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Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.
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- Nature Medicine, 2013, v. 19, n. 8, p. 1039, doi. 10.1038/nm.3213
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Systems Cell Biology Knowledge Created fromHigh Content Screening.
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- Assay & Drug Development Technologies, 2005, v. 3, n. 5, p. 501
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- Article
Antidiabetic actions of a non-agonist PPAR? ligand blocking Cdk5-mediated phosphorylation.
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- Nature, 2011, v. 477, n. 7365, p. 477, doi. 10.1038/nature10383
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Confirmation of a linkage between H-Ras and MMP-13 expression as well as MMP-9 by chemical genomic approach.
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- International Journal of Cancer, 2006, v. 118, n. 9, p. 2172, doi. 10.1002/ijc.21610
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Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour.
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- Nature Communications, 2014, v. 5, n. 12, p. 5759, doi. 10.1038/ncomms6759
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An alternate binding site for PPARγ ligands.
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- Nature Communications, 2014, v. 5, n. 4, p. 3571, doi. 10.1038/ncomms4571
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Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute ConfigurationsWe thank the National Institutes of Health for funding this work, Y.S. thanks the University of Pittsburgh for a Graduate Excellence Fellowship, J.H.F. thanks FCAR, and A.M.B. thanks the German Academic Exchange Service (DAAD) for postdoctoral fellowships. We also thank Professor Billy Day for helpful discussions, Dr. Cherry Herald for spectra of dictyostatin, Dr. Amy Wright for permission to compare samples, and Prof. Ian Paterson for comparing the samples and kindly agreeing to joint publication.
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- Angewandte Chemie, 2004, v. 116, n. 35, p. 4734, doi. 10.1002/ange.200460593
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Titelbild: Total Synthesis and Configurational Assignment of (−)-Dictyostatin, a Microtubule-Stabilizing Macrolide of Marine Sponge Origin / Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations (Angew....
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- Angewandte Chemie, 2004, v. 116, n. 35, p. 4637, doi. 10.1002/ange.200490121
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Regulation of circadian behaviour and metabolism by synthetic REV-ERB agonists.
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- Nature, 2012, v. 485, n. 7396, p. 62, doi. 10.1038/nature11030
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Defining a conformational ensemble that directs activation of PPARγ.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04176-x
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Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute ConfigurationsWe thank the National Institutes of Health for funding this work, Y.S. thanks the University of Pittsburgh for a Graduate Excellence Fellowship, J.H.F. thanks FCAR, and A.M.B. thanks the German Academic Exchange Service (DAAD) for postdoctoral fellowships. We also thank Professor Billy Day for helpful discussions, Dr. Cherry Herald for spectra of dictyostatin, Dr. Amy Wright for permission to compare samples, and Prof. Ian Paterson for comparing the samples and kindly agreeing to joint publication.
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- Angewandte Chemie International Edition, 2004, v. 43, n. 35, p. 4634, doi. 10.1002/anie.200460593
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- Article
Cover Picture: Total Synthesis and Configurational Assignment of (−)-Dictyostatin, a Microtubule-Stabilizing Macrolide of Marine Sponge Origin / Total Synthesis of (−)-Dictyostatin: Confirmation of Relative and Absolute Configurations (Angew. Chem. Int. Ed. 35/2004)
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- Angewandte Chemie International Edition, 2004, v. 43, n. 35, p. 4537, doi. 10.1002/anie.200490122
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- Article