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Safety study of topical naltrexone therapy for diabetic skin wounds is confirmed in Göttingen mini‐pigs.
- Published in:
- Drug Development Research, 2023, v. 84, n. 6, p. 1279, doi. 10.1002/ddr.22086
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- Article
Effects of Chronic Methadone Treatment on Maternal Body Weight and Food and Water Consumption in Rats.
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- Pharmacology, 1978, v. 17, n. 4, p. 227, doi. 10.1159/000136859
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- Publication type:
- Article
Effects of Chronic Morphine Administration on Pregnant Rats and Their Offspring.
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- Pharmacology, 1977, v. 15, n. 4, p. 302, doi. 10.1159/000136703
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- Publication type:
- Article
Morphine and Brain Growth Retardation in the Rat.
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- Pharmacology, 1977, v. 15, n. 3, p. 276, doi. 10.1159/000136699
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- Publication type:
- Article
Endogenous opioid systems and the regulation of dendritic growth and spine formation.
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- Journal of Comparative Neurology, 1989, v. 281, n. 1, p. 13, doi. 10.1002/cne.902810103
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- Publication type:
- Article
Topical naltrexone increases aquaporin 5 production in the lacrimal gland and restores tear production in diabetic rats.
- Published in:
- Experimental Biology & Medicine, 2024, p. 1, doi. 10.3389/ebm.2024.10175
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- Publication type:
- Article
Blockade of OGFr delays the onset and reduces the severity of diabetic ocular surface complications.
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- Experimental Biology & Medicine, 2021, v. 246, n. 5, p. 629, doi. 10.1177/1535370220972060
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- Publication type:
- Article
Dysregulation of the OGF–OGFr pathway correlates with elevated serum OGF and ocular surface complications in the diabetic rat.
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- Experimental Biology & Medicine, 2020, v. 245, n. 15, p. 1414, doi. 10.1177/1535370220940273
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- Publication type:
- Article
Intermittent blockade of OGFr and treatment of autoimmune disorders.
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- Experimental Biology & Medicine, 2018, v. 243, n. 17/18, p. 1323, doi. 10.1177/1535370218817746
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- Article
Featured Article: Modulation of the OGF–OGFr pathway alters cytokine profiles in experimental autoimmune encephalomyelitis and multiple sclerosis.
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- Experimental Biology & Medicine, 2018, v. 243, n. 4, p. 361, doi. 10.1177/1535370217749830
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- Publication type:
- Article
Serum [Met<sup>5</sup>]-enkephalin levels are reduced in multiple sclerosis and restored by low-dose naltrexone.
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- Experimental Biology & Medicine, 2017, v. 242, n. 15, p. 1524, doi. 10.1177/1535370217724791
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- Publication type:
- Article
Featured Article: Nuclear export of opioid growth factor receptor is CRM1 dependent.
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- Experimental Biology & Medicine, 2016, v. 241, n. 3, p. 273, doi. 10.1177/1535370215605585
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- Publication type:
- Article
Opioid growth factor and low-dose naltrexone impair central nervous system infiltration by CD4 + T lymphocytes in established experimental autoimmune encephalomyelitis, a model of multiple sclerosis.
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- Experimental Biology & Medicine, 2016, v. 241, n. 1, p. 71, doi. 10.1177/1535370215596384
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- Publication type:
- Article
Featured Article: Selective blockade of the OGF–OGFr pathway by naltrexone accelerates fibroblast proliferation and wound healing.
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- Experimental Biology & Medicine, 2014, v. 239, n. 10, p. 1300, doi. 10.1177/1535370214543061
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- Publication type:
- Article
Topical treatment with the opioid antagonist naltrexone accelerates the remodeling phase of full-thickness wound healing in type 1 diabetic rats.
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- Experimental Biology & Medicine, 2013, v. 238, n. 10, p. 1127, doi. 10.1177/1535370213502632
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- Publication type:
- Article
Topical naltrexone accelerates full-thickness wound closure in type 1 diabetic rats by stimulating angiogenesis.
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- Experimental Biology & Medicine, 2013, v. 238, n. 7, p. 733, doi. 10.1177/1535370213492688
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- Publication type:
- Article
Targeting the opioid growth factor: Opioid growth factor receptor axis for treatment of human ovarian cancer.
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- Experimental Biology & Medicine, 2013, v. 238, n. 5, p. 579, doi. 10.1177/1535370213488483
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- Publication type:
- Article
Under-expression of the opioid growth factor receptor promotes progression of human ovarian cancer.
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- Experimental Biology & Medicine, 2012, v. 237, n. 2, p. 167, doi. 10.1258/ebm.2011.011321
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- Publication type:
- Article
Topical treatment with the opioid antagonist naltrexone facilitates closure of full-thickness wounds in diabetic rats.
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- Experimental Biology & Medicine, 2011, v. 236, n. 10, p. 1122, doi. 10.1258/ebm.2011.011163
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- Publication type:
- Article
Low-dose naltrexone targets the opioid growth factor-opioid growth factor receptor pathway to inhibit cell proliferation: mechanistic evidence from a tissue culture model.
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- Experimental Biology & Medicine, 2011, v. 236, n. 9, p. 1036, doi. 10.1258/ebm.2011.011121
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- Publication type:
- Article
Low-dose naltrexone suppresses ovarian cancer and exhibits enhanced inhibition in combination with cisplatin.
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- Experimental Biology & Medicine, 2011, v. 236, n. 7, p. 883, doi. 10.1258/ebm.2011.011096
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- Publication type:
- Article
Naltrexone, an opioid antagonist, facilitates reepithelialization of the cornea in diabetic rat.
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- 2002
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- Publication type:
- journal article
Topical Treatment with Naltrexone Prevents Corneal Neovascularization in the Type 1 Diabetic Rat.
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- Diabetes, 2007, v. 56, p. A214
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- Publication type:
- Article
Corneal Epithelial Repair in Type I Diabetic Rats Is Enhanced by Topical Insulin Treatment.
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- Diabetes, 2007, v. 56, p. A214
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- Publication type:
- Article
Insulin Treatment Ameliorates Impaired Corneal Reepithelialization in Diabetic Rats.
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- Diabetes, 2006, v. 55, n. 4, p. 1141, doi. 10.2337/diabetes.55.04.06.db05-1581
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- Publication type:
- Article
The OGF-OGFr axis utilizes the p21 pathway to restrict progression of human pancreatic cancer.
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- Molecular Cancer, 2008, v. 7, p. 1, doi. 10.1186/1476-4598-7-5
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- Publication type:
- Article
Brain protein 4.1 subtypes: A working hypothesis.
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- BioEssays, 1987, v. 6, n. 6, p. 274, doi. 10.1002/bies.950060607
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- Publication type:
- Article
Comparative Effects of Postnatal Undernutrition and Methadone Exposure on Protein and Nucleic Acid Contents of the Brain and Cerebellum in Rats.
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- Developmental Neuroscience, 1982, v. 5, n. 5/6, p. 385, doi. 10.1159/000112698
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- Publication type:
- Article
Topical Application of Naltrexone to the Ocular Surface of Healthy Volunteers: A Tolerability Study.
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- 2016
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- Publication type:
- journal article
Topically Applied Naltrexone Restores Corneal Reepithelialization in Diabetic Rats.
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- Journal of Ocular Pharmacology & Therapeutics, 2007, v. 23, n. 2, p. 89, doi. 10.1089/jop.2006.0111
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- Publication type:
- Article
Corneal Safety of Topically Applied Naltrexone.
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- Journal of Ocular Pharmacology & Therapeutics, 2006, v. 22, n. 5, p. 377, doi. 10.1089/jop.2006.22.377
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- Publication type:
- Article
The Opioid Growth Factor, [Met<sup>5</sup>]-Enkephalin, and the ζ(Zeta) Opioid Receptor Are Present in Human and Mouse Skin and Tonically Act to Inhibit DNA Synthesis in the Epidermis.
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- Journal of Investigative Dermatology, 1996, v. 106, n. 3, p. 490, doi. 10.1111/1523-1747.ep12343712
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- Publication type:
- Article
Endogenous opioid inhibition of proliferation of T and B cell subpopulations in response to immunization for experimental autoimmune encephalomyelitis.
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- BMC Immunology, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12865-015-0093-0
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- Publication type:
- Article
Ontogeny of preproenkephalin mRNA expression in the rat retina.
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- Visual Neuroscience, 1996, v. 13, n. 4, p. 695, doi. 10.1017/S0952523800008580
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- Publication type:
- Article
Ontogeny of the opioid growth factor, [Met5]-enkephalin, and its binding activity in the rat retina.
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- Visual Neuroscience, 1995, v. 12, n. 5, p. 939, doi. 10.1017/S0952523800009494
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- Publication type:
- Article
Nucleocytoplasmic distribution of opioid growth factor and its receptor in tongue epithelium.
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- Anatomical Record: Advances in Integrative Anatomy & Evolutionary Biology, 2005, v. 282A, n. 1, p. 24, doi. 10.1002/ar.a.20161
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- Publication type:
- Article
Timing of treatment with an endogenous opioid alters immune response and spinal cord pathology in female mice with experimental autoimmune encephalomyelitis.
- Published in:
- Journal of Neuroscience Research, 2022, v. 100, n. 2, p. 551, doi. 10.1002/jnr.24983
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- Publication type:
- Article
[Met5]—enkephalin levels in the plasma of SCCHN are reduced following surgery
- Published in:
- 2003
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- Publication type:
- Abstract
Continuous delivery of opioid growth factor (OGF) inhibits SCCHN
- Published in:
- 2003
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- Publication type:
- Abstract
Low-Dose Naltrexone Therapy Improves Active Crohn's Disease.
- Published in:
- American Journal of Gastroenterology (Springer Nature), 2007, v. 102, n. 4, p. 820, doi. 10.1111/j.1572-0241.2007.01045.x
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- Publication type:
- Article
PERINATAL METHADONE EXPOSURE AND BRAIN DEVELOPMENT: A BIOCHEMICAL STUDY.
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- Journal of Neurochemistry, 1978, v. 31, n. 1, p. 49, doi. 10.1111/j.1471-4159.1978.tb12431.x
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- Publication type:
- Article
Efficacy and safety of a novel naltrexone treatment for dry eye in type 1 diabetes.
- Published in:
- 2019
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- Publication type:
- journal article
The Yin and Yang of the Opioid Growth Regulatory System: Focus on Diabetes—The Lorenz E. Zimmerman Tribute Lecture.
- Published in:
- Journal of Diabetes Research, 2016, p. 1, doi. 10.1155/2016/9703729
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- Publication type:
- Article
Mutations in the opioid growth factor receptor in human cancers alter receptor function.
- Published in:
- International Journal of Molecular Medicine, 2015, v. 36, n. 1, p. 289, doi. 10.3892/ijmm.2015.2221
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- Publication type:
- Article
Ocular surface abnormalities related to type 2 diabetes are reversed by the opioid antagonist naltrexone.
- Published in:
- Clinical & Experimental Ophthalmology, 2014, v. 42, n. 2, p. 159, doi. 10.1111/ceo.12144
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- Publication type:
- Article
Modulation of the opioid growth factor ([Met<sup>5</sup>]-enkephalin)-opioid growth factor receptor axis: Novel therapies for squamous cell carcinoma of the head and neck.
- Published in:
- Head & Neck, 2012, v. 34, n. 4, p. 513, doi. 10.1002/hed.21759
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- Publication type:
- Article
Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis.
- Published in:
- 2009
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- Publication type:
- journal article
Expression of Zeta (¥) a Growth-Related Opioid Receptor, in Metastetic Adenocarcinoma of the Human Cerebellum12.
- Published in:
- JNCI: Journal of the National Cancer Institute, 1990, v. 82, n. 4, p. 325
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- Publication type:
- Article
Topical insulin enhances corneal repair in Type 1 diabetic rats.
- Published in:
- FASEB Journal, 2007, v. 21, n. 6, p. A1200, doi. 10.1096/fasebj.21.6.a1200
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- Publication type:
- Article
Ontogeny of the opioid growth factor, [Met<sup>5</sup>]-enkephalin, preproenkephalin gene expression, and the ζ opioid receptor in the developing and adult aorta of rat.
- Published in:
- Developmental Dynamics, 1998, v. 211, n. 4, p. 327, doi. 10.1002/(SICI)1097-0177(199804)211:4<327::AID-AJA4>3.0.CO;2-J
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- Publication type:
- Article