Works matching AU Yao, Shao Q.

Results: 114

Lysine‐Targeting, Covalent Inhibitors of Bromodomain BD1 of BET Proteins in Live Cells and Animals.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 28, p. 1, doi. 10.1002/anie.202424832

By:

Li, Tao;
Zhang, Wenjie;
Wang, Yiqing;
Xu, Guangyu;
Miao, Fengfei;
Chen, Peng;
Tang, Guanghui;
Ze, Xiaotong;
Xiang, Jing;
Yan, Jiaqian;
Wang, Miaomiao;
Liu, Min;
Wang, Xiaojie;
Tang, Wei;
Yi, Fan;
Zhang, Zhi‐Min;
Wang, Rui;
Yao, Shao Q;
Xie, Yusheng

Publication type:

Article

Lysine‐Targeting, Covalent Inhibitors of Bromodomain BD1 of BET Proteins in Live Cells and Animals.

Published in:

Angewandte Chemie, 2025, v. 137, n. 28, p. 1, doi. 10.1002/ange.202424832

By:

Li, Tao;
Zhang, Wenjie;
Wang, Yiqing;
Xu, Guangyu;
Miao, Fengfei;
Chen, Peng;
Tang, Guanghui;
Ze, Xiaotong;
Xiang, Jing;
Yan, Jiaqian;
Wang, Miaomiao;
Liu, Min;
Wang, Xiaojie;
Tang, Wei;
Yi, Fan;
Zhang, Zhi‐Min;
Wang, Rui;
Yao, Shao Q;
Xie, Yusheng

Publication type:

Article

MSN‐on‐a‐Chip: Cell‐Based Screenings Made Possible on a Small‐Molecule Microarray of Native Natural Products.

Published in:

ChemBioChem, 2018, v. 19, n. 9, p. 986, doi. 10.1002/cbic.201800101

By:

Peng, Bo;
Yu, Changmin;
Du, Shubo;
Liew, Si S.;
Mao, Xin;
Yuan, Peiyan;
Na, Zhenkun;
Yao, Shao Q.

Publication type:

Article

Dynamic Monitoring of Newly Synthesized Proteomes: Up-Regulation of Myristoylated Protein Kinase A During Butyric Acid Induced Apoptosis.

Published in:

Angewandte Chemie, 2011, v. 123, n. 30, p. 6908, doi. 10.1002/ange.201102542

By:

Liu, Kai;
Yang, Peng-Yu;
Na, Zhenkun;
Yao, Shao Q.

Publication type:

Article

Microarray-Assisted High-Throughput Identification of a Cell-Permeable Small-Molecule Binder of 14 -3 -3 Proteins.

Published in:

Angewandte Chemie, 2010, v. 122, n. 37, p. 6678, doi. 10.1002/ange.201003257

By:

Wu, Hao;
Ge, Jingyan;
Yao, Shao Q.

Publication type:

Article

Activity-Based High-Throughput Screening of Enzymes by Using a DNA Microarray.

Published in:

Angewandte Chemie, 2005, v. 117, n. 7, p. 1072, doi. 10.1002/ange.200461612

By:

Yi Hu;
Grace Y. J. Chen;
Shao Q. Yao

Publication type:

Article

Multiplex Imaging and Cellular Target Identification of Kinase Inhibitors via an Affinity-Based Proteome Profiling Approach.

Published in:

Scientific Reports, 2015, p. 7724, doi. 10.1038/srep07724

By:

Pan, Sijun;
Wu, Xiaoyuan;
Li, Zhengqiu;
Yao, Shao Q.;
Hao, Piliang;
Sze, Siu Kwan;
Su, Ying;
Li, Lin

Publication type:

Article

Orthogonal Strategies for Profiling Potential Cellular Targets of Anandamide and Cannabidiol.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 43, p. 1, doi. 10.1002/chem.202300682

By:

Tang, Guanghui;
Lim, Ying‐Jie;
Wang, Wei;
Ye, Zi;
Zhang, Chong‐Jing;
Yao, Shao Q.

Publication type:

Article

A Late-Stage Aryl C--H Olefination Strategy and Its Application Towards Global Proteome Profiling of Δ<sup>8</sup>-Tetrahydrocannabinol.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 29, p. 1, doi. 10.1002/chem.202300531

By:

Ying-Jie Lim;
Guanghui Tang;
Zi Ye;
Chong-Jing Zhang;
Jie Wu;
Yao, Shao Q.

Publication type:

Article

Mitochondria‐Targeted Gene Silencing Facilitated by Mito‐CPDs.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 26, p. 1, doi. 10.1002/chem.202204021

By:

Lang, Wenjie;
Tan, Wei;
Zhou, Bizhong;
Zhuang, Yuli;
Zhang, Bei;
Jiang, Linye;
Yao, Shao Q.;
Ge, Jingyan

Publication type:

Article

Engineered Cell‐Penetrating Peptides for Mitochondrion‐Targeted Drug Delivery in Cancer Therapy.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 59, p. 14721, doi. 10.1002/chem.202102523

By:

Xiao, Qicai;
Dong, Xiao;
Yang, Fen;
Zhou, Shizhe;
Xiang, Menghua;
Lou, Liang;
Yao, Shao Q.;
Gao, Liqian

Publication type:

Article

Cell‐Penetrating Mitochondrion‐Targeting Ligands for the Universal Delivery of Small Molecules, Proteins and Nanomaterials.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 47, p. 12207, doi. 10.1002/chem.202101989

By:

Xiao, Qicai;
Du, Wei;
Dong, Xiao;
Du, Shubo;
Ong, Sing Yee;
Tang, Guanghui;
Zhang, Changyu;
Yang, Fen;
Li, Lin;
Gao, Liqian;
Yao, Shao Q.

Publication type:

Article

Late‐Stage C(sp<sup>2</sup>)−H Functionalization: A Powerful Toolkit To Arm Natural Products for In Situ Proteome Profiling?

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 11, p. 3575, doi. 10.1002/chem.202004373

By:

Lim, Ying‐Jie;
Kuang, Yulong;
Wu, Jie;
Yao, Shao Q.

Publication type:

Article

Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.

Published in:

Angewandte Chemie, 2024, v. 136, n. 12, p. 1, doi. 10.1002/ange.202316394

By:

Tang, Guanghui;
Wang, Wei;
Zhu, Chengjun;
Huang, Huisi;
Chen, Peng;
Wang, Xuan;
Xu, Manyi;
Sun, Jie;
Zhang, Chong‐Jing;
Xiao, Qicai;
Gao, Liqian;
Zhang, Zhi‐Min;
Yao, Shao Q.

Publication type:

Article

Multiplex Identification of Post‐Translational Modifications at Point‐of‐Care by Deep Learning‐Assisted Hydrogel Sensors.

Published in:

Angewandte Chemie, 2023, v. 135, n. 16, p. 1, doi. 10.1002/ange.202218412

By:

Qin, Junjie;
Guo, Jia;
Tang, Guanghui;
Li, Lin;
Yao, Shao Q.

Publication type:

Article

Cell‐Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR‐ABL Kinase.

Published in:

Angewandte Chemie, 2022, v. 134, n. 26, p. 1, doi. 10.1002/ange.202203878

By:

Chen, Peng;
Sun, Jie;
Zhu, Chengjun;
Tang, Guanghui;
Wang, Wei;
Xu, Manyi;
Xiang, Menghua;
Zhang, Chong‐Jing;
Zhang, Zhi‐Min;
Gao, Liqian;
Yao, Shao Q.

Publication type:

Article

Chemical Biology Tools for Protein Lysine Acylation.

Published in:

Angewandte Chemie, 2022, v. 134, n. 21, p. 1, doi. 10.1002/ange.202200303

By:

Xie, Yusheng;
Du, Shubo;
Liu, Zhiyang;
Liu, Min;
Xu, Zhiqiang;
Wang, Xiaojie;
Kee, Jia Xuan;
Yi, Fan;
Sun, Hongyan;
Yao, Shao Q.

Publication type:

Article

Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging.

Published in:

Angewandte Chemie, 2021, v. 133, n. 33, p. 17941, doi. 10.1002/ange.202101964

By:

Ong, Sing Yee;
Zhang, Changyu;
Dong, Xiao;
Yao, Shao Q.

Publication type:

Article

Strategic Design of Catalytic Lysine‐Targeting Reversible Covalent BCR‐ABL Inhibitors.

Published in:

Angewandte Chemie, 2021, v. 133, n. 31, p. 17268, doi. 10.1002/ange.202105383

By:

Quach, David;
Tang, Guanghui;
Anantharajan, Jothi;
Baburajendran, Nithya;
Poulsen, Anders;
Wee, John L. K.;
Retna, Priya;
Li, Rong;
Liu, Boping;
Tee, Doris H. Y.;
Kwek, Perlyn Z.;
Joy, Joma K.;
Yang, Wan‐Qi;
Zhang, Chong‐Jing;
Foo, Klement;
Keller, Thomas H.;
Yao, Shao Q.

Publication type:

Article

Intelligentes Design von Nanomaterialien für Mitochondrien‐gerichtete Nanotherapeutika.

Published in:

Angewandte Chemie, 2021, v. 133, n. 5, p. 2260, doi. 10.1002/ange.201915826

By:

Liew, Si Si;
Qin, Xiaofei;
Zhou, Jia;
Li, Lin;
Huang, Wei;
Yao, Shao Q.

Publication type:

Article

Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues.

Published in:

Angewandte Chemie, 2020, v. 132, n. 19, p. 7606, doi. 10.1002/ange.202000059

By:

Fang, Haixiao;
Zhang, Hang;
Li, Lin;
Ni, Yun;
Shi, Riri;
Li, Zheng;
Yang, Xuekang;
Ma, Bo;
Zhang, Chengwu;
Wu, Qiong;
Yu, Changmin;
Yang, Naidi;
Yao, Shao Q.;
Huang, Wei

Publication type:

Article

Mitochondria‐Targeting, Intracellular Delivery of Native Proteins Using Biodegradable Silica Nanoparticles.

Published in:

Angewandte Chemie, 2019, v. 131, n. 23, p. 7739, doi. 10.1002/ange.201901699

By:

Yuan, Peiyan;
Mao, Xin;
Wu, Xiaofeng;
Liew, Si Si;
Li, Lin;
Yao, Shao Q.

Publication type:

Article

Nanoquencher‐Based Selective Imaging of Protein Glutathionylation in Live Mammalian Cells.

Published in:

Angewandte Chemie, 2018, v. 130, n. 32, p. 10414, doi. 10.1002/ange.201806710

By:

Mao, Xin;
Yuan, Peiyan;
Yu, Changmin;
Li, Lin;
Yao, Shao Q.

Publication type:

Article

Simultaneous Imaging of Endogenous Survivin mRNA and On-Demand Drug Release in Live Cells by Using a Mesoporous Silica Nanoquencher.

Published in:

Small, 2017, v. 13, n. 27, p. n/a, doi. 10.1002/smll.201700569

By:

Yuan, Peiyan;
Mao, Xin;
Chong, Kok Chan;
Fu, Jiaqi;
Pan, Sijun;
Wu, Shuizhu;
Yu, Changmin;
Yao, Shao Q.

Publication type:

Article

A Switchable Two-Photon Membrane Tracer Capable of Imaging Membrane-Associated Protein Tyrosine Phosphatase Activities.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 1, p. 424, doi. 10.1002/anie.201205940

By:

Li, Lin;
Shen, Xiaoqin;
Xu, Qing‐Hua;
Yao, Shao Q.

Publication type:

Article

Dynamic Monitoring of Newly Synthesized Proteomes: Up-Regulation of Myristoylated Protein Kinase A During Butyric Acid Induced Apoptosis.

Published in:

Angewandte Chemie International Edition, 2011, v. 50, n. 30, p. 6776, doi. 10.1002/anie.201102542

By:

Liu, Kai;
Yang, Peng-Yu;
Na, Zhenkun;
Yao, Shao Q.

Publication type:

Article

Microarray-Assisted High-Throughput Identification of a Cell-Permeable Small-Molecule Binder of 14 -3 -3 Proteins.

Published in:

Angewandte Chemie International Edition, 2010, v. 49, n. 37, p. 6528, doi. 10.1002/anie.201003257

By:

Wu, Hao;
Ge, Jingyan;
Yao, Shao Q.

Publication type:

Article

Functional Profiling, Identification, and Inhibition of Plasmepsins in Intraerythrocytic Malaria Parasites.

Published in:

Angewandte Chemie International Edition, 2009, v. 48, n. 44, p. 8293, doi. 10.1002/anie.200903747

By:

Liu, Kai;
Shi, Haibin;
Xiao, Huogen;
Chong, Alvin G. L.;
Bi, Xuezhi;
Chang, Young-Tae;
Tan, Kevin S. W.;
Yada, Rickey Y.;
Yao, Shao Q.

Publication type:

Article

Rapid Affinity-Based Fingerprinting of 14-3-3 Isoforms Using a Combinatorial Peptide Microarray.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 39, p. 7438, doi. 10.1002/anie.200801395

By:

Lu, Candy H. S.;
Sun, Hongyan;
Abu Bakar, Farhana B.;
Uttamchandani, Mahesh;
Zhou, Wei;
Liou, Yih-Cherng;
Yao, Shao Q.

Publication type:

Article

Peptide Microarray for High-Throughput Determination of Phosphatase Specificity and Biology.

Published in:

Angewandte Chemie International Edition, 2008, v. 47, n. 9, p. 1698, doi. 10.1002/anie.200703473

By:

Sun, Hongyan;
Lu, Candy H. S.;
Uttamchandani, Mahesh;
Xia, Yun;
Liou, Yih-Cherng;
Yao, Shao Q.

Publication type:

Article

Kinase Inhibition via Small Molecule‐Induced Intramolecular Protein Cross‐Linking.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 28, p. 1, doi. 10.1002/anie.202404195

By:

Wang, Xuan;
Sun, Jie;
Huang, Huisi;
Tang, Guanghui;
Chen, Peng;
Xiang, Menghua;
Li, Lin;
Zhang, Zhi‐Min;
Gao, Liqian;
Yao, Shao Q.

Publication type:

Article

Targeted Degradation of Cell‐Surface Proteins via Chaperone‐Mediated Autophagy by Using Peptide‐Conjugated Antibodies.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 18, p. 1, doi. 10.1002/anie.202319232

By:

Shao, Jinning;
Lin, Xuefen;
Wang, Haoting;
Zhao, Chuhan;
Yao, Shao Q.;
Ge, Jingyan;
Zeng, Su;
Qian, Linghui

Publication type:

Article

Global Reactivity Profiling of the Catalytic Lysine in Human Kinome for Covalent Inhibitor Development.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 12, p. 1, doi. 10.1002/anie.202316394

By:

Tang, Guanghui;
Wang, Wei;
Zhu, Chengjun;
Huang, Huisi;
Chen, Peng;
Wang, Xuan;
Xu, Manyi;
Sun, Jie;
Zhang, Chong‐Jing;
Xiao, Qicai;
Gao, Liqian;
Zhang, Zhi‐Min;
Yao, Shao Q.

Publication type:

Article

Multiplex Identification of Post‐Translational Modifications at Point‐of‐Care by Deep Learning‐Assisted Hydrogel Sensors.

Published in:

Angewandte Chemie International Edition, 2023, v. 62, n. 16, p. 1, doi. 10.1002/anie.202218412

By:

Qin, Junjie;
Guo, Jia;
Tang, Guanghui;
Li, Lin;
Yao, Shao Q.

Publication type:

Article

Cell‐Active, Reversible, and Irreversible Covalent Inhibitors That Selectively Target the Catalytic Lysine of BCR‐ABL Kinase.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 26, p. 1, doi. 10.1002/anie.202203878

By:

Chen, Peng;
Sun, Jie;
Zhu, Chengjun;
Tang, Guanghui;
Wang, Wei;
Xu, Manyi;
Xiang, Menghua;
Zhang, Chong‐Jing;
Zhang, Zhi‐Min;
Gao, Liqian;
Yao, Shao Q.

Publication type:

Article

Chemical Biology Tools for Protein Lysine Acylation.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 21, p. 1, doi. 10.1002/anie.202200303

By:

Xie, Yusheng;
Du, Shubo;
Liu, Zhiyang;
Liu, Min;
Xu, Zhiqiang;
Wang, Xiaojie;
Kee, Jia Xuan;
Yi, Fan;
Sun, Hongyan;
Yao, Shao Q.

Publication type:

Article

Recent Advances in Polymeric Nanoparticles for Enhanced Fluorescence and Photoacoustic Imaging.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 33, p. 17797, doi. 10.1002/anie.202101964

By:

Ong, Sing Yee;
Zhang, Changyu;
Dong, Xiao;
Yao, Shao Q.

Publication type:

Article

Strategic Design of Catalytic Lysine‐Targeting Reversible Covalent BCR‐ABL Inhibitors**.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 31, p. 17131, doi. 10.1002/anie.202105383

By:

Quach, David;
Tang, Guanghui;
Anantharajan, Jothi;
Baburajendran, Nithya;
Poulsen, Anders;
Wee, John L. K.;
Retna, Priya;
Li, Rong;
Liu, Boping;
Tee, Doris H. Y.;
Kwek, Perlyn Z.;
Joy, Joma K.;
Yang, Wan‐Qi;
Zhang, Chong‐Jing;
Foo, Klement;
Keller, Thomas H.;
Yao, Shao Q.

Publication type:

Article

Smart Design of Nanomaterials for Mitochondria‐Targeted Nanotherapeutics.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 5, p. 2232, doi. 10.1002/anie.201915826

By:

Liew, Si Si;
Qin, Xiaofei;
Zhou, Jia;
Li, Lin;
Huang, Wei;
Yao, Shao Q.

Publication type:

Article

Rational Design of a Two‐Photon Fluorogenic Probe for Visualizing Monoamine Oxidase A Activity in Human Glioma Tissues.

Published in:

Angewandte Chemie International Edition, 2020, v. 59, n. 19, p. 7536, doi. 10.1002/anie.202000059

By:

Fang, Haixiao;
Zhang, Hang;
Li, Lin;
Ni, Yun;
Shi, Riri;
Li, Zheng;
Yang, Xuekang;
Ma, Bo;
Zhang, Chengwu;
Wu, Qiong;
Yu, Changmin;
Yang, Naidi;
Yao, Shao Q.;
Huang, Wei

Publication type:

Article

Mitochondria‐Targeting, Intracellular Delivery of Native Proteins Using Biodegradable Silica Nanoparticles.

Published in:

Angewandte Chemie International Edition, 2019, v. 58, n. 23, p. 7657, doi. 10.1002/anie.201901699

By:

Yuan, Peiyan;
Mao, Xin;
Wu, Xiaofeng;
Liew, Si Si;
Li, Lin;
Yao, Shao Q.

Publication type:

Article

Recent developments in microarray-based enzyme assays: from functional annotation to substrate/inhibitor fingerprinting.

Published in:

Analytical & Bioanalytical Chemistry, 2006, v. 386, n. 3, p. 416, doi. 10.1007/s00216-006-0511-5

By:

Hongyan Sun;
Chattopadhaya, Souvik;
Wang, Jun;
Yao, Shao Q.

Publication type:

Article

Cell‐Active, Arginine‐Targeting Irreversible Covalent Inhibitors for Non‐Kinases and Kinases.

Published in:

Angewandte Chemie, 2025, v. 137, n. 13, p. 1, doi. 10.1002/ange.202422372

By:

Chen, Peng;
Wang, Lu;
Wang, Xuan;
Sun, Jie;
Miao, Fengfei;
Wang, Zuqin;
Yang, Fang;
Xiang, Menghua;
Gu, Mingxi;
Li, Shengrong;
Zhang, Jianzhong;
Yuan, Peiyan;
Lu, Xiaoyun;
Zhang, Zhi‐Min;
Gao, Liqian;
Yao, Shao Q.

Publication type:

Article

Kinase Inhibition via Small Molecule‐Induced Intramolecular Protein Cross‐Linking.

Published in:

Angewandte Chemie, 2024, v. 136, n. 28, p. 1, doi. 10.1002/ange.202404195

By:

Wang, Xuan;
Sun, Jie;
Huang, Huisi;
Tang, Guanghui;
Chen, Peng;
Xiang, Menghua;
Li, Lin;
Zhang, Zhi‐Min;
Gao, Liqian;
Yao, Shao Q.

Publication type:

Article

Targeted Degradation of Cell‐Surface Proteins via Chaperone‐Mediated Autophagy by Using Peptide‐Conjugated Antibodies.

Published in:

Angewandte Chemie, 2024, v. 136, n. 18, p. 1, doi. 10.1002/ange.202319232

By:

Shao, Jinning;
Lin, Xuefen;
Wang, Haoting;
Zhao, Chuhan;
Yao, Shao Q.;
Ge, Jingyan;
Zeng, Su;
Qian, Linghui

Publication type:

Article

Prodrug-conjugated tumor-seeking commensals for targeted cancer therapy.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-48661-y

By:

Shen, Haosheng;
Zhang, Changyu;
Li, Shengjie;
Liang, Yuanmei;
Lee, Li Ting;
Aggarwal, Nikhil;
Wun, Kwok Soon;
Liu, Jing;
Nadarajan, Saravanan Prabhu;
Weng, Cheng;
Ling, Hua;
Tay, Joshua K.;
Wang, De Yun;
Yao, Shao Q.;
Hwang, In Young;
Lee, Yung Seng;
Chang, Matthew Wook

Publication type:

Article

AMPK mediates a pro-survival autophagy downstream of PARP-1 activation in response to DNA alkylating agents

Published in:

FEBS Letters, 2013, v. 587, n. 2, p. 170, doi. 10.1016/j.febslet.2012.11.018

By:

Zhou, Jing;
Ng, Shukie;
Huang, Qing;
Wu, You-Tong;
Li, Zhengqiu;
Yao, Shao Q.;
Shen, Han-Ming

Publication type:

Article

Fused Bicyclic Caspase-1 Inhibitors Assembled by Copper-Free Strain-Promoted Alkyne-Azide Cycloaddition (SPAAC).

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 2, p. 360, doi. 10.1002/chem.201603150

By:

Qian, Linghui;
Zhang, Chong ‐ Jing;
Wu, Ji'en;
Yao, Shao Q.

Publication type:

Article

An Improved Mechanism-Based Cross-Linker for Multiplexed Kinase Detection and Inhibition in a Complex Proteome.

Published in:

ChemBioChem, 2008, v. 9, n. 12, p. 1883, doi. 10.1002/cbic.200800212

By:

Liu, Kai;
Kalesh, Karunakaran A.;
Bing Ong, Li;
Yao, Shao Q.

Publication type:

Article

Activity-Based Protein Profiling: New Developments and Directions in Functional Proteomics.

Published in:

ChemBioChem, 2008, v. 9, n. 5, p. 667, doi. 10.1002/cbic.200700755

By:

Uttamchandani, Mahesh;
Li, Junqi;
Sun, Hongyan;
Yao, Shao Q.

Publication type:

Article