Works matching AU Yu, Kenneth H.


Results: 44
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    Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis.

    Published in:
    Nature, 2011, v. 475, n. 7354, p. 106, doi. 10.1038/nature10189
    By:
    • DeNicola, Gina M.;
    • Karreth, Florian A.;
    • Humpton, Timothy J.;
    • Gopinathan, Aarthi;
    • Cong Wei;
    • Frese, Kristopher;
    • Mangal, Dipti;
    • Yu, Kenneth H.;
    • Yeo, Charles J.;
    • Calhoun, Eric S.;
    • Scrimieri, Francesca;
    • Winter, Jordan M.;
    • Hruban, Ralph H.;
    • Iacobuzio-Donahue, Christine;
    • Kern, Scott E.;
    • Blair, Ian A.;
    • Tuveson, David A.
    Publication type:
    Article
    10

    Use of Machine-Learning Algorithms in Intensified Preoperative Therapy of Pancreatic Cancer to Predict Individual Risk of Relapse.

    Published in:
    Cancers, 2019, v. 11, n. 5, p. 606, doi. 10.3390/cancers11050606
    By:
    • Sala Elarre, Pablo;
    • Oyaga-Iriarte, Esther;
    • Yu, Kenneth H.;
    • Baudin, Vicky;
    • Arbea Moreno, Leire;
    • Carranza, Omar;
    • Chopitea Ortega, Ana;
    • Ponz-Sarvise, Mariano;
    • Mejías Sosa, Luis D.;
    • Rotellar Sastre, Fernando;
    • Larrea Leoz, Blanca;
    • Iragorri Barberena, Yohana;
    • Subtil Iñigo, Jose C.;
    • Benito Boíllos, Alberto;
    • Pardo, Fernando;
    • Rodríguez Rodríguez, Javier
    Publication type:
    Article
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    Circulating tumor and invasive cell expression profiling predicts effective therapy in pancreatic cancer.

    Published in:
    Cancer (0008543X), 2022, v. 128, n. 15, p. 2958, doi. 10.1002/cncr.34269
    By:
    • Yu, Kenneth H.;
    • Park, Jennifer;
    • Mittal, Avni;
    • Abou‐Alfa, Ghassan K.;
    • El Dika, Imane;
    • Epstein, Andrew S.;
    • Ilson, David H.;
    • Kelsen, David P.;
    • Ku, Geoffrey Y.;
    • Li, Jia;
    • Park, Wungki;
    • Varghese, Anna M.;
    • Chou, Joanne F‐L;
    • Capanu, Marinela;
    • Cooper, Brandon;
    • Bartlett, Andrew;
    • McCarthy, Devan;
    • Sangar, Vineet;
    • McCarthy, Brian;
    • O'Reilly, Eileen M.
    Publication type:
    Article
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    Pancreas cancer and BRCA: A critical subset of patients with improving therapeutic outcomes.

    Published in:
    Cancer (0008543X), 2021, v. 127, n. 23, p. 4393, doi. 10.1002/cncr.33812
    By:
    • Momtaz, Parisa;
    • O'Connor, Catherine A.;
    • Chou, Joanne F.;
    • Capanu, Marinela;
    • Park, Wungki;
    • Bandlamudi, Chaitanya;
    • Berger, Michael F.;
    • Kelsen, David P.;
    • Suehnholz, Sarah P.;
    • Chakravarty, Debyani;
    • Yu, Kenneth H.;
    • Varghese, Anna M.;
    • Zervoudakis, Alice;
    • Li, Jia;
    • Ku, Geoffrey Y.;
    • Park, Jennifer S.;
    • Shcherba, Marina;
    • Harding, James J.;
    • Goldberg, Zoe;
    • Abou‐Alfa, Ghassan K.
    Publication type:
    Article
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    Alterations in driver genes are predictive of survival in patients with resected pancreatic ductal adenocarcinoma.

    Published in:
    2020
    By:
    • McIntyre, Caitlin A.;
    • Lawrence, Sharon A.;
    • Richards, Allison L.;
    • Chou, Joanne F.;
    • Wong, Winston;
    • Capanu, Marinela;
    • Berger, Michael F.;
    • Donoghue, Mark T. A.;
    • Yu, Kenneth H.;
    • Varghese, Anna M.;
    • Kelsen, David P.;
    • Park, Wungki;
    • Balachandran, Vinod P.;
    • Kingham, T. Peter;
    • D'Angelica, Michael I.;
    • Drebin, Jeffrey A.;
    • Jarnagin, William R.;
    • Iacobuzio‐Donahue, Christine A.;
    • Allen, Peter J.;
    • O'Reilly, Eileen M.
    Publication type:
    journal article
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    Ampullary cancer: Evaluation of somatic and germline genetic alterations and association with clinical outcomes.

    Published in:
    2019
    By:
    • Wong, Winston;
    • Lowery, Maeve A.;
    • Berger, Michael F.;
    • Kemel, Yelena;
    • Taylor, Barry;
    • Zehir, Ahmet;
    • Srinivasan, Preethi;
    • Bandlamudi, Chaitanya;
    • Chou, Joanne;
    • Capanu, Marinela;
    • Varghese, Anna;
    • Yu, Kenneth H.;
    • Iacobuzio‐Donahue, Christine A.;
    • Shia, Jinru;
    • Klimstra, David S.;
    • Jarnagin, William R.;
    • Stadler, Zsofia K.;
    • O'Reilly, Eileen M.;
    • Iacobuzio-Donahue, Christine A
    Publication type:
    journal article
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    Phase 1 trial evaluating cisplatin, gemcitabine, and veliparib in 2 patient cohorts: Germline BRCA mutation carriers and wild-type BRCA pancreatic ductal adenocarcinoma.

    Published in:
    2018
    By:
    • O'Reilly, Eileen M.;
    • Lee, Jonathan W.;
    • Lowery, Maeve A.;
    • Capanu, Marinela;
    • Stadler, Zsofia K.;
    • Moore, Malcolm J.;
    • Dhani, Neesha;
    • Kindler, Hedy L.;
    • Estrella, Hayley;
    • Maynard, Hannah;
    • Golan, Talia;
    • Segal, Amiel;
    • Salo‐Mullen, Erin E.;
    • Yu, Kenneth H.;
    • Epstein, Andrew S.;
    • Segal, Michal;
    • Brenner, Robin;
    • Do, Richard K.;
    • Chen, Alice P.;
    • Tang, Laura H.
    Publication type:
    journal article
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    A phase 1/1B trial of ADI-PEG 20 plus nab-paclitaxel and gemcitabine in patients with advanced pancreatic adenocarcinoma.

    Published in:
    2017
    By:
    • Lowery, Maeve A.;
    • Yu, Kenneth H.;
    • Kelsen, David Paul;
    • Harding, James J.;
    • Bomalaski, John S.;
    • Glassman, Danielle C.;
    • Covington, Christina M.;
    • Brenner, Robin;
    • Hollywood, Ellen;
    • Barba, Adalberto;
    • Johnston, Amanda;
    • Liu, Kay Chia‐Wei;
    • Feng, Xiaoxing;
    • Capanu, Marinela;
    • Abou‐Alfa, Ghassan K.;
    • O'Reilly, Eileen M.;
    • Liu, Kay Chia-Wei;
    • Abou-Alfa, Ghassan K
    Publication type:
    journal article
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    Identification of germline genetic mutations in patients with pancreatic cancer.

    Published in:
    2015
    By:
    • Salo‐Mullen, Erin E.;
    • O'Reilly, Eileen M.;
    • Kelsen, David P.;
    • Ashraf, Asad M.;
    • Lowery, Maeve A.;
    • Yu, Kenneth H.;
    • Reidy, Diane L.;
    • Epstein, Andrew S.;
    • Lincoln, Anne;
    • Saldia, Amethyst;
    • Jacobs, Lauren M.;
    • Rau‐Murthy, Rohini;
    • Zhang, Liying;
    • Kurtz, Robert C.;
    • Saltz, Leonard;
    • Offit, Kenneth;
    • Robson, Mark E.;
    • Stadler, Zsofia K.
    Publication type:
    journal article
    20

    Induction FOLFIRINOX for patients with locally unresectable pancreatic ductal adenocarcinoma.

    Published in:
    Journal of Surgical Oncology, 2022, v. 125, n. 3, p. 425, doi. 10.1002/jso.26735
    By:
    • McIntyre, Caitlin A.;
    • Cohen, Noah A.;
    • Goldman, Debra A.;
    • Gonen, Mithat;
    • Sadot, Eran;
    • O'Reilly, Eileen M.;
    • Varghese, Anna M.;
    • Yu, Kenneth H.;
    • Balachandran, Vinod P.;
    • Soares, Kevin C.;
    • D'Angelica, Michael I.;
    • Drebin, Jeffrey A.;
    • Kingham, T. P.;
    • Allen, Peter J.;
    • Wei, Alice C.;
    • Jarnagin, William R.
    Publication type:
    Article
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    A randomized phase II trial of nab‐paclitaxel and gemcitabine with tarextumab or placebo in patients with untreated metastatic pancreatic cancer.

    Published in:
    Cancer Medicine, 2019, v. 8, n. 11, p. 5148, doi. 10.1002/cam4.2425
    By:
    • Hu, Zishuo Ian;
    • Bendell, Johanna C.;
    • Bullock, Andrea;
    • LoConte, Noelle K.;
    • Hatoum, Hassan;
    • Ritch, Paul;
    • Hool, Hugo;
    • Leach, Joseph W.;
    • Sanchez, James;
    • Sohal, Davendra P. S.;
    • Strickler, John;
    • Patel, Ravindranath;
    • Wang‐Gillam, Andrea;
    • Firdaus, Irfan;
    • Yu, Kenneth H.;
    • Kapoun, Ann M.;
    • Holmgren, Eric;
    • Zhou, Lei;
    • Dupont, Jakob;
    • Picozzi, Vincent
    Publication type:
    Article
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    A Randomized Controlled Trial of a Cardiopulmonary Resuscitation Video in Advance Care Planning for Progressive Pancreas and Hepatobiliary Cancer Patients.

    Published in:
    Journal of Palliative Medicine, 2013, v. 16, n. 6, p. 623, doi. 10.1089/jpm.2012.0524
    By:
    • Epstein, Andrew S.;
    • Volandes, Angelo E.;
    • Chen, Ling Y.;
    • Gary, Kristen A.;
    • Li, Yuelin;
    • Agre, Patricia;
    • Levin, Tomer T.;
    • Reidy, Diane L.;
    • Meng, Raymond D.;
    • Segal, Neil H.;
    • Yu, Kenneth H.;
    • Abou-Alfa, Ghassan K.;
    • Janjigian, Yelena Y.;
    • Kelsen, David P.;
    • O'reilly, Eileen M.
    Publication type:
    Article
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    Salvage Ablative Radiotherapy for Isolated Local Recurrence of Pancreatic Adenocarcinoma following Definitive Surgery.

    Published in:
    Journal of Clinical Medicine, 2024, v. 13, n. 9, p. 2631, doi. 10.3390/jcm13092631
    By:
    • Dee, Edward Christopher;
    • Ng, Victor C.;
    • O'Reilly, Eileen M.;
    • Wei, Alice C.;
    • Lobaugh, Stephanie M.;
    • Varghese, Anna M.;
    • Zinovoy, Melissa;
    • Romesser, Paul B.;
    • Wu, Abraham J.;
    • Hajj, Carla;
    • Cuaron, John J.;
    • Khalil, Danny N.;
    • Park, Wungki;
    • Yu, Kenneth H.;
    • Zhang, Zhigang;
    • Drebin, Jeffrey A.;
    • Jarnagin, William R.;
    • Crane, Christopher H.;
    • Reyngold, Marsha
    Publication type:
    Article
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    Methylation Analyses Reveal Promoter Hypermethylation as a Rare Cause of "Second Hit" in Germline BRCA1-Associated Pancreatic Ductal Adenocarcinoma.

    Published in:
    Molecular Diagnosis & Therapy, 2022, v. 26, n. 6, p. 645, doi. 10.1007/s40291-022-00614-1
    By:
    • Zheng-Lin, Binbin;
    • Rainone, Michael;
    • Varghese, Anna M.;
    • Yu, Kenneth H.;
    • Park, Wungki;
    • Berger, Michael;
    • Mehine, Miika;
    • Chou, Joanne;
    • Capanu, Marinela;
    • Mandelker, Diana;
    • Stadler, Zsofia K.;
    • Birsoy, Ozge;
    • Jairam, Sowmya;
    • Yang, Ciyu;
    • Li, Yirong;
    • Wong, Donna;
    • Benhamida, Jamal K;
    • Ladanyi, Marc;
    • Zhang, Liying;
    • O'Reilly, Eileen M.
    Publication type:
    Article
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    Ruxolitinib + capecitabine in advanced/metastatic pancreatic cancer after disease progression/intolerance to first-line therapy: JANUS 1 and 2 randomized phase III studies.

    Published in:
    Investigational New Drugs, 2018, v. 36, n. 4, p. 683, doi. 10.1007/s10637-018-0580-2
    By:
    • Hurwitz, Herbert;
    • Van Cutsem, Eric;
    • Bendell, Johanna;
    • Hidalgo, Manuel;
    • Li, Chung-Pin;
    • Salvo, Marcelo Garrido;
    • Macarulla, Teresa;
    • Sahai, Vaibhav;
    • Sama, Ashwin;
    • Greeno, Edward;
    • Yu, Kenneth H.;
    • Verslype, Chris;
    • Dawkins, Fitzroy;
    • Walker, Chris;
    • Clark, Jason;
    • O’Reilly, Eileen M.
    Publication type:
    Article
    42

    Precision medicine for pancreatic cancer: characterizing the clinicogenomic landscape and outcomes of KRAS G12C-mutated disease.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2024, v. 116, n. 9, p. 1429, doi. 10.1093/jnci/djae095
    By:
    • Keane, Fergus;
    • Chou, Joanne F;
    • Walch, Henry;
    • Schoenfeld, Joshua;
    • Singhal, Anupriya;
    • Cowzer, Darren;
    • Harrold, Emily;
    • O'Connor, Catherine A;
    • Park, Wungki;
    • Varghese, Anna;
    • Dika, Imane El;
    • Balogun, Fiyinfolu;
    • Yu, Kenneth H;
    • Capanu, Marinela;
    • Schultz, Nikolaus;
    • Yaeger, Rona;
    • O'Reilly, Eileen M
    Publication type:
    Article
    43

    Early-Onset Pancreas Cancer: Clinical Descriptors, Genomics, and Outcomes.

    Published in:
    2021
    By:
    • Varghese, Anna M;
    • Singh, Isha;
    • Singh, Rituraj;
    • Kunte, Siddharth;
    • Chou, Joanne F;
    • Capanu, Marinela;
    • Wong, Winston;
    • Lowery, Maeve A;
    • Stadler, Zsofia K;
    • Salo-Mullen, Erin;
    • Saadat, Lily V;
    • Wei, Alice C;
    • Reyngold, Marsha;
    • Basturk, Olca;
    • Benayed, Ryma;
    • Mandelker, Diana;
    • Iacobuzio-Donahue, Christine A;
    • Kelsen, David P;
    • Park, Wungki;
    • Yu, Kenneth H
    Publication type:
    journal article
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    Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms.

    Published in:
    2018
    By:
    • Lowery, Maeve A;
    • Berger, Michael F;
    • Wong, Winston;
    • Jordan, Emmet J;
    • Lee, Jonathan W;
    • Tjan, Catherine;
    • Covington, Christina;
    • Maynard, Hannah;
    • Hyman, David M;
    • Robson, Mark E;
    • Offit, Kenneth;
    • Stadler, Zsofia K;
    • Brenner, Robin;
    • Kaufmann, Erica;
    • Yu, Kenneth H;
    • Varghese, Anna M;
    • Kelsen, David P;
    • O'Reilly, Eileen M;
    • Abou-Alfa, Ghassan K;
    • Kemel, Yelena
    Publication type:
    journal article