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IL-33 promotes innate IFN-γ production and modulates dendritic cell response in LCMV-induced hepatitis in mice.
Published in:
European Journal of Immunology, 2015, v. 45, n. 11, p. 3052, doi. 10.1002/eji.201545696
By:
- Liang, Yuejin;
- Jie, Zuliang;
- Hou, Lifei;
- Yi, Panpan;
- Wang, Wei;
- Kwota, Zakari;
- Salvato, Maria;
- Waal Malefyt, Rene;
- Soong, Lynn;
- Sun, Jiaren
Publication type:
Article
Trem2/Syk/PI3K axis contributes to the host protection against Toxoplasma gondii-induced adverse pregnancy outcomes via modulating decidual macrophages.
Published in:
PLoS Pathogens, 2024, v. 20, n. 9, p. 1, doi. 10.1371/journal.ppat.1012543
By:
- Wang, Qing;
- Cao, Yining;
- Ye, Songyi;
- Ding, Maoyuan;
- Ge, Wenliang;
- Liang, Yuejin;
- Chen, Jinling
Publication type:
Article
Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.
Published in:
PLoS Pathogens, 2024, v. 20, n. 5, p. 1, doi. 10.1371/journal.ppat.1012020
By:
- Liang, Yuejin;
- Wang, Hui;
- Sun, Keer;
- Sun, Jiaren;
- Soong, Lynn
Publication type:
Article
Innate and Adaptive Immune Parameters following mRNA Vaccination in Mice.
Published in:
Vaccines, 2024, v. 12, n. 5, p. 543, doi. 10.3390/vaccines12050543
By:
- Bonam, Srinivasa Reddy;
- Hazell, Nicholas C.;
- Mathew, Mano Joseph;
- Liang, Yuejin;
- Zhang, Xuxiang;
- Wei, Zhi;
- Alameh, Mohamad-Gabriel;
- Weissman, Drew;
- Hu, Haitao
Publication type:
Article
CCR7/dendritic cell axis mediates early bacterial dissemination in Orientia tsutsugamushi-infected mice.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1061031
By:
- Yuejin Liang;
- Hui Wang;
- Gonzales, Casey;
- Thiriot, Joseph;
- Sunyakumthorn, Piyanate;
- Melby, Peter C.;
- Jiaren Sun;
- Lynn Soong
Publication type:
Article
Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.867924
By:
- Liang, Yuejin;
- Fisher, James;
- Gonzales, Casey;
- Trent, Brandon;
- Card, Galen;
- Sun, Jiaren;
- Tumanov, Alexei V.;
- Soong, Lynn
Publication type:
Article
IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice.
Published in:
PLoS Neglected Tropical Diseases, 2016, v. 10, n. 3, p. 1, doi. 10.1371/journal.pntd.0004467
By:
- Shelite, Thomas R.;
- Liang, Yuejin;
- Wang, Hui;
- Mendell, Nicole L.;
- Trent, Brandon J.;
- Sun, Jiaren;
- Gong, Bin;
- Xu, Guang;
- Hu, Haitao;
- Bouyer, Donald H.;
- Soong, Lynn
Publication type:
Article
IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice.
Published in:
2020
By:
- Liang, Yuejin;
- Yi, Panpan;
- Ru, Wenjuan;
- Jie, Zuliang;
- Wang, Hui;
- Ghanayem, Tamer;
- Wang, Xiaofang;
- Alamer, Edrous;
- Liu, Jinjun;
- Hu, Haitao;
- Soong, Lynn;
- Cai, Jiyang;
- Sun, Jiaren
Publication type:
journal article
Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005765
By:
- Soong, Lynn;
- Shelite, HeThomas R.;
- Xing, Yan;
- Kodakandla, Harica;
- Liang, Yuejin;
- Trent, Brandon J.;
- Horton, Paulina;
- Smith, Kathryn C.;
- Zhao, Zhenyang;
- Sun, Jiaren;
- Bouyer, Donald H.;
- Cai, Jiyang
Publication type:
Article
CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.
Published in:
PLoS Neglected Tropical Diseases, 2017, v. 11, n. 7, p. 1, doi. 10.1371/journal.pntd.0005763
By:
- Xu, Guang;
- Mendell, Nicole L.;
- Liang, Yuejin;
- Shelite, Thomas R.;
- Goez-Rivillas, Yenny;
- Soong, Lynn;
- Bouyer, Donald H.;
- Walker, David H.
Publication type:
Article
Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses.
Published in:
PLoS Pathogens, 2021, v. 17, n. 7, p. 1, doi. 10.1371/journal.ppat.1009782
By:
- Fisher, James;
- Card, Galen;
- Liang, Yuejin;
- Trent, Brandon;
- Rosenzweig, Holly;
- Soong, Lynn
Publication type:
Article
Correction: CD8+ T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.
Published in:
2017
By:
- Xu, Guang;
- Mendell, Nicole L.;
- Liang, Yuejin;
- Shelite, Thomas R.;
- Goez-Rivillas, Yenny;
- Soong, Lynn;
- Bouyer, Donald H.;
- Walker, David H.
Publication type:
Correction Notice
Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants.
Published in:
NPJ Vaccines, 2024, v. 9, n. 1, p. 1, doi. 10.1038/s41541-024-00957-2
By:
- Hajnik, Renee L.;
- Plante, Jessica A.;
- Reddy Bonam, Srinivasa;
- Rafael, Grace H.;
- Liang, Yuejin;
- Hazell, Nicholas C.;
- Walker, Jordyn;
- Reyna, Rachel A.;
- Walker, David H.;
- Alameh, Mohamad-Gabriel;
- Weissman, Drew;
- Weaver, Scott C.;
- Plante, Kenneth S.;
- Hu, Haitao
Publication type:
Article
Brain transcriptomics reveal the activation of neuroinflammation pathways during acute Orientia tsutsugamushi infection in mice.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1194881
By:
- Yuejin Liang;
- Aditi;
- Florence Onyoni;
- Hui Wang;
- Casey Gonzales;
- Piyanate Sunyakumthorn;
- Ping Wu;
- Parimal Samir;
- Lynn Soong
Publication type:
Article
Editorial: Deleterious and beneficial humoral immune response in viral diseases: Two sides of the same coin.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1185852
By:
- Feng-Liang Liu;
- Yuejin Liang;
- Pengfei Wang;
- Yong-Tang Zheng
Publication type:
Article
A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta.
Published in:
Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1135815
By:
- Carter, Brandon;
- Pinghan Huang;
- Ge Liu;
- Yuejin Liang;
- Lin, Paulo J. C.;
- Bi-Hung Peng;
- McKay, Lindsay G. A.;
- Dimitrakakis, Alexander;
- Hsu, Jason;
- Tat, Vivian;
- Saenkham-Huntsinger, Panatda;
- Jinjin Chen;
- Kaseke, Clarety;
- Gaiha, Gaurav D.;
- Qiaobing Xu;
- Griffiths, Anthony;
- Tam, Ying K.;
- Tseng, Chien-Te K.;
- Gifford, David K.
Publication type:
Article
Polarized lung inflammation and tie2/angiopoietin-mediated endothelial dysfunction during severe orientia tsutsugamushi infection.
Published in:
PLoS Neglected Tropical Diseases, 2020, v. 14, n. 3, p. 1, doi. 10.1371/journal.pntd.0007675
By:
- Trent, Brandon;
- Liang, Yuejin;
- Xing, Yan;
- Esqueda, Marisol;
- Wei, Yang;
- Cho, Nam-Hyuk;
- Kim, Hong-Il;
- Kim, Yeon-Sook;
- Shelite, Thomas R.;
- Cai, Jiyang;
- Sun, Jiaren;
- Bouyer, Donald H.;
- Liu, Jinjun;
- Soong, Lynn
Publication type:
Article
Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury.
Published in:
FASEB Journal, 2017, v. 31, n. 11, p. 4903, doi. 10.1096/fj.201700533R
By:
- Zhenyang Zhao;
- Yuejin Liang;
- Yin Liu;
- Pei Xu;
- Flamme-Wiese, Miles J.;
- Deming Sun;
- Jiaren Sun;
- Mullins, Robert F.;
- Yan Chen;
- Jiyang Cai
Publication type:
Article
Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages.
Published in:
Pathogens, 2023, v. 12, n. 1, p. 53, doi. 10.3390/pathogens12010053
By:
- Fisher, James;
- Gonzales, Casey;
- Chroust, Zachary;
- Liang, Yuejin;
- Soong, Lynn
Publication type:
Article
Host EPAC1 Modulates Rickettsial Adhesion to Vascular Endothelial Cells via Regulation of ANXA2 Y23 Phosphorylation.
Published in:
Pathogens, 2021, v. 10, n. 10, p. 1307, doi. 10.3390/pathogens10101307
By:
- Su, Zhengchen;
- Shelite, Thomas R.;
- Qiu, Yuan;
- Chang, Qing;
- Wakamiya, Maki;
- Bei, Jiani;
- He, Xi;
- Zhou, Changcheng;
- Liu, Yakun;
- Nyong, Emmanuel;
- Liang, Yuejin;
- Gaitas, Angelo;
- Saito, Tais B.;
- Gong, Bin
Publication type:
Article
The Role of IL-36 in Infectious Diseases: Potential Target for COVID-19?
Published in:
Frontiers in Immunology, 2021, v. 12, p. N.PAG, doi. 10.3389/fimmu.2021.662266
By:
- Wang, Xiaofang;
- Yi, Panpan;
- Liang, Yuejin
Publication type:
Article
Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.638575
By:
- Xu, Lanman;
- Wang, Xiaofang;
- Chen, Yan;
- Soong, Lynn;
- Chen, Yongping;
- Cai, Jiyang;
- Liang, Yuejin;
- Sun, Jiaren
Publication type:
Article
The Role of IL-36 in Infectious Diseases: Potential Target for COVID-19?
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.662266
By:
- Wang, Xiaofang;
- Yi, Panpan;
- Liang, Yuejin
Publication type:
Article
Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice.
Published in:
Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.651191
By:
- Wang, Hui;
- Wang, Gangduo;
- Banerjee, Nivedita;
- Liang, Yuejin;
- Du, Xiaotang;
- Boor, Paul J.;
- Hoffman, Kristi L.;
- Khan, M. Firoze
Publication type:
Article
Differentiation and Function of T Cell Subsets in Infectious Diseases.
Published in:
2018
By:
- Liang, Yuejin;
- Chen, Xiaojun;
- Chen, Jinling;
- Liu, Fengliang
Publication type:
Editorial
Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies.
Published in:
NPJ Vaccines, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41541-021-00405-5
By:
- Zhong, Chaojie;
- Xia, Hongjie;
- Adam, Awadalkareem;
- Wang, Binbin;
- Hajnik, Renee L.;
- Liang, Yuejin;
- Rafael, Grace H.;
- Zou, Jing;
- Wang, Xiaofang;
- Sun, Jiaren;
- Soong, Lynn;
- Barrett, Alan D. T.;
- Weaver, Scott C.;
- Shi, Pei-Yong;
- Wang, Tian;
- Hu, Haitao
Publication type:
Article
An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.
Published in:
NPJ Vaccines, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41541-019-0143-3
By:
- Li, Guangyu;
- Adam, Awadalkareem;
- Luo, Huanle;
- Shan, Chao;
- Cao, Zengguo;
- Fontes-Garfias, Camila R.;
- Sarathy, Vanessa V.;
- Teleki, Cody;
- Winkelmann, Evandro R.;
- Liang, Yuejin;
- Sun, Jiaren;
- Bourne, Nigel;
- Barrett, Alan D. T.;
- Shi, Pei-Yong;
- Wang, Tian
Publication type:
Article
Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance.
Published in:
Journal of Innate Immunity, 2015, v. 7, n. 4, p. 354, doi. 10.1159/000373923
By:
- Carlsen, Eric D.;
- Jie, Zuliang;
- Liang, Yuejin;
- Henard, Calvin a.;
- Hay, Christie;
- Sun, Jiaren;
- de Matos Guedes, Herbert;
- Soong, Lynn
Publication type:
Article
Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003191
By:
- Soong, Lynn;
- Wang, Hui;
- Shelite, Thomas R.;
- Liang, Yuejin;
- Mendell, Nicole L.;
- Sun, Jiaren;
- Gong, Bin;
- Valbuena, Gustavo A.;
- Bouyer, Donald H.;
- Walker, David H.
Publication type:
Article
Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice.
Published in:
PLoS Neglected Tropical Diseases, 2014, v. 8, n. 9, p. 1, doi. 10.1371/journal.pntd.0003191
By:
- Soong, Lynn;
- Wang, Hui;
- Shelite, Thomas R.;
- Liang, Yuejin;
- Mendell, Nicole L.;
- Sun, Jiaren;
- Gong, Bin;
- Valbuena, Gustavo A.;
- Bouyer, Donald H.;
- Walker, David H.
Publication type:
Article
IL‐33 activates mTORC1 and modulates glycolytic metabolism in CD8+ T cells.
Published in:
Immunology, 2022, v. 165, n. 1, p. 61, doi. 10.1111/imm.13404
By:
- Liang, Yuejin;
- Wang, Xiaofang;
- Wang, Hui;
- Yang, Wenjing;
- Yi, Panpan;
- Soong, Lynn;
- Cong, Yingzi;
- Cai, Jiyang;
- Fan, Xuegong;
- Sun, Jiaren
Publication type:
Article
Vascular endothelial growth factor promotes the activation of hepatic stellate cells in chronic schistosomiasis.
Published in:
Immunology & Cell Biology, 2017, v. 95, n. 4, p. 399, doi. 10.1038/icb.2016.109
By:
- Luo, Jie;
- Liang, Yuejin;
- Kong, Fanping;
- Qiu, Jingfan;
- Liu, Xinjian;
- Chen, Ailing;
- Luxon, Bruce A;
- Wu, Hannah W;
- Wang, Yong
Publication type:
Article
Editorial: Immunological aspects of emerging and re-emerging zoonoses.
Published in:
Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1392382
By:
- Wei Wang;
- Jingxin Li;
- Yuejin Liang;
- Wenping Gong
Publication type:
Article
Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models.
Published in:
Science Translational Medicine, 2022, v. 14, n. 662, p. 1, doi. 10.1126/scitranslmed.abq1945
By:
- Hajnik, Renee L.;
- Plante, Jessica A.;
- Liang, Yuejin;
- Alameh, Mohamad-Gabriel;
- Tang, Jinyi;
- Bonam, Srinivasa Reddy;
- Zhong, Chaojie;
- Adam, Awadalkareem;
- Scharton, Dionna;
- Rafael, Grace H.;
- Liu, Yang;
- Hazell, Nicholas C.;
- Sun, Jiaren;
- Soong, Lynn;
- Shi, Pei-Yong;
- Wang, Tian;
- Walker, David H.;
- Sun, Jie;
- Weissman, Drew;
- Weaver, Scott C.
Publication type:
Article
Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice.
Published in:
PLoS Neglected Tropical Diseases, 2023, v. 17, n. 12, p. 1, doi. 10.1371/journal.pntd.0011445
By:
- Thiriot, Joseph D.;
- Liang, Yuejin;
- Gonzales, Casey;
- Sun, Jiaren;
- Yu, Xiaoying;
- Soong, Lynn
Publication type:
Article
Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice.
Published in:
PLoS Neglected Tropical Diseases, 2023, v. 16, n. 5, p. 1, doi. 10.1371/journal.pntd.0011090
By:
- Gonzales, Casey;
- Liang, Yuejin;
- Fisher, James;
- Card, Galen;
- Sun, Jiaren;
- Soong, Lynn
Publication type:
Article
Correction: Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi.
Published in:
2023
By:
- Thiriot, Joseph;
- Liang, Yuejin;
- Fisher, James;
- Walker, David H.;
- Soong, Lynn
Publication type:
Correction Notice
Hepatocyte growth factor in dampening liver immune-mediated pathology in acute viral hepatitis without compromising antiviral activity.
Published in:
Journal of Gastroenterology & Hepatology, 2014, v. 29, n. 4, p. 878, doi. 10.1111/jgh.12456
By:
- Aguilar‐Valenzuela, Renan;
- Carlsen, Eric D.;
- Liang, Yuejin;
- Soong, Lynn;
- Sun, Jiaren
Publication type:
Article
Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi.
Published in:
PLoS Neglected Tropical Diseases, 2022, v. 16, n. 11, p. 1, doi. 10.1371/journal.pntd.0010459
By:
- Thiriot, Joseph;
- Liang, Yuejin;
- Fisher, James;
- Walker, David H.;
- Soong, Lynn
Publication type:
Article

Found: 39

IL-33 promotes innate IFN-γ production and modulates dendritic cell response in LCMV-induced hepatitis in mice.

Trem2/Syk/PI3K axis contributes to the host protection against Toxoplasma gondii-induced adverse pregnancy outcomes via modulating decidual macrophages.

Lack of the IFN-γ signal leads to lethal Orientia tsutsugamushi infection in mice with skin eschar lesions.

Innate and Adaptive Immune Parameters following mRNA Vaccination in Mice.

CCR7/dendritic cell axis mediates early bacterial dissemination in Orientia tsutsugamushi-infected mice.

Distinct Role of TNFR1 and TNFR2 in Protective Immunity Against Orientia tsutsugamushi Infection in Mice.

IL-33-Dependent Endothelial Activation Contributes to Apoptosis and Renal Injury in Orientia tsutsugamushi-Infected Mice.

IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice.

Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice.

CD8<sup>+</sup> T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.

Orientia tsutsugamushi selectively stimulates the C-type lectin receptor Mincle and type 1-skewed proinflammatory immune responses.

Correction: CD8<sup>+</sup> T cells provide immune protection against murine disseminated endotheliotropic Orientia tsutsugamushi infection.

Broad protection and respiratory immunity of dual mRNA vaccination against SARS-CoV-2 variants.

Brain transcriptomics reveal the activation of neuroinflammation pathways during acute Orientia tsutsugamushi infection in mice.

Editorial: Deleterious and beneficial humoral immune response in viral diseases: Two sides of the same coin.

A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta.

Polarized lung inflammation and tie2/angiopoietin-mediated endothelial dysfunction during severe orientia tsutsugamushi infection.

Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury.

Orientia tsutsugamushi Infection Stimulates Syk-Dependent Responses and Innate Cytosolic Defenses in Macrophages.

Host EPAC1 Modulates Rickettsial Adhesion to Vascular Endothelial Cells via Regulation of ANXA2 Y23 Phosphorylation.

The Role of IL-36 in Infectious Diseases: Potential Target for COVID-19?

Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis.

The Role of IL-36 in Infectious Diseases: Potential Target for COVID-19?

Aberrant Gut Microbiome Contributes to Intestinal Oxidative Stress, Barrier Dysfunction, Inflammation and Systemic Autoimmune Responses in MRL/lpr Mice.

Differentiation and Function of T Cell Subsets in Infectious Diseases.

Mucosal vaccination induces protection against SARS-CoV-2 in the absence of detectable neutralizing antibodies.

An attenuated Zika virus NS4B protein mutant is a potent inducer of antiviral immune responses.

Interactions between Neutrophils and Leishmania braziliensis Amastigotes Facilitate Cell Activation and Parasite Clearance.

Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice.

Strong Type 1, but Impaired Type 2, Immune Responses Contribute to Orientia tsutsugamushi-Induced Pathology in Mice.

IL‐33 activates mTORC1 and modulates glycolytic metabolism in CD8<sup>+</sup> T cells.

Vascular endothelial growth factor promotes the activation of hepatic stellate cells in chronic schistosomiasis.

Editorial: Immunological aspects of emerging and re-emerging zoonoses.

Dual spike and nucleocapsid mRNA vaccination confer protection against SARS-CoV-2 Omicron and Delta variants in preclinical models.

Differential cellular immune responses against Orientia tsutsugamushi Karp and Gilliam strains following acute infection in mice.

Alterations in germinal center formation and B cell activation during severe Orientia tsutsugamushi infection in mice.

Correction: Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi.

Hepatocyte growth factor in dampening liver immune-mediated pathology in acute viral hepatitis without compromising antiviral activity.

Host transcriptomic profiling of CD-1 outbred mice with severe clinical outcomes following infection with Orientia tsutsugamushi.