Works by Yeo, Giles S. H.

Results: 38

From GWAS to biology: lessons from FTO.

Published in:

Annals of the New York Academy of Sciences, 2011, v. 1220, n. 1, p. 162, doi. 10.1111/j.1749-6632.2010.05903.x

By:

Tung, Yi‐Chun Loraine;
Yeo, Giles S. H.

Publication type:

Article

High Coexpression of the Ghrelin and LEAP2 Receptor GHSR With Pancreatic Polypeptide in Mouse and Human Islets.

Published in:

Endocrinology, 2021, v. 162, n. 10, p. 1, doi. 10.1210/endocr/bqab148

By:

Gupta, Deepali;
Dowsett, Georgina K C;
Mani, Bharath K;
Shankar, Kripa;
Osborne-Lawrence, Sherri;
Metzger, Nathan P;
Lam, Brian Y H;
Yeo, Giles S H;
Zigman, Jeffrey M

Publication type:

Article

Neurochemical Characterization of Brainstem Pro-Opiomelanocortin Cells.

Published in:

Endocrinology, 2020, v. 161, n. 4, p. 1, doi. 10.1210/endocr/bqaa032

By:

Georgescu, Teodora;
Lyons, David;
Doslikova, Barbora;
Garcia, Ana Paula;
Marston, Oliver;
Burke, Luke K;
Chianese, Raffaella;
Lam, Brian Y H;
Yeo, Giles S H;
Rochford, Justin J;
Garfield, Alastair S;
Heisler, Lora K

Publication type:

Article

Fat mass and obesity-related (FTO) shuttles between the nucleus and cytoplasm.

Published in:

Bioscience Reports, 2014, v. 34, n. 5, p. 621, doi. 10.1042/BSR20140111

By:

Gulati, Pawan;
Avezov, Edward;
Ma, Marcella;
Antrobus, Robin;
Lehner, Paul;
O'Rahilly, Stephen;
Yeo, Giles S. H.

Publication type:

Article

Serotonin Activates the Hypothalamic--Pituitary--Adrenal Axis via Serotonin 2C Receptor Stimulation.

Published in:

Journal of Neuroscience, 2007, v. 27, n. 26, p. 6956, doi. 10.1523/JNEUROSCI.2584-06.2007

By:

Heisler, Lora K.;
Pronchuk, Nina;
Nonogaki, Katsunori;
Ligang Zhou;
Raber, Jacob;
Tung, Loraine;
Yeo, Giles S. H.;
O'Rahilly, Stephen;
Colmers, William F.;
Elmquist, Joel K.;
Tecott, Laurence H.

Publication type:

Article

Adult Onset Global Loss of the Fto Gene Alters Body Composition and Metabolism in the Mouse.

Published in:

PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003166

By:

McMurray, Fiona;
Church, Chris D.;
Larder, Rachel;
Nicholson, George;
Wells, Sara;
Teboul, Lydia;
Tung, Y. C. Loraine;
Rimmington, Debra;
Bosch, Fatima;
Jimenez, Veronica;
Yeo, Giles S. H.;
O’Rahilly, Stephen;
Ashcroft, Frances M.;
Coll, Anthony P.;
Cox, Roger D.

Publication type:

Article

PPAR gamma 2 Prevents Lipotoxicity by Controlling Adipose Tissue Expandability and Peripheral Lipid Metabolism.

Published in:

PLoS Genetics, 2007, v. 3, n. 4, p. e64, doi. 10.1371/journal.pgen.0030064

By:

Medina-Gomez, Gema;
Gray, Sarah L.;
Yetukuri, Laxman;
Shimomura, Kenju;
Virtue, Sam;
Campbell, Mark;
Curtis, R. Keira;
Jimenez-Linan, Mercedes;
Blount, Margaret;
Yeo, Giles S. H.;
Lopez, Miguel;
Seppänen-Laakso, Tuulikki;
Ashcroft, Frances M.;
OrešIč, Matej;
Vidal-Puig, Antonio

Publication type:

Article

Hypothalamic loss of Snord116 recapitulates the hyperphagia of Prader-Willi syndrome.

Published in:

2018

By:

Polex-Wolf, Joseph;
Lam, Brian Y. H.;
Larder, Rachel;
Tadross, John;
Rimmington, Debra;
Bosch, Fàtima;
Jiménez Cenzano, Verónica;
Ayuso, Eduard;
Ma, Marcella K. L.;
Rainbow, Kara;
Coll, Anthony P.;
O’Rahilly, Stephen;
Yeo, Giles S. H.;
Lam, Brian Yh;
Cenzano, Verónica Jiménez;
Ma, Marcella Kl;
O'Rahilly, Stephen;
Yeo, Giles Sh

Publication type:

journal article

Impaired prohormone processing: a grand unified theory for features of Prader-Willi syndrome?

Published in:

2017

By:

Polex-Wolf, Joseph;
Yeo, Giles S. H.;
O'Rahilly, Stephen

Publication type:

journal article

Somatic mutations in ATP1A1 and CACNA1D underlie a common subtype of adrenal hypertension.

Published in:

Nature Genetics, 2013, v. 45, n. 9, p. 1055, doi. 10.1038/ng.2716

By:

Azizan, Elena A B;
Poulsen, Hanne;
Tuluc, Petronel;
Zhou, Junhua;
Clausen, Michael V;
Lieb, Andreas;
Maniero, Carmela;
Garg, Sumedha;
Bochukova, Elena G;
Zhao, Wanfeng;
Shaikh, Lalarukh Haris;
Brighton, Cheryl A;
Teo, Ada E D;
Davenport, Anthony P;
Dekkers, Tanja;
Tops, Bas;
Küsters, Benno;
Ceral, Jiri;
Yeo, Giles S H;
Neogi, Sudeshna Guha

Publication type:

Article

DEFLATE Compression Algorithm Corrects for Overestimation of Phylogenetic Diversity by Grantham Approach to Single-Nucleotide Polymorphism Classification.

Published in:

International Journal of Molecular Sciences, 2014, v. 15, n. 5, p. 8491, doi. 10.3390/ijms15058491

By:

Schlosberg, Arran;
Lam, Brian Y. H.;
Yeo, Giles S. H.;
Clifton-Bligh, Roderick J.

Publication type:

Article

Kinetic analysis of FTO (fat mass and obesity-associated) reveals that it is unlikely to function as a sensor for 2-oxoglutarate.

Published in:

Biochemical Journal, 2012, v. 444, n. 2, p. 183, doi. 10.1042/BJ20120065

By:

Marcella, M. A.;
HARDING, Heather P.;
O'RAHILLY, Stephen;
RON, David;
YEO, Giles S. H.

Publication type:

Article

FTO and Obesity: A Problem for a Billion People.

Published in:

Journal of Neuroendocrinology, 2012, v. 24, n. 2, p. 393, doi. 10.1111/j.1365-2826.2011.02254.x

By:

Yeo, Giles S. H.

Publication type:

Article

Dax1 modulates ERα-dependent hypothalamic estrogen sensing in female mice.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38618-y

By:

Ramos-Pittol, Jose M.;
Fernandes-Freitas, Isabel;
Milona, Alexandra;
Manchishi, Stephen M.;
Rainbow, Kara;
Lam, Brian Y. H.;
Tadross, John A.;
Beucher, Anthony;
Colledge, William H.;
Cebola, Inês;
Murphy, Kevin G.;
Miguel-Aliaga, Irene;
Yeo, Giles S. H.;
Dhillo, Waljit S.;
Owen, Bryn M.

Publication type:

Article

Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 46, p. 15464, doi. 10.1523/JNEUROSCI.1800-10.2010

By:

Zivraj, Krishna H.;
Tung, Yi Chun Loraine;
Piper, Michael;
Gumy, Laura;
Fawcett, James W.;
Yeo, Giles S. H.;
Holt, Christine E.

Publication type:

Article

Novel Leptin-Regulated Genes Revealed by Transcriptional Profiling of the Hypothalamic Paraventricular Nucleus.

Published in:

Journal of Neuroscience, 2008, v. 28, n. 47, p. 12419, doi. 10.1523/JNEUROSCI.3412-08.2008

By:

Tung, Yi-Chun Loraine;
Ma, Marcella;
Piper, Sarah;
Coll, Anthony;
O'Rahilly, Stephen;
Yeo, Giles S. H.

Publication type:

Article

Proopiomelanocortin and energy balance: insights from human and murine genetics.

Published in:

2004

By:

Coll, Anthony P;
Farooqi, I Sadaf;
Challis, Benjamin G;
Yeo, Giles S H;
O'Rahilly, Stephen

Publication type:

journal article

Fasting pancreatic polypeptide predicts incident microvascular and macrovascular complications of type 2 diabetes: An observational study.

Published in:

Diabetes/Metabolism Research & Reviews, 2024, v. 40, n. 5, p. 1, doi. 10.1002/dmrr.3829

By:

Sam, Amir H.;
Buckley, Adam J.;
Lam, Brian Y. H.;
Bewick, Gavin A.;
Bech, Paul R.;
Meeran, Karim;
Barakat, Maha T.;
Bloom, Stephen R.;
Yeo, Giles S. H.;
Lessan, Nader G.;
Murphy, Kevin G.

Publication type:

Article

Unraveling the brain regulation of appetite: lessons from genetics.

Published in:

Nature Neuroscience, 2012, v. 15, n. 10, p. 1343, doi. 10.1038/nn.3211

By:

Yeo, Giles S H;
Heisler, Lora K

Publication type:

Article

Central melanocortin signaling regulates cholesterol.

Published in:

Nature Neuroscience, 2010, v. 13, n. 7, p. 779, doi. 10.1038/nn0710-779

By:

Yi-Chun Loraine Tung;
Yeo, Giles S. H.

Publication type:

Article

Melanocortin receptors weigh in.

Published in:

Nature Medicine, 2004, v. 10, n. 4, p. 351, doi. 10.1038/nm0404-351

By:

O'Rahilly, Stephen;
Yeo, Giles S. H.;
Farooqi, I. Sadaf

Publication type:

Article

Low circulating levels of IGF-1 in healthy adults are associated with reduced β-cell function, increased intramyocellular lipid, and enhanced fat utilization during fasting.

Published in:

2014

By:

Thankamony, Ajay;
Capalbo, Donatella;
Marcovecchio, M Loredana;
Sleigh, Alison;
Jørgensen, Sine Wanda;
Hill, Nathan R;
Mooslehner, Katrin;
Yeo, Giles S H;
Bluck, Les;
Juul, Anders;
Vaag, Allan;
Dunger, David B

Publication type:

journal article

Breaking our daily "ultra-processed" bread.

Published in:

PLoS Medicine, 2024, v. 21, n. 7, p. 1, doi. 10.1371/journal.pmed.1004437

By:

Yeo, Giles S. H.

Publication type:

Article

Past, present and future strategies to study the genetics of body weight regulation.

Published in:

Briefings in Functional Genomics & Proteomics, 2002, v. 1, n. 3, p. 290, doi. 10.1093/bfgp/1.3.290

By:

Challis, Benjamin G.;
Yeo, Giles S. H.

Publication type:

Article

Maternal diet amplifies the hepatic aging trajectory of Cidea in male mice and leads to the development of fatty liver.

Published in:

FASEB Journal, 2014, v. 28, n. 5, p. 2191, doi. 10.1096/fj.13-242727

By:

Carr, Sarah K.;
Jian-Hua Chen;
Cooper, Wendy N.;
Constância, Miguel;
Yeo, Giles S. H.;
Ozanne, Susan E.

Publication type:

Article

Prevalence of Loss of-Function FTO Mutations in Lean and Obese Individuals.

Published in:

Diabetes, 2010, v. 59, n. 1, p. 311, doi. 10.2337/db09-0703

By:

Meyre, David;
Proulx, Karine;
Kawagoe-Takaki, Hiroko;
Vatin, Vincent;
Gutiérrez-Aguilar, Ruth;
Lyon, Debbie;
Ma, Marcella;
Choquet, Helene;
Horber, Fritz;
Van Hul, Wim;
Van Gaal, Luc;
Balkau, Beverley;
Visvikis-Siest, Sophie;
Pattou, François;
Farooqi, I. Sadaf;
Saudek, Vladimir;
O'Rahilly, Stephen;
Froguel, Philippe;
Sedgwick, Barbara;
Yeo, Giles S. H.

Publication type:

Article

Hyperphagia, Severe Obesity, Impaired Cognitive Function, and Hyperactivity Associated With Functional Loss of One Copy of the Brain-Derived Neurotrophic Factor (BDNF) Gene.

Published in:

Diabetes, 2006, v. 55, n. 12, p. 3366, doi. 10.2337/db06-0550

By:

Gray, Juliette;
Yeo, Giles S. H.;
Cox, James J.;
Morton, Jenny;
Adlam, Anna-Lynne R.;
Keogh, Julia M.;
Yanovski, Jack A.;
El Gharbawy, Areeg;
Han, Joan C.;
Tung, Y. C. Loraine;
Hodges, John R.;
Raymond, F. Lucy;
O'Rahiily, Stephen;
Farooqi, I. Sadaf

Publication type:

Article

Leptin deficiency unmasks the deleterious effects of impaired peroxisome proliferator-activated receptor gamma function (P465L PPARgamma) in mice.

Published in:

2006

By:

Gray, Sarah L.;
Nora, Edoardo Dalla;
Grosse, Johannes;
Manieri, Monia;
Stoeger, Tobias;
Medina-Gomez, Gema;
Burling, Keith;
Wattler, Sigrid;
Russ, Andreas;
Yeo, Giles S. H.;
Chatterjee, V. Krishna;
O'Rahilly, Stephen;
Voshol, Peter J.;
Cinti, Saverio;
Vidal-Puig, Antonio

Publication type:

journal article

Proopiomelanocortin-Deficient Mice Are Hypersensitive to the Adverse Metabolic Effects of Glucocorticoids.

Published in:

Diabetes, 2005, v. 54, n. 8, p. 2269, doi. 10.2337/diabetes.54.8.2269

By:

Coll, Anthony P.;
Challis, Benjamin G.;
López, Miguel;
Piper, Sarah;
Yeo, Giles S. H.;
O'Rahilly, Stephen

Publication type:

Article

Contribution of variants in the small heterodimer partner gene to birthweight, adiposity, and insulin levels: mutational analysis and association studies in multiple populations.

Published in:

2003

By:

Hung, Chiao-Chien Connie;
Farooqi, I. Sadaf;
Ong, Ken;
Luan, Jian'an;
Keogh, Julia M.;
Pembrey, Marcus;
Yeo, Giles S. H.;
Dunger, David;
Wareham, Nicholas J.;
O'Rahilly, Stephen

Publication type:

journal article

OBESITY THERAPY: ALTERING THE ENERGY INTAKE-AND-EXPENDITURE BALANCE SHEET.

Published in:

Nature Reviews Drug Discovery, 2002, v. 1, n. 4, p. 276, doi. 10.1038/nrd770

By:

Crowley, Vivion E. F.;
Yeo, Giles S. H.;
O'Rahilly, Stephen

Publication type:

Article

Hypothalamic-Specific Manipulation of Fto, the Ortholog of the Human Obesity Gene FTO, Affects Food Intake in Rats.

Published in:

PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008771

By:

Tung, Yi-Chun Loraine;
Ayuso, Eduard;
Xiaoye Shan;
Bosch, Fatima;
O'Rahilly, Stephen;
Coll, Anthony P.;
Yeo, Giles S. H.

Publication type:

Article

Contributions of Function-Altering Variants in Genes Implicated in Pubertal Timing and Body Mass for Self-Limited Delayed Puberty.

Published in:

2017

By:

Howard, Sasha R;
Guasti, Leonardo;
Poliandri, Ariel;
David, Alessia;
Cabrera, Claudia P;
Barnes, Michael R;
Wehkalampi, Karoliina;
O'Rahilly, Stephen;
Aiken, Catherine E;
Coll, Anthony P;
Ma, Marcella;
Rimmington, Debra;
Yeo, Giles S H;
Dunkel, Leo

Publication type:

journal article

Selective rab11 transport and the intrinsic regenerative ability of CNS axons.

Published in:

eLife, 2017, p. 1, doi. 10.7554/eLife.26956.001

By:

Koseki, Hiroaki;
Donegá, Matteo;
Lam, Brian Y. H.;
Petrova, Veselina;
van Erp, Susan;
Yeo, Giles S. H.;
Kwok, Jessica C. F.;
ffrench-Constant, Charles;
Eva, Richard;
Fawcett, James W.

Publication type:

Article

Murine neuronatin deficiency is associated with a hypervariable food intake and bimodal obesity.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-96278-8

By:

Cimino, Irene;
Rimmington, Debra;
Tung, Y. C. Loraine;
Lawler, Katherine;
Larraufie, Pierre;
Kay, Richard G.;
Virtue, Samuel;
Lam, Brian Y. H.;
Fagnocchi, Luca;
Ma, Marcella K. L.;
Saudek, Vladimir;
Zvetkova, Ilona;
Vidal-Puig, Antonio;
Yeo, Giles S. H.;
Farooqi, I. Sadaf;
Pospisilik, J. Andrew;
Gribble, Fiona M.;
Reimann, Frank;
O'Rahilly, Stephen;
Coll, Anthony P.

Publication type:

Article

Biallelic Mutations in P4HTM Cause Syndromic Obesity.

Published in:

Diabetes, 2023, v. 72, n. 9, p. 1228, doi. 10.2337/db22-1017

By:

Saeed, Sadia;
Lijiao Ning;
Badreddine, Alaa;
Mirza, Muhammad Usman;
Boissel, Mathilde;
Khanam, Roohia;
Manzoor, Jaida;
Janjua, Qasim M.;
Khan, Waqas I.;
Toussaint, Bénédicte;
Vaillant, Emmanuel;
Amanzougarene, Souhila;
Derhourhi, Mehdi;
Trant, John F.;
Siegert, Anna-Maria;
Lam, Brian Y. H.;
Yeo, Giles S. H.;
Chabraoui, Layachi;
Touzani, Asmae;
Kulkarni, Abhishek

Publication type:

Article

Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling.

Published in:

2019

By:

Larraufie, Pierre;
Kay, Richard G.;
Galvin, Sam G.;
Miedzybrodzka, Emily L.;
Glass, Leslie L.;
Ma, Marcella K. L.;
Lam, Brian;
Yeo, Giles S. H.;
Chiarugi, Davide;
Reimann, Frank;
Gribble, Fiona M.;
Roberts, Geoffrey P.;
Richards, Paul;
Hardwick, Richard H.;
Scharfmann, Raphaël;
Leiter, Andrew;
Li, H. Joyce

Publication type:

journal article

IMPROVE 2022 International Meeting on Pathway‐Related Obesity: Vision of Excellence.

Published in:

Clinical Obesity, 2024, v. 14, n. 3, p. 1, doi. 10.1111/cob.12659

By:

Kühnen, Peter;
Argente, Jesús;
Clément, Karine;
Dollfus, Hélène;
Dubern, Béatrice;
Farooqi, Sadaf;
de Groot, Corjan;
Grüters, Annette;
Holm, Jens‐Christian;
Hopkins, Mark;
Kleinendorst, Lotte;
Körner, Antje;
Meeker, David;
Rydén, Mikael;
von Schnurbein, Julia;
Tschöp, Matthias;
Yeo, Giles S. H.;
Zorn, Stefanie;
Wabitsch, Martin

Publication type:

Article