Works by Yongchang Chen

Results: 68

Activation of endogenous full-length utrophin by MyoAAV-UA as a therapeutic approach for Duchenne muscular dystrophy.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-57831-5

By:

Wu, Ruo;
Li, Peng;
Xiao, Puhao;
Zhang, Shu;
Wang, Xiaopeng;
Liu, Jie;
Sun, Wenjie;
Chang, Yue;
Ai, Xiuyi;
Chen, Lijiao;
Zhuo, Yan;
Wang, Jiaojian;
Wang, Zhengbo;
Li, Shangang;
Li, Yuanyuan;
Ji, Weizhi;
Guo, Wenting;
Wu, Shiwen;
Chen, Yongchang

Publication type:

Article

Experimental Study of Antifouling Effect of Ultrasonic/Magnetic Compound Treatment in Heat Transfer.

Published in:

Heat Transfer Engineering, 2023, v. 44, n. 1, p. 24, doi. 10.1080/01457632.2022.2027099

By:

Liu, Genyuan;
Chen, Yongchang;
Hou, Tengfei;
Ma, Chongfang

Publication type:

Article

Experimental Study on Anti-Fouling Performance in a Heat Exchanger with Low Voltage Electrolysis Treatment.

Published in:

Heat Transfer Engineering, 2009, v. 30, n. 3, p. 181, doi. 10.1080/01457630802304279

By:

Quan, Zhenhua;
Chen, Yongchang;
Ma, Chongfang;
Wang, Chunming;
Li, Bing

Publication type:

Article

Type II cGMP-dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells.

Published in:

2022

By:

Wu, Min;
Wu, Yan;
Qian, Hai;
Tao, Yan;
Pang, Ji;
Wang, Ying;
Chen, Yongchang

Publication type:

Correction Notice

Type II cGMP‑dependent protein kinase inhibits the migration, invasion and proliferation of several types of human cancer cells.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 4, p. 5729, doi. 10.3892/mmr.2017.7290

By:

MIN WU;
YAN WU;
HAI QIAN;
YAN TAO;
JI PANG.;
YING WANG;
YONGCHANG CHEN

Publication type:

Article

Exosomes derived from human mesenchymal stem cells promote gastric cancer cell growth and migration via the activation of the Akt pathway.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 4, p. 3452, doi. 10.3892/mmr.2016.5625

By:

HONGBING GU;
RUNBI JI;
XU ZHANG2;
MEI WANG;
WEI ZHU;
HUI QIAN;
YONGCHANG CHEN;
PENGCHENG JIANG;
WENRONG XU

Publication type:

Article

Type II cGMP-dependent protein kinase inhibits EGF-induced JAK/STAT signaling in gastric cancer cells.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 2, p. 1849, doi. 10.3892/mmr.2016.5452

By:

MIN WU;
YAN WU;
TING LAN;
LU JIANG;
HAI QIAN;
YONGCHANG CHEN

Publication type:

Article

Type II cGMP-dependent protein kinase directly inhibits HER2 activation of gastric cancer cells.

Published in:

Molecular Medicine Reports, 2016, v. 13, n. 2, p. 1909, doi. 10.3892/mmr.2015.4688

By:

MIAOLIN ZHU;
XIAOYUAN YAO;
MIN WU;
HAI QIAN;
YAN WU;
YONGCHANG CHEN

Publication type:

Article

Type II cGMP.dependent protein kinase inhibits RhoA activation in gastric cancer cells.

Published in:

Molecular Medicine Reports, 2014, v. 9, n. 4, p. 1444, doi. 10.3892/mmr.2014.1960

By:

YING WANG;
YONGCHANG CHEN;
YUEYING LI;
TING LAN;
HAI QIAN

Publication type:

Article

Type II cGMP-dependent protein kinase inhibits ligand.induced activation of EGFR in gastric cancer cells.

Published in:

Molecular Medicine Reports, 2014, v. 9, n. 4, p. 1405, doi. 10.3892/mmr.2014.1942

By:

LU JIANG;
YONGCHANG CHEN;
YUEYING LI;
TING LAN;
MIN WU;
YING WANG;
HAI QIAN

Publication type:

Article

Refining GPS/GLONASS Satellite Clock Offset Estimation in the Presence of Pseudo-Range Inter-Channel Biases.

Published in:

Remote Sensing, 2020, v. 12, n. 11, p. 1821, doi. 10.3390/rs12111821

By:

Ai, Qingsong;
Yuan, Yunbin;
Zhang, Baocheng;
Xu, Tianhe;
Chen, Yongchang

Publication type:

Article

Progress in Modeling Neural Tube Development and Defects by Organoid Reconstruction.

Published in:

Neuroscience Bulletin, 2022, v. 38, n. 11, p. 1409, doi. 10.1007/s12264-022-00896-9

By:

Li, Peng;
Chen, Yongchang

Publication type:

Article

Interaction of p53 and ASPPs regulates rhesus monkey embryonic stem cells conversion to neural fate concomitant with apoptosis.

Published in:

Cell Cycle, 2018, v. 17, n. 9, p. 1146, doi. 10.1080/15384101.2018.1464848

By:

Wang, Shuang;
Yang, Lichuan;
Bai, Raoxian;
Ren, Shuaiwei;
Niu, Yuyu;
Ma, Yuanye;
Ji, Weizhi;
Chen, Yongchang

Publication type:

Article

On the zero set of the holomorphic sectional curvature.

Published in:

Mathematische Nachrichten, 2024, v. 297, n. 6, p. 2333, doi. 10.1002/mana.202300424

By:

Chen, Yongchang;
Heier, Gordon

Publication type:

Article

Secretory type II cGMP‐dependent protein kinase blocks activation of PDGFRβ via Ser254 in gastric cancer cells.

Published in:

Cell Biology International, 2022, v. 46, n. 5, p. 747, doi. 10.1002/cbin.11766

By:

Pang, Ji;
Li, Guorui;
Qian, Hai;
Wu, Yan;
Chen, Yongchang

Publication type:

Article

PKG II inhibits PDGF‐BB triggered biological activities by phosphorylating PDGFRβ in gastric cancer cells.

Published in:

Cell Biology International, 2018, v. 42, n. 10, p. 1358, doi. 10.1002/cbin.11020

By:

Wang, Ying;
Lan, Ting;
Wu, Min;
Pang, Ji;
Qian, Hai;
Tao, Yan;
Jiang, Lu;
Wu, Yan;
Chen, Yongchang;
Appiah‐Kubi, Kwaku

Publication type:

Article

PKG II effectively reversed EGF‐induced protein expression alterations in human gastric cancer cell lines.

Published in:

Cell Biology International, 2018, v. 42, n. 4, p. 435, doi. 10.1002/cbin.10912

By:

Qian, Hai;
Tao, Yan;
Jiang, Lu;
Wang, Ying;
Lan, Ting;
Wu, Min;
Pang, Ji;
Appiah‐Kubi, Kwaku;
Chen, Yongchang;
Wu, Yan

Publication type:

Article

Human mesenchymal stem cells isolated from the umbilical cord

Published in:

Cell Biology International, 2008, v. 32, n. 1, p. 8, doi. 10.1016/j.cellbi.2007.08.002

By:

Qiao, Chun;
Xu, Wenrong;
Zhu, Wei;
Hu, Jiabo;
Qian, Hui;
Yin, Qing;
Jiang, Runqiu;
Yan, Yongmin;
Mao, Fei;
Yang, Huan;
Wang, Xingzhong;
Chen, Yongchang

Publication type:

Article

Positivity of Δ-genera for connected polarized demi-normal schemes.

Published in:

Communications in Algebra, 2024, v. 52, n. 6, p. 2305, doi. 10.1080/00927872.2023.2300435

By:

Chen, Jingshan;
Chen, Yongchang

Publication type:

Article

Amnion signals are essential for mesoderm formation in primates.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25186-2

By:

Yang, Ran;
Goedel, Alexander;
Kang, Yu;
Si, Chenyang;
Chu, Chu;
Zheng, Yi;
Chen, Zhenzhen;
Gruber, Peter J.;
Xiao, Yao;
Zhou, Chikai;
Witman, Nevin;
Eroglu, Elif;
Leung, Chuen-Yan;
Chen, Yongchang;
Fu, Jianping;
Ji, Weizhi;
Lanner, Fredrik;
Niu, Yuyu;
Chien, Kenneth R.

Publication type:

Article

Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection.

Published in:

Journal of Molecular Cell Biology, 2014, v. 6, n. 2, p. 172, doi. 10.1093/jmcb/mjt052

By:

Zhang, Yunfang;
Zhang, Ying;
Shi, Junchao;
Zhang, He;
Cao, Zhonghong;
Gao, Xuan;
Ren, Wanhua;
Ning, Yunna;
Ning, Lina;
Cao, Yujing;
Chen, Yongchang;
Ji, Weizhi;
Chen, Zi-jiang;
Chen, Qi;
Duan, Enkui

Publication type:

Article

Active PKG II inhibited the growth and migration of ovarian cancer cells through blocking Raf/MEK and PI3K/Akt signaling pathways.

Published in:

Bioscience Reports, 2019, v. 39, n. 8, p. 1, doi. 10.1042/BSR20190405

By:

Yan Wu;
Qin Cai;
Wei Li;
Zhensheng Cai;
Ying Liu;
Hongfan Li;
Ji Pang;
Yongchang Chen

Publication type:

Article

IFI16 promotes the progression of clear cell renal cell carcinoma through the IL6/PI3K/AKT axis.

Published in:

Journal of Translational Medicine, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12967-024-05354-w

By:

Lu, Ke;
Zhao, Yan;
Li, Yu;
Fu, Zhenyu;
Chen, Yongchang;
Kong, Ying;
Li, Gang

Publication type:

Article

Homologous recombination-mediated targeted integration in monkey embryos using TALE nucleases.

Published in:

BMC Biotechnology, 2019, v. 19, n. 1, p. N.PAG, doi. 10.1186/s12896-018-0494-2

By:

Chu, Chu;
Yang, Zhaohui;
Yang, Jiayin;
Yan, Li;
Si, Chenyang;
Kang, Yu;
Chen, Zhenzhen;
Chen, Yongchang;
Ji, Weizhi;
Niu, Yuyu

Publication type:

Article

The Available Time Window for Embryo Transfer in the Rhesus Monkey ( Macaca mulatta).

Published in:

American Journal of Primatology, 2012, v. 74, n. 2, p. 165, doi. 10.1002/ajp.21017

By:

CHEN, YONGCHANG;
NIU, YUYU;
YANG, SHIHUA;
HE, XIECHAO;
JI, SHAOHUI;
SI, WEI;
TANG, XIANGHUI;
XIE, YUNHUA;
WANG, HONG;
LU, YONGQING;
ZHOU, QI;
JI, WEIZHI

Publication type:

Article

Neural Stem Cells Transplanted into Rhesus Monkey Cortical Traumatic Brain Injury Can Survive and Differentiate into Neurons.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 3, p. 1642, doi. 10.3390/ijms25031642

By:

Liu, Shuyi;
Shi, Liping;
Huang, Tianzhuang;
Luo, Yuyi;
Chen, Yongchang;
Li, Shangang;
Wang, Zhengbo

Publication type:

Article

Acacetin Attenuates Cigarette Smoke Extract-Induced Human Bronchial Epithelial Cell Injury by Activating NRF2/SLC7A11/GPX4 Signaling to Inhibit Ferroptosis.

Published in:

Cell Biochemistry & Biophysics, 2025, v. 83, n. 2, p. 2499, doi. 10.1007/s12013-024-01659-1

By:

Chen, Yongchang;
Wu, Yan;
Dong, Juan;
Zhang, Chuanming;
Tang, Jia

Publication type:

Article

The constitutively active PKG II mutant effectively inhibits gastric cancer development via a blockade of EGF/EGFR-associated signalling cascades.

Published in:

Therapeutic Advances in Medical Oncology, 2018, v. 10, n. 1, p. 1, doi. 10.1177/1758834017751635

By:

Wu, Yan;
Yuan, Miaomiao;
Su, Wenbin;
Zhu, Miaolin;
Yao, Xiaoyuan;
Wang, Ying;
Qian, Hai;
Jiang, Lu;
Tao, Yan;
Wu, Min;
Pang, Ji;
Chen, Yongchang

Publication type:

Article

Folic acid deficiency inhibits neural rosette formation and neuronal differentiation from rhesus monkey embryonic stem cells.

Published in:

Journal of Neuroscience Research, 2012, v. 90, n. 7, p. 1382, doi. 10.1002/jnr.23030

By:

Chen, Yongchang;
Wang, Zhengbo;
Xie, Yunhua;
Guo, Xiangyu;
Tang, Xianghui;
Wang, Shufen;
Yang, Shihua;
Chen, Kai;
Niu, Yuyu;
Ji, Weizhi

Publication type:

Article

The Cross Talk Between Protein Kinase A– and RhoA-Mediated Signaling in Cancer Cells.

Published in:

Experimental Biology & Medicine, 2005, v. 230, n. 10, p. 731, doi. 10.1177/153537020523001006

By:

Chen, Yongchang;
Wang, Ying;
Yu, Hao;
Wang, Fengwei;
Xu, Wenrong

Publication type:

Article

Mesenchymal Stern Cells from Adult Human Bone Marrow Differentiate into a Cardiomyocyte Phenotype In Vitro.

Published in:

Experimental Biology & Medicine, 2004, v. 229, n. 7, p. 623, doi. 10.1177/153537020422900706

By:

Xu, Wenrong;
Zhang, Xiran;
Qian, Hui;
Zhu, Wei;
Sun, Xiaochun;
Hu, Jiabo;
Zhou, Hong;
Chen, Yongchang

Publication type:

Article

Cyclic Guanosine Monophosphate (cGMP)-Dependent Protein Kinase II Blocks Epidermal Growth Factor (EGF)/Epidermal Growth Factor Receptor (EGFR)-Induced Biological Effects on Osteosarcoma Cells.

Published in:

Medical Science Monitor, 2018, v. 24, p. 1997, doi. 10.12659/MSM.905892

By:

Dapeng Li;
Ye Hua;
Lu Jiang;
Yonghui Huang;
Jiawei Yue;
Yan Wu;
Yongchang Chen

Publication type:

Article

Protein Kinases Type II (PKG II) Combined with L-Arginine Significantly Ameliorated Xenograft Tumor Development: Is L-Arginine a Potential Alternative in PKG II Activation?

Published in:

Medical Science Monitor, 2018, v. 24, p. 736, doi. 10.12659/MSM.906213

By:

Yan Wu;
Ying Liu;
Zhensheng Cai;
Huijuan Qin;
Hongfan Li;
Wenbin Su;
Ying Wang;
Hai Qian;
Lu Jiang;
Min Wu;
Ji Pang;
Yongchang Chen

Publication type:

Article

Extracapsular extension of transitional zone prostate cancer miss-detected by multiparametric magnetic resonance imaging.

Published in:

Journal of Cancer Research & Clinical Oncology, 2023, v. 149, n. 10, p. 6943, doi. 10.1007/s00432-023-04573-w

By:

Chen, Xin;
Li, Wei;
Yang, Jiajian;
Huang, Chen;
Zhou, Chenchao;
Chen, Yongchang;
Lin, Yuxin;
Hou, Jianquan;
Huang, Yuhua;
Wei, Xuedong

Publication type:

Article

Dynamic manifold Boltzmann optimization based on self‐supervised learning for human motion estimation.

Published in:

IET Image Processing (Wiley-Blackwell), 2022, v. 16, n. 4, p. 1162, doi. 10.1049/ipr2.12400

By:

Li, Wanyi;
Zeng, Yuqi;
Wu, Yilin;
Zhang, Qian;
Chen, Guoming;
Chen, Yongchang

Publication type:

Article

The platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) are major players in oncogenesis, drug resistance, and attractive oncologic targets in cancer.

Published in:

Growth Factors, 2016, v. 34, n. 1/2, p. 64, doi. 10.1080/08977194.2016.1180293

By:

Wang, Ying;
Appiah-Kubi, Kwaku;
Wu, Min;
Yao, Xiaoyuan;
Qian, Hai;
Wu, Yan;
Chen, Yongchang

Publication type:

Article

Seismic Performance of Wall-Type Concrete-Filled Steel Tubular Column to H-Beam Connections with Internal Diaphragms.

Published in:

Buildings (2075-5309), 2024, v. 14, n. 6, p. 1741, doi. 10.3390/buildings14061741

By:

Liu, Hanchao;
Lei, Honggang;
Huang, Yuqi;
Chen, Yongchang;
Xu, Feng

Publication type:

Article

TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1α degradation.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2022, v. 41, n. 1, p. 1, doi. 10.1186/s13046-022-02252-1

By:

Chen, Yongchang;
Liu, Lu;
Xia, Longzheng;
Wu, Nayiyuan;
Wang, Ying;
Li, He;
Chen, Xue;
Zhang, Xiaoye;
Liu, Zhaoyi;
Zhu, Miaochen;
Liao, Qianjin;
Wang, Jing

Publication type:

Article

Transgenic rhesus monkeys carrying the human MCPH1 gene copies show human-like neoteny of brain development.

Published in:

National Science Review, 2019, v. 6, n. 3, p. 480, doi. 10.1093/nsr/nwz043

By:

Shi, Lei;
Luo, Xin;
Jiang, Jin;
Chen, Yongchang;
Liu, Cirong;
Hu, Ting;
Li, Min;
Lin, Qiang;
Li, Yanjiao;
Huang, Jun;
Wang, Hong;
Niu, Yuyu;
Shi, Yundi;
Styner, Martin;
Wang, Jianhong;
Lu, Yi;
Sun, Xuejin;
Yu, Hualin;
Ji, Weizhi;
Su, Bing

Publication type:

Article

Bilobol inhibits the lipopolysaccharide-induced expression and distribution of RhoA in HepG2 human hepatocellular carcinoma cells.

Published in:

Oncology Letters, 2015, v. 10, n. 2, p. 962, doi. 10.3892/ol.2015.3276

By:

JIN XU;
YUEYING LI;
XIAOMING YANG;
YALI LIU;
YONGCHANG CHEN;
MIN CHEN

Publication type:

Article

Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells.

Published in:

Oncology Letters, 2015, v. 10, n. 1, p. 502, doi. 10.3892/ol.2015.3173

By:

YING WANG;
YONGCHANG CHEN;
MIN WU;
TING LAN;
YAN WU;
YUEYING LI;
HAI QIAN

Publication type:

Article

Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase.

Published in:

Oncology Letters, 2015, v. 10, n. 1, p. 479, doi. 10.3892/ol.2015.3229

By:

XIAOYUAN YAO;
YAN WU;
MIAOLIN ZHU;
HAI QIAN;
YONGCHANG CHEN

Publication type:

Article

Type II cyclic guanosine monophosphate-dependent protein kinase inhibits epidermal growth factor receptor activation in different cancer cell lines.

Published in:

Oncology Letters, 2015, v. 9, n. 6, p. 2781, doi. 10.3892/ol.2015.3067

By:

LU JIANG;
MIN WU;
YAN WU;
TING LAN;
YING WANG;
HAI QIAN;
YONGCHANG CHEN

Publication type:

Article

Type II cGMP-dependent protein kinase inhibits epidermal growth factor-induced phosphatidylinositol-3-kinase/Akt signal transduction in gastric cancer cells.

Published in:

Oncology Letters, 2013, v. 6, n. 6, p. 1723, doi. 10.3892/ol.2013.1630

By:

MIN WU;
YONGCHANG CHEN;
LU JIANG;
YUEYING LI;
TING LAN;
YING WANG;
HAI QIAN

Publication type:

Article

Cross-linked hyaluronan gel inhibits the growth and metastasis of ovarian carcinoma.

Published in:

Journal of Ovarian Research, 2018, v. 11, p. 1, doi. 10.1186/s13048-018-0394-z

By:

Pang, Ji;
Jiang, Pengcheng;
Wang, Ying;
Jiang, Lu;
Qian, Hai;
Tao, Yan;
Shi, Ruxia;
Gao, Jizong;
Chen, Yongchang;
Wu, Yan

Publication type:

Article

Multiple coagulation factor deficiency protein 2 contains the ability to support stem cell self-renewal.

Published in:

FASEB Journal, 2013, v. 27, n. 8, p. 3298, doi. 10.1096/fj.13-228825

By:

Huan Liu;
Bo Zhao;
Yongchang Chen;
Dewen You;
Rui Liu;
Mingqiang Rong;
Weizhi Ji;
Ping Zheng;
Ren Lai

Publication type:

Article

Advances in the pathogenesis of Rett syndrome using cell models.

Published in:

Animal Models & Experimental Medicine, 2022, v. 5, n. 6, p. 532, doi. 10.1002/ame2.12236

By:

Lu, Sijia;
Chen, Yongchang;
Wang, Zhengbo

Publication type:

Article

Disentangling the Switching Behavior in Functional Connectivity Dynamics in Autism Spectrum Disorder: Insights from Developmental Cohort Analysis and Molecular‐Cellular Associations.

Published in:

Advanced Science, 2025, v. 12, n. 20, p. 1, doi. 10.1002/advs.202403801

By:

Li, Wei;
Qiu, Xia;
Chen, Jin;
Chen, Kexuan;
Chen, Meiling;
Wang, Yinyan;
Sun, Wenjie;
Su, Jing;
Chen, Yongchang;
Liu, Xiaobao;
Chu, Congying;
Wang, Jiaojian

Publication type:

Article

Analysis of the efficacy of a single subumbilical stoma for bilateral cutaneous ureterostomy after radical cystectomy.

Published in:

European Journal of Medical Research, 2023, v. 28, n. 1, p. 1, doi. 10.1186/s40001-023-01250-z

By:

Fu, Zhenyu;
Tian, Zhen;
Chen, Yongchang;
Jia, Zongming;
Wang, Chengyu;
Zhang, Xuefeng;
Zhang, Weijie;
Li, Gang;
Wei, Xuedong;
Huang, Yuhua

Publication type:

Article

PKG II Inhibits EGF/EGFR-Induced Migration of Gastric Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061674

By:

Jiang, Lu;
Lan, Ting;
Chen, Yongchang;
Sang, Jianrong;
Li, Yueying;
Wu, Min;
Tao, Yan;
Wang, Ying;
Qian, Hai;
Gu, Luo

Publication type:

Article