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Mechanisms of Transsynaptic Degeneration in the Aging Brain.
Published in:
Aging & Disease, 2024, v. 15, n. 5, p. 2149, doi. 10.14336/AD.2024.03019
By:
- Wall, Roshana Vander;
- Basavarajappa, Devaraj;
- Klistoner, Alexander;
- Graham, Stuart;
- Yuyi You
Publication type:
Article
Glial Cell Activation and Immune Responses in Glaucoma: A Systematic Review of Human Postmortem Studies of the Retina and Optic Nerve.
Published in:
Aging & Disease, 2024, v. 15, n. 5, p. 2069, doi. 10.14336/AD.2024.0103
By:
- Salkar, Akanksha;
- Wall, Roshana Vander;
- Basavarajappa, Devaraj;
- Chitranshi, Nitin;
- Parilla, Gabriella E.;
- Mirzaei, Mehdi;
- Peng Yan;
- Graham, Stuart;
- Yuyi You
Publication type:
Article
Glaucoma, More than Meets the Eye: Patterns of Demyelination Revealed in Human Postmortem Glaucomatous Optic Nerve.
Published in:
Aging & Disease, 2024, v. 15, n. 5, p. 2301, doi. 10.14336/AD.2024.0336-1
By:
- Parrilla, Gabriella E.;
- Salkar, Akanksha;
- Wall, Roshana Vander;
- Gupta, Vivek;
- Graham, Stuart L.;
- Yuyi You
Publication type:
Article
Brain-Derived Neurotrophic Factor Val66Met is Associated with Variation in Cortical Structure in Healthy Aging Subjects.
Published in:
Aging & Disease, 2024, v. 15, n. 5, p. 2315, doi. 10.14336/AD.2024.0346
By:
- Ting Shen;
- Sheriff, Samran;
- Yuyi You;
- Jiyang Jiang;
- Schulz, Angela;
- Francis, Heather;
- Mirzaei, Mehdi;
- Saks, Danit;
- Palanivel, Viswanthram;
- Basavarajappa, Devaraj;
- Chitranshi, Nitin;
- Gupta, Veer;
- Wen, Wei;
- Sachdev, Perminder S.;
- Huixun Jia;
- Xiaodong Sun;
- Graham, Stuart L.;
- Gupta, Vivek K.
Publication type:
Article
Demyelination precedes axonal loss in the transneuronal spread of human neurodegenerative disease.
Published in:
2019
By:
- You, Yuyi;
- Joseph, Chitra;
- Wang, Chenyu;
- Gupta, Vivek;
- Liu, Sidong;
- Yiannikas, Con;
- Chua, Brian E;
- Chitranshi, Nitin;
- Shen, Ting;
- Dheer, Yogita;
- Invernizzi, Alessandro;
- Borotkanics, Robert;
- Barnett, Michael;
- Graham, Stuart L;
- Klistorner, Alexander
Publication type:
journal article
Correlations between cognitive assessment and RNFL changes in OCT in healthy aging subjects.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052808
By:
- Shen, Ting;
- Sheriff, Samran;
- Schulz, Angela;
- You, Yuyi;
- Graham, Stuart;
- Gupta, Vivek K
Publication type:
Article
TrkB Receptor Signalling: Implications in Neurodegenerative, Psychiatric and Proliferative Disorders.
Published in:
International Journal of Molecular Sciences, 2013, v. 14, n. 5, p. 10122, doi. 10.3390/ijms140510122
By:
- Gupta, Vivek K.;
- You, Yuyi;
- Gupta, Veer Bala;
- Klistorner, Alexander;
- Graham, Stuart L.
Publication type:
Article
Structural and functional markers of optic nerve damage in myelin oligodendrocyte glycoprotein antibody-associated optic neuritis.
Published in:
Multiple Sclerosis Journal - Experimental, Translational & Clinical, 2021, p. 1, doi. 10.1177/20552173211063126
By:
- Barnes, Stephanie;
- You, Yuyi;
- Shen, Ting;
- Hardy, Todd A;
- Fraser, Clare;
- Reddel, Stephen W;
- Brilot, Fabienne;
- Ramanathan, Sudarshini;
- Klistorner, Alexandr;
- Yiannikas, Con
Publication type:
Article
Structural and functional markers of optic nerve damage in myelin oligodendrocyte glycoprotein antibody-associated optic neuritis.
Published in:
Multiple Sclerosis Journal - Experimental, Translational & Clinical, 2021, v. 7, n. 4, p. 1, doi. 10.1177/20552173211063126
By:
- Barnes, Stephanie;
- You, Yuyi;
- Shen, Ting;
- Hardy, Todd A;
- Fraser, Clare;
- Reddel, Stephen W;
- Brilot, Fabienne;
- Ramanathan, Sudarshini;
- Klistorner, Alexandr;
- Yiannikas, Con
Publication type:
Article
Protective Effects of 7,8-Dihydroxyflavone on Retinal Ganglion and RGC-5 Cells Against Excitotoxic and Oxidative Stress.
Published in:
Journal of Molecular Neuroscience, 2013, v. 49, n. 1, p. 96, doi. 10.1007/s12031-012-9899-x
By:
- Gupta, Vivek;
- You, Yuyi;
- Li, Jonathan;
- Klistorner, Alexander;
- Graham, Stuart
Publication type:
Article
Improving reproducibility of VEP recording in rats: electrodes, stimulus source and peak analysis.
Published in:
Documenta Ophthalmologica, 2011, v. 123, n. 2, p. 109, doi. 10.1007/s10633-011-9288-8
By:
- You, Yuyi;
- Klistorner, Alexander;
- Thie, Johnson;
- Graham, Stuart
Publication type:
Article
Expansion of chronic MS lesions is associated with an increase of radial diffusivity in periplaque white matter.
Published in:
Multiple Sclerosis Journal, 2022, v. 28, n. 5, p. 697, doi. 10.1177/13524585211033464
By:
- Klistorner, Samuel;
- Barnett, Michael H;
- Yiannikas, Con;
- Barton, Joshua;
- Parratt, John;
- You, Yuyi;
- Graham, Stuart L;
- Klistorner, Alexander
Publication type:
Article
Expansion of chronic lesions is linked to disease progression in relapsing–remitting multiple sclerosis patients.
Published in:
Multiple Sclerosis Journal, 2021, v. 27, n. 10, p. 1533, doi. 10.1177/1352458520974357
By:
- Klistorner, Samuel;
- Barnett, Michael H;
- Yiannikas, Con;
- Barton, Joshua;
- Parratt, John;
- You, Yuyi;
- Graham, Stuart L;
- Klistorner, Alexander
Publication type:
Article
Anterograde Degeneration along the Visual Pathway after Optic Nerve Injury.
Published in:
PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052061
By:
- You, Yuyi;
- Gupta, Vivek K.;
- Graham, Stuart L.;
- Klistorner, Alexander
Publication type:
Article
The effect of systemic and topical ophthalmic medications on choroidal thickness: A review.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 6, p. 2673, doi. 10.1111/bcp.15237
By:
- Yeung, Shanna C.;
- Park, Jamie Y.;
- Park, Daniel;
- You, Yuyi;
- Yan, Peng
Publication type:
Article
Differentiating axonal loss and demyelination in chronic MS lesions: A novel approach using single streamline diffusivity analysis.
Published in:
PLoS ONE, 2021, v. 16, n. 1, p. 1, doi. 10.1371/journal.pone.0244766
By:
- Klistorner, Samuel;
- Barnett, Michael H.;
- Wasserthal, Jakob;
- Yiannikas, Con;
- Barton, Joshua;
- Parratt, John;
- You, Yuyi;
- Graham, Stuart L.;
- Klistorner, Alexander
Publication type:
Article
Regulation of Brain-Derived Neurotrophic Factor and Growth Factor Signaling Pathways by Tyrosine Phosphatase Shp2 in the Retina: A Brief Review.
Published in:
Frontiers in Cellular Neuroscience, 2018, p. 1, doi. 10.3389/fncel.2018.00085
By:
- Abbasi, Mojdeh;
- Gupta, Vivek;
- Chitranshi, Nitin;
- You, Yuyi;
- Dheer, Yogita;
- Mirzaei, Mehdi;
- Graham, Stuart L.
Publication type:
Article
Neuroserpin, a crucial regulator for axogenesis, synaptic modelling and cell–cell interactions in the pathophysiology of neurological disease.
Published in:
Cellular & Molecular Life Sciences, 2022, v. 79, n. 3, p. 1, doi. 10.1007/s00018-022-04185-6
By:
- Godinez, Angela;
- Rajput, Rashi;
- Chitranshi, Nitin;
- Gupta, Veer;
- Basavarajappa, Devaraj;
- Sharma, Samridhi;
- You, Yuyi;
- Pushpitha, Kanishka;
- Dhiman, Kunal;
- Mirzaei, Mehdi;
- Graham, Stuart;
- Gupta, Vivek
Publication type:
Article
S1PR1 signaling attenuates apoptosis of retinal ganglion cells via modulation of cJun/Bim cascade and Bad phosphorylation in a mouse model of glaucoma.
Published in:
FASEB Journal, 2023, v. 37, n. 1, p. 1, doi. 10.1096/fj.202201346R
By:
- Basavarajappa, Devaraj;
- Gupta, Vivek;
- Wall, Roshana Vander;
- Gupta, Veer;
- Chitranshi, Nitin;
- Mirshahvaladi, Seyed Shahab Oddin;
- Palanivel, Viswanthram;
- Yuyi You;
- Mirzaei, Mehdi;
- Klistorner, Alexander;
- Graham, Stuart L.
Publication type:
Article
Fingolimod effects on the brain are mediated through biochemical modulation of bioenergetics, autophagy, and neuroinflammatory networks.
Published in:
Proteomics, 2022, v. 22, n. 19, p. 1, doi. 10.1002/pmic.202100247
By:
- Mirzaei, Mehdi;
- Abyadeh, Morteza;
- Turner, Anita J.;
- Wall, Roshana Vander;
- Chick, Joel M.;
- Paulo, Joao A.;
- Gupta, Veer K.;
- Basavarajappa, Devaraj;
- Chitranshi, Nitin;
- Mirshahvaladi, Seyed Shahab Oddin;
- You, Yuyi;
- Fitzhenry, Matthew J.;
- Amirkhani, Ardeshir;
- Haynes, Paul A.;
- Klistorner, Alexander;
- Gupta, Vivek;
- Graham, Stuart L.
Publication type:
Article
Oxidative Stress Induced Dysfunction of Protein Synthesis in 661W Mice Photoreceptor Cells.
Published in:
Proteomes, 2023, v. 11, n. 2, p. 12, doi. 10.3390/proteomes11020012
By:
- Deng, Liting;
- Gupta, Vivek;
- Abyadeh, Morteza;
- Chitranshi, Nitin;
- Pushpitha, Kanishka;
- Wu, Yunqi;
- Gupta, Veer;
- You, Yuyi;
- Paulo, Joao A.;
- Graham, Stuart L.;
- Mirzaei, Mehdi;
- Haynes, Paul A.
Publication type:
Article
Pathophysiological basis of low contrast visual acuity loss in multiple sclerosis.
Published in:
Annals of Clinical & Translational Neurology, 2018, v. 5, n. 12, p. 1505, doi. 10.1002/acn3.659
By:
- Triplett, James D.;
- Yiannikas, Con;
- Barnett, Michael H.;
- Parratt, John;
- Barton, Joshua;
- Graham, Stuart L.;
- You, Yuyi;
- Klistorner, Alexander
Publication type:
Article
Evolving geographic diversity in SARS-CoV2 and in silico analysis of replicating enzyme 3CL<sup>pro</sup> targeting repurposed drug candidates.
Published in:
2020
By:
- Chitranshi, Nitin;
- Gupta, Vivek K.;
- Rajput, Rashi;
- Godinez, Angela;
- Pushpitha, Kanishka;
- Shen, Ting;
- Mirzaei, Mehdi;
- You, Yuyi;
- Basavarajappa, Devaraj;
- Gupta, Veer;
- Graham, Stuart L.
Publication type:
journal article
Performance of iPad‐based threshold perimetry in glaucoma and controls.
Published in:
Clinical & Experimental Ophthalmology, 2018, v. 46, n. 4, p. 346, doi. 10.1111/ceo.13082
By:
- Schulz, Angela M.;
- Graham, Elizabeth C.;
- You, Yuyi;
- Klistorner, Alexander;
- Graham, Stuart L.
Publication type:
Article
BDNF Polymorphism: A Review of Its Diagnostic and Clinical Relevance in Neurodegenerative Disorders.
Published in:
Aging & Disease, 2018, v. 9, n. 3, p. 523, doi. 10.14336/AD.2017.0717
By:
- Ting Shen;
- Yuyi You;
- Joseph, Chitra;
- Mirzaei, Mehdi;
- Klistorner, Alexander;
- Graham, Stuart L.;
- Gupta, Vivek
Publication type:
Article
Association Between BDNF Val66Met Polymorphism and Optic Neuritis Damage in Neuromyelitis Optica Spectrum Disorder.
Published in:
Frontiers in Neuroscience, 2019, v. 13, p. 1, doi. 10.3389/fnins.2019.01236
By:
- Shen, Ting;
- Gupta, Vivek;
- Yiannikas, Con;
- Klistorner, Alexander;
- Graham, Stuart L.;
- You, Yuyi
Publication type:
Article
Inner retinal injury in experimental glaucoma is prevented upon AAV mediated Shp2 silencing in a caveolin dependent manner.
Published in:
Theranostics, 2021, v. 11, n. 13, p. 6154, doi. 10.7150/thno.55472
By:
- Abbasi, Mojdeh;
- Gupta, Vivek K.;
- Chitranshi, Nitin;
- Gupta, Veer;
- Ranjbaran, Reza;
- Rajput, Rashi;
- Pushpitha, Kanishka;
- K. B., Devaraj;
- Yuyi You;
- Salekdeh, Ghasem Hosseini;
- Parton, Robert G.;
- Mirzaei, Mehdi;
- Graham, Stuart L.
Publication type:
Article
Visualizing traumatic brain injury: ocular clues for diagnosis and assessment.
Published in:
Neural Regeneration Research, 2025, v. 20, n. 5, p. 1399, doi. 10.4103/NRR.NRR-D-23-01907
By:
- Abyadeh, Morteza;
- Gupta, Vivek;
- Yuyi You;
- Paulo, Joao A.;
- Mirzaei, Mehdi
Publication type:
Article
Amyloid-beta and tau protein beyond Alzheimer's disease.
Published in:
Neural Regeneration Research, 2024, v. 19, n. 6, p. 1262, doi. 10.4103/1673-5374.386406
By:
- Abyadeh, Morteza;
- Gupta, Vivek;
- Paulo, Joao A.;
- Mahmoudabad, Arezoo Gohari;
- Shadfar, Sina;
- Mirshahvaladi, Shahab;
- Gupta, Veer;
- Nguyen, Christine T. O.;
- Finkelstein, David I.;
- Yuyi You;
- Haynes, Paul A.;
- Salekdeh, Ghasem H.;
- Graham, Stuart L.;
- Mirzaei, Mehdi
Publication type:
Article
Retinal thickness and vascular parameters using optical coherence tomography in Alzheimer’s disease: a meta-analysis.
Published in:
Neural Regeneration Research, 2023, v. 18, n. 11, p. 2504, doi. 10.4103/1673-5374.371380
By:
- Sherif, Samran;
- Shen, Ting;
- Abdal, Sandra;
- Saks, Danit;
- Mirzaei, Mehdi;
- Gupta, Veer;
- Chitranshi, Nitin;
- You, Yuyi;
- Schultz, Angela;
- Graham, Stuart L.;
- Gupta, Vivek
Publication type:
Article
The role of myelin in neurodegeneration: implications for drug targets and neuroprotection strategies.
Published in:
Reviews in the Neurosciences, 2024, v. 35, n. 3, p. 271, doi. 10.1515/revneuro-2023-0081
By:
- Parrilla, Gabriella E.;
- Gupta, Vivek;
- Wall, Roshana Vander;
- Salkar, Akanksha;
- Basavarajappa, Devaraj;
- Mirzaei, Mehdi;
- Chitranshi, Nitin;
- Graham, Stuart L.;
- You, Yuyi
Publication type:
Article
Optic neuropathies: characteristic features and mechanisms of retinal ganglion cell loss.
Published in:
Reviews in the Neurosciences, 2013, v. 24, n. 3, p. 301, doi. 10.1515/revneuro-2013-0003
By:
- You, Yuyi;
- Gupta, Vivek K.;
- Li, Jonathan C.;
- Klistorner, Alexander;
- Graham, Stuart L.
Publication type:
Article
Anti-inflammatory Effects of Siponimod in a Mouse Model of Excitotoxicity-Induced Retinal Injury.
Published in:
Molecular Neurobiology, 2023, v. 60, n. 12, p. 7222, doi. 10.1007/s12035-023-03535-0
By:
- Basavarajappa, Devaraj;
- Gupta, Vivek;
- Chitranshi, Nitin;
- Viswanathan, Deepa;
- Gupta, Veer;
- Vander Wall, Roshana;
- Palanivel, Viswanthram;
- Mirzaei, Mehdi;
- You, Yuyi;
- Klistorner, Alexander;
- Graham, Stuart L.
Publication type:
Article
Correction to: Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement.
Published in:
2022
By:
- Sharma, Samridhi;
- Shen, Ting;
- Chitranshi, Nitin;
- Gupta, Veer;
- Basavarajappa, Devaraj;
- Sarkar, Soumalya;
- Mirzaei, Mehdi;
- You, Yuyi;
- Krezel, Wojciech;
- Graham, Stuart L.;
- Gupta, Vivek
Publication type:
Correction Notice
Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement.
Published in:
Molecular Neurobiology, 2022, v. 59, n. 4, p. 2027, doi. 10.1007/s12035-021-02709-y
By:
- Sharma, Samridhi;
- Shen, Ting;
- Chitranshi, Nitin;
- Gupta, Veer;
- Basavarajappa, Devaraj;
- Sarkar, Soumalya;
- Mirzaei, Mehdi;
- You, Yuyi;
- Krezel, Wojciech;
- Graham, Stuart L.;
- Gupta, Vivek
Publication type:
Article
Caveolin-1 Ablation Imparts Partial Protection Against Inner Retinal Injury in Experimental Glaucoma and Reduces Apoptotic Activation.
Published in:
Molecular Neurobiology, 2020, v. 57, n. 9, p. 3759, doi. 10.1007/s12035-020-01948-9
By:
- Abbasi, Mojdeh;
- Gupta, Vivek K.;
- Chitranshi, Nitin;
- Gupta, Veer B.;
- Mirzaei, Mehdi;
- Dheer, Yogita;
- Garthwaite, Linda;
- Zaw, Thiri;
- Parton, Robert G.;
- You, Yuyi;
- Graham, Stuart L.
Publication type:
Article
Bexarotene Modulates Retinoid-X-Receptor Expression and Is Protective Against Neurotoxic Endoplasmic Reticulum Stress Response and Apoptotic Pathway Activation.
Published in:
Molecular Neurobiology, 2018, v. 55, n. 12, p. 9043, doi. 10.1007/s12035-018-1041-9
By:
- Dheer, Yogita;
- Chitranshi, Nitin;
- Gupta, Veer;
- Abbasi, Mojdeh;
- Mirzaei, Mehdi;
- You, Yuyi;
- Chung, Roger;
- Graham, Stuart L.;
- Gupta, Vivek
Publication type:
Article
Diffusivity in the core of chronic multiple sclerosis lesions.
Published in:
PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0194142
By:
- Klistorner, Alexander;
- Wang, Chenyu;
- Yiannikas, Con;
- Parratt, John;
- Barton, Joshua;
- You, Yuyi;
- Graham, Stuart L.;
- Barnett, Michael H.
Publication type:
Article
Editorial: Retinal Changes in Neurological Diseases.
Published in:
Frontiers in Neuroscience, 2022, v. 15, p. 1, doi. 10.3389/fnins.2021.813044
By:
- Sharma, Samridhi;
- You, Yuyi
Publication type:
Article

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