Found: 86
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Activation of GLP-1 receptor signalling alleviates cellular stresses and improves beta cell function in a mouse model of Wolfram syndrome.
- Published in:
- Diabetologia, 2018, v. 61, n. 10, p. 2189, doi. 10.1007/s00125-018-4679-y
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- Publication type:
- Article
Superior efficacy with a fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with insulin degludec and liraglutide in insulin‐naïve Japanese patients with type 2 diabetes in a phase 3, open‐label, randomized trial
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2674, doi. 10.1111/dom.13856
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- Publication type:
- Article
Superior efficacy with a fixed‐ratio combination of insulin degludec and liraglutide (IDegLira) compared with insulin degludec and liraglutide in insulin‐naïve Japanese patients with type 2 diabetes in a phase 3, open‐label, randomized trial
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 12, p. 2674, doi. 10.1111/dom.13856
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- Publication type:
- Article
Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52‐week data from the PROVIDE study.
- Published in:
- Diabetes, Obesity & Metabolism, 2019, v. 21, n. 7, p. 1737, doi. 10.1111/dom.13686
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- Publication type:
- Article
The combination of dulaglutide and biguanide reduced bodyweight in Japanese patients with type 2 diabetes.
- Published in:
- Diabetes, Obesity & Metabolism, 2016, v. 18, n. 12, p. 1279, doi. 10.1111/dom.12758
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- Publication type:
- Article
Unregulated elevation of glutamate dehydrogenase activity induces glutamine-stimulated insulin secretion: identification and characterization of a GLUD1 gene mutation and insulin secretion studies with MIN6 cells overexpressing the mutant glutamate dehydrogenase.
- Published in:
- 2002
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- Publication type:
- journal article
Unregulated Elevation of Glutamate Dehydrogenase Activity Induces Glutamine-Stimulated Insulin Secretion.
- Published in:
- Diabetes, 2002, v. 51, n. 3, p. 712, doi. 10.2337/diabetes.51.3.712
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- Publication type:
- Article
Troglitazone treatment increases plasma vascular endothelial growth factor in diabetic patients and its mRNA in 3T3-L1 adipocytes.
- Published in:
- 2001
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- Publication type:
- journal article
Genetic analysis of Japanese patients with persistent hyperinsulinemic hypoglycemia of infancy: nucleotide-binding fold-2 mutation impairs cooperative binding of adenine nucleotides to sulfonylurea receptor 1.
- Published in:
- 2000
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- Publication type:
- journal article
Identification and functional analysis of sulfonylurea receptor 1 variants in Japanese patients with NIDDM.
- Published in:
- 1998
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- Publication type:
- journal article
Genetics of NIDDM in France.
- Published in:
- Diabetes, 1997, v. 46, n. 6, p. 1062, doi. 10.2337/diab.46.6.1062
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- Publication type:
- Article
Isolation, characterization, and chromosomal mapping of the human insulin promoter factor 1 (IPF-1) gene.
- Published in:
- 1996
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- Publication type:
- journal article
Characterization of the LIM/homeodomain gene islet-1 and single nucleotide screening in NIDDM.
- Published in:
- 1995
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- Publication type:
- journal article
Isolation of the human LIM/homeodomain gene islet-1 and identification of a simple sequence repeat polymorphism [corrected].
- Published in:
- 1994
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- Publication type:
- journal article
Human glucagon-like peptide-1 receptor gene in NIDDM. Identification and use of simple sequence repeat polymorphisms in genetic analysis.
- Published in:
- 1994
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- Publication type:
- journal article
Polymorphic microsatellite repeat markers at the glucokinase gene locus are positively associated with NIDDM in Japanese.
- Published in:
- 1993
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- Publication type:
- journal article
Human Islet Glucokinase Gene.
- Published in:
- Diabetes, 1992, v. 41, n. 7, p. 807, doi. 10.2337/diab.41.7.807
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- Publication type:
- Article
Developmental regulation of amylin and insulin-gene expression in lean (Fa/Fa) and obese (fa/fa) Zucker rats.
- Published in:
- 1992
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- Publication type:
- journal article
Deficiency of WFS1 leads to the impairment of AVP secretion under dehydration in male mice.
- Published in:
- Pituitary, 2021, v. 24, n. 4, p. 582, doi. 10.1007/s11102-021-01135-6
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- Publication type:
- Article
E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis.
- Published in:
- Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06099-4
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- Publication type:
- Article
Myosin motor Myo1c and its receptor NEMO/IKK-γ promote TNF-α-induced serine<sup>307</sup> phosphorylation of IRS-1.
- Published in:
- Journal of Cell Biology, 2006, v. 173, n. 5, p. 665, doi. 10.1083/jcb.200601065
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- Publication type:
- Article
Genetic variants in the calpain-10 gene and the development of type 2 diabetes in the Japanese population.
- Published in:
- Journal of Human Genetics, 2005, v. 50, n. 2, p. 92, doi. 10.1007/s10038-004-0225-5
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- Publication type:
- Article
Wolfram syndrome 1 gene (WFS1) product localizes to secretory granules and determines granule acidification in pancreatic β-cells.
- Published in:
- Human Molecular Genetics, 2011, v. 20, n. 7, p. 1274, doi. 10.1093/hmg/ddq568
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- Publication type:
- Article
Disruption of the WFS1 gene in mice causes progressive β-cell loss and impaired stimulus–secretion coupling in insulin secretion.
- Published in:
- Human Molecular Genetics, 2004, v. 13, n. 11, p. 1159, doi. 10.1093/hmg/ddh125
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- Publication type:
- Article
231-LB: Importance of Intestinal Environment and Cellular Plasticity of Beta Cells in the Development of Post-Pancreatectomy Diabetes.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-231-LB
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- Publication type:
- Article
2037-P: Islet ß-Cell Dedifferentiation Is Involved in Progression of Type 2 Diabetes.
- Published in:
- Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-2037-P
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- Publication type:
- Article
323-LB: Activation of the GLP-1 Receptor Signaling Prevents Beta-Cell Dedifferentiation in a Mouse Model of Wolfram Syndrome through Modulating TXNIP Expression.
- Published in:
- Diabetes, 2019, v. 68, p. N.PAG, doi. 10.2337/db19-323-LB
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- Publication type:
- Article
DOC2B: A Novel Syntaxin-4 Binding Protein Mediating Insulin-Regulated GLUT4 Vesicle Fusion in Adipocytes.
- Published in:
- Diabetes, 2009, v. 58, n. 2, p. 377, doi. 10.2337/db08-0303
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- Publication type:
- Article
Double C2 Domain Protein (Doc2b) Regulates Insulin Secretion in Pancreatic Beta-Cells.
- Published in:
- Diabetes, 2007, v. 56, p. A436
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- Publication type:
- Article
GPI-Linked Proteoglycan p69 Regulates Glut4 Molecule at Caveolin-Rich Microdomains.
- Published in:
- Diabetes, 2007, v. 56, p. A329
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- Publication type:
- Article
Association Studies of Variants in the Genes Involved in Pancreatic β-Cell Function in Type 2 Diabetes in Japanese Subjects.
- Published in:
- Diabetes, 2006, v. 55, n. 8, p. 2379, doi. 10.2337/db05-1203
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- Publication type:
- Article
Gsk-3-Mediated Proteasomal Degradation of ATF4 Is a Proapoptotic Mechanism in Mouse Pancreatic β-Cells.
- Published in:
- International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13586, doi. 10.3390/ijms232113586
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- Publication type:
- Article
Hachimijiogan, a traditional herbal medicine, modulates adipose cell function and ameliorates diet-induced obesity and insulin resistance in mice.
- Published in:
- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1167934
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- Publication type:
- Article
Selective proteasome degradation of C‐terminally‐truncated human WFS1 in pancreatic beta cells.
- Published in:
- FEBS Open Bio, 2023, v. 13, n. 8, p. 1405, doi. 10.1002/2211-5463.13674
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- Publication type:
- Article
MEK kinase 1 is essential for Bcr–Abl-induced STAT3 and self-renewal activity in embryonic stem cells.
- Published in:
- Oncogene, 2005, v. 24, n. 51, p. 7592, doi. 10.1038/sj.onc.1208899
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- Publication type:
- Article
MEK kinase 1 mediates the antiapoptotic effect of the Bcr-Abl oncogene through NF-?B activation.
- Published in:
- Oncogene, 2003, v. 22, n. 49, p. 7774, doi. 10.1038/sj.onc.1206901
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- Publication type:
- Article
Endoplasmic reticulum stress induces Wfs1 gene expression in pancreatic {szligbeta}-cells via transcriptional activation.
- Published in:
- European Journal of Endocrinology, 2005, v. 153, n. 1, p. 167, doi. 10.1530/eje.1.01945
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- Publication type:
- Article
Dapagliflozin as Monotherapy or Combination Therapy in Japanese Patients with Type 2 Diabetes: an Open-Label Study.
- Published in:
- Diabetes Therapy, 2014, v. 5, n. 2, p. 415, doi. 10.1007/s13300-014-0086-7
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- Publication type:
- Article
Alteration in serum B cell-activating factor levels inpatients with idiopathic thrombocytopenic purpura after Helicobacter pylori eradication therapy.
- Published in:
- British Journal of Haematology, 2011, v. 152, n. 4, p. 496, doi. 10.1111/j.1365-2141.2010.08403.x
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- Publication type:
- Article
Nephrotic syndrome associated with thrombotic microangiopathy following allogeneic stem-cell transplantation for myelodysplastic syndrome.
- Published in:
- 2007
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- Publication type:
- Letter
Elevation of serum high-mobility group box 1 protein during granulocyte colony-stimulating factor-induced peripheral blood stem cell mobilisation.
- Published in:
- British Journal of Haematology, 2006, v. 135, n. 4, p. 567, doi. 10.1111/j.1365-2141.2006.06335.x
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- Publication type:
- Article
Molecular mimicry by Helicobacter pylori CagA protein may be involved in the pathogenesis of H. pylori-associated chronic idiopathic thrombocytopenic purpura.
- Published in:
- British Journal of Haematology, 2004, v. 124, n. 1, p. 91, doi. 10.1046/j.1365-2141.2003.04735.x
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- Publication type:
- Article
Increased serum levels of high-mobility group box 1 protein in patients who developed acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation.
- Published in:
- 2010
- By:
- Publication type:
- Letter
Autografting followed by a reduced-intensity conditioning unrelated donor cord blood transplantation for a patient with refractory multiple myeloma: successful engraftment with minimal toxicity.
- Published in:
- 2005
- By:
- Publication type:
- Book Review
Wolfram Syndrome in the Japanese Population; Molecular Analysis of WFS1 Gene and Characterization of Clinical Features.
- Published in:
- PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106906
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- Publication type:
- Article
Impairment of Visual Function and Retinal ER Stress Activation in <i>Wfs1</i>-Deficient Mice.
- Published in:
- PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097222
- By:
- Publication type:
- Article
Glucose and Fatty Acids Synergize to Promote B-Cell Apoptosis through Activation of Glycogen Synthase Kinase 3β Independent of JNK Activation.
- Published in:
- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0018146
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- Publication type:
- Article
A gene encoding a transmembrane protein is mutated in patients with diabetes mellitus and optic atrophy (Wolfram syndrome).
- Published in:
- Nature Genetics, 1998, v. 20, n. 2, p. 143, doi. 10.1038/2441
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- Publication type:
- Article
Severe congenital hyperinsulinism caused by a mutation in the Kir6.2 subunit of the adenosine triphosphate-sensitive potassium channel impairing trafficking and function.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Meat intake frequency and anemia in Japanese children and adolescents.
- Published in:
- 2012
- By:
- Publication type:
- Journal Article