Works by Yule, David I.

Results: 43

InsP3R–RyR Ca2+ channel crosstalk facilitates arrhythmias in the failing human ventricle.

Published in:

Basic Research in Cardiology, 2022, v. 117, n. 1, p. 1, doi. 10.1007/s00395-022-00967-y

By:

Jin, Xin;
Amoni, Matthew;
Gilbert, Guillaume;
Dries, Eef;
Doñate Puertas, Rosa;
Tomar, Ashutosh;
Nagaraju, Chandan K.;
Pradhan, Ankit;
Yule, David I.;
Martens, Tobie;
Menten, Roxane;
Vanden Berghe, Pieter;
Rega, Filip;
Sipido, Karin;
Roderick, H. Llewelyn

Publication type:

Article

Agonist activation of arachidonate-regulated Ca2+-selective (ARC) channels in murine parotid and pancreatic acinar cells.

Published in:

Journal of Physiology, 2005, v. 564, n. 3, p. 791, doi. 10.1113/jphysiol.2005.085704

By:

Mignen, Olivier;
Thompson, Jill L.;
Yule, David I.;
Shuttleworth, Trevor J.

Publication type:

Article

Cytosolic Ca2+ and Ca2+-activated Cl− current dynamics: insights from two functionally distinct mouse exocrine cells.

Published in:

Journal of Physiology, 2002, v. 540, n. 2, p. 469, doi. 10.1113/jphysiol.2001.013453

By:

Giovannucci, David R.;
Bruce, Jason I. E.;
Straub, Stephen V.;
Arreola, Jorge;
Sneyd, James;
Shuttleworth, Trevor J.;
Yule, David I.

Publication type:

Article

New saliva secretion model based on the expression of Na+-K+ pump and K+ channels in the apical membrane of parotid acinar cells.

Published in:

Pflügers Archiv: European Journal of Physiology, 2018, v. 470, n. 4, p. 613, doi. 10.1007/s00424-018-2109-0

By:

Almássy, János;
Siguenza, Elias;
Skaliczki, Marianna;
Matesz, Klara;
Sneyd, James;
Yule, David I.;
Nánási, Péter P.

Publication type:

Article

Loss of STIM1 and STIM2 in Salivary Glands Disrupts ANO1 Function but Does Not Induce Sjogren's Disease.

Published in:

Function, 2025, v. 6, n. 1, p. 1, doi. 10.1093/function/zqae047

By:

Son, Ga-Yeon;
Zou, Anna;
Wahl, Amanda;
Huang, Kai Ting;
Zorgit, Saruul;
Vinu, Manikandan;
Zhou, Fang;
Wagner, Larry;
Idaghdour, Youssef;
Yule, David I;
Feske, Stefan;
Lacruz, Rodrigo S

Publication type:

Article

Highly localized intracellular Ca2+ signals promote optimal salivary gland fluid secretion.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.66170

By:

Takahiro Takano;
Wahl, Amanda M.;
Kai-Ting Huang;
Narita, Takanori;
Rugis, John;
Sneyd, James;
Yule, David I.

Publication type:

Article

Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31959-0

By:

Yuan, Yu;
Jaślan, Dawid;
Rahman, Taufiq;
Bolsover, Stephen R.;
Arige, Vikas;
Wagner II, Larry E.;
Abrahamian, Carla;
Tang, Rachel;
Keller, Marco;
Hartmann, Jonas;
Rosato, Anna S.;
Weiden, Eva-Maria;
Bracher, Franz;
Yule, David I.;
Grimm, Christian;
Patel, Sandip

Publication type:

Article

Fluoride exposure alters Ca2+ signaling and mitochondrial function in enamel cells.

Published in:

Science Signaling, 2020, v. 13, n. 619, p. 1, doi. 10.1126/scisignal.aay0086

By:

Aulestia, Francisco J.;
Groeling, Johnny;
Bomfim, Guilherme H. S.;
Costiniti, Veronica;
Manikandan, Vinu;
Chaloemtoem, Ariya;
Concepcion, Axel R.;
Li, Yi;
Wagner II, Larry E.;
Idaghdour, Youssef;
Yule, David I.;
Lacruz, Rodrigo S.

Publication type:

Article

All three IP3 receptor isoforms generate Ca2+ puffs that display similar characteristics.

Published in:

Science Signaling, 2018, v. 11, n. 561, p. N.PAG, doi. 10.1126/scisignal.aau0344

By:

Lock, Jeffrey T.;
Alzayady, Kamil J.;
Yule, David I.;
Parker, Ian

Publication type:

Article

Phosphatidylinositol 4-phosphate is a major source of GPCR-stimulated phosphoinositide production.

Published in:

Science Signaling, 2018, v. 11, n. 547, p. 1, doi. 10.1126/scisignal.aan1210

By:

de Rubio, Rafael Gil;
Ransom, Richard F.;
Malik, Sundeep;
Yule, David I.;
Anantharam, Arun;
Smrcka, Alan V.

Publication type:

Article

Defining the stoichiometry of inositol 1,4,5-trisphosphate binding required to initiate Ca2+ release.

Published in:

Science Signaling, 2016, v. 9, n. 422, p. 1, doi. 10.1126/scisignal.aad6281

By:

Alzayady, Kamil J.;
Liwei Wang;
Chandrasekhar, Rahul;
Wagner II, Larry E.;
Van Petegem, Filip;
Yule, David I.

Publication type:

Article

Alpha-Helical Destabilization of the Bcl-2-BH4-Domain Peptide Abolishes Its Ability to Inhibit the IP3 Receptor.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0073386

By:

Monaco, Giovanni;
Decrock, Elke;
Nuyts, Koen;
Wagner II, Larry E.;
Luyten, Tomas;
Strelkov, Sergei V.;
Missiaen, Ludwig;
De Borggraeve, Wim M.;
Leybaert, Luc;
Yule, David I.;
De Smedt, Humbert;
Parys, Jan B.;
Bultynck, Geert

Publication type:

Article

Capture at the ER-mitochondrial contacts licenses IP3 receptors to stimulate local Ca2+ transfer and oxidative metabolism.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34365-8

By:

Katona, Máté;
Bartók, Ádám;
Nichtova, Zuzana;
Csordás, György;
Berezhnaya, Elena;
Weaver, David;
Ghosh, Arijita;
Várnai, Péter;
Yule, David I.;
Hajnóczky, György

Publication type:

Article

IP3RPEP6, a novel peptide inhibitor of IP3 receptor channels that does not affect connexin‐43 hemichannels.

Published in:

Acta Physiologica, 2024, v. 240, n. 3, p. 1, doi. 10.1111/apha.14086

By:

Tao, Siyu;
Hulpiau, Paco;
Wagner, Larry E.;
Witschas, Katja;
Yule, David I.;
Bultynck, Geert;
Leybaert, Luc

Publication type:

Article

IP3R deficit underlies loss of salivary fluid secretion in Sjögren's Syndrome.

Published in:

Scientific Reports, 2015, p. 13953, doi. 10.1038/srep13953

By:

Teos, Leyla Y.;
Zhang, Yu;
Cotrim, Ana P.;
Swaim, William;
Won, Jon H.;
Ambrus, Julian;
Shen, Long;
Bebris, Lolita;
Grisius, Margaret;
Jang, Shyh-Ing;
Yule, David I.;
Ambudkar, Indu S.;
Alevizos, Ilias

Publication type:

Article

Calcium and mitochondria

Published in:

FEBS Letters, 2004, v. 567, n. 1, p. 96, doi. 10.1016/j.febslet.2004.03.071

By:

Gunter, Thomas E.;
Yule, David I.;
Gunter, Karlene K.;
Eliseev, Roman A.;
Salter, Jason D.

Publication type:

Article

P3-370: Tumor necrosis factor-alpha potentiates neuronal muscarinic Ca2+ signals via regulation of inositol 1,4,5-trisphosphate receptor expression

Published in:

2008

By:

Park, Keigan M.;
Yule, David I.;
Bowers, William J.

Publication type:

Abstract

Simulation of Calcium Dynamics in Realistic Three-Dimensional Domains.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 10, p. N.PAG, doi. 10.3390/biom12101455

By:

Sneyd, James;
Rugis, John;
Su, Shan;
Suresh, Vinod;
Wahl, Amanda M.;
Yule, David I.

Publication type:

Article

The native ORAI channel trio underlies the diversity of Ca2+ signaling events.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-16232-6

By:

Yoast, Ryan E.;
Emrich, Scott M.;
Zhang, Xuexin;
Xin, Ping;
Johnson, Martin T.;
Fike, Adam J.;
Walter, Vonn;
Hempel, Nadine;
Yule, David I.;
Sneyd, James;
Gill, Donald L.;
Trebak, Mohamed

Publication type:

Article

Evidence That Calcium Entry Into Calcium-Transporting Dental Enamel Cells Is Regulated by Cholecystokinin, Acetylcholine and ATP.

Published in:

Frontiers in Physiology, 2018, p. N.PAG, doi. 10.3389/fphys.2018.00801

By:

Nurbaeva, Meerim K.;
Eckstein, Miriam;
Devotta, Arun;
Saint-Jeannet, Jean-Pierre;
Yule, David I.;
Hubbard, Michael J.;
Lacruz, Rodrigo S.

Publication type:

Article

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

Published in:

Biochemical Society Transactions, 2015, v. 43, n. 3, p. 364, doi. 10.1042/BST20140287

By:

Chandrasekhar, Rahul;
Alzayady, Kamil J.;
Yule, David I.

Publication type:

Article

Agonist-Specific Calcium Signaling and Phosphoinositide Hydrolysis in Human SK-N-MCIXC Neuroepithelioma Cells.

Published in:

Journal of Neurochemistry, 1994, v. 63, n. 6, p. 2099, doi. 10.1046/j.1471-4159.1994.63062099.x

By:

Palmer, R. Kyle;
Yule, David I.;
McEwen, Edward L.;
Williams, John A.;
Fisher, Stephen K.

Publication type:

Article

Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.

Published in:

2016

By:

Concepcion, Axel R.;
Vaeth, Martin;
Wagner II, Larry E.;
Eckstein, Miriam;
Hecht, Lee;
Jun Yang;
Crottes, David;
Seidl, Maximilian;
Hyosup P. Shin;
Weidinger, Carl;
Cameron, Scott;
Turvey, Stuart E.;
Issekutz, Thomas;
Meyts, Isabelle;
Lacruz, Rodrigo S.;
Cuk, Mario;
Yule, David I.;
Feske, Stefan;
Wagner, Larry E 2nd;
Yang, Jun

Publication type:

journal article

Magnesium Acts as a Second Messenger in the Regulation of NMDA Receptor-Mediated CREB Signaling in Neurons.

Published in:

Molecular Neurobiology, 2020, v. 57, n. 6, p. 2539, doi. 10.1007/s12035-020-01871-z

By:

Hou, Hailong;
Wang, Liwei;
Fu, Tianyue;
Papasergi, Makaia;
Yule, David I.;
Xia, Houhui

Publication type:

Article

Ca2+ tunneling architecture and function are important for secretion.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 1, p. 1, doi. 10.1083/jcb.202402107

By:

Courjaret, Raphael J.;
Wagner II, Larry E.;
Ammouri, Rahaf R.;
Yule, David I.;
Machaca, Khaled

Publication type:

Article

Neuronal and hormonal control of Ca2+ signalling in exocrine glands: insight from in vivo studies.

Published in:

Journal of Physiology, 2024, v. 602, n. 14, p. 3341, doi. 10.1113/JP285461

By:

Takano, Takahiro;
Yule, David I.

Publication type:

Article

Structural and functional analysis of salivary intercalated duct cells reveals a secretory phenotype.

Published in:

Journal of Physiology, 2023, v. 601, n. 20, p. 4539, doi. 10.1113/JP285104

By:

Wahl, Amanda M.;
Takano, Takahiro;
Su, Shan;
Warner, Blake M.;
Perez, Paola;
Sneyd, James;
Yule, David I.

Publication type:

Article

Ca2+ signals in pancreatic acinar cells in response to physiological stimulation in vivo.

Published in:

Journal of Physiology, 2023, v. 601, n. 12, p. 2391, doi. 10.1113/JP284469

By:

Takano, Takahiro;
Yule, David I.

Publication type:

Article

Calcium Dynamics and Water Transport in Salivary Acinar Cells.

Published in:

Bulletin of Mathematical Biology, 2021, v. 83, n. 4, p. 1, doi. 10.1007/s11538-020-00841-9

By:

Sneyd, James;
Vera-Sigüenza, Elias;
Rugis, John;
Pages, Nathan;
Yule, David I.

Publication type:

Article

A Multicellular Model of Primary Saliva Secretion in the Parotid Gland.

Published in:

Bulletin of Mathematical Biology, 2020, v. 82, n. 3, p. 1, doi. 10.1007/s11538-020-00712-3

By:

Vera-Sigüenza, Elías;
Pages, Nathan;
Rugis, John;
Yule, David I.;
Sneyd, James

Publication type:

Article

A Model of Ca2+ Dynamics in an Accurate Reconstruction of Parotid Acinar Cells.

Published in:

Bulletin of Mathematical Biology, 2019, v. 81, n. 5, p. 1394, doi. 10.1007/s11538-018-00563-z

By:

Pages, Nathan;
Vera-Sigüenza, Elías;
Rugis, John;
Kirk, Vivien;
Yule, David I.;
Sneyd, James

Publication type:

Article

A Mathematical Model of Fluid Transport in an Accurate Reconstruction of Parotid Acinar Cells.

Published in:

Bulletin of Mathematical Biology, 2019, v. 81, n. 3, p. 699, doi. 10.1007/s11538-018-0534-z

By:

Vera-Sigüenza, Elías;
Pages, Nathan;
Rugis, John;
Yule, David I.;
Sneyd, James

Publication type:

Article

Regulation of store-operated Ca2+ entry by IP3 receptors independent of their ability to release Ca2+.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.80447

By:

Chakraborty, Pragnya;
Deb, Bipan Kumar;
Arige, Vikas;
Musthafa, Thasneem;
Malik, Sundeep;
Yule, David I.;
Taylor, Colin W.;
Hasan, Gaiti

Publication type:

Article

Proteolytic fragmentation of inositol 1,4,5-trisphosphate receptors: a novel mechanism regulating channel activity?

Published in:

Journal of Physiology, 2016, v. 594, n. 11, p. 2867, doi. 10.1113/JP271140

By:

Wang, Liwei;
Alzayady, Kamil J.;
Yule, David I.

Publication type:

Article

Differential regulation of the InsP3 receptor type-1 and -2 single channel properties by InsP3, Ca2+ and ATP.

Published in:

Journal of Physiology, 2012, v. 590, n. 14, p. 3245, doi. 10.1113/jphysiol.2012.228320

By:

Wagner II, Larry E.;
Yule, David I.

Publication type:

Article

Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells.

Published in:

Journal of Physiology, 2012, v. 590, n. 11, p. 2721, doi. 10.1113/jphysiol.2012.228148

By:

Bhattacharya, Sumit;
Verrill, Douglas S.;
Carbone, Kristopher M.;
Brown, Stefanie;
Yule, David I.;
Giovannucci, David R.

Publication type:

Article

Regulation of single inositol 1,4,5-trisphosphate receptor channel activity by protein kinase A phosphorylation.

Published in:

Journal of Physiology, 2008, v. 586, n. 15, p. 3577, doi. 10.1113/jphysiol.2008.152314

By:

Wagner II, Larry E.;
Joseph, Suresh K.;
Yule, David I.

Publication type:

Article

Selective Inactivation of Intracellular BiP/GRP78 Attenuates Endothelial Inflammation and Permeability in Acute Lung Injury.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-38312-w

By:

Leonard, Antony;
Grose, Valerie;
Paton, Adrienne W.;
Paton, James C.;
Yule, David I.;
Rahman, Arshad;
Fazal, Fabeha

Publication type:

Article

IP3 receptor isoforms differently regulate ER-mitochondrial contacts and local calcium transfer.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11646-3

By:

Bartok, Adam;
Weaver, David;
Golenár, Tünde;
Nichtova, Zuzana;
Katona, Máté;
Bánsághi, Száva;
Alzayady, Kamil J.;
Thomas, V. Kaye;
Ando, Hideaki;
Mikoshiba, Katsuhiko;
Joseph, Suresh K.;
Yule, David I.;
Csordás, György;
Hajnóczky, György

Publication type:

Article

Dysregulated Ca2+ signaling, fluid secretion, and mitochondrial function in a mouse model of early Sjögren’s disease.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.97069

By:

Kai-Ting Huang;
Wagner, Larry E.;
Takahiro Takano;
Xiao-Xuan Lin;
Bagavant, Harini;
Deshmukh, Umesh;
Yule, David I.

Publication type:

Article

Stimulus-Secretion Coupling of Pancreatic Digestive Enzyme Secretion.

Published in:

Digestion, 1997, v. 58, n. S1, p. 42, doi. 10.1159/000201524

By:

Williams, John A.;
Groblewski, Guy E.;
Ohnishi, Hirohide;
Yule, David I.

Publication type:

Article

Tracing the Evolutionary History of Inositol, 1, 4, 5-Trisphosphate Receptor: Insights from Analyses of Capsaspora owczarzaki Ca2+ Release Channel Orthologs.

Published in:

Molecular Biology & Evolution, 2015, v. 32, n. 9, p. 2236, doi. 10.1093/molbev/msv098

By:

Alzayady, Kamil J.;
SebĊ-Pedrós, Arnau;
Chandrasekhar, Rahul;
Liwei Wang;
Ruiz-Trillo, ñaki;
Yule, David I.

Publication type:

Article

Bcl-2 and IP3 compete for the ligand-binding domain of IP3Rs modulating Ca2+ signaling output.

Published in:

Cellular & Molecular Life Sciences, 2019, v. 76, n. 19, p. 3843, doi. 10.1007/s00018-019-03091-8

By:

Ivanova, Hristina;
Wagner II, Larry E.;
Tanimura, Akihiko;
Vandermarliere, Elien;
Luyten, Tomas;
Welkenhuyzen, Kirsten;
Alzayady, Kamil J.;
Wang, Liwei;
Hamada, Kozo;
Mikoshiba, Katsuhiko;
De Smedt, Humbert;
Martens, Lennart;
Yule, David I.;
Parys, Jan B.;
Bultynck, Geert

Publication type:

Article