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Evaluation of the Pharmacokinetics of Metformin Following Coadministration With Doravirine in Healthy Volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2020, v. 9, n. 1, p. 107, doi. 10.1002/cpdd.685
By:
- Sanchez, Rosa I.;
- Yee, Ka Lai;
- Fan, Li;
- Cislak, Dawn;
- Martell, Maureen;
- Jordan, Heather R.;
- Iwamoto, Marian;
- Khalilieh, Sauzanne
Publication type:
Article
Assessment of Bezlotoxumab Immunogenicity.
Published in:
Clinical Pharmacology in Drug Development, 2020, v. 9, n. 3, p. 330, doi. 10.1002/cpdd.729
By:
- Montgomery, Diana L.;
- Matthews, Randolph P.;
- Yee, Ka Lai;
- Tobias, Lori M.;
- Dorr, Mary Beth;
- Wrishko, Rebecca E.
Publication type:
Article
PBPK-PD modeling for the preclinical development and clinical translation of tau antibodies for Alzheimer's disease.
Published in:
Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.867457
By:
- Bloomingdale, Peter;
- Bumbaca-Yadav, Daniela;
- Sugam, Jonathan;
- Grauer, Steve;
- Smith, Brad;
- Antonenko, Svetlana;
- Judo, Michael;
- Azadi, Glareh;
- Ka Lai Yee
Publication type:
Article
Orexin 2 Receptor Antagonism is Sufficient to Promote NREM and REM Sleep from Mouse to Man.
Published in:
Scientific Reports, 2016, p. 27147, doi. 10.1038/srep27147
By:
- Gotter, Anthony L.;
- Forman, Mark S.;
- Harrell, Charles M.;
- Stevens, Joanne;
- Svetnik, Vladimir;
- Yee, Ka Lai;
- Li, Xiaodong;
- Roecker, Anthony J.;
- Fox, Steven V.;
- Tannenbaum, Pamela L.;
- Garson, Susan L.;
- Lepeleire, Inge De;
- Calder, Nicole;
- Rosen, Laura;
- Struyk, Arie;
- Coleman, Paul J.;
- Herring, W. Joseph;
- Renger, John J.;
- Winrow, Christopher J.
Publication type:
Article
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold.
Published in:
BMC Neuroscience, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2202-14-90
By:
- Gotter, Anthony L.;
- Winrow, Christopher J.;
- Brunner, Joseph;
- Garson, Susan L.;
- Fox, Steven V.;
- Binns, Jacquelyn;
- Harrell, Charles M.;
- Donghui Cui;
- Ka Lai Yee;
- Mark Stiteler, Mark Stiteler;
- Stevens, Joanne;
- Savitz, Alan;
- Tannenbaum, Pamela L.;
- Tye, Spencer J.;
- McDonald, Terrence;
- Leon Yao;
- Kuduk, Scott D.;
- Uslaner, Jason;
- Coleman, Paul J.;
- Renger, John J.
Publication type:
Article
The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold.
Published in:
2013
By:
- Gotter, Anthony L;
- Winrow, Christopher J;
- Brunner, Joseph;
- Garson, Susan L;
- Fox, Steven V;
- Binns, Jacquelyn;
- Harrell, Charles M;
- Cui, Donghui;
- Yee, Ka Lai;
- Stiteler, Mark;
- Stevens, Joanne;
- Savitz, Alan;
- Tannenbaum, Pamela L;
- Tye, Spencer J;
- McDonald, Terrence;
- Yao, Leon;
- Kuduk, Scott D;
- Uslaner, Jason;
- Coleman, Paul J;
- Renger, John J
Publication type:
journal article
Predicting vaccine effectiveness against invasive pneumococcal disease in children using immunogenicity data.
Published in:
NPJ Vaccines, 2022, v. 7, n. 1, p. 1, doi. 10.1038/s41541-022-00538-1
By:
- Ryman, Josiah;
- Weaver, Jessica;
- Hu, Tianyan;
- Weinberger, Daniel M.;
- Yee, Ka Lai;
- Sachs, Jeffrey R.
Publication type:
Article
Pharmacokinetics, safety and tolerability of long‐acting parenteral intramuscular injection formulations of doravirine.
Published in:
Journal of Clinical Pharmacy & Therapeutics, 2020, v. 45, n. 5, p. 1098, doi. 10.1111/jcpt.13182
By:
- Yee, Ka Lai;
- Mittal, Sachin;
- Fan, Li;
- Triantafyllou, Ilias;
- Dockendorf, Marissa F.;
- Fackler, Paul H.;
- Stoch, S. Aubrey;
- Khalilieh, Sauzanne G.;
- Iwamoto, Marian
Publication type:
Article
Clinical Pharmacokinetics of the Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor Doravirine: An Assessment of the Effect of Patient Characteristics and Drug–Drug Interactions.
Published in:
Clinical Drug Investigation, 2020, v. 40, n. 10, p. 927, doi. 10.1007/s40261-020-00934-2
By:
- Khalilieh, Sauzanne;
- Yee, Ka Lai;
- Sanchez, Rosa;
- Stoch, S. Aubrey;
- Wenning, Larissa;
- Iwamoto, Marian
Publication type:
Article
Correction to: Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.
Published in:
2019
By:
- Wrishko, Rebecca E.;
- McCrea, Jacqueline B.;
- Yee, Ka Lai;
- Liu, Wen;
- Panebianco, Deborah;
- Mangin, Eric;
- Chakravarthy, Manu;
- Martinez-Cantarin, Maria P.;
- Kraft, Walter K.
Publication type:
Correction Notice
Effect of CYP3A Inhibition and Induction on the Pharmacokinetics of Suvorexant: Two Phase I, Open-Label, Fixed-Sequence Trials in Healthy Subjects.
Published in:
Clinical Drug Investigation, 2019, v. 39, n. 5, p. 441, doi. 10.1007/s40261-019-00764-x
By:
- Wrishko, Rebecca E.;
- McCrea, Jacqueline B.;
- Yee, Ka Lai;
- Liu, Wen;
- Panebianco, Deborah;
- Mangin, Eric;
- Chakravarthy, Manu;
- Martinez-Cantarin, Maria P.;
- Kraft, Walter K.
Publication type:
Article
Safety, Tolerability, and Pharmacokinetics of Suvorexant: A Randomized Rising-Dose Trial in Healthy Men.
Published in:
Clinical Drug Investigation, 2018, v. 38, n. 7, p. 631, doi. 10.1007/s40261-018-0650-4
By:
- Yee, Ka Lai;
- McCrea, Jacqueline;
- Panebianco, Deborah;
- Liu, Wen;
- Lewis, Nicole;
- Cabalu, Tamara;
- Ramael, Steven;
- Wrishko, Rebecca E.
Publication type:
Article
Dealing With Variable Drug Exposure Due to Variable Hepatic Metabolism: A Proof‐of‐Concept Application of Liquid Biopsy in Renal Impairment.
Published in:
Clinical Pharmacology & Therapeutics, 2024, v. 116, n. 3, p. 814, doi. 10.1002/cpt.3291
By:
- Rostami‐Hodjegan, Amin;
- Al‐Majdoub, Zubida M.;
- von Grabowiecki, Yannick;
- Yee, Ka Lai;
- Sahoo, Sudhakar;
- Breitwieser, Wolfgang;
- Galetin, Aleksandra;
- Gibson, Christopher;
- Achour, Brahim
Publication type:
Article
Coproporphyrin I as an Endogenous Biomarker to Detect Reduced OATP1B Activity and Shift in Elimination Route in Chronic Kidney Disease.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 3, p. 615, doi. 10.1002/cpt.2672
By:
- Takita, Hiroyuki;
- Scotcher, Daniel;
- Chu, Xiaoyan;
- Yee, Ka Lai;
- Ogungbenro, Kayode;
- Galetin, Aleksandra
Publication type:
Article
A Disease Progression Model to Quantify the Nonmotor Symptoms of Parkinson's Disease in Participants With Leucine‐Rich Repeat Kinase 2 Mutation.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 2, p. 508, doi. 10.1002/cpt.2277
By:
- Ahamadi, Malidi;
- Mehrotra, Nitin;
- Hanan, Nathan;
- Lai Yee, Ka;
- Gheyas, Ferdous;
- Anton, Judith;
- Bani, Massimo;
- Boroojerdi, Babak;
- Smit, Hans;
- Weidemann, Jonas;
- Macha, Sreeraj;
- Thuillier, Vincent;
- Chen, Chao;
- Yang, Minhua;
- Williams‐Gray, Caroline H.;
- Stebbins, Glenn T.;
- Pagano, Gennaro;
- Hang, Yaming;
- Marek, Kenneth;
- Venuto, Charles S.
Publication type:
Article
A Microdose Cocktail to Evaluate Drug Interactions in Patients with Renal Impairment.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 109, n. 2, p. 403, doi. 10.1002/cpt.1998
By:
- Tatosian, Daniel A.;
- Yee, Ka Lai;
- Zhang, Zufei;
- Mostoller, Kate;
- Paul, Erina;
- Sutradhar, Santosh;
- Larson, Patrick;
- Chhibber, Aparna;
- Wen, Jianzhong;
- Wang, Ya‐Juan;
- Lassman, Michael;
- Latham, Andrew H.;
- Pang, Jianmei;
- Crumley, Tami;
- Gillespie, Anne;
- Marricco, Nadia Cardillo;
- Marenco, Ted;
- Murphy, Matthew;
- Lasseter, Kenneth C.;
- Marbury, Thomas C.
Publication type:
Article
A time-to-event analysis of the exposure–response relationship for bezlotoxumab concentrations and CDI recurrence.
Published in:
Journal of Pharmacokinetics & Pharmacodynamics, 2020, v. 47, n. 2, p. 121, doi. 10.1007/s10928-019-09660-5
By:
- Yee, Ka Lai;
- Kleijn, Huub Jan;
- Zajic, Stefan;
- Dorr, Mary Beth;
- Wrishko, Rebecca E.
Publication type:
Article
Erratum to: A Two-Way Steady-State Pharmacokinetic Interaction Study of Doravirine (MK-1439) and Dolutegravir.
Published in:
2017
By:
- Anderson, Matt;
- Khalilieh, Sauzanne;
- Yee, Ka;
- Liu, Rachael;
- Fan, Li;
- Rizk, Matthew;
- Shah, Vedangi;
- Hussaini, Azra;
- Song, Ivy;
- Ross, Lisa;
- Butterton, Joan;
- Anderson, Matt S;
- Yee, Ka Lai;
- Rizk, Matthew L;
- Ross, Lisa L;
- Butterton, Joan R
Publication type:
journal article
A Two-Way Steady-State Pharmacokinetic Interaction Study of Doravirine (MK-1439) and Dolutegravir.
Published in:
2017
By:
- Anderson, Matt;
- Khalilieh, Sauzanne;
- Yee, Ka;
- Liu, Rachael;
- Fan, Li;
- Rizk, Matthew;
- Shah, Vedangi;
- Hussaini, Azra;
- Song, Ivy;
- Ross, Lisa;
- Butterton, Joan;
- Anderson, Matt S;
- Yee, Ka Lai;
- Rizk, Matthew L;
- Ross, Lisa L;
- Butterton, Joan R
Publication type:
journal article
Comparative Bioavailability of Oral Granule Formulations of the HIV Antiretroviral Drugs Doravirine, Lamivudine, and Tenofovir Disoproxil Fumarate.
Published in:
AAPS PharmSciTech, 2020, v. 21, n. 3, p. 1, doi. 10.1208/s12249-020-1630-6
By:
- Yee, Ka Lai;
- DiBenedetto, Adrienne;
- Fan, Li;
- Khalilieh, Sauzanne;
- Triantafyllou, Ilias;
- Vallee, Marie-Helene;
- Fackler, Paul;
- Stoch, S. Aubrey;
- Iwamoto, Marian
Publication type:
Article
Physiologically Based Pharmacokinetic Modeling of Doravirine and Its Major Metabolite to Support Dose Adjustment With Rifabutin.
Published in:
Journal of Clinical Pharmacology, 2021, v. 61, n. 3, p. 394, doi. 10.1002/jcph.1747
By:
- Yee, Ka Lai;
- Cabalu, Tamara D.;
- Kuo, Yuhsin;
- Fillgrove, Kerry L.;
- Liu, Yang;
- Triantafyllou, Ilias;
- McClain, Sasha;
- Dreyer, Daniel;
- Wenning, Larissa;
- Stoch, S. Aubrey;
- Iwamoto, Marian;
- Sanchez, Rosa I.;
- Khalilieh, Sauzanne G.
Publication type:
Article
A Study to Evaluate Doravirine Pharmacokinetics When Coadministered With Acid‐Reducing Agents.
Published in:
Journal of Clinical Pharmacology, 2019, v. 59, n. 8, p. 1093, doi. 10.1002/jcph.1399
By:
- Khalilieh, Sauzanne G.;
- Yee, Ka Lai;
- Sanchez, Rosa I.;
- Fan, Li;
- Vaynshteyn, Kate;
- Deschamps, Kathleen;
- Martell, Maureen;
- Jordan, Heather R.;
- Iwamoto, Marian
Publication type:
Article
Multiple Doses of Rifabutin Reduce Exposure of Doravirine in Healthy Subjects.
Published in:
Journal of Clinical Pharmacology, 2018, v. 58, n. 8, p. 1044, doi. 10.1002/jcph.1103
By:
- Khalilieh, Sauzanne G.;
- Yee, Ka Lai;
- Sanchez, Rosa I.;
- Liu, Rachel;
- Fan, Li;
- Martell, Maureen;
- Jordan, Heather;
- Iwamoto, Marian
Publication type:
Article
Evaluation of Model‐Based Prediction of Pharmacokinetics in the Renal Impairment Population.
Published in:
Journal of Clinical Pharmacology, 2018, v. 58, n. 3, p. 364, doi. 10.1002/jcph.1022
By:
- Yee, Ka Lai;
- Li, Mengyao;
- Cabalu, Tamara;
- Sahasrabudhe, Vaishali;
- Lin, Jian;
- Zhao, Ping;
- Jadhav, Pravin
Publication type:
Article
Moderate Hepatic Impairment Does Not Affect Doravirine Pharmacokinetics.
Published in:
Journal of Clinical Pharmacology, 2017, v. 57, n. 6, p. 777, doi. 10.1002/jcph.857
By:
- Khalilieh, Sauzanne;
- Yee, Ka Lai;
- Liu, Rachael;
- Fan, Li;
- Sanchez, Rosa I.;
- Auger, Patrice;
- Triantafyllou, Ilias;
- Stypinski, Daria;
- Lasseter, Kenneth C.;
- Marbury, Thomas;
- Iwamoto, Marian
Publication type:
Article
Psychomotor effects, pharmacokinetics and safety of the orexin receptor antagonist suvorexant administered in combination with alcohol in healthy subjects.
Published in:
2015
By:
- Sun, Hong;
- Yee, Ka Lai;
- Gill, Sean;
- Liu, Wen;
- Li, Xiaodong;
- Panebianco, Deborah;
- Mangin, Eric;
- Morrison, Dennis;
- McCrea, Jacqueline;
- Wagner, John A.;
- Troyer, Matthew D.
Publication type:
journal article

Found: 26