- Publication type:
- Article
High-throughput Screening of Mouse Knockout Lines Identifies True Lean and Obese Phenotypes.
- Published in:
- Obesity (19307381), 2008, v. 16, n. 10, p. 2362, doi. 10.1038/oby.2008.361
- By:
- Publication type:
- Article