Works by Yamakado, Hodaka

Results: 43

A RaPID Macrocyclic Peptide That Inhibits the Formation of α‐Synuclein Amyloid Fibrils.

Published in:

ChemBioChem, 2023, v. 24, n. 12, p. 1, doi. 10.1002/cbic.202300320

By:

Ikenoue, Tatsuya;
Oono, Miki;
So, Masatomo;
Yamakado, Hodaka;
Arata, Toshiaki;
Takahashi, Ryosuke;
Kawata, Yasushi;
Suga, Hiroaki

Publication type:

Article

Ca<sup>2+</sup>–Calmodulin–Calcineurin Signaling Modulates α‐Synuclein Transmission.

Published in:

Movement Disorders, 2023, v. 38, n. 6, p. 1056, doi. 10.1002/mds.29401

By:

Ueda, Jun;
Uemura, Norihito;
Ishimoto, Tomoyuki;
Taguchi, Tomoyuki;
Sawamura, Masanori;
Nakanishi, Etsuro;
Ikuno, Masashi;
Matsuzawa, Shuichi;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Lewy Body Disease Primate Model with α-Synuclein Propagation from the Olfactory Bulb.

Published in:

2022

By:

Sawamura, Masanori;
Onoe, Hirotaka;
Tsukada, Hideo;
Isa, Kaoru;
Yamakado, Hodaka;
Okuda, Shinya;
Ikuno, Masashi;
Hatanaka, Yusuke;
Murayama, Shigeo;
Uemura, Norihito;
Isa, Tadashi;
Takahashi, Ryosuke

Publication type:

journal article

Membranes and Organelle in Lewy Bodies: The Mastermind or the Bystander?

Published in:

2021

By:

Ishimoto, Tomoyuki;
Yamakado, Hodaka

Publication type:

journal article

α‐Synuclein Spread from Olfactory Bulb Causes Hyposmia, Anxiety, and Memory Loss in BAC‐SNCA Mice.

Published in:

Movement Disorders, 2021, v. 36, n. 9, p. 2036, doi. 10.1002/mds.28512

By:

Uemura, Norihito;
Ueda, Jun;
Yoshihara, Toru;
Ikuno, Masashi;
Uemura, Maiko T.;
Yamakado, Hodaka;
Asano, Masahide;
Trojanowski, John Q.;
Takahashi, Ryosuke

Publication type:

Article

Perampanel Inhibits α‐Synuclein Transmission in Parkinson's Disease Models.

Published in:

Movement Disorders, 2021, v. 36, n. 7, p. 1554, doi. 10.1002/mds.28558

By:

Ueda, Jun;
Uemura, Norihito;
Sawamura, Masanori;
Taguchi, Tomoyuki;
Ikuno, Masashi;
Kaji, Seiji;
Taruno, Yosuke;
Matsuzawa, Shuichi;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

TPPP/p25α Is an old and new therapeutic target in multiple system atrophy.

Published in:

2019

By:

Ishimoto, Tomoyuki;
Yamakado, Hodaka

Publication type:

Editorial

Advance in PD research explored a new field on ubiquitin biology.

Published in:

2014

By:

Yamakado, Hodaka

Publication type:

Editorial

The function of parkin: Revisited.

Published in:

Movement Disorders, 2013, v. 28, n. 14, p. 1936, doi. 10.1002/mds.25711

By:

Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Genetic correction will be a standard method for the patient-derived ips cell research?

Published in:

Movement Disorders, 2013, v. 28, n. 14, p. 1935, doi. 10.1002/mds.25710

By:

Takahashi, Ryosuke;
Yamakado, Hodaka

Publication type:

Article

A novel mouse model for investigating α-synuclein aggregates in oligodendrocytes: implications for the glial cytoplasmic inclusions in multiple system atrophy.

Published in:

Molecular Brain, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13041-024-01104-7

By:

Ishimoto, Tomoyuki;
Oono, Miki;
Kaji, Seiji;
Ayaki, Takashi;
Nishida, Katsuya;
Funakawa, Itaru;
Maki, Takakuni;
Matsuzawa, Shu-ichi;
Takahashi, Ryosuke;
Yamakado, Hodaka

Publication type:

Article

Viable Neuronopathic Gaucher Disease Model in Medaka (Oryzias latipes) Displays Axonal Accumulation of Alpha-Synuclein.

Published in:

PLoS Genetics, 2015, v. 11, n. 4, p. 1, doi. 10.1371/journal.pgen.1005065

By:

Uemura, Norihito;
Koike, Masato;
Ansai, Satoshi;
Kinoshita, Masato;
Ishikawa-Fujiwara, Tomoko;
Matsui, Hideaki;
Naruse, Kiyoshi;
Sakamoto, Naoaki;
Uchiyama, Yasuo;
Todo, Takeshi;
Takeda, Shunichi;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Cellular analysis of SOD1 protein-aggregation propensity and toxicity: a case of ALS with slow progression harboring homozygous SOD1-D92G mutation.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-16871-3

By:

Sawamura, Masanori;
Imamura, Keiko;
Hikawa, Rie;
Enami, Takako;
Nagahashi, Ayako;
Yamakado, Hodaka;
Ichijo, Hidenori;
Fujisawa, Takao;
Yamashita, Hirofumi;
Minamiyama, Sumio;
Kaido, Misako;
Wada, Hiromi;
Urushitani, Makoto;
Inoue, Haruhisa;
Egawa, Naohiro;
Takahashi, Ryosuke

Publication type:

Article

Cocaine and Phenylephrine Eye Drop Test for Parkinson Disease.

Published in:

2005

By:

Sawada, Hideyuki;
Yamakawa, Kentarou;
Yamakado, Hodaka;
Hosokawa, Ryohei;
Ohba, Muneo;
Miyamoto, Kazuaki;
Kawamura, Takashi;
Shimohama, Shun

Publication type:

Letter

Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).

Published in:

Molecular Brain, 2021, v. 14, n. 1, p. 1, doi. 10.1186/s13041-021-00790-x

By:

Nakanishi, Etsuro;
Uemura, Norihito;
Akiyama, Hisako;
Kinoshita, Masato;
Masanori, Sawamura;
Taruno, Yosuke;
Yamakado, Hodaka;
Matsuzawa, Shu-ichi;
Takeda, Shunichi;
Hirabayashi, Yoshio;
Takahashi, Ryosuke

Publication type:

Article

Immunotherapy targeting toll-like receptor 2 alleviates neurodegeneration in models of synucleinopathy by modulating α-synuclein transmission and neuroinflammation.

Published in:

Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0276-2

By:

Kim, Changyoun;
Spencer, Brian;
Rockenstein, Edward;
Yamakado, Hodaka;
Mante, Michael;
Adame, Anthony;
Fields, Jerel Adam;
Masliah, Deborah;
Iba, Michiyo;
Lee, He-Jin;
Rissman, Robert A.;
Lee, Seung-Jae;
Masliah, Eliezer

Publication type:

Article

Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.

Published in:

Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0257-5

By:

Uemura, Norihito;
Yagi, Hisashi;
Uemura, Maiko T.;
Hatanaka, Yusuke;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Thigh muscle MRI findings in myopathy associated with anti-mitochondrial antibody.

Published in:

2020

By:

Minamiyama, Sumio;
Ueda, Sakiho;
Nakashima, Ran;
Yamakado, Hodaka;
Sakato, Yusuke;
Yamashita, Hirofumi;
Sawamoto, Nobukatsu;
Fujimoto, Ryota;
Nishino, Ichizo;
Urushitani, Makoto;
Mimori, Tsuneyo;
Takahashi, Ryosuke

Publication type:

journal article

Striatal-Inoculation of α-Synuclein Preformed Fibrils Aggravated the Phenotypes of REM Sleep without Atonia in A53T BAC-SNCA Transgenic Mice.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 21, p. 13390, doi. 10.3390/ijms232113390

By:

Okuda, Shinya;
Nakayama, Takeo;
Uemura, Norihito;
Hikawa, Rie;
Ikuno, Masashi;
Yamakado, Hodaka;
Inoue, Haruhisa;
Tachibana, Naoko;
Hayashi, Yu;
Takahashi, Ryosuke;
Egawa, Naohiro

Publication type:

Article

Animal Model for Prodromal Parkinson's Disease.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 6, p. 1961, doi. 10.3390/ijms21061961

By:

Taguchi, Tomoyuki;
Ikuno, Masashi;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Diagnostic utility of FDG-PET in neurolymphomatosis: report of five cases.

Published in:

Journal of Neurology, 2016, v. 263, n. 9, p. 1719, doi. 10.1007/s00415-016-8190-4

By:

Kinoshita, Hisanori;
Yamakado, Hodaka;
Kitano, Toshiyuki;
Kitamura, Akihiro;
Yamashita, Hirofumi;
Miyamoto, Masakazu;
Hitomi, Takefumi;
Okada, Tomohisa;
Nakamoto, Yuji;
Sawamoto, Nobukatsu;
Takaori-Kondo, Akifumi;
Takahashi, Ryosuke

Publication type:

Article

DOPAnization of tyrosine in α-synuclein by tyrosine hydroxylase leads to the formation of oligomers.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34555-4

By:

Jin, Mingyue;
Matsumoto, Sakiko;
Ayaki, Takashi;
Yamakado, Hodaka;
Taguchi, Tomoyuki;
Togawa, Natsuko;
Konno, Ayumu;
Hirai, Hirokazu;
Nakajima, Hiroshi;
Komai, Shoji;
Ishida, Ryuichi;
Chiba, Syuhei;
Takahashi, Ryosuke;
Takao, Toshifumi;
Hirotsune, Shinji

Publication type:

Article

Exploring the Pathogenetic Mechanisms underlying Parkinson's Disease in Medaka Fish.

Published in:

Journal of Parkinson's Disease, 2014, v. 4, n. 2, p. 301, doi. 10.3233/JPD-130289

By:

Matsui, Hideaki;
Uemura, Norihito;
Yamakado, Hodaka;
Takeda, Shunichi;
Takahashi, Ryosuke

Publication type:

Article

Neural substrates underlying distinct dual cognitive syndromes in Parkinson's disease.

Published in:

European Journal of Neurology, 2025, v. 32, n. 1, p. 1, doi. 10.1111/ene.70022

By:

Yoshimura, Kenji;
Shima, Atsushi;
Kambe, Daisuke;
Furukawa, Koji;
Nishida, Akira;
Wada, Ikko;
Sakato, Yusuke;
Sakamaki‐Tsukita, Haruhi;
Terada, Yuta;
Yamakado, Hodaka;
Taruno, Yosuke;
Nakanishi, Etsuro;
Sawamura, Masanori;
Fujimoto, Koji;
Fushimi, Yasutaka;
Okada, Tomohisa;
Nakamoto, Yuji;
Hanakawa, Takashi;
Takahashi, Ryosuke;
Sawamoto, Nobukatsu

Publication type:

Article

Idiopathic Parkinson's disease patient-derived induced pluripotent stem cells function as midbrain dopaminergic neurons in rodent brains.

Published in:

Journal of Neuroscience Research, 2017, v. 95, n. 9, p. 1829, doi. 10.1002/jnr.24014

By:

Kikuchi, Tetsuhiro;
Morizane, Asuka;
Doi, Daisuke;
Okita, Keisuke;
Nakagawa, Masato;
Yamakado, Hodaka;
Inoue, Haruhisa;
Takahashi, Ryosuke;
Takahashi, Jun

Publication type:

Article

CHRONIC SLEEP FRAGMENTATION ACCELERATES THE DEVELOPMENT OF PRODROMAL SYMPTOMS AND PATHOLOGICAL CHANGES IN PARKINSON' S DISEASE MODEL MICE.

Published in:

International Journal of Neuropsychopharmacology, 2025, v. 28, p. i249, doi. 10.1093/ijnp/pyae059.437

By:

Masayuki Miyazaki;
Hiroko Yagihara;
Hiromi Fujita;
Hodaka Yamakado;
Keiji Wada;
Minakawa, Eiko N.

Publication type:

Article

Reduced Enhancement of Memory for Faces Encoded by Semantic and Socioemotional Processes in Patients with Parkinson's Disease.

Published in:

Journal of the International Neuropsychological Society, 2020, v. 26, n. 4, p. 418, doi. 10.1017/S1355617719001280

By:

Park, Paeksoon;
Yamakado, Hodaka;
Takahashi, Ryosuke;
Dote, Shikiho;
Ubukata, Shiho;
Murai, Toshiya;
Tsukiura, Takashi

Publication type:

Article

Insights into the pathogenesis of multiple system atrophy: focus on glial cytoplasmic inclusions.

Published in:

Translational Neurodegeneration, 2020, v. 9, n. 1, p. 1, doi. 10.1186/s40035-020-0185-5

By:

Kaji, Seiji;
Maki, Takakuni;
Ishimoto, Tomoyuki;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Susceptibility to erastin‐induced ferroptosis decreases during maturation in a human oligodendrocyte cell line.

Published in:

FEBS Open Bio, 2020, v. 10, n. 9, p. 1758, doi. 10.1002/2211-5463.12923

By:

Hoshino, Tomonori;
Yamakado, Hodaka;
Takahashi, Ryosuke;
Matsuzawa, Shu‐ichi

Publication type:

Article

Delineating three distinct spatiotemporal patterns of brain atrophy in Parkinson's disease.

Published in:

Brain: A Journal of Neurology, 2024, v. 147, n. 11, p. 3702, doi. 10.1093/brain/awae303

By:

Sakato, Yusuke;
Shima, Atsushi;
Terada, Yuta;
Takeda, Kiyoaki;
Sakamaki-Tsukita, Haruhi;
Nishida, Akira;
Yoshimura, Kenji;
Wada, Ikko;
Furukawa, Koji;
Kambe, Daisuke;
Togo, Hiroki;
Mukai, Yohei;
Sawamura, Masanori;
Nakanishi, Etsuro;
Yamakado, Hodaka;
Fushimi, Yasutaka;
Okada, Tomohisa;
Takahashi, Yuji;
Nakamoto, Yuji;
Takahashi, Ryosuke

Publication type:

Article

α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.

Published in:

Brain: A Journal of Neurology, 2020, v. 143, n. 1, p. 249, doi. 10.1093/brain/awz380

By:

Taguchi, Tomoyuki;
Ikuno, Masashi;
Hondo, Mari;
Parajuli, Laxmi Kumar;
Taguchi, Katsutoshi;
Ueda, Jun;
Sawamura, Masanori;
Okuda, Shinya;
Nakanishi, Etsuro;
Hara, Junko;
Uemura, Norihito;
Hatanaka, Yusuke;
Ayaki, Takashi;
Matsuzawa, Shuichi;
Tanaka, Masaki;
El-Agnaf, Omar M A;
Koike, Masato;
Yanagisawa, Masashi;
Uemura, Maiko T;
Yamakado, Hodaka

Publication type:

Article

α-Synuclein BAC transgenic mice exhibit RBD-like behaviour and hyposmia: a prodromal Parkinson's disease model.

Published in:

2019

By:

Taguchi, Tomoyuki;
Ikuno, Masashi;
Hondo, Mari;
Parajuli, Laxmi Kumar;
Taguchi, Katsutoshi;
Ueda, Jun;
Sawamura, Masanori;
Okuda, Shinya;
Nakanishi, Etsuro;
Hara, Junko;
Uemura, Norihito;
Hatanaka, Yusuke;
Ayaki, Takashi;
Matsuzawa, Shuichi;
Tanaka, Masaki;
El-Agnaf, Omar M A;
Koike, Masato;
Yanagisawa, Masashi;
Uemura, Maiko T;
Yamakado, Hodaka

Publication type:

journal article

A progressive dopaminergic phenotype associated with neurotoxic conversion of α-synuclein in BAC-transgenic rats.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 2, p. 412, doi. 10.1093/brain/aws358

By:

Nuber, Silke;
Harmuth, Florian;
Kohl, Zacharias;
Adame, Anthony;
Trejo, Margaritha;
Schönig, Kai;
Zimmermann, Frank;
Bauer, Claudia;
Casadei, Nicolas;
Giel, Christiane;
Calaminus, Carsten;
Pichler, Bernd J.;
Jensen, Poul H.;
Müller, Christian P.;
Amato, Davide;
Kornhuber, Johannes;
Teismann, Peter;
Yamakado, Hodaka;
Takahashi, Ryosuke;
Winkler, Juergen

Publication type:

Article

Motor Progression and Nigrostriatal Neurodegeneration in Parkinson Disease.

Published in:

Annals of Neurology, 2022, v. 92, n. 1, p. 110, doi. 10.1002/ana.26373

By:

Furukawa, Koji;
Shima, Atsushi;
Kambe, Daisuke;
Nishida, Akira;
Wada, Ikko;
Sakamaki, Haruhi;
Yoshimura, Kenji;
Terada, Yuta;
Sakato, Yusuke;
Mitsuhashi, Masahiro;
Sawamura, Masanori;
Nakanishi, Etsuro;
Taruno, Yosuke;
Yamakado, Hodaka;
Fushimi, Yasutaka;
Okada, Tomohisa;
Nakamoto, Yuji;
Takahashi, Ryosuke;
Sawamoto, Nobukatsu

Publication type:

Article

Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN).

Published in:

American Journal of Case Reports, 2018, v. 19, p. 1249, doi. 10.12659/AJCR.911300

By:

Akio Sakamoto;
Arai, Ryuzo;
Takeshi Okamoto;
Yosuke Yamada;
Hodaka Yamakado;
Shuichi Matsuda

Publication type:

Article

Correction to: Inoculation of α-synuclein preformed fibrils into the mouse gastrointestinal tract induces Lewy body-like aggregates in the brainstem via the vagus nerve.

Published in:

2019

By:

Uemura, Norihito;
Yagi, Hisashi;
Uemura, Maiko T.;
Hatanaka, Yusuke;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Correction Notice

The Gut–Brain Axis Based on α-Synuclein Propagation—Clinical, Neuropathological, and Experimental Evidence.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 3994, doi. 10.3390/ijms26093994

By:

Takahashi, Ryosuke;
Yamakado, Hodaka;
Uemura, Norihito;
Taguchi, Tomoyuki;
Ueda, Jun

Publication type:

Article

BCAS1-positive immature oligodendrocytes are affected by the α-synuclein-induced pathology of multiple system atrophy.

Published in:

Acta Neuropathologica Communications, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40478-020-00997-4

By:

Kaji, Seiji;
Maki, Takakuni;
Ueda, Jun;
Ishimoto, Tomoyuki;
Inoue, Yutaka;
Yasuda, Ken;
Sawamura, Masanori;
Hikawa, Rie;
Ayaki, Takashi;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Developmental Changes in Dendritic Spine Morphology in the Striatum and Their Alteration in an A53T a-Synuclein Transgenic Mouse Model of Parkinson’s Disease.

Published in:

eNeuro, 2020, v. 7, n. 4, p. 1, doi. 10.1523/ENEURO.0072-20.2020

By:

Parajuli, Laxmi Kumar;
Ken Wako;
Suiki Maruo;
Soichiro Kakuta;
Tomoyuki Taguchi;
Masashi Ikuno;
Hodaka Yamakado;
Ryosuke Takahashi;
Masato Koike

Publication type:

Article

GBA haploinsufficiency accelerates alpha-synuclein pathology with altered lipid metabolism in a prodromal model of Parkinson's disease.

Published in:

Human Molecular Genetics, 2019, v. 28, n. 11, p. 1894, doi. 10.1093/hmg/ddz030

By:

Ikuno, Masashi;
Yamakado, Hodaka;
Akiyama, Hisako;
Parajuli, Laxmi Kumar;
Taguchi, Katsutoshi;
Hara, Junko;
Uemura, Norihito;
Hatanaka, Yusuke;
Higaki, Katsumi;
Ohno, Kousaku;
Tanaka, Masaki;
Koike, Masato;
Hirabayashi, Yoshio;
Takahashi, Ryosuke

Publication type:

Article

PINK1 and Parkin complementarily protect dopaminergic neurons in vertebrates.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 12, p. 2423, doi. 10.1093/hmg/ddt095

By:

Matsui, Hideaki;
Gavinio, Roberto;
Asano, Takeshi;
Uemura, Norihito;
Ito, Hidefumi;
Taniguchi, Yoshihito;
Kobayashi, Yoshito;
Maki, Takakuni;
Shen, Jie;
Takeda, Shunichi;
Uemura, Kengo;
Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Experimental Animal Models of Prodromal Parkinson's Disease.

Published in:

Journal of Parkinson's Disease, 2024, v. 14, p. S369, doi. 10.3233/JPD-230393

By:

Yamakado, Hodaka;
Takahashi, Ryosuke

Publication type:

Article

Chronic overload of SEPT4, a parkin substrate that aggregates in Parkinson's disease, causes behavioral alterations but not neurodegeneration in mice.

Published in:

Molecular Brain, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-6606-6-35

By:

Ageta-Ishihara, Natsumi;
Yamakado, Hodaka;
Morita, Takao;
Hattori, Satoko;
Takao, Keizo;
Miyakawa, Tsuyoshi;
Takahashi, Ryosuke;
Kinoshita, Makoto

Publication type:

Article