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Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32701-6
By:
- Westbrook, Thomas C.;
- Guan, Xiangnan;
- Rodansky, Eva;
- Flores, Diana;
- Liu, Chia Jen;
- Udager, Aaron M.;
- Patel, Radhika A.;
- Haffner, Michael C.;
- Hu, Ya-Mei;
- Sun, Duanchen;
- Beer, Tomasz M.;
- Foye, Adam;
- Aggarwal, Rahul;
- Quigley, David A.;
- Youngren, Jack F.;
- Ryan, Charles J.;
- Gleave, Martin;
- Wang, Yuzhuo;
- Huang, Jiaoti;
- Coleman, Ilsa
Publication type:
Article
Insulin Resistance Induced by Hyperinsulinemia Coincides with a Persistent Alteration at the Insulin Receptor Tyrosine Kinase Domain.
Published in:
PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0108693
By:
- Catalano, Karyn J.;
- Maddux, Betty A.;
- Szary, Jaroslaw;
- Youngren, Jack F.;
- Goldfine, Ira D.;
- Schaufele, Fred
Publication type:
Article
Insulin Resistance in Non-Obese Subjects Is Associated with Activation of the JNK Pathway and Impaired Insulin Signaling in Skeletal Muscle.
Published in:
PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0019878
By:
- Masharani, Umesh B.;
- Maddux, Betty A.;
- Xiaojuan Li;
- Sakkas, Giorgos K.;
- Mulligan, Kathleen;
- Schambelan, Morris;
- Goldfine, Ira D.;
- Youngren, Jack F.
Publication type:
Article
Role of PC-1 in The Etiology of Insulin Resistance.
Published in:
Annals of the New York Academy of Sciences, 1999, v. 892, n. 1, p. 204, doi. 10.1111/j.1749-6632.1999.tb07797.x
By:
- GOLDFINE, IRA D.;
- MADDUX, BETTY A.;
- YOUNGREN, JACK F.;
- TRISCHITTA, VINCENZO;
- FRITTITTA, LUCIA
Publication type:
Article
Nordihydroguaiaretic acid (NDGA), an inhibitor of the HER2 and IGF-1 receptor tyrosine kinases, blocks the growth of HER2-overexpressing human breast cancer cells.
Published in:
Journal of Cellular Biochemistry, 2008, v. 103, n. 2, p. 624, doi. 10.1002/jcb.21435
By:
- Zavodovskaya, Marianna;
- Campbell, Michael J.;
- Maddux, Betty A.;
- Shiry, Laura;
- Allan, Geoffrey;
- Hodges, Leslie;
- Kushner, Peter;
- Kerner, John A.;
- Youngren, Jack F.;
- Goldfine, Ira D.
Publication type:
Article
Nordihydroguaiaretic acid inhibits insulin-like growth factor signaling, growth, and survival in human neuroblastoma cells.
Published in:
Journal of Cellular Biochemistry, 2007, v. 102, n. 6, p. 1529, doi. 10.1002/jcb.21373
By:
- Meyer, Gary E.;
- Chesler, Louis;
- Liu, Dandan;
- Gable, Karissa;
- Maddux, Betty A.;
- Goldenberg, David D.;
- Youngren, Jack F.;
- Goldfine, Ira D.;
- Weiss, William A.;
- Matthay, Katherine K.;
- Rosenthal, Stephen M.
Publication type:
Article
Expression of genes regulating Malonyl-CoA in human skeletal muscle.
Published in:
Journal of Cellular Biochemistry, 2006, v. 99, n. 3, p. 860, doi. 10.1002/jcb.20944
By:
- Pender, Celia;
- Trentadue, Anna R.;
- Pories, Walter J.;
- Dohm, G. Lynis;
- Houmard, Joseph A.;
- Youngren, Jack F.
Publication type:
Article
Inhibitory effects of nordihydroguaiaretic acid (NDGA) on the IGF-1 receptor and androgen dependent growth of LAPC-4 prostate cancer cells.
Published in:
Prostate, 2008, v. 68, n. 11, p. 1232, doi. 10.1002/pros.20789
By:
- Ryan, Charles J.;
- Zavodovskaya, Marianna;
- Youngren, Jack F.;
- Campbell, Michael;
- Diamond, Marc;
- Jones, Jeremy;
- Shiry, Laura;
- Allan, Geoffrey;
- Maddux, Betty A.;
- Goldfine, Ira D.
Publication type:
Article
Increased hepatic levels of the insulin receptor inhibitor, PC-1/NPP1, induce insulin resistance and glucose intolerance.
Published in:
2005
By:
- Dong, Hengjiang;
- Maddux, Betty A.;
- Altomonte, Jennifer;
- Meseck, Marcia;
- Accili, Domenico;
- Terkeltaub, Robert;
- Johnson, Kristen;
- Youngren, Jack F.;
- Goldfine, Ira D.
Publication type:
journal article
Plasma adiponectin concentration is associated with skeletal muscle insulin receptor tyrosine phosphorylation, and low plasma concentration precedes a decrease in whole-body insulin sensitivity in humans.
Published in:
2002
By:
- Stefan, Norbert;
- Vozarova, Barbora;
- Funahashi, Tohru;
- Matsuzawa, Yuji;
- Weyer, Christian;
- Lindsay, Robert S.;
- Youngren, Jack F.;
- Havel, Peter J.;
- Pratley, Richard E.;
- Bogardus, Clifton;
- Tataranni, P. Antonio
Publication type:
journal article
Small molecule insulin receptor activators potentiate insulin action in insulin-resistant cells.
Published in:
2001
By:
- Li, Ming;
- Youngren, Jack F.;
- Manchem, Vara Prasad;
- Kozlowski, Michael;
- Zhang, Bei B.;
- Maddux, Betty A.;
- Goldfine, Ira D.;
- Li, M;
- Youngren, J F;
- Manchem, V P;
- Kozlowski, M;
- Zhang, B B;
- Maddux, B A;
- Goldfine, I D
Publication type:
journal article
Chromium supplementation in non-obese non-diabetic subjects is associated with a decline in insulin sensitivity.
Published in:
BMC Endocrine Disorders, 2012, v. 12, n. 1, p. 31, doi. 10.1186/1472-6823-12-31
By:
- Masharani, Umesh;
- Gjerde, Christine;
- McCoy, Shelley;
- Maddux, Betty A.;
- Hessler, Danielle;
- Goldfine, Ira D.;
- Youngren, Jack F.
Publication type:
Article
Diet, not aging, causes skeletal muscle insulin resistance.
Published in:
1995
By:
- Barnard, James;
- Youngren, Jack F.;
- Martin, Deborah A.;
- Barnard, R J;
- Youngren, J F;
- Martin, D A
Publication type:
journal article

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