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Tofogliflozin does not delay progression of carotid atherosclerosis in patients with type 2 diabetes: a prospective, randomized, open-label, parallel-group comparative study.
Published in:
Cardiovascular Diabetology, 2020, v. 19, n. 1, p. 1, doi. 10.1186/s12933-020-01079-4
By:
- Katakami, Naoto;
- Mita, Tomoya;
- Yoshii, Hidenori;
- Shiraiwa, Toshihiko;
- Yasuda, Tetsuyuki;
- Okada, Yosuke;
- Torimoto, Keiichi;
- Umayahara, Yutaka;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Yamamoto, Tsunehiko;
- Kuribayashi, Nobuichi;
- Maeda, Kazuhisa;
- Yokoyama, Hiroki;
- Kosugi, Keisuke;
- Ohtoshi, Kentaro;
- Hayashi, Isao;
- Sumitani, Satoru;
- Tsugawa, Mamiko;
- Ryomoto, Kayoko
Publication type:
Article
Tofogliflozin long-term effects on atherosclerosis progression and major clinical parameters in patients with type 2 diabetes mellitus lacking a history of cardiovascular disease: a 2-year extension study of the UTOPIA trial.
Published in:
Cardiovascular Diabetology, 2023, v. 22, n. 1, p. 1, doi. 10.1186/s12933-023-01879-4
By:
- Katakami, Naoto;
- Mita, Tomoya;
- Yoshii, Hidenori;
- Shiraiwa, Toshihiko;
- Yasuda, Tetsuyuki;
- Okada, Yosuke;
- Kurozumi, Akira;
- Hatazaki, Masahiro;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Yamamoto, Tsunehiko;
- Kuribayashi, Nobuichi;
- Maeda, Kazuhisa;
- Yokoyama, Hiroki;
- Kosugi, Keisuke;
- Ohtoshi, Kentaro;
- Hayashi, Isao;
- Sumitani, Satoru;
- Tsugawa, Mamiko;
- Ryomoto, Kayoko
Publication type:
Article
Effect of sodium–glucose cotransporter 2 inhibitors on serum low‐density lipoprotein cholesterol in Japanese patients with type 2 diabetes mellitus.
Published in:
Journal of Diabetes Investigation, 2024, v. 15, n. 7, p. 843, doi. 10.1111/jdi.14179
By:
- Imada, Tasuku;
- Katakami, Naoto;
- Watanabe, Hirotaka;
- Nishina, Shuhei;
- Sasaki, Shugo;
- Takahara, Mitsuyoshi;
- Shimomura, Iichiro;
- Yamamoto, Tsunehiko
Publication type:
Article
High prevalence and clinical impact of dynapenia and sarcopenia in Japanese patients with type 1 and type 2 diabetes: Findings from the Impact of Diabetes Mellitus on Dynapenia study.
Published in:
Journal of Diabetes Investigation, 2021, v. 12, n. 6, p. 1050, doi. 10.1111/jdi.13436
By:
- Mori, Hiroyasu;
- Kuroda, Akio;
- Yoshida, Sumiko;
- Yasuda, Tetsuyuki;
- Umayahara, Yutaka;
- Shimizu, Sayoko;
- Ryomoto, Kayoko;
- Yoshiuchi, Kazutomi;
- Yamamoto, Tsunehiko;
- Matsuoka, Taka‐aki;
- Shimomura, Iichiro;
- Matsuhisa, Munehide
Publication type:
Article
Impact of diabetes on coronary stenosis and coronary artery calcification detected by electron-beam computed tomography in symptomatic patients.
Published in:
2002
By:
- Hosoi, Masayuki;
- Sato, Toshihiko;
- Yamagami, Keiko;
- Hasegawa, Takanori;
- Yamakita, Tetsuya;
- Miyamoto, Masafumi;
- Yoshioka, Katsunobu;
- Yamamoto, Tsunehiko;
- Ishii, Tomofusa;
- Tanaka, Shiro;
- Fujii, Satoru;
- Itoh, Akira;
- Haze, Kazuo
Publication type:
journal article
Associations of continuous glucose monitoring-assessed glucose variability with intima-media thickness and ultrasonic tissue characteristics of the carotid arteries: a cross-sectional analysis in patients with type 2 diabetes.
Published in:
Cardiovascular Diabetology, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12933-021-01288-5
By:
- Taya, Naohiro;
- Katakami, Naoto;
- Mita, Tomoya;
- Okada, Yosuke;
- Wakasugi, Satomi;
- Yoshii, Hidenori;
- Shiraiwa, Toshihiko;
- Otsuka, Akihito;
- Umayahara, Yutaka;
- Ryomoto, Kayoko;
- Hatazaki, Masahiro;
- Yasuda, Tetsuyuki;
- Yamamoto, Tsunehiko;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka
Publication type:
Article
Effect of tofogliflozin on arterial stiffness in patients with type 2 diabetes: prespecified sub-analysis of the prospective, randomized, open-label, parallel-group comparative UTOPIA trial.
Published in:
Cardiovascular Diabetology, 2021, v. 20, n. 1, p. 1, doi. 10.1186/s12933-020-01206-1
By:
- Katakami, Naoto;
- Mita, Tomoya;
- Yoshii, Hidenori;
- Shiraiwa, Toshihiko;
- Yasuda, Tetsuyuki;
- Okada, Yosuke;
- Torimoto, Keiichi;
- Umayahara, Yutaka;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Yamamoto, Tsunehiko;
- Kuribayashi, Nobuichi;
- Maeda, Kazuhisa;
- Yokoyama, Hiroki;
- Kosugi, Keisuke;
- Ohtoshi, Kentaro;
- Hayashi, Isao;
- Sumitani, Satoru;
- Tsugawa, Mamiko;
- Ryomoto, Kayoko
Publication type:
Article
Ptf1a and RBP-J Cooperatively Regulate Pdx1 Gene Expression Through Binding to Conserved Sequences Within Area HI.
Published in:
Diabetes, 2007, v. 56, p. A429
By:
- Miyatsuka, Takeshi;
- Matsuoka, Taka-Aki;
- Yamamoto, Tsunehiko;
- Shiraiwa, Toshihiko;
- Kato, Ken;
- Yamasaki, Yoshimitsu;
- Kaneto, Hideaki
Publication type:
Article
The Influence of Tofogliflozin on Treatment-Related Quality of Life in Patients with Type 2 Diabetes Mellitus.
Published in:
Diabetes Therapy, 2021, v. 12, n. 9, p. 2499, doi. 10.1007/s13300-021-01125-8
By:
- Katakami, Naoto;
- Mita, Tomoya;
- Yoshii, Hidenori;
- Shiraiwa, Toshihiko;
- Yasuda, Tetsuyuki;
- Okada, Yosuke;
- Torimoto, Keiichi;
- Umayahara, Yutaka;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Yamamoto, Tsunehiko;
- Kuribayashi, Nobuichi;
- Maeda, Kazuhisa;
- Yokoyama, Hiroki;
- Kosugi, Keisuke;
- Ohtoshi, Kentaro;
- Hayashi, Isao;
- Sumitani, Satoru;
- Tsugawa, Mamiko;
- Ryomoto, Kayoko
Publication type:
Article
Rationale, Design, and Baseline Characteristics of the Utopia Trial for Preventing Diabetic Atherosclerosis Using an SGLT2 Inhibitor: A Prospective, Randomized, Open-Label, Parallel-Group Comparative Study.
Published in:
Diabetes Therapy, 2017, v. 8, n. 5, p. 999, doi. 10.1007/s13300-017-0292-1
By:
- Naoto Katakami;
- Tomoya Mita;
- Hidenori Yoshii;
- Toshihiko Shiraiwa;
- Tetsuyuki Yasuda;
- Yosuke Okada;
- Yutaka Umayahara;
- Hideaki Kaneto;
- Takeshi Osonoi;
- Tsunehiko Yamamoto;
- Nobuichi Kuribayashi;
- Kazuhisa Maeda;
- Hiroki Yokoyama;
- Keisuke Kosugi;
- Kentaro Ohtoshi;
- Isao Hayashi;
- Satoru Sumitani;
- Mamiko Tsugawa;
- Makoto Ohashi;
- Hideki Taki
Publication type:
Article
Rationale, design, and baseline characteristics of a clinical trial for prevention of atherosclerosis in patients with insulin-treated type 2 diabetes mellitus using DPP-4 inhibitor: the Sitagliptin Preventive study of Intima-media thickness Evaluation (SPIKE)
Published in:
Diabetology & Metabolic Syndrome, 2014, v. 6, n. 1, p. 1, doi. 10.1186/1758-5996-6-35
By:
- Mita, Tomoya;
- Katakami, Naoto;
- Shiraiwa, Toshihiko;
- Yoshii, Hidenori;
- Onuma, Tomio;
- Kuribayashi, Nobuichi;
- Osonoi, Takeshi;
- Kaneto, Hideaki;
- Kosugi, Keisuke;
- Umayahara, Yutaka;
- Yamamoto, Tsunehiko;
- Matsumoto, Kazunari;
- Yokoyama, Hiroki;
- Tsugawa, Mamiko;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka
Publication type:
Article
A case of ectopic ACTH syndrome due to DDAVP-sensitive but V1b receptor-negative bronchial typical carcinoid with lymphatic metastasis and plasma ProGRP elevation.
Published in:
Endocrine Journal, 2018, v. 65, n. 12, p. 1161, doi. 10.1507/endocrj.ej18-0052
By:
- Tadashi Yamamuro;
- Kana Inoue;
- Yasuki Nagai;
- Daisuke Azuma;
- Aya Yamamoto;
- Kantaro Hara;
- Masaharu Kohara;
- Takashi Iwata;
- Shinichi Nakatsuka;
- Eiichi Morii;
- Tsunehiko Yamamoto
Publication type:
Article
Clinical and endocrinological characteristics of adrenal incidentaloma in Osaka region, Japan.
Published in:
Endocrine Journal, 2016, v. 63, n. 1, p. 29, doi. 10.1507/endocrj.ej15-0404
By:
- Yukiko Tabuchi;
- Michio Otsuki;
- Soji Kasayama;
- Keisuke Kosugi;
- Kunihiko Hashimoto;
- Tsunehiko Yamamoto;
- Mamiko Tsugawa;
- Ikuo Mineo;
- Yuya Yamada;
- Shogo Kurebayashi;
- Makoto Ohashi;
- Yutaka Umayahara;
- Haruhiko Kouhara;
- Tadashi Nakamura;
- Hideki Taki;
- Taka-aki Matsuoka;
- Akihisa Imagawa;
- Tohru Funahashi;
- Iichiro Shimomura
Publication type:
Article
Erratum. Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A). Diabetes Care 2016;39:139-148.
Published in:
2017
By:
- Mita, Tomoya;
- Katakami, Naoto;
- Yoshii, Hidenori;
- Onuma, Tomio;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Shiraiwa, Toshihiko;
- Kosugi, Keisuke;
- Umayahara, Yutaka;
- Yamamoto, Tsunehiko;
- Yokoyama, Hiroki;
- Kuribayashi, Nobuichi;
- Jinnouchi, Hideaki;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka;
- Collaborators on the Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A) Trial
Publication type:
journal article
Erratum. Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE). A Randomized Controlled Trial. Diabetes Care 2016;39:455-464.
Published in:
2017
By:
- Mita, Tomoya;
- Katakami, Naoto;
- Shiraiwa, Toshihiko;
- Yoshii, Hidenori;
- Onuma, Tomio;
- Kuribayashi, Nobuichi;
- Osonoi, Takeshi;
- Kaneto, Hideaki;
- Kosugi, Keisuke;
- Umayahara, Yutaka;
- Yamamoto, Tsunehiko;
- Matsumoto, Kazunari;
- Yokoyama, Hiroki;
- Tsugawa, Mamiko;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka;
- Collaborators on the Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE) Trial
Publication type:
journal article
Sitagliptin Attenuates the Progression of Carotid Intima-Media Thickening in Insulin-Treated Patients With Type 2 Diabetes: The Sitagliptin Preventive Study of Intima-Media Thickness Evaluation (SPIKE): A Randomized Controlled Trial.
Published in:
2016
By:
- Tomoya Mita;
- Naoto Katakami;
- Toshihiko Shiraiwa;
- Hidenori Yoshii;
- Tomio Onuma;
- Nobuichi Kuribayashi;
- Takeshi Osonoi;
- Hideaki Kaneto;
- Keisuke Kosugi;
- Yutaka Umayahara;
- Tsunehiko Yamamoto;
- Kazunari Matsumoto;
- Hiroki Yokoyama;
- Mamiko Tsugawa;
- Masahiko Gosho;
- Iichiro Shimomura;
- Hirotaka Watada;
- Mita, Tomoya;
- Katakami, Naoto;
- Shiraiwa, Toshihiko
Publication type:
journal article
Alogliptin, a Dipeptidyl Peptidase 4 Inhibitor, Prevents the Progression of Carotid Atherosclerosis in Patients With Type 2 Diabetes: The Study of Preventive Effects of Alogliptin on Diabetic Atherosclerosis (SPEAD-A).
Published in:
2016
By:
- Tomoya Mita;
- Naoto Katakami;
- Hidenori Yoshii;
- Tomio Onuma;
- Hideaki Kaneto;
- Takeshi Osonoi;
- Toshihiko Shiraiwa;
- Keisuke Kosugi;
- Yutaka Umayahara;
- Tsunehiko Yamamoto;
- Hiroki Yokoyama;
- Nobuichi Kuribayashi;
- Hideaki Jinnouchi;
- Masahiko Gosho;
- Iichiro Shimomura;
- Hirotaka Watada;
- Mita, Tomoya;
- Katakami, Naoto;
- Yoshii, Hidenori;
- Onuma, Tomio
Publication type:
journal article
Basal insulin requirement is ~30% of the total daily insulin dose in type 1 diabetic patients who use the insulin pump.
Published in:
2011
By:
- Kuroda A;
- Kaneto H;
- Yasuda T;
- Matsuhisa M;
- Miyashita K;
- Fujiki N;
- Fujisawa K;
- Yamamoto T;
- Takahara M;
- Sakamoto F;
- Matsuoka TA;
- Shimomura I;
- Kuroda, Akio;
- Kaneto, Hideaki;
- Yasuda, Tetsuyuki;
- Matsuhisa, Munehide;
- Miyashita, Kazuyuki;
- Fujiki, Noritaka;
- Fujisawa, Keiko;
- Yamamoto, Tsunehiko
Publication type:
journal article
Basal Insulin Requirement Is ~30% of the Total Daily Insulin Dose in Type 1 Diabetic Patients Who Use the Insulin Pump.
Published in:
Diabetes Care, 2011, v. 34, n. 5, p. 1089, doi. 10.2337/dc10-2149
By:
- KURODA, AKIO;
- KANETO, HIDEAKI;
- YASUDA, TETSUYUKI;
- MATSUHISA, MUNEHIDE;
- MIYASHITA, KAZUYUKI;
- FUJIKI, NORITAKA;
- FUJISAWA, KEIKO;
- YAMAMOTO, TSUNEHIKO;
- TAKAHARA, MITSUYOSHI;
- SAKAMOTO, FUMIE;
- MATSUOKA, TAKA-AKI;
- SHIMOMURA, ITCHIRO
Publication type:
Article
Long-term efficacy and safety of early alogliptin initiation in subjects with type 2 diabetes: an extension of the SPEAD-A study.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41036-1
By:
- Mita, Tomoya;
- Katakami, Naoto;
- Yoshii, Hidenori;
- Onuma, Tomio;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Shiraiwa, Toshihiko;
- Yasuda, Tetsuyuki;
- Umayahara, Yutaka;
- Yamamoto, Tsunehiko;
- Yokoyama, Hiroki;
- Kuribayashi, Nobuichi;
- Jinnouchi, Hideaki;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka
Publication type:
Article
Long-term efficacy and safety of early alogliptin initiation in subjects with type 2 diabetes: an extension of the SPEAD-A study.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-41036-1
By:
- Mita, Tomoya;
- Katakami, Naoto;
- Yoshii, Hidenori;
- Onuma, Tomio;
- Kaneto, Hideaki;
- Osonoi, Takeshi;
- Shiraiwa, Toshihiko;
- Yasuda, Tetsuyuki;
- Umayahara, Yutaka;
- Yamamoto, Tsunehiko;
- Yokoyama, Hiroki;
- Kuribayashi, Nobuichi;
- Jinnouchi, Hideaki;
- Gosho, Masahiko;
- Shimomura, Iichiro;
- Watada, Hirotaka
Publication type:
Article
The MafA Transcription Factor Becomes Essential to Islet β-Cells Soon After Birth.
Published in:
Diabetes, 2014, v. 63, n. 6, p. 1994, doi. 10.2337/db13-1001
By:
- Yan Hang;
- Tsunehiko Yamamoto;
- Benninger, Richard K.P.;
- Brissova, Marcela;
- Min Guo;
- Bush, Will;
- Piston, David W.;
- Powers, Alvin C.;
- Magnuson, Mark;
- Thurmond, Debbie C.;
- Stein, Roland
Publication type:
Article
Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.
Published in:
2010
By:
- Miyazaki S;
- Taniguchi H;
- Moritoh Y;
- Tashiro F;
- Yamamoto T;
- Yamato E;
- Ikegami H;
- Ozato K;
- Miyazaki J;
- Miyazaki, Satsuki;
- Taniguchi, Hidenori;
- Moritoh, Yusuke;
- Tashiro, Fumi;
- Yamamoto, Tsunehiko;
- Yamato, Eiji;
- Ikegami, Hiroshi;
- Ozato, Keiko;
- Miyazaki, Jun-ichi
Publication type:
journal article
Nuclear Hormone Retinoid X Receptor (RXR) Negatively Regulates the Glucose-Stimulated Insulin Secretion of Pancreatic β-cells.
Published in:
Diabetes, 2010, v. 59, n. 11, p. 2854, doi. 10.2337/db09-1897
By:
- Miyazaki, Satsuki;
- Taniguchi, Hidenori;
- Moritoh, Yusuke;
- Tashiro, Fumi;
- Yamamoto, Tsunehiko;
- Yamato, Eiji;
- Ikegami, Hiroshi;
- Ozato, Keiko;
- Miyazaki, Jun-ichi
Publication type:
Article
MafA and MafB regulate genes critical to beta-cells in a unique temporal manner.
Published in:
2010
By:
- Artner I;
- Hang Y;
- Mazur M;
- Yamamoto T;
- Guo M;
- Lindner J;
- Magnuson MA;
- Stein R;
- Artner, Isabella;
- Hang, Yan;
- Mazur, Magdalena;
- Yamamoto, Tsunehiko;
- Guo, Min;
- Lindner, Jill;
- Magnuson, Mark A;
- Stein, Roland
Publication type:
journal article
MafA and MafB Regulate Genes Critical to β-Cells in a Unique Temporal Manner.
Published in:
Diabetes, 2010, v. 59, n. 10, p. 2530, doi. 10.2337/db10-0190
By:
- Artner, Isabella;
- Yan Hang;
- Mazur, Magdalena;
- Yamamoto, Tsunehiko;
- Guo, Min;
- Lindner, Jill;
- Magnuson, Mark A.;
- Stein, Roland
Publication type:
Article
Regulation of MafA expression in pancreatic beta-cells in db/db mice with diabetes.
Published in:
2010
By:
- Matsuoka TA;
- Kaneto H;
- Miyatsuka T;
- Yamamoto T;
- Yamamoto K;
- Kato K;
- Shimomura I;
- Stein R;
- Matsuhisa M;
- Matsuoka, Taka-aki;
- Kaneto, Hideaki;
- Miyatsuka, Takeshi;
- Yamamoto, Tsunehiko;
- Yamamoto, Kaoru;
- Kato, Ken;
- Shimomura, Iichiro;
- Stein, Roland;
- Matsuhisa, Munehide
Publication type:
journal article
Regulation of MafA Expression in Pancreatic βCells in db/db Mice With Diabetes.
Published in:
Diabetes, 2010, v. 59, n. 7, p. 1709, doi. 10.2337/db08-0693
By:
- Matsuoka, Taka-aki;
- Kaneto, Hideaki;
- Miyatsuka, Takeshi;
- Yamamoto, Tsunehiko;
- Yamamoto, Kaoru;
- Kato, Ken;
- Shimomura, Iichiro;
- Stein, Roland;
- Matsuhisa, Munehide
Publication type:
Article

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