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Population Pharmacokinetic Modeling and Simulation for Dose Optimization of GB-5001, a Long-Acting Intramuscular Injection of Donepezil, in Healthy Participants.
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- Neurology & Therapy, 2024, v. 13, n. 5, p. 1453, doi. 10.1007/s40120-024-00643-4
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- Article
An assessment of the pharmacokinetics, pharmacodynamics, and tolerability of GCPGC, a novel pegylated granulocyte colony-stimulating factor (G-CSF), in healthy subjects.
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- Investigational New Drugs, 2014, v. 32, n. 4, p. 636, doi. 10.1007/s10637-014-0068-7
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- Article
Pediatric patients undergoing hematopoietic stem cell transplantation can greatly benefit from a novel once-daily intravenous busulfan dosing nomogram.
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- American Journal of Hematology, 2017, v. 92, n. 7, p. 607, doi. 10.1002/ajh.24734
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- Article
Pharmacokinetic-Pharmacodynamic Relationships of Macitentan, a New Endothelin Receptor Antagonist, After Multiple Dosing in Healthy Korean Subjects.
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- American Journal of Cardiovascular Drugs, 2014, v. 14, n. 5, p. 377, doi. 10.1007/s40256-014-0081-4
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- Article
Antihyperglycemic mechanism of metformin occurs via the AMPK/LXRα/POMC pathway.
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- Scientific Reports, 2015, p. 8145, doi. 10.1038/srep08145
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- Article
Effects of renal impairment on the pharmacokinetics and pharmacodynamics of a novel dipeptidyl peptidase-4 inhibitor, evogliptin ( DA-1229).
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- Diabetes, Obesity & Metabolism, 2017, v. 19, n. 2, p. 294, doi. 10.1111/dom.12813
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- Article
Clinical usefulness of serum cystatin C and the pertinent estimation of glomerular filtration rate based on cystatin C.
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- Nephrology, 2010, v. 15, n. 8, p. 768, doi. 10.1111/j.1440-1797.2010.01344.x
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Changes in Cardiac Function After a Single Intravenous Administration of CKD-712 in Healthy Male Volunteers.
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- Clinical Drug Investigation, 2017, v. 37, n. 4, p. 393, doi. 10.1007/s40261-017-0494-3
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- Article
Successful Empirical Antifungal Therapy of Intravenous Itraconazole with Pharmacokinetic Evidence in Pediatric Cancer Patients Undergoing Hematopoietic Stem Cell Transplantation.
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- Clinical Drug Investigation, 2015, v. 35, n. 7, p. 437, doi. 10.1007/s40261-015-0297-3
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- Article
Tolerability and Pharmacokinetics of Lobeglitazone, a Novel Peroxisome Proliferator-Activated Receptor-γ Agonist, After a Single Oral Administration in Healthy Female Subjects.
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- Clinical Drug Investigation, 2014, v. 34, n. 7, p. 467, doi. 10.1007/s40261-014-0197-y
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- Article
Pharmacodynamics, Pharmacokinetics, and Tolerability of Intravenous or Subcutaneous GC1113, a Novel Erythropoiesis-Stimulating Agent.
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- Clinical Drug Investigation, 2014, v. 34, n. 6, p. 373, doi. 10.1007/s40261-014-0183-4
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- Article
Pharmacokinetic and Pharmacodynamic Interaction Between Gemigliptin and Metformin in Healthy Subjects.
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- Clinical Drug Investigation, 2014, v. 34, n. 6, p. 383, doi. 10.1007/s40261-014-0184-3
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- Article
Relationship Between Absolute Neutrophil Count Profiles and Pharmacokinetics of DA-3031, a Pegylated Granulocyte Colony-Stimulating Factor (Pegylated-G-CSF): A Dose Block-Randomized, Double-Blind, Dose-Escalation Study in Healthy Subjects.
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- Clinical Drug Investigation, 2013, v. 33, n. 11, p. 817, doi. 10.1007/s40261-013-0130-9
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- Article
HL156A, a novel pharmacological agent with potent adenosine-monophosphate-activated protein kinase (AMPK) activator activity ameliorates renal fibrosis in a rat unilateral ureteral obstruction model.
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- PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0201692
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- Article
A non-linear pharmacokinetic-pharmacodynamic relationship of metformin in healthy volunteers: An open-label, parallel group, randomized clinical study.
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- PLoS ONE, 2018, v. 13, n. 1, p. 1, doi. 10.1371/journal.pone.0191258
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- Article
Effect of OATP1B1 (SLCO1B1) variant alleles on the pharmacokinetics of pitavastatin in healthy volunteers
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- Clinical Pharmacology & Therapeutics, 2005, v. 78, n. 4, p. 342, doi. 10.1016/j.clpt.2005.07.003
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- Article
Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers
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- Clinical Pharmacology & Therapeutics, 2005, v. 77, n. 6, p. 486, doi. 10.1016/j.clpt.2005.02.006
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A variant 2677A allele of the MDR1 gene affects fexofenadine disposition<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 5, p. 418, doi. 10.1016/j.clpt.2004.08.002
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- Article
Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 2, p. 104, doi. 10.1016/j.clpt.2004.03.009
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Ethnic differences and relationships in the oral pharmacokinetics of nifedipine and erythromycin<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2001, v. 70, n. 3, p. 228, doi. 10.1067/mcp.2001.117703
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Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19<sup>*</sup>.
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- Clinical Pharmacology & Therapeutics, 2001, v. 69, n. 4, p. 266, doi. 10.1067/mcp.2001.114231
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Assessment of Appropriateness of an Initial Dosing Regimen of Vancomycin and Development of a New Dosing Nomogram.
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- Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 2, p. 233, doi. 10.1111/bcpt.12873
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- Article
The Effect of Genetic Polymorphisms in SLCO2B1 on the Lipid-Lowering Efficacy of Rosuvastatin in Healthy Adults with Elevated Low-Density Lipoprotein.
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- Basic & Clinical Pharmacology & Toxicology, 2017, v. 121, n. 3, p. 195, doi. 10.1111/bcpt.12826
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- Article
Sustained Increase in the Oral Bioavailability of Loperamide after a Single Oral Dose of HM30181, a P-glycoprotein Inhibitor, in Healthy Male Participants.
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- Basic & Clinical Pharmacology & Toxicology, 2013, v. 113, n. 6, p. 419, doi. 10.1111/bcpt.12108
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Pharmacokinetic-Pharmacodynamic Modelling of Biomarker Response to Sitagliptin in Healthy Volunteers.
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- Basic & Clinical Pharmacology & Toxicology, 2013, v. 113, n. 2, p. 113, doi. 10.1111/bcpt.12068
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Assessment of the Analgesic Effect of Remifentanil using Three Pain Models in Healthy Korean Volunteers: A Randomized, Controlled Study.
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- Basic & Clinical Pharmacology & Toxicology, 2012, v. 110, n. 6, p. 518, doi. 10.1111/j.1742-7843.2011.00849.x
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- Article
Ursodeoxycholic acid improves liver function via phenylalanine/tyrosine pathway and microbiome remodelling in patients with liver dysfunction.
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- Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-30349-1
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- Article
URC102, a potent and selective inhibitor of hURAT1, reduced serum uric acid in healthy volunteers.
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- Rheumatology, 2019, v. 58, n. 11, p. 1976, doi. 10.1093/rheumatology/kez140
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- Article
Cytoplasmic zinc promotes IL-1β production by monocytes and macrophages through mTORC1-induced glycolysis in rheumatoid arthritis.
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- Science Signaling, 2022, v. 15, n. 716, p. 1, doi. 10.1126/scisignal.abi7400
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- Article
The Effect of Therapeutic Drug Monitoring on Safety and Efficacy of Voriconazole in Invasive Fungal Infections: A Randomized Controlled Trial.
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- Clinical Infectious Diseases, 2012, v. 55, n. 8, p. 1080, doi. 10.1093/cid/cis599
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Voriconazole-associated severe hyponatremia.
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- Medical Mycology, 2012, v. 50, n. 1, p. 103, doi. 10.3109/13693786.2011.587210
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- Article
Pharmacokinetic Comparison Between a Fixed-Dose Combination of Atorvastatin/Omega-3-Acid Ethyl Esters and the Corresponding Loose Combination in Healthy Korean Male Subjects.
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- Drug Design, Development & Therapy, 2024, v. 18, p. 395, doi. 10.2147/DDDT.S435885
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Comparison of the Pharmacokinetics, Safety, and Tolerability of Two Empagliflozin Formulations in Healthy Korean Subjects.
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- Drug Design, Development & Therapy, 2023, v. 17, p. 2137, doi. 10.2147/DDDT.S409368
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- Article
Development of a Fast Onset Proton Pump Inhibitor: Comparison of Fixed-Dose Combination of Rabeprazole and Sodium Bicarbonate (YPI-011) to the Conventional Enteric-Coated Rabeprazole.
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- Drug Design, Development & Therapy, 2023, v. 17, p. 497, doi. 10.2147/DDDT.S391716
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- Article
Comparative Pharmacokinetics/Pharmacodynamics of Fixed-Dose Combination of Esomeprazole and Calcium Carbonate (AD-206) to the Conventional Esomeprazole.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 5099, doi. 10.2147/DDDT.S341271
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Pharmacokinetics, Tolerability and Pharmacogenetics of DA-8031 After Multiple Ascending Doses in Healthy Male Subjects.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 2375, doi. 10.2147/DDDT.S309763
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Comparison of Pharmacokinetic, Pharmacodynamic and Tolerability Profiles of CKD-11101, Darbepoetin Alfa (NESP<sup>®</sup>) Biosimilar, to Those of NESP<sup>®</sup> After a Single Subcutaneous or Intravenous Administration to Healthy Subjects.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 1735, doi. 10.2147/DDDT.S303772
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- Article
Pharmacokinetic and Pharmacodynamic Comparison of Two Formulations of a Fixed-Dose Combination of Gemigliptin/Rosuvastatin 50/20 mg: A Randomized, Open-Label, Single-Dose, Two-Way Crossover Study.
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- Drug Design, Development & Therapy, 2021, v. 15, p. 651, doi. 10.2147/DDDT.S288986
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- Article
Pharmacokinetic/Pharmacodynamic Interactions Between Evogliptin and Glimepiride in Healthy Male Subjects.
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- Drug Design, Development & Therapy, 2020, v. 14, p. 5179, doi. 10.2147/DDDT.S275343
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- Article
Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and Pioglitazone in Healthy Male Subjects.
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- Drug Design, Development & Therapy, 2020, v. 14, p. 4493, doi. 10.2147/DDDT.S275336
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A Fixed-Dose Combination Of Gemigliptin And Rosuvastatin Exhibits Similar Pharmacokinetics, Pharmacodynamics, And Safety Compared To That Of A Loose Combination In Healthy Subjects.
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- Drug Design, Development & Therapy, 2019, v. 13, p. 3879, doi. 10.2147/DDDT.S197054
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Pharmacokinetics and tolerability of IDP-73152 mesylate after a single oral administration under fasted and fed conditions in healthy volunteers.
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- Drug Design, Development & Therapy, 2019, v. 13, p. 2483, doi. 10.2147/DDDT.S209238
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- Article
Pharmacokinetic interactions between telmisartan/amlodipine and rosuvastatin after multiple oral administrations in healthy Korean male subjects.
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- Drug Design, Development & Therapy, 2019, v. 13, p. 2533, doi. 10.2147/DDDT.S210364
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Pharmacokinetic interaction between fimasartan and atorvastatin in healthy male volunteers.
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- Drug Design, Development & Therapy, 2018, v. 12, p. 2301, doi. 10.2147/DDDT.S165171
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Effect of food on the pharmacokinetic characteristics of a single oral dose of LCB01-0371, a novel oxazolidinone antibiotic.
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- Drug Design, Development & Therapy, 2018, v. 12, p. 1707, doi. 10.2147/DDDT.S155657
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Pharmacokinetic characteristics of telaprevir in healthy Korean male subjects and comparisons with Japanese.
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- Drug Design, Development & Therapy, 2018, v. 12, p. 1045, doi. 10.2147/DDDT.S148117
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Evaluation of drug interactions between fimasartan and rosuvastatin after single and multiple doses in healthy Caucasians.
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- Drug Design, Development & Therapy, 2018, v. 12, p. 787, doi. 10.2147/DDDT.S145339
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Pharmacokinetics and tolerability of eletriptan hydrobromide in healthy Korean subjects.
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- Drug Design, Development & Therapy, 2018, v. 12, p. 331, doi. 10.2147/DDDT.S149119
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Physiologically Based Pharmacokinetic Modeling of Fimasartan, Amlodipine, and Hydrochlorothiazide for the Investigation of Drug-Drug Interaction Potentials.
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- Pharmaceutical Research, 2018, v. 35, n. 12, p. 1, doi. 10.1007/s11095-018-2511-5
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- Article
Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects.
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- European Journal of Clinical Pharmacology, 2018, v. 74, n. 10, p. 1261, doi. 10.1007/s00228-018-2502-9
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- Article