Works by Yoder, Bradley K.

Results: 35

T cell‐expressed Ift88 is required for proper thymocyte differentiation in mice.

Published in:

Physiological Reports, 2024, v. 12, n. 22, p. 1, doi. 10.14814/phy2.70120

By:

Miller, Sarah J.;
Gonzalez, Nancy M.;
Smith, Morgan E.;
Croyle, Mandy J.;
Yoder, Bradley K.;
Zimmerman, Kurt A.

Publication type:

Article

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

Published in:

Nature Genetics, 2008, v. 40, n. 4, p. 403, doi. 10.1038/ng.105

By:

Tran, Pamela V.;
Haycraft, Courtney J.;
Besschetnova, Tatiana Y.;
Turbe-Doan, Annick;
Stottmann, Rolf W.;
Herron, Bruce J.;
Chesebro, Allyson L.;
Haiyan Qiu;
Scherz, Paul J.;
Shah, Jagesh V.;
Yoder, Bradley K.;
Beier, David R.

Publication type:

Article

Ciliary proteins link basal body polarization to planar cell polarity regulation.

Published in:

Nature Genetics, 2008, v. 40, n. 1, p. 69, doi. 10.1038/ng.2007.54

By:

Jones, Chonnettia;
Roper, Venus C.;
Foucher, Isabelle;
Dong Qian;
Banizs, Boglarka;
Petit, Christine;
Yoder, Bradley K.;
Ping Chen

Publication type:

Article

Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00664-z

By:

Wilk, Elizabeth J.;
Howton, Timothy C.;
Fisher, Jennifer L.;
Oza, Vishal H.;
Brownlee, Ryan T.;
McPherson, Kasi C.;
Cleary, Hannah L.;
Yoder, Bradley K.;
George, James F.;
Mrug, Michal;
Lasseigne, Brittany N.

Publication type:

Article

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis.

Published in:

Journal of Cell Biology, 2011, v. 192, n. 6, p. 1023, doi. 10.1083/jcb.201012116

By:

Williams, Corey L.;
Chunmei Li;
Kida, Katarzyna;
Inglis, Peter N.;
Mohan, Swetha;
Semenec, Lucie;
Bialas, Nathan J.;
Stupay, Rachel M.;
Nansheng Chen;
Blacque, Oliver E.;
Yoder, Bradley K.;
Leroux, Michel R.

Publication type:

Article

Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0135678

By:

Mrug, Michal;
Zhou, Juling;
Yang, Chaozhe;
Aronow, Bruce J.;
Cui, Xiangqin;
Schoeb, Trenton R.;
Siegal, Gene P.;
Yoder, Bradley K;
Guay-Woodford, Lisa M.

Publication type:

Article

High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0114632

By:

Thomas, Holly R.;
Percival, Stefanie M.;
Yoder, Bradley K.;
Parant, John M.

Publication type:

Article

Hippocampal and Cortical Primary Cilia Are Required for Aversive Memory in Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106576

By:

Berbari, Nicolas F.;
Malarkey, Erik B.;
Yazdi, S. M. Zaki R.;
McNair, Andrew D.;
Kippe, Jordyn M.;
Croyle, Mandy J.;
Kraft, Timothy W.;
Yoder, Bradley K.

Publication type:

Article

Quantitative Peptidomics of Purkinje Cell Degeneration Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060981

By:

Berezniuk, Iryna;
Sironi, Juan J.;
Wardman, Jonathan;
Pasek, Raymond C.;
Berbari, Nicolas F.;
Yoder, Bradley K.;
Fricker, Lloyd D.

Publication type:

Article

Mks6 mutations reveal tissue- and cell type-specific roles for the cilia transition zone.

Published in:

FASEB Journal, 2019, v. 33, n. 1, p. 1440, doi. 10.1096/fj.201801149R

By:

Lewis, Wesley R.;
Bales, Katie L.;
Revell, Dustin Z.;
Croyle, Mandy J.;
Engle, Staci E.;
Cheng Jack Song;
Malarkey, Erik B.;
Uytingco, Cedric R.;
Dan Shan;
Antonellis, Patrick J.;
Nagy, Tim R.;
Kesterson, Robert A.;
Mrug, Michal M.;
Martens, Jeffrey R.;
Berbari, Nicolas F.;
Gross, Alecia K.;
Yoder, Bradley K.

Publication type:

Article

NHE Dysregulation in Cilium Deficient Mouse Renal Principal Cells from orpk Mice.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A504, doi. 10.1096/fasebj.21.5.a504

By:

Olteanu, Dragos S.;
Yoder, Bradley K.;
Bevensee, Mark O.;
Schwiebert, Erik M.

Publication type:

Article

Autocrine Purinergic Signaling Is Required for Monocilium-driven Signaling.

Published in:

FASEB Journal, 2007, v. 21, n. 5, p. A503

By:

Hovater, Michael B.;
Olteanu, Dragos S.;
Yoder, Bradley K.;
Schwiebert, Erik M.

Publication type:

Article

Characterization of Growth Factor Responsiveness and Alterations in Growth Factor Homeostasis Involved in the Tumorigenic Conversion of Mouse Oval Cells.

Published in:

Growth Factors, 1998, v. 15, n. 2, p. 81, doi. 10.3109/08977199809117185

By:

Isfort, Robert J.;
Cody, David B.;
Richards, William G.;
Yoder, Bradley K.;
Wilkinson, J. Erby;
Woychik, Richard P.

Publication type:

Article

A mouse model of BBS identifies developmental and homeostatic effects of BBS5 mutation and identifies novel pituitary abnormalities.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 3/4, p. 234, doi. 10.1093/hmg/ddab039

By:

Bentley-Ford, Melissa R;
Engle, Staci E;
Clearman, Kelsey R;
Haycraft, Courtney J;
Andersen, Reagan S;
Croyle, Mandy J;
Rains, Addison B;
Berbari, Nicolas F;
Yoder, Bradley K

Publication type:

Article

Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease.

Published in:

PLoS Genetics, 2016, v. 12, n. 7, p. 1, doi. 10.1371/journal.pgen.1006220

By:

Lewis, Wesley R.;
Malarkey, Erik B.;
Tritschler, Douglas;
Bower, Raqual;
Pasek, Raymond C.;
Porath, Jonathan D.;
Birket, Susan E.;
Saunier, Sophie;
Antignac, Corinne;
Knowles, Michael R.;
Leigh, Margaret W.;
Zariwala, Maimoona A.;
Challa, Anil K.;
Kesterson, Robert A.;
Rowe, Steven M.;
Drummond, Iain A.;
Parant, John M.;
Hildebrandt, Friedhelm;
Porter, Mary E.;
Yoder, Bradley K.

Publication type:

Article

A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4.

Published in:

PLoS Genetics, 2016, v. 12, n. 2, p. 1, doi. 10.1371/journal.pgen.1005841

By:

Masyukova, Svetlana V.;
Landis, Dawn E.;
Henke, Scott J.;
Williams, Corey L.;
Pieczynski, Jay N.;
Roszczynialski, Kelly N.;
Covington, Jannese E.;
Malarkey, Erik B.;
Yoder, Bradley K.

Publication type:

Article

Directional Cell Migration and Chemotaxis in Wound Healing Response to PDGF-AA are Coordinated by the Primary Cilium in Fibroblasts.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2010, v. 25, n. 2/3, p. 279, doi. 10.1159/000276562

By:

Schneider, Linda;
Cammer, Michael;
Lehman, Jonathan;
Nielsen, Sonja K.;
Guerra, Charles F.;
Veland, Iben R.;
Stock, Christian;
Hoffmann, Else K.;
Yoder, Bradley K.;
Schwab, Albrecht;
Satir, Peter;
Christensen, Søren T.

Publication type:

Article

Evolutionarily conserved genetic interactions between nphp-4 and bbs-5 mutations exacerbate ciliopathy phenotypes.

Published in:

Genetics, 2022, v. 220, n. 1, p. 1, doi. 10.1093/genetics/iyab209

By:

Bentley-Ford, Melissa R.;
LaBonty, Melissa;
Thomas, Holly R.;
Haycraft, Courtney J.;
Scott, Mikyla;
LaFayette, Cameron;
Croyle, Mandy J.;
Andersen, Reagan S.;
Parant, John M.;
Yoder, Bradley K.

Publication type:

Article

The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene.

Published in:

Oncogene, 1997, v. 15, n. 15, p. 1797, doi. 10.1038/sj.onc.1201535

By:

Isfort, Robert J;
Cody, David B;
Doersen, Claus-Jens;
Richards, William G;
Yoder, Bradley K;
Wilkinson, J Erby;
Kier, Larry D;
Jirtle, Randy L;
Isenberg, Jason S;
Klounig, James E;
Woychik, Richard P

Publication type:

Article

Role for intraflagellar transport in building a functional transition zone.

Published in:

EMBO Reports, 2018, v. 19, n. 12, p. N.PAG, doi. 10.15252/embr.201845862

By:

Jensen, Victor L;
Lambacher, Nils J;
Li, Chunmei;
Mohan, Swetha;
Williams, Corey L;
Inglis, Peter N;
Yoder, Bradley K;
Blacque, Oliver E;
Leroux, Michel R

Publication type:

Article

Urinary T cells correlate with rate of renal function loss in autosomal dominant polycystic kidney disease.

Published in:

Physiological Reports, 2019, v. 7, n. 1, p. N.PAG, doi. 10.14814/phy2.13951

By:

Zimmerman, Kurt A.;
Gonzalez, Nancy M.;
Chumley, Phillip;
Chacana, Teresa;
Harrington, Laurie E.;
Yoder, Bradley K.;
Mrug, Michal

Publication type:

Article

Human transcription factors responsive to initial reprogramming predominantly undergo legitimate reprogramming during fibroblast conversion to iPSCs.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-76705-y

By:

Cevallos, Ricardo R.;
Edwards, Yvonne J. K.;
Parant, John M.;
Yoder, Bradley K.;
Hu, Kejin

Publication type:

Article

Assessing the pathogenic potential of human Nephronophthisis disease-associated NPHP-4 missense mutations in C. elegans.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 15, p. 2942, doi. 10.1093/hmg/ddr198

By:

Masyukova, Svetlana V.;
Winkelbauer, Marlene E.;
Williams, Corey L.;
Pieczynski, Jay N.;
Yoder, Bradley K.

Publication type:

Article

Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type Tg737 cDNA.

Published in:

Kidney International, 1996, v. 50, n. 4, p. 1240, doi. 10.1038/ki.1996.433

By:

Yoder, Bradley K.;
Richards, William G.;
Sommardahl, Carla;
Sweeney, William E.;
Michaud, Edward J.;
Wilkinson, J. Erby;
Avner, Ellis D.;
Woychik, Richard P.

Publication type:

Article

Increased flux through the mevalonate pathway mediates fibrotic repair without injury.

Published in:

2019

By:

Larson-Casey, Jennifer L.;
Vaid, Mudit;
Linlin Gu;
Chao He;
Guo-Qiang Cai;
Qiang Ding;
Davis, Dana;
Berryhill, Taylor F.;
Wilson, Landon S.;
Barnes, Stephen;
Neighbors, Jeffrey D.;
Hohl, Raymond J.;
Zimmerman, Kurt A.;
Yoder, Bradley K.;
Longhini, Ana Leda F.;
Hanumanthu, Vidya Sagar;
Surolia, Ranu;
Antony, Veena B.;
Carter, A. Brent;
Gu, Linlin

Publication type:

journal article

Loss of the Tg737 protein results in skeletal patterning defects.

Published in:

Developmental Dynamics, 2003, v. 227, n. 1, p. 78

By:

Qihong Zhang;
Noel S. Murcia;
Laura R. Chittenden;
William G. Richards;
Edward J. Michaud;
Richard P. Woychik;
Bradley K. Yoder

Publication type:

Article

An Essential Role for Dermal Primary Cilia in Hair Follicle Morphogenesis.

Published in:

Journal of Investigative Dermatology, 2009, v. 129, n. 2, p. 438, doi. 10.1038/jid.2008.279

By:

Lehman, Jonathan M.;
Laag, Essam;
Michaud, Edward J.;
Yoder, Bradley K.

Publication type:

Article

Microtubule modifications and stability are altered by cilia perturbation and in cystic kidney disease.

Published in:

Cytoskeleton, 2013, v. 70, n. 1, p. 24, doi. 10.1002/cm.21088

By:

Berbari, Nicolas F.;
Sharma, Neeraj;
Malarkey, Erik B.;
Pieczynski, Jay N.;
Boddu, Ravindra;
Gaertig, Jacek;
Guay‐Woodford, Lisa;
Yoder, Bradley K.

Publication type:

Article

A transgenic Alx4‐CreER mouse to analyze anterior limb and nephric duct development.

Published in:

Developmental Dynamics, 2022, v. 251, n. 9, p. 1524, doi. 10.1002/dvdy.328

By:

Rockwell, Devan M.;
O'Connor, Amber K.;
Bentley‐Ford, Melissa R.;
Haycraft, Courtney J.;
Croyle, Mandy J.;
Brewer, Kathryn M.;
Berbari, Nicolas F.;
Kesterson, Robert A.;
Yoder, Bradley K.

Publication type:

Article

GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail.

Published in:

Developmental Dynamics, 2011, v. 240, n. 3, p. 723, doi. 10.1002/dvdy.22563

By:

Kierszenbaum, Abraham L.;
Rivkin, Eugene;
Tres, Laura L.;
Yoder, Bradley K.;
Haycraft, Courtney J.;
Bornens, Michel;
Rios, Rosa M.

Publication type:

Article

Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines.

Published in:

Developmental Dynamics, 2008, v. 237, n. 8, p. 2039, doi. 10.1002/dvdy.21610

By:

Nielsen, Sonja K.;
Møllgård, Kjeld;
Clement, Christian A.;
Veland, Iben R.;
Awan, Aashir;
Yoder, Bradley K.;
Novak, Ivana;
Christensen, Søren Tvorup

Publication type:

Article

The Oak Ridge Polycystic Kidney mouse: Modeling ciliopathies of mice and men.

Published in:

Developmental Dynamics, 2008, v. 237, n. 8, p. 1960, doi. 10.1002/dvdy.21515

By:

Lehman, Jonathan M.;
Michaud, Edward J.;
Schoeb, Trenton R.;
Aydin-Son, Yesim;
Miller, Michael;
Yoder, Bradley K.

Publication type:

Article

Role for primary cilia in the regulation of mouse ovarian function.

Published in:

Developmental Dynamics, 2008, v. 237, n. 8, p. 2053, doi. 10.1002/dvdy.21612

By:

Johnson, Ellen T.;
Nicola, Teodora;
Roarty, Kevin;
Yoder, Bradley K.;
Haycraft, Courtney J.;
Serra, Rosa

Publication type:

Article

Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 36, p. 9780, doi. 10.1523/JNEUROSCI.5586-06.2007

By:

Chizhikov, Victor V.;
Davenport, James;
Qihong Zhang;
Shih, Evelyn Kim;
Cabello, Olga A.;
Fuchs, Jannon L.;
Yoder, Bradley K.;
Millen, Kathleen J.

Publication type:

Article

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function.

Published in:

PLoS Genetics, 2005, v. 1, n. 4, p. 480, doi. 10.1371/journal.pgen.0010053

By:

Haycraft, Courtney J.;
Banizs, Boglarka;
Aydin-Son, Yesim;
Qihong Zhang;
Michaud, Edward J.;
Yoder, Bradley K.;
Barsh, Gregory

Publication type:

Article

Works by Yoder, Bradley K.

T cell‐expressed Ift88 is required for proper thymocyte differentiation in mice.

THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia.

Ciliary proteins link basal body polarization to planar cell polarity regulation.

Prioritized polycystic kidney disease drug targets and repurposing candidates from pre-cystic and cystic mouse Pkd2 model gene expression reversion.

MKS and NPHP modules cooperate to establish basal body/transition zone membrane associations and ciliary gate function during ciliogenesis.

Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1<sup>cpk</sup> Mouse.

High-Throughput Genome Editing and Phenotyping Facilitated by High Resolution Melting Curve Analysis.

Hippocampal and Cortical Primary Cilia Are Required for Aversive Memory in Mice.

Quantitative Peptidomics of <i>Purkinje Cell Degeneration</i> Mice.

Mks6 mutations reveal tissue- and cell type-specific roles for the cilia transition zone.

NHE Dysregulation in Cilium Deficient Mouse Renal Principal Cells from orpk Mice.

Autocrine Purinergic Signaling Is Required for Monocilium-driven Signaling.

Characterization of Growth Factor Responsiveness and Alterations in Growth Factor Homeostasis Involved in the Tumorigenic Conversion of Mouse Oval Cells.

A mouse model of BBS identifies developmental and homeostatic effects of BBS5 mutation and identifies novel pituitary abnormalities.

Mutation of Growth Arrest Specific 8 Reveals a Role in Motile Cilia Function and Human Disease.

A Screen for Modifiers of Cilia Phenotypes Reveals Novel MKS Alleles and Uncovers a Specific Genetic Interaction between osm-3 and nphp-4.

Directional Cell Migration and Chemotaxis in Wound Healing Response to PDGF-AA are Coordinated by the Primary Cilium in Fibroblasts.

Evolutionarily conserved genetic interactions between nphp-4 and bbs-5 mutations exacerbate ciliopathy phenotypes.

The tetratricopeptide repeat containing Tg737 gene is a liver neoplasia tumor suppressor gene.

Role for intraflagellar transport in building a functional transition zone.

Urinary T cells correlate with rate of renal function loss in autosomal dominant polycystic kidney disease.

Human transcription factors responsive to initial reprogramming predominantly undergo legitimate reprogramming during fibroblast conversion to iPSCs.

Assessing the pathogenic potential of human Nephronophthisis disease-associated NPHP-4 missense mutations in C. elegans.

Functional correction of renal defects in a mouse model for ARPKD through expression of the cloned wild-type <em>Tg737</em> cDNA.

Increased flux through the mevalonate pathway mediates fibrotic repair without injury.

Loss of the Tg737 protein results in skeletal patterning defects.

An Essential Role for Dermal Primary Cilia in Hair Follicle Morphogenesis.

Microtubule modifications and stability are altered by cilia perturbation and in cystic kidney disease.

A transgenic Alx4‐CreER mouse to analyze anterior limb and nephric duct development.

GMAP210 and IFT88 are present in the spermatid golgi apparatus and participate in the development of the acrosome-acroplaxome complex, head-tail coupling apparatus and tail.

Characterization of primary cilia and Hedgehog signaling during development of the human pancreas and in human pancreatic duct cancer cell lines.

The Oak Ridge Polycystic Kidney mouse: Modeling ciliopathies of mice and men.

Role for primary cilia in the regulation of mouse ovarian function.

Cilia Proteins Control Cerebellar Morphogenesis by Promoting Expansion of the Granule Progenitor Pool.

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function.