Works by Yan, Riqiang

Results: 54

ER‐stress response in retinal Müller glia occurs significantly earlier than amyloid pathology in the Alzheimer's mouse brain and retina.

Published in:

Glia (0894-1491), 2024, v. 72, n. 6, p. 1067, doi. 10.1002/glia.24514

By:

Palko, Sarah I.;
Benoit, Marc R.;
Yao, Annie Y.;
Mohan, Royce;
Yan, Riqiang

Publication type:

Article

The sterol regulatory element‐binding protein 2 is dysregulated by tau alterations in Alzheimer disease.

Published in:

Brain Pathology, 2019, v. 29, n. 4, p. 530, doi. 10.1111/bpa.12691

By:

Wang, Chunyu;
Zhao, Fanpeng;
Shen, Katie;
Wang, Wenzhang;
Siedlak, Sandra L.;
Lee, Hyoung‐gon;
Phelix, Clyde F.;
Perry, George;
Shen, Lu;
Tang, Beisha;
Yan, Riqiang;
Zhu, Xiongwei

Publication type:

Article

Reticulon family members modulate BACE1 activity and amyloid-ßpeptide generation.

Published in:

Nature Medicine, 2004, v. 10, n. 9, p. 959, doi. 10.1038/nm1088

By:

Wanxia He;
Yifeng Lu;
Qahwash, Isam;
Xiang-You Hu;
Ansi Chang;
Riqiang Yan

Publication type:

Article

Elevated β-secretase expression and enzymatic activity detected in sporadic Alzheimer disease.

Published in:

Nature Medicine, 2003, v. 9, n. 1, p. 3, doi. 10.1038/nm0103-3

By:

Yang, Li-Bang;
Lindholm, Kristina;
Yan, Riqiang;
Citron, Martin;
Xia, Weiming;
Yang, Xiao-Li;
Beach, Thomas;
Sue, Lucia;
Wong, Philip;
Price, Donald;
Li, Rena;
Shen, Yong

Publication type:

Article

NOGO is increased and binds to BACE1 in sporadic inclusion-body myositis and in AβPP-overexpressing cultured human muscle fibers.

Published in:

Acta Neuropathologica, 2007, v. 114, n. 5, p. 517, doi. 10.1007/s00401-007-0281-y

By:

Wojcik, Slawomir;
Engel, W. King;
Riqiang Yan;
McFerrin, Janis;
Askanas, Valerie

Publication type:

Article

VPS35 haploinsufficiency increases Alzheimer's disease neuropathology.

Published in:

Journal of Cell Biology, 2011, v. 195, n. 5, p. 765, doi. 10.1083/jcb.201105109

By:

Lei Wen;
Fu-Lei Tang;
Yan Hong;
Shi-Wen Luo;
Chun-Lei Wang;
Wanxia He;
Chengyong Shen;
Ji-Ung Jung;
Fei Xiong;
Dae-hoon Lee;
Quan-Guang Zhang;
Darrell Brann;
Tae-Wan Kim;
Riqiang Yan;
Lin Mei;
Wen-Cheng Xiong

Publication type:

Article

A Close Look at BACE1 Inhibitors for Alzheimer's Disease Treatment.

Published in:

2019

By:

Das, Brati;
Yan, Riqiang

Publication type:

journal article

Reversing hypomyelination in BACE1-null mice with Akt-DD overexpression.

Published in:

FASEB Journal, 2013, v. 27, n. 5, p. 1868, doi. 10.1096/fj.12-224212

By:

Xiangyou Hu;
Schlanger, Rita;
Wanxia He;
Macklin, Wendy B.;
Riqiang Yan

Publication type:

Article

Interaction between amyloid precursor protein and Nogo receptors regulates amyloid deposition.

Published in:

FASEB Journal, 2011, v. 25, n. 9, p. 3146, doi. 10.1096/fj.11-184325

By:

Xiangdong Zhou;
Xiangyou Hu;
Wanxia He;
Xiaoying Tang;
Qi Shi;
Zhuohua Zhang;
Riqiang Yan

Publication type:

Article

Genetic deletion of BACE1 in mice affects remyelination of sciatic nerves.

Published in:

FASEB Journal, 2008, v. 22, n. 8, p. 2970, doi. 10.1096/fj.08-106666

By:

Xiangyou Hu;
Wanxia He;
Diaconu, Claudiu;
Xiaoying Tang;
Kidd, Grahame J.;
Macklin, Wendy B.;
Trapp, Bruce D.;
Riqiang Yan

Publication type:

Article

Widespread distribution of reticulon-3 in various neurodegenerative diseases.

Published in:

Neuropathology, 2010, v. 30, n. 6, p. 574, doi. 10.1111/j.1440-1789.2010.01107.x

By:

Heath, Jonathon E.;
Siedlak, Sandra L.;
Zhu, Xiongwei;
Lee, Hyoung-gon;
Thakur, Akanksha;
Yan, Riqiang;
Perry, George;
Smith, Mark A.;
Castellani, Rudy J.

Publication type:

Article

Reticulons 1 and 3 are essential for axonal growth and synaptic maintenance associated with intellectual development.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 16, p. 2587, doi. 10.1093/hmg/ddad085

By:

Zhou, John;
Shi, Qi;
Ge, Ying Y;
He, Wanxia;
Hu, Xiangyou;
Xia, Weiming;
Yan, Riqiang

Publication type:

Article

Postnatal neuronal Bace1 deletion impairs neuroblast and oligodendrocyte maturation.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 7, p. 1193, doi. 10.1093/hmg/ddac282

By:

Benoit, Marc R;
Darboe, Mabintou;
Das, Brati;
Ge, Yingying;
Zhou, John;
Yao, Annie;
He, Wanxia;
Yan, Riqiang;
Hu, Xiangyou

Publication type:

Article

Exploration of C-terminal CX3CL1 for reducing age-dependent neurodegeneration.

Published in:

Neural Regeneration Research, 2023, v. 18, n. 12, p. 2667, doi. 10.4103/1673-5374.373702

By:

Hudobenko, Jacob;
Gayen, Manoshi;
Benoit, Marc R.;
Singh, Neeraj;
Riqiang Yan

Publication type:

Article

Effects of altered RTN3 expression on BACE1 activity and Alzheimer's neuritic plaques.

Published in:

Reviews in the Neurosciences, 2017, v. 28, n. 2, p. 145, doi. 10.1515/revneuro-2016-0054

By:

Sharoar, Md Golam;
Yan, Riqiang

Publication type:

Article

Axonal and Schwann Cell BACE1 Is Equally Required for Remyelination of Peripheral Nerves.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 9, p. 3806, doi. 10.1523/JNEUROSCI.5207-14.2015

By:

Xiangyou Hu;
Jinxuan Hu;
Lu Dai;
Trap, Bruce;
Riqiang Yan

Publication type:

Article

Impact of RTN3 Deficiency on Expression of BACE1 and Amyloid Deposition.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 42, p. 13954, doi. 10.1523/JNEUROSCI.1588-14.2014

By:

Qi Shi;
Yingying Ge;
Sharoar, Md. Golam;
He, Wanxia;
Xiang, Rong;
Zhang, Zhuohua;
Hu, Xiangyou;
Yan, Riqiang

Publication type:

Article

Preventing Formation of Reticulon 3 Immunoreactive Dystrophic Neurites Improves Cognitive Function in Mice.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 7, p. 3059, doi. 10.1523/JNEUROSCI.2445-12.2013

By:

Qi Shi;
Marguerite Prior;
Xiangdong Zhou;
Xiaoying Tang;
Wanxia He;
Xiangyou Hu;
Riqiang Yan

Publication type:

Article

Inhibition of BACE1 in glial cells for enhancing clearance of amyloid plaques.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083297

By:

Yan, Riqiang

Publication type:

Article

Deletion of neuronal BACE1 causes mice memory deficits: Molecular and cell biology/APP/Abeta/amyloid.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043965

By:

Hu, Xiangyou;
Darboe, Mabintou;
Yan, Riqiang

Publication type:

Article

A novel interaction between AD risk genes synaptojanin 1 and reticulon‐3 potentially impacts synaptic function and endo‐lysosomal trafficking during disease development and progression: Molecular and cell biology: Endo‐lysosomal/trafficking dysfunction

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043247

By:

Cai, Dongming;
Huang, Min;
Cao, Jiqing;
Hou, Jianwei;
Zhu, Li;
Zhang, Larry;
Pero, Adriana;
Guo, Lei;
T.C.W., Julia;
Zhong, Minghao;
Goate, Alison M.;
Zhang, Bin;
Yan, Riqiang

Publication type:

Article

Dynactin 6 deficiency enhances tubular ER‐associated dystrophic neurites formation: Molecular and cell biology/axonal transport.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043049

By:

Sharoar, Md. Golam;
Yan, Riqiang

Publication type:

Article

P1‐206: THE CONSTITUTION OF DYSTROPHIC NEURITES IN AGING AND IN ALZHEIMER'S DISEASE MOUSE MODEL BRAIN AND THEIR 3D STRUCTURES.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P358, doi. 10.1016/j.jalz.2018.06.211

By:

Sharoar, Md. Golam;
Hu, Xiang-You;
Yan, Riqiang

Publication type:

Article

Bace1 modulates myelination in the central and peripheral nervous system.

Published in:

Nature Neuroscience, 2006, v. 9, n. 12, p. 1520, doi. 10.1038/nn1797

By:

Xiangyou Hu;
Hicks, Caitlin W.;
Wanxia He;
Wong, Philip;
Macklin, Wendy B.;
Trapp, Bruce D.;
Riqiang Yan

Publication type:

Article

Homogeneity of active demyelinating lesions in established multiple sclerosis.

Published in:

Annals of Neurology, 2008, v. 63, n. 1, p. 16, doi. 10.1002/ana.21311

By:

Breij, Esther C. W.;
Brink, Bianca P.;
Veerhuis, Rob;
van den Berg, Christa;
Vloet, Rianka;
Yan, Riqiang;
Dijkstra, Christine D.;
van der Valk, Paul;
Bö, Lars

Publication type:

Article

O1-03-01: Reduced amyloid deposition in mice overexpressing RTN3 is adversely affected by preformed dystrophic neurites

Published in:

2008

By:

Yan, Riqiang;
Shi, Qi;
Hu, Xiangyou;
Prior, Marguerite;
Zhou, Xiangdong;
He, Wanxia

Publication type:

Abstract

Reticulon 3 aggregation and its role in the formation of dystrophic neurites.

Published in:

2012

By:

Riqiang Yan

Publication type:

Abstract

APPswe/Aβ regulation of osteoclast activation and RAGE expression in an age-dependent manner.

Published in:

Journal of Bone & Mineral Research, 2011, v. 26, n. 5, p. 1084, doi. 10.1002/jbmr.299

By:

Shun Cui;
Fei Xiong;
Yan Hong;
Ji-Ung Jung;
Xing-Sheng Li;
Jian-Zhong Liu;
Riqiang Yan;
Lin Mei;
Xu Feng;
Wen-Cheng Xiong

Publication type:

Article

Employing a superior BACE1 cleavage sequence to probe cellular APP processing.

Published in:

Journal of Neurochemistry, 2003, v. 84, n. 5, p. 1006, doi. 10.1046/j.1471-4159.2003.01597.x

By:

Tomasselli, Alfredo G.;
Qahwash, Isam;
Emmons, Thomas L.;
Lu, Yifeng;
Leone, Joseph W.;
Lull, June M.;
Fok, Kam F.;
Bannow, Carol A.;
Smith, Clark W.;
Bienkowski, Michael J.;
Heinrikson, Robert L.;
Yan, Riqiang

Publication type:

Article

Ex vivo propagation of synaptically-evoked cortical depolarizations in a mouse model of Alzheimer's disease at 20 Hz, 40 Hz, or 83 Hz.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-74262-2

By:

Patel, Aayushi A.;
Zhu, Mei Hong;
Yan, Riqiang;
Antic, Srdjan D.

Publication type:

Article

β-Secretase1 biological markers for Alzheimer's disease: state-of-art of validation and qualification.

Published in:

Alzheimer's Research & Therapy, 2020, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13195-020-00686-3

By:

Hampel, Harald;
Lista, Simone;
Vanmechelen, Eugeen;
Zetterberg, Henrik;
Giorgi, Filippo Sean;
Galgani, Alessandro;
Blennow, Kaj;
Caraci, Filippo;
Das, Brati;
Yan, Riqiang;
Vergallo, Andrea;
for the Alzheimer's Precision Medicine Initiative (APMI);
Afshar, Mohammad;
Aguilar, Lisi Flores;
Akman-Anderson, Leyla;
Arenas, Joaquín;
Ávila, Jesús;
Babiloni, Claudio;
Baldacci, Filippo;
Batrla, Richard

Publication type:

Article

Physiological Functions of the β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and 2.

Published in:

Frontiers in Molecular Neuroscience, 2017, p. 1, doi. 10.3389/fnmol.2017.00097

By:

Riqiang Yan

Publication type:

Article

Contribution of amyloid deposition from oligodendrocytes in a mouse model of Alzheimer's disease.

Published in:

Molecular Neurodegeneration, 2024, v. 19, n. 1, p. 1, doi. 10.1186/s13024-024-00759-z

By:

Ishii, Akihiro;
Pathoulas, Joseph A.;
MoustafaFathy Omar, Omar;
Ge, Yingying;
Yao, Annie Y.;
Pantalena, Tressa;
Singh, Neeraj;
Zhou, John;
He, Wanxia;
Murphy, Patrick;
Yan, Riqiang;
Hu, Xiangyou

Publication type:

Article

Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling.

Published in:

Journal of Neurochemistry, 2016, v. 136, n. 2, p. 234, doi. 10.1111/jnc.13395

By:

Hu, Xiangyou;
Fan, Qingyuan;
Hou, Hailong;
Yan, Riqiang

Publication type:

Article

Alzheimer's disease amyloidogenesis is linked to altered lower urinary tract physiology.

Published in:

Neurourology & Urodynamics, 2022, v. 41, n. 6, p. 1344, doi. 10.1002/nau.24952

By:

Hardy, Cara C.;
Ramasamy, Ramalakshmi;
Rosenberg, Dawn A.;
Kuchel, George A.;
Yan, Riqiang;
Hu, Xiangyou;
Smith, Phillip P.

Publication type:

Article

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.

Published in:

Nature, 1999, v. 402, n. 6761, p. 533, doi. 10.1038/990107

By:

Riqiang Yan;
Bienkowski, Michael J.

Publication type:

Article

Role of BACE1 in Alzheimer's synaptic function.

Published in:

Translational Neurodegeneration, 2017, v. 6, n. 1, p. 1, doi. 10.1186/s40035-017-0093-5

By:

Das, Brati;
Riqiang Yan

Publication type:

Article

Stepping closer to treating Alzheimer's disease patients with BACE1 inhibitor drugs.

Published in:

Translational Neurodegeneration, 2016, v. 5, p. 1, doi. 10.1186/s40035-016-0061-5

By:

Riqiang Yan

Publication type:

Article

Bace1 Deletion in the Adult Reverses Epileptiform Activity and Sleep-wake Disturbances in AD Mice.

Published in:

Journal of Neuroscience, 2023, v. 43, n. 35, p. 6197, doi. 10.1523/JNEUROSCI.2124-22.2023

By:

Yao, Annie Y.;
Halloran, Patrick J.;
Yingying Ge;
Singh, Neeraj;
Zhou, John;
Galske, James;
Wanxia He;
Riqiang Yan;
Xiangyou Hu

Publication type:

Article

Activated CX3CL1/Smad2 Signals Prevent Neuronal Loss and Alzheimer's Tau Pathology-Mediated Cognitive Dysfunction.

Published in:

Journal of Neuroscience, 2020, v. 40, n. 5, p. 1133, doi. 10.1523/jneurosci.1333-19.2019

By:

Qingyuan Fan;
Wanxia He;
Manoshi Gayen;
Benoit, Marc Robert;
Xiaoyang Luo;
Xiangyou Hu;
Riqiang Yan

Publication type:

Article

Klotho Regulated by Estrogen Plays a Key Role in Sex Differences in Stress Resilience in Rats.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 2, p. 1206, doi. 10.3390/ijms24021206

By:

Tan, Zhinei;
Li, Yongxia;
Guan, Yinzheng;
Iqbal, Javed;
Wang, Chenyue;
Yan, Riqiang;
Ma, Xin-Ming

Publication type:

Article

Linking APOE4/4 genotype to microglial lipid droplets and neurotoxicity in Alzheimer's disease.

Published in:

Translational Neurodegeneration, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40035-024-00433-w

By:

Huang, Hao;
Xiang, Rong;
Yan, Riqiang

Publication type:

Article

BACE1 regulates expression of Clusterin in astrocytes for enhancing clearance of β-amyloid peptides.

Published in:

Molecular Neurodegeneration, 2023, v. 18, n. 1, p. 1, doi. 10.1186/s13024-023-00611-w

By:

Zhou, John;
Singh, Neeraj;
Galske, James;
Hudobenko, Jacob;
Hu, Xiangyou;
Yan, Riqiang

Publication type:

Article

Accumulation of saposin in dystrophic neurites is linked to impaired lysosomal functions in Alzheimer's disease brains.

Published in:

Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00464-1

By:

Sharoar, Md Golam;
Palko, Sarah;
Ge, Yingying;
Saido, Takaomi C.;
Yan, Riqiang

Publication type:

Article

Activity of Alzheimer's γ-secretase is linked to changes of interferon-induced transmembrane proteins (IFITM) in innate immunity.

Published in:

2020

By:

Yao, Annie Y.;
Yan, Riqiang

Publication type:

Letter

BACE1 regulates the proliferation and cellular functions of Schwann cells.

Published in:

Glia (0894-1491), 2017, v. 65, n. 5, p. 712, doi. 10.1002/glia.23122

By:

Hu, Xiangyou;
Hou, Hailong;
Bastian, Chinthasagar;
He, Wanxia;
Qiu, Shupeng;
Ge, Yingying;
Yin, Xinhua;
Kidd, Grahame J.;
Brunet, Sylvain;
Trapp, Bruce D.;
Baltan, Selva;
Yan, Riqiang

Publication type:

Article

Identification of rare <italic>RTN3</italic> variants in Alzheimer’s disease in Han Chinese.

Published in:

Human Genetics, 2018, v. 137, n. 2, p. 141, doi. 10.1007/s00439-018-1868-1

By:

Zou, Yongyi;
He, Wanxia;
Wang, Kangli;
Han, Hailong;
Xiao, Tingting;
Chen, Xumeng;
Zhou, Bin;
Tan, Jieqiong;
Xia, Kun;
Tang, Beisha;
Chen, Chao;
Shen, Lu;
Yan, Riqiang;
Zhang, Zhuohua

Publication type:

Article

Regulatory role of cathepsin L in induction of nuclear laminopathy in Alzheimer's disease.

Published in:

Aging Cell, 2022, v. 21, n. 1, p. 1, doi. 10.1111/acel.13531

By:

Islam, Md Imamul;
Nagakannan, Pandian;
Shcholok, Tetiana;
Contu, Fabio;
Mai, Sabine;
Albensi, Benedict C;
Del Bigio, Marc R.;
Wang, Jun‐Feng;
Sharoar, Md Golam;
Yan, Riqiang;
Park, Il‐Seon;
Eftekharpour, Eftekhar

Publication type:

Article

Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1.

Published in:

Molecular Neurodegeneration, 2008, v. 3, p. 1, doi. 10.1186/1750-1326-3-6

By:

Carter, Donald B.;
Dunn, Edwige;
Pauley, Adele M.;
McKinley, Denise D.;
Fleck, Timothy J.;
Ellerbrook, Brenda R.;
Stratman, Nancy C.;
Xiangdong Zhou;
Himes, Carol S.;
Nye, Jeffrey S.;
Tomasselli, Alfredo;
Riqiang Yan

Publication type:

Article

BACE1 Deficiency Causes Altered Neuronal Activity and Neurodegeneration.

Published in:

Journal of Neuroscience, 2010, v. 30, n. 26, p. 8819, doi. 10.1523/JNEUROSCI.1334-10.2010

By:

Xiangyou Hu;
Xiangdong Zhou;
Wanxia He;
Jun Yang;
Wencheng Xiong;
Wong, Philip;
Wilson, Christopher G.;
Riqiang Yan

Publication type:

Article