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Glioma cells require one-carbon metabolism to survive glutamine starvation.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-020-01114-1
By:
- Tanaka, Kazuhiro;
- Sasayama, Takashi;
- Nagashima, Hiroaki;
- Irino, Yasuhiro;
- Takahashi, Masatomo;
- Izumi, Yoshihiro;
- Uno, Takiko;
- Satoh, Naoko;
- Kitta, Akane;
- Kyotani, Katsusuke;
- Fujita, Yuichi;
- Hashiguchi, Mitsuru;
- Nakai, Tomoaki;
- Kohta, Masaaki;
- Uozumi, Yoichi;
- Shinohara, Masakazu;
- Hosoda, Kohkichi;
- Bamba, Takeshi;
- Kohmura, Eiji
Publication type:
Article
Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry.
Published in:
Journal of Gastroenterology, 2012, v. 47, n. 1, p. 9, doi. 10.1007/s00535-011-0493-8
By:
- Yoshida, Masaru;
- Hatano, Naoya;
- Nishiumi, Shin;
- Irino, Yasuhiro;
- Izumi, Yoshihiro;
- Takenawa, Tadaomi;
- Azuma, Takeshi
Publication type:
Article
Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis.
Published in:
Arthritis Research & Therapy, 2017, v. 19, p. 1, doi. 10.1186/s13075-017-1283-3
By:
- Soshi Takahashi;
- Saegusa, Jun;
- Sho Sendo;
- Takaichi Okano;
- Kengo Akashi;
- Yasuhiro Irino;
- Akio Morinobu
Publication type:
Article
Highly specific plasma β‐amyloid assays on the fully automated platform predict brain β‐amyloid pathology determined by a Centiloid threshold of amyloid PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068727
By:
- Yamashita, Kazuto;
- Miura, Masahiro;
- Watanabe, Shunsuke;
- Ishiki, Kengo;
- Arimatsu, Yuji;
- Kawahira, Junoko;
- Kubo, Toshiko;
- Sasaki, Katsutaka;
- Arai, Takayuki;
- Hagino, Kei;
- Irino, Yasuhiro;
- Nagai, Kota;
- Verbel, David;
- Koyama, Akihiko;
- Dhadda, Shobha;
- Niiro, Hayato;
- Iwanaga, Shigeki;
- Sato, Toshiyuki;
- Yoshida, Tomokazu;
- Iwata, Atsushi
Publication type:
Article
Characterization of AD pathology based on plasma biomarkers measured by a fully automated immunoassay system (HISCLTM series).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.057571
By:
- Watanabe, Shunsuke;
- Ishiki, Kengo;
- Yamashita, Kazuto;
- Lukaszewska, Teresa;
- Miura, Masahiro;
- Irino, Yasuhiro;
- Iwanaga, Shigeki;
- Yoshida, Tomokazu
Publication type:
Article
Effects of Intermediates between Vitamins K2 and K3 on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity.
Published in:
International Journal of Molecular Sciences, 2011, v. 12, n. 2, p. 1115, doi. 10.3390/ijms12021115
By:
- Yoshiyuki Mizushina;
- Maeda, Jun;
- Irino, Yasuhiro;
- Nishida, Masayuki;
- Nishiumi, Shin;
- Kondo, Yasuyuki;
- Nishio, Kazuyuki;
- Kuramochi, Kouji;
- Tsubaki, Kazunori;
- Kuriyama, Isoko;
- Azuma, Takeshi;
- Yoshida, Hiromi;
- Yoshida, Masaru
Publication type:
Article
P2Y12 receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP.
Published in:
Glia, 2010, v. 58, n. 7, p. 790, doi. 10.1002/glia.20963
By:
- Ohsawa, Keiko;
- Irino, Yasuhiro;
- Sanagi, Tomomi;
- Nakamura, Yasuko;
- Suzuki, Eri;
- Inoue, Kazuhide;
- Kohsaka, Shinichi
Publication type:
Article
Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis.
Published in:
Glia, 2007, v. 55, n. 6, p. 604, doi. 10.1002/glia.20489
By:
- Ohsawa, Keiko;
- Irino, Yasuhiro;
- Nakamura, Yasuko;
- Akazawa, Chihiro;
- Inoue, Kazuhide;
- Kohsaka, Shinichi
Publication type:
Article
Immunogenicity after vaccination of COVID-19 vaccines in patients with cancer: a prospective, single center, observational study.
Published in:
International Journal of Clinical Oncology, 2024, v. 29, n. 4, p. 386, doi. 10.1007/s10147-024-02470-x
By:
- Katsuya, Yuki;
- Yoshida, Tatsuya;
- Takashima, Atsuo;
- Yonemori, Kan;
- Ohba, Akihiro;
- Yazaki, Shu;
- Yagishita, Shigehiro;
- Nakahama, Hiroko;
- Kobayashi, Osamu;
- Yanagida, Masatoshi;
- Irino, Yasuhiro;
- Hamada, Akinobu;
- Yamamoto, Noboru
Publication type:
Article
2-Aminobutyric acid modulates glutathione homeostasis in the myocardium.
Published in:
Scientific Reports, 2016, p. 36749, doi. 10.1038/srep36749
By:
- Irino, Yasuhiro;
- Toh, Ryuji;
- Nagao, Manabu;
- Mori, Takeshige;
- Honjo, Tomoyuki;
- Shinohara, Masakazu;
- Tsuda, Shigeyasu;
- Nakajima, Hideto;
- Satomi-Kobayashi, Seimi;
- Shinke, Toshiro;
- Tanaka, Hidekazu;
- Ishida, Tatsuro;
- Miyata, Okiko;
- Hirata, Ken-ichi
Publication type:
Article
Inhibitory Effects of Glycyrrhetinic Acid on DNA Polymerase and Inflammatory Activities.
Published in:
Evidence-based Complementary & Alternative Medicine (eCAM), 2012, v. 2012, p. 1, doi. 10.1155/2012/650514
By:
- Ishida, Tsukasa;
- Mizushina, Yoshiyuki;
- Yagi, Saori;
- Irino, Yasuhiro;
- Nishiumi, Shin;
- Miki, Ikuya;
- Kondo, Yasuyuki;
- Mizuno, Shigeto;
- Yoshida, Hiromi;
- Azuma, Takeshi;
- Yoshida, Masaru
Publication type:
Article
Peripheral blood metabolome predicts mood change-related activity in mouse model of bipolar disorder.
Published in:
Molecular Brain, 2019, v. 12, n. 1, p. 1, doi. 10.1186/s13041-019-0527-3
By:
- Hagihara, Hideo;
- Horikawa, Tomoyasu;
- Irino, Yasuhiro;
- Nakamura, Hironori K.;
- Umemori, Juzoh;
- Shoji, Hirotaka;
- Yoshida, Masaru;
- Kamitani, Yukiyasu;
- Miyakawa, Tsuyoshi
Publication type:
Article
Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes.
Published in:
Metabolomics, 2015, v. 11, n. 5, p. 1277, doi. 10.1007/s11306-015-0784-9
By:
- Yokoi, Norihide;
- Beppu, Masayuki;
- Yoshida, Eri;
- Hoshikawa, Ritsuko;
- Hidaka, Shihomi;
- Matsubara, Toshiya;
- Shinohara, Masami;
- Irino, Yasuhiro;
- Hatano, Naoya;
- Seino, Susumu
Publication type:
Article
GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis.
Published in:
Inflammation Research, 2011, v. 60, n. 9, p. 831, doi. 10.1007/s00011-011-0340-7
By:
- Ooi, Makoto;
- Nishiumi, Shin;
- Yoshie, Tomoo;
- Shiomi, Yuuki;
- Kohashi, Michitaka;
- Fukunaga, Ken;
- Nakamura, Shiro;
- Matsumoto, Takayuki;
- Hatano, Naoya;
- Shinohara, Masakazu;
- Irino, Yasuhiro;
- Takenawa, Tadaomi;
- Azuma, Takeshi;
- Yoshida, Masaru
Publication type:
Article
Quantification of Amyloid-β in Plasma by Simple and Highly Sensitive Immunoaffinity Enrichment and LC-MS/MS Assay.
Published in:
Journal of Applied Laboratory Medicine, 2021, v. 6, n. 4, p. 834, doi. 10.1093/jalm/jfaa225
By:
- Takuya Iino;
- Shunsuke Watanabe;
- Kazuto Yamashita;
- Eiya Tamada;
- Takehiro Hasegawa;
- Yasuhiro Irino;
- Shigeki Iwanaga;
- Amane Harada;
- Kenta Noda;
- Kouzou Suto;
- Tomokazu Yoshida
Publication type:
Article
Cholesterol Uptake Capacity: A New Measure of HDL Functionality for Coronary Risk Assessment.
Published in:
Journal of Applied Laboratory Medicine, 2017, p. 186, doi. 10.1373/jalm.2016.022913
By:
- Amane Harada;
- Ryuji Toh;
- Katsuhiro Murakami;
- Kiriyama, Maria;
- Keiko Yoshikawa;
- Keiko Miwa;
- Takuya Kubo;
- Yasuhiro Irino;
- Kenta Mori;
- Nobuaki Tanaka;
- Kunihiro Nishimura;
- Tatsuro Ishida;
- Ken-ichi Hirata
Publication type:
Article
CBMT-25. ANTI-TUMOR EFFECT OF VEGF INHIBITOR PLUS KETOGENIC DIET THERAPY FOR GLIOBLASTOMA.
Published in:
Neuro-Oncology, 2018, v. 20, p. vi37, doi. 10.1093/neuonc/noy148.144
By:
- Maeyama, Masahiro;
- Sasayama, Takashi;
- Tanaka, Kazuhiro;
- Irino, Yasuhiro;
- Nishihara, Masamitsu;
- Tanaka, Hirotomo;
- Nakamizo, Satoshi;
- Kohmura, Eiji
Publication type:
Article
CBMT-10. GLUTAMINE DEPRIVATION ALTERS ONE-CARBON METABOLISM TO MAINTAIN GLIOMA CELL SURVIVAL.
Published in:
Neuro-Oncology, 2018, v. 20, p. vi34, doi. 10.1093/neuonc/noy148.129
By:
- Tanaka, Kazuhiro;
- Sasayama, Takashi;
- Uno, Takiko;
- Maeyama, Masahiro;
- Fujita, Yuichi;
- Irino, Yasuhiro;
- Kohmura, Eiji
Publication type:
Article
Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.
Published in:
Neuro-Oncology, 2016, v. 18, n. 11, p. 1559, doi. 10.1093/neuonc/now090
By:
- Hiroaki Nagashima;
- Kazuhiro Tanaka;
- Takashi Sasayama;
- Yasuhiro Irino;
- Naoko Sato;
- Yukiko Takeuchi;
- Katsusuke Kyotani;
- Akitake Mukasa;
- Katsu Mizukawa;
- Junichi Sakata;
- Yusuke Yamamoto;
- Kohkichi Hosoda;
- Tomoo Itoh;
- Ryohei Sasaki;
- Eiji Kohmura
Publication type:
Article
Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.
Published in:
Journal of Clinical Investigation, 2015, v. 125, n. 4, p. 1591, doi. 10.1172/JCI78239
By:
- Kazuhiro Tanaka;
- Takashi Sasayama;
- Yasuhiro Irino;
- Kumi Takata;
- Hiroaki Nagashima;
- Naoko Satoh;
- Katsusuke Kyotani;
- Takashi Mizowaki;
- Taichiro Imahori;
- Yasuo Ejima;
- Kenta Masui;
- Gini, Beatrice;
- Huijun Yang;
- Kohkichi Hosoda;
- Ryohei Sasaki;
- Mischel, Paul S.;
- Eiji Kohmura
Publication type:
Article
Phospholipase Cδ4 Associates with Glutamate Receptor Interacting Protein 1 in Testis.
Published in:
Journal of Biochemistry, 2005, v. 138, n. 4, p. 451, doi. 10.1093/jb/mvi135
By:
- Irino, Yasuhiro;
- Ichinohe, Manabu;
- Nakamura, Yoshikazu;
- Nakahara, Masamichi;
- Fukami, Kiyoko
Publication type:
Article
Behavioral effects of long‐term oral administration of aluminum ammonium sulfate in male and female C57BL/6J mice.
Published in:
Neuropsychopharmacology Reports, 2018, v. 38, n. 1, p. 18, doi. 10.1002/npr2.12002
By:
- Shoji, Hirotaka;
- Irino, Yasuhiro;
- Yoshida, Masaru;
- Miyakawa, Tsuyoshi
Publication type:
Article
Impaired Cholesterol-Uptake Capacity of HDL Might Promote Target-Lesion Revascularization by Inducing Neoatherosclerosis After Stent Implantation.
Published in:
2019
By:
- Yuichiro Nagano;
- Hiromasa Otake;
- Takayoshi Toba;
- Koji Kuroda;
- Yuto Shinkura;
- Natsuko Tahara;
- Yoshiro Tsukiyama;
- Kenichi Yanaka;
- Hiroyuki Yamamoto;
- Akira Nagasawa;
- Hiroyuki Onishi;
- Yoichiro Sugizaki;
- Ryo Takeshige;
- Amane Harada;
- Kiriyama, Maria;
- Toshihiko Oshita;
- Yasuhiro Irino;
- Hiroyuki Kawamori;
- Tatsuro Ishida;
- Ryuji Toh
Publication type:
journal article
Metabolic changes and anti-tumor effects of a ketogenic diet combined with anti-angiogenic therapy in a glioblastoma mouse model.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-79465-x
By:
- Maeyama, Masahiro;
- Tanaka, Kazuhiro;
- Nishihara, Masamitsu;
- Irino, Yasuhiro;
- Shinohara, Masakazu;
- Nagashima, Hiroaki;
- Tanaka, Hirotomo;
- Nakamizo, Satoshi;
- Hashiguchi, Mitsuru;
- Fujita, Yuichi;
- Kohta, Masaaki;
- Kohmura, Eiji;
- Sasayama, Takashi
Publication type:
Article
GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients.
Published in:
Journal of Neuro-Oncology, 2013, v. 113, n. 1, p. 65, doi. 10.1007/s11060-013-1090-x
By:
- Nakamizo, Satoshi;
- Sasayama, Takashi;
- Shinohara, Masakazu;
- Irino, Yasuhiro;
- Nishiumi, Shin;
- Nishihara, Masamitsu;
- Tanaka, Hirotomo;
- Tanaka, Kazuhiro;
- Mizukawa, Katsu;
- Itoh, Tomoo;
- Taniguchi, Masaaki;
- Hosoda, Kohkichi;
- Yoshida, Masaru;
- Kohmura, Eiji
Publication type:
Article
GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients.
Published in:
Journal of Neuro-Oncology, 2013, v. 111, n. 3, p. 1, doi. 10.1007/s11060-013-1090-x
By:
- Nakamizo, Satoshi;
- Sasayama, Takashi;
- Shinohara, Masakazu;
- Irino, Yasuhiro;
- Nishiumi, Shin;
- Nishihara, Masamitsu;
- Tanaka, Hirotomo;
- Tanaka, Kazuhiro;
- Mizukawa, Katsu;
- Itoh, Tomoo;
- Taniguchi, Masaaki;
- Hosoda, Kohkichi;
- Yoshida, Masaru;
- Kohmura, Eiji
Publication type:
Article
High-density lipoprotein protects cardiomyocytes from oxidative stress via the PI3K/ mTOR signaling pathway.
Published in:
FEBS Open Bio, 2017, v. 7, n. 9, p. 1402, doi. 10.1002/2211-5463.12279
By:
- Nagao, Manabu;
- Toh, Ryuji;
- Irino, Yasuhiro;
- Nakajima, Hideto;
- Oshita, Toshihiko;
- Tsuda, Shigeyasu;
- Hara, Tetsuya;
- Shinohara, Masakazu;
- Ishida, Tatsuro;
- Hirata, Ken-ichi
Publication type:
Article
Fully automated and highly specific plasma β-amyloid immunoassays predict β-amyloid status defined by amyloid positron emission tomography with high accuracy.
Published in:
Alzheimer's Research & Therapy, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13195-022-01029-0
By:
- Yamashita, Kazuto;
- Miura, Masahiro;
- Watanabe, Shunsuke;
- Ishiki, Kengo;
- Arimatsu, Yuji;
- Kawahira, Junko;
- Kubo, Toshiko;
- Sasaki, Katsutaka;
- Arai, Takayuki;
- Hagino, Kei;
- Irino, Yasuhiro;
- Nagai, Kota;
- Verbel, David;
- Koyama, Akihiko;
- Dhadda, Shobha;
- Niiro, Hayato;
- Iwanaga, Shigeki;
- Sato, Toshiyuki;
- Yoshida, Tomokazu;
- Iwata, Atsushi
Publication type:
Article
Trans-fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll-like receptors.
Published in:
Molecular Nutrition & Food Research, 2015, v. 59, n. 4, p. 729, doi. 10.1002/mnfr.201400537
By:
- Kondo, Kensuke;
- Ishida, Tatsuro;
- Yasuda, Tomoyuki;
- Nakajima, Hideto;
- Mori, Kenta;
- Tanaka, Nobuaki;
- Mori, Takeshige;
- Monguchi, Tomoko;
- Shinohara, Masakazu;
- Irino, Yasuhiro;
- Toh, Ryuji;
- Rikitake, Yoshiyuki;
- Kiyomizu, Kazunobu;
- Tomiyama, Yoshiaki;
- Yamamoto, Junichiro;
- Hirata, Ken‐ichi
Publication type:
Article
Effects of Elaidic Acid on HDL Cholesterol Uptake Capacity.
Published in:
Nutrients, 2021, v. 13, n. 9, p. 3112, doi. 10.3390/nu13093112
By:
- Iino, Takuya;
- Toh, Ryuji;
- Nagao, Manabu;
- Shinohara, Masakazu;
- Harada, Amane;
- Murakami, Katsuhiro;
- Irino, Yasuhiro;
- Nishimori, Makoto;
- Yoshikawa, Sachiko;
- Seto, Yutaro;
- Ishida, Tatsuro;
- Hirata, Ken-ichi
Publication type:
Article
Geranylgeranylacetone attenuates cerebral ischemia-reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study.
Published in:
2021
By:
- Matsuo, Kazuya;
- Hosoda, Kohkichi;
- Tanaka, Jun;
- Yamamoto, Yusuke;
- Imahori, Taichiro;
- Nakai, Tomoaki;
- Irino, Yasuhiro;
- Shinohara, Masakazu;
- Sasayama, Takashi;
- Kohmura, Eiji
Publication type:
journal article

Found: 31

Glioma cells require one-carbon metabolism to survive glutamine starvation.

Diagnosis of gastroenterological diseases by metabolome analysis using gas chromatography-mass spectrometry.

Glutaminase 1 plays a key role in the cell growth of fibroblast-like synoviocytes in rheumatoid arthritis.

Highly specific plasma β‐amyloid assays on the fully automated platform predict brain β‐amyloid pathology determined by a Centiloid threshold of amyloid PET.

Characterization of AD pathology based on plasma biomarkers measured by a fully automated immunoassay system (HISCL<sup>TM</sup> series).

Effects of Intermediates between Vitamins K<sub>2</sub> and K<sub>3</sub> on Mammalian DNA Polymerase Inhibition and Anti-Inflammatory Activity.

P2Y<sub>12</sub> receptor-mediated integrin-β1 activation regulates microglial process extension induced by ATP.

Involvement of P2X<sub>4</sub> and P2Y<sub>12</sub> receptors in ATP-induced microglial chemotaxis.

Immunogenicity after vaccination of COVID-19 vaccines in patients with cancer: a prospective, single center, observational study.

2-Aminobutyric acid modulates glutathione homeostasis in the myocardium.

Inhibitory Effects of Glycyrrhetinic Acid on DNA Polymerase and Inflammatory Activities.

Peripheral blood metabolome predicts mood change-related activity in mouse model of bipolar disorder.

Identification of putative biomarkers for prediabetes by metabolome analysis of rat models of type 2 diabetes.

GC/MS-based profiling of amino acids and TCA cycle-related molecules in ulcerative colitis.

Quantification of Amyloid-β in Plasma by Simple and Highly Sensitive Immunoaffinity Enrichment and LC-MS/MS Assay.

Cholesterol Uptake Capacity: A New Measure of HDL Functionality for Coronary Risk Assessment.

CBMT-25. ANTI-TUMOR EFFECT OF VEGF INHIBITOR PLUS KETOGENIC DIET THERAPY FOR GLIOBLASTOMA.

CBMT-10. GLUTAMINE DEPRIVATION ALTERS ONE-CARBON METABOLISM TO MAINTAIN GLIOMA CELL SURVIVAL.

Diagnostic value of glutamate with 2-hydroxyglutarate in magnetic resonance spectroscopy for IDH1 mutant glioma.

Compensatory glutamine metabolism promotes glioblastoma resistance to mTOR inhibitor treatment.

Phospholipase Cδ4 Associates with Glutamate Receptor Interacting Protein 1 in Testis.

Behavioral effects of long‐term oral administration of aluminum ammonium sulfate in male and female C57BL/6J mice.

Impaired Cholesterol-Uptake Capacity of HDL Might Promote Target-Lesion Revascularization by Inducing Neoatherosclerosis After Stent Implantation.

Metabolic changes and anti-tumor effects of a ketogenic diet combined with anti-angiogenic therapy in a glioblastoma mouse model.

GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients.

GC/MS-based metabolomic analysis of cerebrospinal fluid (CSF) from glioma patients.

High-density lipoprotein protects cardiomyocytes from oxidative stress via the PI3K/ mTOR signaling pathway.

Fully automated and highly specific plasma β-amyloid immunoassays predict β-amyloid status defined by amyloid positron emission tomography with high accuracy.

Trans-fatty acid promotes thrombus formation in mice by aggravating antithrombogenic endothelial functions via Toll-like receptors.

Effects of Elaidic Acid on HDL Cholesterol Uptake Capacity.

Geranylgeranylacetone attenuates cerebral ischemia-reperfusion injury in rats through the augmentation of HSP 27 phosphorylation: a preliminary study.