Works matching AU Yong-Jie Zhang

Results: 99
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    Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress.

    Published in:
    Acta Neuropathologica, 2014, v. 128, n. 4, p. 505, doi. 10.1007/s00401-014-1336-5
    By:
    • Zhang, Yong-Jie;
    • Jansen-West, Karen;
    • Xu, Ya-Fei;
    • Gendron, Tania;
    • Bieniek, Kevin;
    • Lin, Wen-Lang;
    • Sasaguri, Hiroki;
    • Caulfield, Thomas;
    • Hubbard, Jaime;
    • Daughrity, Lillian;
    • Chew, Jeannie;
    • Belzil, Veronique;
    • Prudencio, Mercedes;
    • Stankowski, Jeannette;
    • Castanedes-Casey, Monica;
    • Whitelaw, Ena;
    • Ash, Peter;
    • DeTure, Michael;
    • Rademakers, Rosa;
    • Boylan, Kevin
    Publication type:
    Article
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    Mechanisms of toxicity in C9FTLD/ALS.

    Published in:
    Acta Neuropathologica, 2014, v. 127, n. 3, p. 359, doi. 10.1007/s00401-013-1237-z
    By:
    • Gendron, Tania;
    • Belzil, Veronique;
    • Zhang, Yong-Jie;
    • Petrucelli, Leonard
    Publication type:
    Article
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    Antisense transcripts of the expanded <i>C9ORF72</i> hexanucleotide repeat form nuclear RNA foci and undergo repeat-associated non-ATG translation in c9FTD/ALS.

    Published in:
    Acta Neuropathologica, 2013, v. 126, n. 6, p. 829, doi. 10.1007/s00401-013-1192-8
    By:
    • Gendron, Tania F.;
    • Bieniek, Kevin F.;
    • Zhang, Yong-Jie;
    • Jansen-West, Karen;
    • Ash, Peter E. A.;
    • Caulfield, Thomas;
    • Daughrity, Lillian;
    • Dunmore, Judith H.;
    • Castanedes-Casey, Monica;
    • Chew, Jeannie;
    • Cosio, Danielle M.;
    • van Blitterswijk, Marka;
    • Lee, Wing C.;
    • Rademakers, Rosa;
    • Boylan, Kevin B.;
    • Dickson, Dennis W.;
    • Petrucelli, Leonard
    Publication type:
    Article
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    Repetitive element transcripts are elevated in the brain of C9orf72 ALS/FTLD patients.

    Published in:
    Human Molecular Genetics, 2017, v. 26, n. 17, p. 3421, doi. 10.1093/hmg/ddx233
    By:
    • Prudencio, Mercedes;
    • Gonzales, Patrick K.;
    • Cook, Casey N.;
    • Gendron, Tania F.;
    • Daughrity, Lillian M.;
    • Song, Yuping;
    • Ebbert, Mark T. W.;
    • van Blitterswijk, Marka;
    • Zhang, Yong-Jie;
    • Jansen-West, Karen;
    • Baker, Matthew C.;
    • DeTure, Michael;
    • Rademakers, Rosa;
    • Boylan, Kevin B.;
    • Dickson, Dennis W.;
    • Petrucelli, Leonard;
    • Link, Christopher D.
    Publication type:
    Article
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    Targeted manipulation of the sortilin–progranulin axis rescues progranulin haploinsufficiency.

    Published in:
    Human Molecular Genetics, 2014, v. 23, n. 6, p. 1467, doi. 10.1093/hmg/ddt534
    By:
    • Lee, Wing C.;
    • Almeida, Sandra;
    • Prudencio, Mercedes;
    • Caulfield, Thomas R.;
    • Zhang, Yong-Jie;
    • Tay, William M.;
    • Bauer, Peter O.;
    • Chew, Jeannie;
    • Sasaguri, Hiroki;
    • Jansen-West, Karen R.;
    • Gendron, Tania F.;
    • Stetler, Caroline T.;
    • Finch, NiCole;
    • Mackenzie, Ian R.;
    • Rademakers, Rosa;
    • Gao, Fen-Biao;
    • Petrucelli, Leonard
    Publication type:
    Article
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    Mis-spliced transcripts generate de novo proteins in TDP-43–related ALS/FTD.

    Published in:
    Science Translational Medicine, 2024, v. 16, n. 734, p. 1, doi. 10.1126/scitranslmed.adg7162
    By:
    • Seddighi, Sahba;
    • Qi, Yue A.;
    • Brown, Anna-Leigh;
    • Wilkins, Oscar G.;
    • Bereda, Colleen;
    • Belair, Cedric;
    • Zhang, Yong-Jie;
    • Prudencio, Mercedes;
    • Keuss, Matthew J.;
    • Khandeshi, Aditya;
    • Pickles, Sarah;
    • Kargbo-Hill, Sarah E.;
    • Hawrot, James;
    • Ramos, Daniel M.;
    • Yuan, Hebao;
    • Roberts, Jessica;
    • Sacramento, Erika Kelmer;
    • Shah, Syed I.;
    • Nalls, Mike A.;
    • Colón-Mercado, Jennifer M.
    Publication type:
    Article
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    Poly(ADP-ribose) promotes toxicity of C9ORF72 arginine-rich dipeptide repeat proteins.

    Published in:
    Science Translational Medicine, 2022, v. 14, n. 662, p. 1, doi. 10.1126/scitranslmed.abq3215
    By:
    • Gao, Junli;
    • Mewborne, Quinlan T.;
    • Girdhar, Amandeep;
    • Sheth, Udit;
    • Coyne, Alyssa N.;
    • Punathil, Ritika;
    • Kang, Bong Gu;
    • Dasovich, Morgan;
    • Veire, Austin;
    • DeJesus Hernandez, Mariely;
    • Liu, Shuaichen;
    • Shi, Zheng;
    • Dafinca, Ruxandra;
    • Fouquerel, Elise;
    • Talbot, Kevin;
    • Kam, Tae-In;
    • Zhang, Yong-Jie;
    • Dickson, Dennis;
    • Petrucelli, Leonard;
    • van Blitterswijk, Marka
    Publication type:
    Article
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