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A Novel Approach to Increase Glial Cell Populations in Brain Microphysiological Systems.
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- Advanced Biology, 2024, v. 8, n. 8, p. 1, doi. 10.1002/adbi.202300198
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- Article
Intercellular communication atlas reveals Oprm1 as a neuroprotective factor for retinal ganglion cells.
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- Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46428-z
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- Article
Neutral sphingomyelinase inhibition promotes local and network degeneration in vitro and in vivo.
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- Cell Communication & Signaling, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12964-023-01291-1
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Regional Gene Expression in the Retina, Optic Nerve Head, and Optic Nerve of Mice with Optic Nerve Crush and Experimental Glaucoma.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13719, doi. 10.3390/ijms241813719
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IKKβ Inhibition Attenuates Epithelial Mesenchymal Transition of Human Stem Cell-Derived Retinal Pigment Epithelium.
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- Cells (2073-4409), 2023, v. 12, n. 8, p. 1155, doi. 10.3390/cells12081155
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Ex Vivo Integration of Human Stem Retinal Ganglion Cells into the Mouse Retina.
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- Cells (2073-4409), 2022, v. 11, n. 20, p. 3241, doi. 10.3390/cells11203241
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Aquaporin 4 is not present in normal porcine and human lamina cribrosa.
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- PLoS ONE, 2022, v. 17, n. 6, p. 1, doi. 10.1371/journal.pone.0268541
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Reactive Astrocytes Derived From Human Induced Pluripotent Stem Cells Suppress Oligodendrocyte Precursor Cell Differentiation.
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- Frontiers in Molecular Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnmol.2022.874299
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Temporal and Isoform-Specific Expression of CTBP2 Is Evolutionarily Conserved Between the Developing Chick and Human Retina.
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- Frontiers in Molecular Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnmol.2021.773356
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- Article
Complement component 3 from astrocytes mediates retinal ganglion cell loss during neuroinflammation.
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- Acta Neuropathologica, 2021, v. 142, n. 5, p. 899, doi. 10.1007/s00401-021-02366-4
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Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-20892-3
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Investigating cone photoreceptor development using patient-derived NRL null retinal organoids.
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- Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0808-5
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Targeted disruption of dual leucine zipper kinase and leucine zipper kinase promotes neuronal survival in a model of diffuse traumatic brain injury.
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- Molecular Neurodegeneration, 2019, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13024-019-0345-1
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PanoView: An iterative clustering method for single-cell RNA sequencing data.
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- PLoS Computational Biology, 2019, v. 15, n. 8, p. 1, doi. 10.1371/journal.pcbi.1007040
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Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis.
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- Acta Neuropathologica Communications, 2019, v. 7, n. 1, p. N.PAG, doi. 10.1186/s40478-019-0767-6
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- Article
Highly efficient scarless knock-in of reporter genes into human and mouse pluripotent stem cells via transient antibiotic selection.
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- PLoS ONE, 2018, v. 13, n. 11, p. 1, doi. 10.1371/journal.pone.0201683
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Three-Dimensional Retinal Organoids Facilitate the Investigation of Retinal Ganglion Cell Development, Organization and Neurite Outgrowth from Human Pluripotent Stem Cells.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32871-8
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- Article
ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03856-y
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- Article
Collagen vitrigels with low‐fibril density enhance human embryonic stem cell‐derived retinal pigment epithelial cell maturation.
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- Journal of Tissue Engineering & Regenerative Medicine, 2018, v. 12, n. 3, p. 821, doi. 10.1002/term.2598
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- Article
Enhanced Stem Cell Differentiation and Immunopurification of Genome Engineered Human Retinal Ganglion Cells.
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- Stem Cells Translational Medicine, 2017, v. 6, n. 11, p. 1972, doi. 10.1002/sctm.17-0059
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Automated segmentation of mouse OCT volumes (ASiMOV): Validation & clinical study of a light damage model.
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- PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0181059
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De novo assembly and annotation of the retinal transcriptome for the Nile grass rat (Arvicanthis ansorgei).
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- PLoS ONE, 2017, v. 12, n. 7, p. 1, doi. 10.1371/journal.pone.0179061
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Cornea organoids from human induced pluripotent stem cells.
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- Scientific Reports, 2017, p. 41286, doi. 10.1038/srep41286
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Off Target, but Sequence-Specific, shRNA-Associated Trans-Activation of Promoter Reporters in Transient Transfection Assays.
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- PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167867
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Serum molecular signature for proliferative diabetic retinopathy in Saudi patients with type 2 diabetes.
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- Molecular Vision, 2016, v. 22, p. 1
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Identification of an Alternative Splicing Product of the Otx2 Gene Expressed in the Neural Retina and Retinal Pigmented Epithelial Cells.
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- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150758
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Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line.
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- Scientific Reports, 2015, p. 16595, doi. 10.1038/srep16595
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- Article
Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation.
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- BMC Genomics, 2015, v. 16, n. 1, p. 1, doi. 10.1186/s12864-015-1271-4
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- Article
The Transcription Factor GTF2IRD1 Regulates the Topology and Function of Photoreceptors by Modulating Photoreceptor Gene Expression across the Retina.
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- Journal of Neuroscience, 2014, v. 34, n. 46, p. 15356, doi. 10.1523/JNEUROSCI.2089-14.2014
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Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs.
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- Nature Communications, 2014, v. 5, n. 8, p. 4516, doi. 10.1038/ncomms5516
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Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells.
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- International Journal of Nanomedicine, 2013, v. 8, p. 4641, doi. 10.2147/IJN.S53830
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- Article
Epigenetics and Cell Death: DNA Hypermethylation in Programmed Retinal Cell Death.
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- PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0079140
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Integrative analysis of tissue-specific methylation and alternative splicing identifies conserved transcription factor binding motifs.
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- Nucleic Acids Research, 2013, v. 41, n. 18, p. 8503, doi. 10.1093/nar/gkt652
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A novel methyl-binding domain protein enrichment method for identifying genome-wide tissue-specific DNA methylation from nanogram DNA samples.
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- Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-8935-6-17
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A functional variant in the CFI gene confers a high risk of age-related macular degeneration.
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- Nature Genetics, 2013, v. 45, n. 7, p. 813, doi. 10.1038/ng.2640
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Dynamics of Regulatory Networks in the Developing Mouse Retina.
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- PLoS ONE, 2012, v. 7, n. 10, p. 1, doi. 10.1371/journal.pone.0046521
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MITF-M, a 'melanocyte-specific' isoform, is expressed in the adult retinal pigment epithelium.
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- Pigment Cell & Melanoma Research, 2012, v. 25, n. 5, p. 641, doi. 10.1111/j.1755-148X.2012.01033.x
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- Article
Cell-Specific DNA Methylation Patterns of Retina-Specific Genes.
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- PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0032602
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A rare penetrant mutation in CFH confers high risk of age-related macular degeneration.
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- Nature Genetics, 2011, v. 43, n. 12, p. 1232, doi. 10.1038/ng.976
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Dynamic usage of alternative splicing exons during mouse retina development.
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- Nucleic Acids Research, 2011, v. 39, n. 18, p. 7920, doi. 10.1093/nar/gkr545
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Common variants near FRK/COL10A1 and VEGFA are associated with advanced age-related macular degeneration.
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- Human Molecular Genetics, 2011, v. 20, n. 18, p. 3699, doi. 10.1093/hmg/ddr270
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Expression of Rod-Derived Cone Viability Factor: Dual Role of CRX in Regulating Promoter Activity and Cell- Type Specificity.
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- PLoS ONE, 2010, v. 5, n. 10, p. 1, doi. 10.1371/journal.pone.0013075
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Computational analysis of tissue-specific gene networks: application to murine retinal functional studies.
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- Bioinformatics, 2010, v. 26, n. 18, p. 2289, doi. 10.1093/bioinformatics/btq408
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- Article
Baicalein reduces E46K α-synuclein aggregation in vitro and protects cells against E46K α-synuclein toxicity in cell models of familiar Parkinsonism.
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- Journal of Neurochemistry, 2010, v. 114, n. 2, p. 419, doi. 10.1111/j.1471-4159.2010.06752.x
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Prolonged blockade of VEGF receptors does not damage retinal photoreceptors or ganglion cells.
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- Journal of Cellular Physiology, 2010, v. 224, n. 1, p. 262, doi. 10.1002/jcp.22129
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The homeobox gene CHX10/VSX2 regulates RdCVF promoter activity in the inner retina.
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- Human Molecular Genetics, 2010, v. 19, n. 2, p. 250, doi. 10.1093/hmg/ddp484
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Relating periodicity of nucleosome organization and gene regulation.
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- Bioinformatics, 2009, v. 25, n. 14, p. 1782, doi. 10.1093/bioinformatics/btp323
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BEST1 expression in the retinal pigment epithelium is modulated by OTX family members.
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- Human Molecular Genetics, 2009, v. 18, n. 1, p. 128, doi. 10.1093/hmg/ddn323
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Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels.
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- Journal of Cellular Physiology, 2008, v. 217, n. 1, p. 13, doi. 10.1002/jcp.21445
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Analysis of regulatory network topology reveals functionally distinct classes of microRNAs.
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- Nucleic Acids Research, 2008, v. 36, n. 20, p. 6494, doi. 10.1093/nar/gkn712
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- Article