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A sporadic Parkinson's disease model via silencing of the ubiquitin–proteasome/E3 ligase component, SKP1A.
- Published in:
- Journal of Neural Transmission, 2024, v. 131, n. 6, p. 675, doi. 10.1007/s00702-023-02687-6
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- Article
Correction to: Lithium's Gene Expression Profile, Relevance to Neuroprotection A cDNA Microarray Study.
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- 2023
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- Publication type:
- Correction Notice
Lewy bodies, iron, inflammation and neuromelanin: pathological aspects underlying Parkinson's disease.
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- Journal of Neural Transmission, 2023, v. 130, n. 5, p. 627, doi. 10.1007/s00702-023-02630-9
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- Publication type:
- Article
The Neuroprotective Activities of the Novel Multi-Target Iron-Chelators in Models of Alzheimer's Disease, Amyotrophic Lateral Sclerosis and Aging.
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- Cells (2073-4409), 2023, v. 12, n. 5, p. 763, doi. 10.3390/cells12050763
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- Publication type:
- Article
Treatment; Moussa B.H. Youdim.
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- Journal of Neural Transmission, 2022, v. 129, n. 5/6, p. 713, doi. 10.1007/s00702-022-02492-7
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- Publication type:
- Article
Site-activated multi target iron chelators with acetylcholinesterase (AChE) and monoamine oxidase (MAO) inhibitory activities for Alzheimer's disease therapy.
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- Journal of Neural Transmission, 2022, v. 129, n. 5/6, p. 715, doi. 10.1007/s00702-022-02462-z
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- Publication type:
- Article
Creation of a gene expression classifier for predicting Parkinson's disease rate of progression.
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- Journal of Neural Transmission, 2020, v. 127, n. 5, p. 755, doi. 10.1007/s00702-020-02194-y
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- Article
Selegiline: a molecule with innovative potential.
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- Journal of Neural Transmission, 2020, v. 127, n. 5, p. 831, doi. 10.1007/s00702-019-02082-0
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- Publication type:
- Article
Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases.
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- Journal of Neural Transmission, 2018, v. 125, n. 11, p. 1719, doi. 10.1007/s00702-018-1942-9
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- Publication type:
- Article
Monoamine oxidase A upregulated by chronic intermittent hypoxia activates indoleamine 2,3-dioxygenase and neurodegeneration.
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- PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177940
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- Publication type:
- Article
M30 Antagonizes Indoleamine 2,3-Dioxygenase Activation and Neurodegeneration Induced by Corticosterone in the Hippocampus.
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- PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0166966
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- Publication type:
- Article
Neuroprotective effects of multifaceted hybrid agents targeting MAO, cholinesterase, iron and β-amyloid in ageing and Alzheimer's disease.
- Published in:
- 2016
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- Publication type:
- journal article
Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease.
- Published in:
- Frontiers in Neuroscience, 2016, p. 1, doi. 10.3389/fnins.2016.00205
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- Publication type:
- Article
A Novel Antioxidant Multitarget Iron Chelator M30 Protects Hepatocytes against Ethanol-Induced Injury.
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- Oxidative Medicine & Cellular Longevity, 2015, v. 2015, p. 1, doi. 10.1155/2015/607271
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- Publication type:
- Article
Molecular targets of the multifunctional iron-chelating drug, M30, in the brains of mouse models of type 2 diabetes mellitus.
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- British Journal of Pharmacology, 2014, v. 171, n. 24, p. 5636, doi. 10.1111/bph.12862
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- Publication type:
- Article
DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline.
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- Journal of Neurochemistry, 2014, v. 129, n. 3, p. 434, doi. 10.1111/jnc.12633
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- Article
I<sub>1</sub> Imidazoline Receptor: Novel Potential Cytoprotective Target of TVP1022, the S-Enantiomer of Rasagiline.
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- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0047890
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- Publication type:
- Article
Neuroprotection and Neuroregeneration in Alzheimer's Disease.
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- International Journal of Alzheimer's Disease, 2012, p. 1, doi. 10.1155/2012/864138
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- Publication type:
- Article
Neuroprotection and Neuroregeneration in Alzheimer's Disease.
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- 2012
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- Publication type:
- Journal Article
A molecular signature in blood identifies early Parkinson's disease.
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- Molecular Neurodegeneration, 2012, v. 7, n. 1, p. 26, doi. 10.1186/1750-1326-7-26
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- Publication type:
- Article
The relevance of iron in the pathogenesis of Parkinson's disease.
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- Journal of Neurochemistry, 2011, v. 118, n. 6, p. 939, doi. 10.1111/j.1471-4159.2010.07132.x
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- Publication type:
- Article
The involvement of GABAA receptor in the molecular mechanisms of combined selective serotonin reuptake inhibitor-antipsychotic treatment.
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- International Journal of Neuropsychopharmacology, 2011, v. 14, n. 2, p. 143, doi. 10.1017/S1461145710000106
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- Publication type:
- Article
PGC-1α, A Potential Therapeutic Target for Early Intervention in Parkinson's Disease.
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- Science Translational Medicine, 2010, v. 2, n. 52, p. 1, doi. 10.1126/scitranslmed.3001059
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- Publication type:
- Article
Propargylamine Containing Compounds as Modulators of Proteolytic Cleavage of Amyloid Protein Precursor: Involvement of MAPK and PKC Activation.
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- Journal of Alzheimer's Disease, 2010, v. 21, n. 2, p. 361, doi. 10.3233/JAD-2010-100150
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- Publication type:
- Article
Limited Potentiation of Blood Pressure in Response to Oral Tyramine by the Anti-Parkinson Brain Selective Multifunctional Monoamine Oxidase-AB Inhibitor, M30.
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- Neurotoxicity Research, 2010, v. 18, n. 2, p. 143, doi. 10.1007/s12640-009-9128-8
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- Publication type:
- Article
Metallocorroles as cytoprotective agents against oxidative and nitrative stress in cellular models of neurodegeneration.
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- Journal of Neurochemistry, 2010, v. 113, n. 2, p. 363, doi. 10.1111/j.1471-4159.2010.06619.x
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- Publication type:
- Article
Silencing/Overexpressing Selected Genes as a Model of Sporadic Parkinson’s Disease.
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- Neurodegenerative Diseases, 2010, v. 7, n. 1-3, p. 108, doi. 10.1159/000285517
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- Publication type:
- Article
The neuroprotective mechanism of 1-( R)-aminoindan, the major metabolite of the anti-parkinsonian drug rasagiline.
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- Journal of Neurochemistry, 2010, v. 112, n. 5, p. 1131, doi. 10.1111/j.1471-4159.2009.06542.x
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- Publication type:
- Article
Restoration of Nigrostriatal Dopamine Neurons in Post-MPTP Treatment by the Novel Multifunctional Brain-Permeable Iron Chelator-Monoamine Oxidase Inhibitor Drug, M30.
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- Neurotoxicity Research, 2010, v. 17, n. 1, p. 15, doi. 10.1007/s12640-009-9070-9
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- Publication type:
- Article
Neuroprotective and neuritogenic activities of novel multimodal iron-chelating drugs in motor-neuron-like NSC-34 cells and transgenic mouse model of amyotrophic lateral sclerosis.
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- FASEB Journal, 2009, v. 23, n. 11, p. 3766, doi. 10.1096/fj.09-130047
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- Publication type:
- Article
Preface.
- Published in:
- 2009
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- Publication type:
- Editorial
Genomic and proteomic study to survey the mechanism of action of the anti-Parkinson’s disease drug, rasagiline compared with selegiline, in the rat midbrain.
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- Journal of Neural Transmission, 2009, v. 116, n. 11, p. 1457, doi. 10.1007/s00702-009-0225-x
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- Publication type:
- Article
Molecular mechanisms underlying synergistic effects of SSRI–antipsychotic augmentation in treatment of negative symptoms in schizophrenia.
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- Journal of Neural Transmission, 2009, v. 116, n. 11, p. 1529, doi. 10.1007/s00702-009-0255-4
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- Publication type:
- Article
Glyceraldehyde-3-Phosphate Dehydrogenase–Monoamine Oxidase B-Mediated Cell Death-Induced by Ethanol is Prevented by Rasagiline and 1-R-Aminoindan.
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- Neurotoxicity Research, 2009, v. 16, n. 2, p. 148, doi. 10.1007/s12640-009-9064-7
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- Publication type:
- Article
Comparative Neuroprotective Effects of Rasagiline and Aminoindan with Selegiline on Dexamethasone-Induced Brain Cell Apoptosis.
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- Neurotoxicity Research, 2009, v. 15, n. 3, p. 284, doi. 10.1007/s12640-009-9030-4
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- Publication type:
- Article
Comparitive neuroprotective effects of rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis.
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- Neurotoxicity Research, 2009, v. 15, n. 1, p. 1
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- Publication type:
- Article
Simultaneous Manipulation of Multiple Brain Targets by Green Tea Catechins: A Potential Neuroprotective Strategy for Alzheimer and Parkinson Diseases.
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- CNS Neuroscience & Therapeutics, 2008, v. 14, n. 4, p. 352, doi. 10.1111/j.1755-5949.2008.00060.x
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- Publication type:
- Article
Cell signaling pathways and iron chelation in the neurorestorative activity of green tea polyphenols: special reference to epigallocatechin gallate (EGCG).
- Published in:
- 2008
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- Publication type:
- journal article
Cell Signaling Pathways and Iron Chelation in the Neurorestorative Activity of Green Tea Polyphenols: Special Reference to Epigallocatechin Gallate (EGCG).
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- Journal of Alzheimer's Disease, 2008, v. 15, n. 2, p. 211, doi. 10.3233/JAD-2008-15207
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- Publication type:
- Article
Comparison of neuroprotective and neurorestorative capabilities of rasagiline and selegiline against lactacystin-induced nigrostriatal dopaminergic degeneration.
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- Journal of Neurochemistry, 2008, v. 105, n. 5, p. 1970, doi. 10.1111/j.1471-4159.2008.05330.x
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- Publication type:
- Article
Brain Iron Deficiency and Excess; Cognitive Impairment and Neurodegenration with Involvement of Striatum and Hippocampus.
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- Neurotoxicity Research, 2008, v. 14, n. 1, p. 45, doi. 10.1007/BF03033574
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- Publication type:
- Article
Targeting multiple Alzheimer's disease etiologies with multimodal neuroprotective and neurorestorative iron chelators.
- Published in:
- FASEB Journal, 2008, v. 22, n. 5, p. 1296, doi. 10.1096/fj.07-8627rev
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- Publication type:
- Article
Physiological and pathological aspects of Aβ in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators.
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- BMC Neuroscience, 2008, v. 9, p. 1, doi. 10.1186/1471-2202-9-S2-S2
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- Publication type:
- Article
Physiological and pathological aspects of Abeta in iron homeostasis via 5'UTR in the APP mRNA and the therapeutic use of iron-chelators.
- Published in:
- 2008
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- Publication type:
- journal article
Prevention and restoration of lactacystin-induced nigrostriatal dopamine neuron degeneration by novel brain-permeable iron chelators.
- Published in:
- FASEB Journal, 2007, v. 21, n. 14, p. 3835, doi. 10.1096/fj.07-8386com
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- Publication type:
- Article
The neuroprotective effect of Activin A and B: implication for neurodegenerative diseases.
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- Journal of Neurochemistry, 2007, v. 103, n. 3, p. 962, doi. 10.1111/j.1471-4159.2007.04785.x
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- Publication type:
- Article
Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro.
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- Journal of Neurochemistry, 2007, v. 103, n. 2, p. 500, doi. 10.1111/j.1471-4159.2007.04777.x
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- Publication type:
- Article
Magic bullets or novel multimodal drugs with various CNS targets for Parkinson's disease?
- Published in:
- 2007
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- Publication type:
- Letter
Green tea polyphenol (–)-epigallocatechin-3-gallate promotes the rapid protein kinase C- and proteasome-mediated degradation of Bad: implications for neuroprotection.
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- Journal of Neurochemistry, 2007, v. 100, n. 4, p. 992, doi. 10.1111/j.1471-4159.2006.04265.x
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- Publication type:
- Article
Therapeutic targets and potential of the novel brain- permeable multifunctional iron chelator–monoamine oxidase inhibitor drug, M-30, for the treatment of Alzheimer's disease.
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- Journal of Neurochemistry, 2007, v. 100, n. 2, p. 490, doi. 10.1111/j.1471-4159.2006.04258.x
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- Publication type:
- Article