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MAPK phosphatase-3 promotes hepatic gluconeogenesis through dephosphorylation of forkhead box O1 in mice.
- Published in:
- 2010
- By:
- Publication type:
- journal article
Structure‐Guided Discovery of a Potent and Selective Cell‐Active Inhibitor of SETDB1 Tudor Domain.
- Published in:
- Angewandte Chemie, 2021, v. 133, n. 16, p. 8842, doi. 10.1002/ange.202017200
- By:
- Publication type:
- Article
SKLB060 Reversibly Binds to Colchicine Site of Tubulin and Possesses Efficacy in Multidrug-Resistant Cell Lines.
- Published in:
- Cellular Physiology & Biochemistry (Karger AG), 2018, v. 47, n. 2, p. 489, doi. 10.1159/000489983
- By:
- Publication type:
- Article
Non-classical ferroptosis inhibition by a small molecule targeting PHB2.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-35294-2
- By:
- Publication type:
- Article
Generative deep learning enables the discovery of a potent and selective RIPK1 inhibitor.
- Published in:
- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34692-w
- By:
- Publication type:
- Article
Crystal structure of SARS-CoV-2 nsp10/nsp16 2′-O-methylase and its implication on antiviral drug design.
- Published in:
- 2020
- By:
- Publication type:
- Letter
Multispecific drugs: the fourth wave of biopharmaceutical innovation.
- Published in:
- Signal Transduction & Targeted Therapy, 2020, v. 5, n. 1, p. 1, doi. 10.1038/s41392-020-0201-3
- By:
- Publication type:
- Article
Targeting epigenetic regulators for cancer therapy: mechanisms and advances in clinical trials.
- Published in:
- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. 1, doi. 10.1038/s41392-019-0095-0
- By:
- Publication type:
- Article
Jumonji domain-containing 6 (JMJD6) identified as a potential therapeutic target in ovarian cancer.
- Published in:
- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0055-8
- By:
- Publication type:
- Article
Deciphering the regulatory and catalytic mechanisms of an unusual SAM-dependent enzyme.
- Published in:
- Signal Transduction & Targeted Therapy, 2019, v. 4, n. 1, p. N.PAG, doi. 10.1038/s41392-019-0052-y
- By:
- Publication type:
- Article
Correlation between biological activity and binding energy in systems of integrin with cyclic RGD-containing binders: a QM/MM molecular dynamics study.
- Published in:
- Journal of Molecular Modeling, 2012, v. 18, n. 11, p. 4917, doi. 10.1007/s00894-012-1487-z
- By:
- Publication type:
- Article
Information Disclosure of Network Platform and Corporate Social Responsibility Based on Cloud Computing.
- Published in:
- Mobile Information Systems, 2022, p. 1, doi. 10.1155/2022/7501906
- By:
- Publication type:
- Article
Punitive and Rehabilitative Orientations Toward Offenders Among Community Correctional Officers in China.
- Published in:
- Prison Journal, 2016, v. 96, n. 6, p. 771, doi. 10.1177/0032885516671867
- By:
- Publication type:
- Article
Community Corrections in China: Development and Challenges.
- Published in:
- Prison Journal, 2014, v. 94, n. 1, p. 75, doi. 10.1177/0032885513512091
- By:
- Publication type:
- Article
Synergistic antitumor effect of 5-fluorouracil with the novel LSD1 inhibitor ZY0511 in colorectal cancer.
- Published in:
- Therapeutic Advances in Medical Oncology, 2020, v. 12, p. 1, doi. 10.1177/1758835920937428
- By:
- Publication type:
- Article
Inducible overexpression of RUNX1b/c in human embryonic stem cells blocks early hematopoiesis from mesoderm.
- Published in:
- Journal of Molecular Cell Biology, 2017, v. 9, n. 4, p. 262, doi. 10.1093/jmcb/mjx032
- By:
- Publication type:
- Article
Pharmacokinetic Studies of a Novel Multikinase Inhibitor for Treating Cancer by HPLC–UV.
- Published in:
- Journal of Chromatographic Science, 2013, v. 51, n. 1, p. 17, doi. 10.1093/chromsci/bms098
- By:
- Publication type:
- Article
Capsule Networks Showed Excellent Performance in the Classification of hERG Blockers/Nonblockers.
- Published in:
- Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2019.01631
- By:
- Publication type:
- Article
Inhibition of METTL3 Alleviates NLRP3 Inflammasome Activation via Increasing Ubiquitination of NEK7.
- Published in:
- Advanced Science, 2024, v. 11, n. 26, p. 1, doi. 10.1002/advs.202308786
- By:
- Publication type:
- Article
A New Type of Endometrial Cancer Models in Mice Revealing the Functional Roles of Genetic Drivers and Exploring their Susceptibilities.
- Published in:
- Advanced Science, 2023, v. 10, n. 24, p. 1, doi. 10.1002/advs.202300383
- By:
- Publication type:
- Article
Jumonji domain‐containing protein 6 protein and its role in cancer.
- Published in:
- Cell Proliferation, 2020, v. 53, n. 2, p. 1, doi. 10.1111/cpr.12747
- By:
- Publication type:
- Article
Cationic nanocarriers induce cell necrosis through impairment of Na<sup>+</sup>/K<sup>+</sup>-ATPase and cause subsequent inflammatory response.
- Published in:
- Cell Research, 2015, v. 25, n. 2, p. 237, doi. 10.1038/cr.2015.9
- By:
- Publication type:
- Article
Role of Water in the Reaction Mechanism and endo/exo Selectivity of 1,3‐Dipolar Cycloadditions Elucidated by Quantum Chemistry and Machine Learning.
- Published in:
- Chemistry - A European Journal, 2019, v. 25, n. 35, p. 8289, doi. 10.1002/chem.201900617
- By:
- Publication type:
- Article
ZnS/graphene hybrid nanomaterials: synthesis, characterization, and enhanced electrochemical performances.
- Published in:
- Journal of Materials Science: Materials in Electronics, 2015, v. 26, n. 9, p. 6495, doi. 10.1007/s10854-015-3241-7
- By:
- Publication type:
- Article
Individualized network-based drug repositioning infrastructure for precision oncology in the panomics era.
- Published in:
- Briefings in Bioinformatics, 2017, v. 18, n. 4, p. 682, doi. 10.1093/bib/bbw051
- By:
- Publication type:
- Article
Structure‐Guided Discovery of a Potent and Selective Cell‐Active Inhibitor of SETDB1 Tudor Domain.
- Published in:
- Angewandte Chemie International Edition, 2021, v. 60, n. 16, p. 8760, doi. 10.1002/anie.202017200
- By:
- Publication type:
- Article
KIAA0753 enhances osteoblast differentiation suppressed by diabetes.
- Published in:
- Journal of Cellular & Molecular Medicine, 2024, v. 28, n. 17, p. 1, doi. 10.1111/jcmm.70035
- By:
- Publication type:
- Article
SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling.
- Published in:
- British Journal of Cancer, 2017, v. 117, n. 8, p. 1154, doi. 10.1038/bjc.2017.298
- By:
- Publication type:
- Article
SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling.
- Published in:
- 2017
- By:
- Publication type:
- journal article
Recent advances in small-molecular therapeutics for COVID-19.
- Published in:
- Precision Clinical Medicine, 2022, v. 5, n. 4, p. 1, doi. 10.1093/pcmedi/pbac024
- By:
- Publication type:
- Article
Cul4 E3 ubiquitin ligase regulates ovarian cancer drug resistance by targeting the antiapoptotic protein BIRC3.
- Published in:
- Cell Death & Disease, 2019, v. 10, n. 2, p. 1, doi. 10.1038/s41419-018-1200-y
- By:
- Publication type:
- Article
Enhancement of Histone Deacetylase Inhibitor Sensitivity in Combination with Cyclin-Dependent Kinase Inhibition for the Treatment of Oral Squamous Cell Carcinoma.
- Published in:
- Cellular Physiology & Biochemistry (Cell Physiol Biochem Press GmbH & Co. KG), 2019, v. 53, n. 1, p. 141, doi. 10.33594/000000126
- By:
- Publication type:
- Article
Icariin Treatment Rescues Diabetes Induced Bone Loss via Scavenging ROS and Activating Primary Cilia/Gli2/Osteocalcin Signaling Pathway.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 24, p. 4091, doi. 10.3390/cells11244091
- By:
- Publication type:
- Article
Dihydroartemisinin Inhibits mTORC1 Signaling by Activating the AMPK Pathway in Rhabdomyosarcoma Tumor Cells.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 6, p. 1363, doi. 10.3390/cells10061363
- By:
- Publication type:
- Article
YL529, a novel, orally available multikinase inhibitor, potently inhibits angiogenesis and tumour growth in preclinical models.
- Published in:
- 2013
- By:
- Publication type:
- journal article
YL529, a novel, orally available multikinase inhibitor, potently inhibits angiogenesis and tumour growth in preclinical models.
- Published in:
- British Journal of Pharmacology, 2013, v. 169, n. 8, p. 1766, doi. 10.1111/bph.12216
- By:
- Publication type:
- Article
Physisorption of cis- and trans-decalin on Pt<sub>4</sub> clusters from density functional theory calculations.
- Published in:
- Physica Status Solidi. A: Applications & Materials Science, 2011, v. 208, n. 10, p. 2380, doi. 10.1002/pssa.201084197
- By:
- Publication type:
- Article
Discovery of 12O—A Novel Oral Multi-Kinase Inhibitor for the Treatment of Solid Tumor.
- Published in:
- Molecules, 2020, v. 25, n. 21, p. 5199, doi. 10.3390/molecules25215199
- By:
- Publication type:
- Article
A small molecular agent YL529 inhibits VEGF-D-induced lymphangiogenesis and metastasis in preclinical tumor models in addition to its known antitumor activities.
- Published in:
- BMC Cancer, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12885-015-1451-2
- By:
- Publication type:
- Article
A small molecular agent YL529 inhibits VEGF-D-induced lymphangiogenesis and metastasis in preclinical tumor models in addition to its known antitumor activities
- Published in:
- BMC Cancer, 2015, v. 15, n. 1, p. 525, doi. 10.1186/s12885-015-1451-2
- By:
- Publication type:
- Article
Preclinical pharmacodynamic evaluation of a new Src/FOSL1 inhibitor, LY‐1816, in pancreatic ductal adenocarcinoma.
- Published in:
- Cancer Science, 2019, v. 110, n. 4, p. 1408, doi. 10.1111/cas.13929
- By:
- Publication type:
- Article
Small molecules in targeted cancer therapy: advances, challenges, and future perspectives.
- Published in:
- Signal Transduction & Targeted Therapy, 2021, v. 6, n. 1, p. 1, doi. 10.1038/s41392-021-00572-w
- By:
- Publication type:
- Article
Antimicrobial peptide DP7 with potential activity against SARS coronavirus infections.
- Published in:
- 2021
- By:
- Publication type:
- Letter
The novel LSD1 inhibitor ZY0511 suppresses diffuse large B-cell lymphoma proliferation by inducing apoptosis and autophagy.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode.
- Published in:
- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-19109-w
- By:
- Publication type:
- Article
Lipidomic profiling reveals lipid regulation by a novel LSD1 inhibitor treatment.
- Published in:
- Oncology Reports, 2021, v. 46, n. 5, p. N.PAG, doi. 10.3892/or.2021.8184
- By:
- Publication type:
- Article
Arginine Methyltransferase 1 in the Nucleus Accumbens Regulates Behavioral Effects of Cocaine.
- Published in:
- Journal of Neuroscience, 2015, v. 35, n. 37, p. 12890, doi. 10.1523/JNEUROSCI.0246-15.2015
- By:
- Publication type:
- Article