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Single-nucleus RNA-sequencing of autosomal dominant Alzheimer disease and risk variant carriers.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37437-5
By:
- Brase, Logan;
- You, Shih-Feng;
- D'Oliveira Albanus, Ricardo;
- Del-Aguila, Jorge L.;
- Dai, Yaoyi;
- Novotny, Brenna C.;
- Soriano-Tarraga, Carolina;
- Dykstra, Taitea;
- Fernandez, Maria Victoria;
- Budde, John P.;
- Bergmann, Kristy;
- Morris, John C.;
- Bateman, Randall J.;
- Perrin, Richard J.;
- McDade, Eric;
- Xiong, Chengjie;
- Goate, Alison M.;
- Farlow, Martin;
- Sutherland, Greg T.;
- Kipnis, Jonathan
Publication type:
Article
Phospholipase D3 drives microglial response to amyloid pathology in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076884
By:
- Rosene, Matthew J;
- Danhash, Emma;
- You, Shih‐Feng;
- Iyer, Abhirami Kannan;
- Hsu, Simon;
- de Sa Lopes, Mariana Acquarone;
- Brase, Logan;
- Verbeck, Anthony;
- Martinez, Rita;
- Wallace, Clare E;
- Li, Zeran;
- Yan, Ping;
- Drager, Nina;
- Sattler, Sydney M;
- Mahan, Thomas E;
- Macauley, Shannon L;
- Holtzman, David M.;
- Benitez, Bruno A.;
- Kampmann, Martin;
- Cruchaga, Carlos
Publication type:
Article
Characterizing Disrupted Cellular Crosstalk Signaling Networks in Alzheimer's Disease Using Single‐Nuclei Transcriptomics.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.062304
By:
- Albanus, Ricardo D'Oliveira;
- Brase, Logan;
- You, Shih‐Feng;
- Soriano‐Tarraga, Carolina;
- Benitez, Bruno A.;
- Cruchaga, Carlos;
- Karch, Celeste M.;
- Harari, Oscar
Publication type:
Article
Genetic and glial heterogeneity in Alzheimer disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.061185
By:
- Brase, Logan;
- You, Shih‐Feng;
- Novotny, Brenna C;
- Soriano‐Tarraga, Carolina;
- Morris, John C.;
- Bateman, Randall J.;
- Perrin, Richard J.;
- McDade, Eric;
- Goate, Alison;
- Karch, Celeste M.;
- Benitez, Bruno A.;
- Cruchaga, Carlos;
- Harari, Oscar
Publication type:
Article
Multi‐omics approaches reveal a link between the MS4A gene loci, TREM2, and microglia function.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054553
By:
- You, Shih‐Feng;
- Brase, Logan;
- Filipello, Fabia;
- Del‐Aguila, Jorge L.;
- Mihindukulasuriya, Kathie A.;
- Benitez, Bruno A.;
- Cruchaga, Carlos;
- Harari, Oscar;
- Karch, Celeste M.
Publication type:
Article
Single nuclei RNA‐sequencing of GWAS loci variant carriers elucidates cell‐types and transcriptional profile alterations associated with Alzheimer disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054402
By:
- Brase, Logan;
- Del‐Aguila, Jorge L.;
- You, Shih‐Feng;
- Soriano‐Tarraga, Carolina;
- Farias, Fabiana H.G.;
- Benitez, Bruno A.;
- Karch, Celeste M.;
- Cruchaga, Carlos;
- Harari, Oscar
Publication type:
Article
Functional characterization of hiPSCs‐derived glial cells and neurons from patients harboring a TREM2 loss of function mutation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058712
By:
- Filipello, Fabia;
- You, Shih‐Feng;
- Martinez, Rita;
- Korvatska, Olena;
- Raskind, Wendy H;
- Mahali, Sidhartha;
- Ghezzi, Laura;
- Wandy, Beatty;
- Cella, Marina;
- Piccio, Laura;
- Karch, Celeste M.
Publication type:
Article
Multiomics approaches reveal a link between the MS4A gene loci, TREM2, and microglia function: Genetics/omics and systems biology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043592
By:
- You, Shih‐Feng;
- He, June;
- Filipello, Fabia;
- Brase, Logan;
- Del‐Aguila, Jorge L.;
- Mihindukulasuriya, Kathie A.;
- Benitez, Bruno A.;
- Cruchaga, Carlos;
- Harari, Oscar;
- Karch, Celeste M.
Publication type:
Article
Defects in lysosomal function and lipid metabolism in human microglia harboring a TREM2 loss of function mutation.
Published in:
Acta Neuropathologica, 2023, v. 145, n. 6, p. 749, doi. 10.1007/s00401-023-02568-y
By:
- Filipello, Fabia;
- You, Shih-Feng;
- Mirfakhar, Farzaneh S.;
- Mahali, Sidhartha;
- Bollman, Bryan;
- Acquarone, Mariana;
- Korvatska, Olena;
- Marsh, Jacob A.;
- Sivaraman, Anirudh;
- Martinez, Rita;
- Cantoni, Claudia;
- De Feo, Luca;
- Ghezzi, Laura;
- Minaya, Miguel A.;
- Renganathan, Arun;
- Cashikar, Anil G.;
- Satoh, Jun-Ichi;
- Beatty, Wandy;
- Iyer, Abhirami K.;
- Cella, Marina
Publication type:
Article
Shear Wave Elasticity Measurements of Three-Dimensional Cancer Cell Cultures Using Laser Speckle Contrast Imaging.
Published in:
Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-32763-x
By:
- Chao, Pei-Yu;
- Liu, Wei-Wen;
- You, Shih-Feng;
- Li, Pai-Chi
Publication type:
Article

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