Works by Yaghootkar, Hanieh

Results: 52

A Genetic Variant in the Seed Region of mi R-4513 Shows Pleiotropic Effects on Lipid and Glucose Homeostasis, Blood Pressure, and Coronary Artery Disease.
Published in:
Human Mutation, 2014, v. 35, n. 12, p. 1524, doi. 10.1002/humu.22706
By:
- Ghanbari, Mohsen;
- de Vries, Paul S.;
- de Looper, Hans;
- Peters, Marjolein J.;
- Schurmann, Claudia;
- Yaghootkar, Hanieh;
- Dörr, Marcus;
- Frayling, Timothy M.;
- Uitterlinden, Andre G.;
- Hofman, Albert;
- van Meurs, Joyce B. J.;
- Erkeland, Stefan J.;
- Franco, Oscar H.;
- Dehghan, Abbas
Publication type:
Article
Identifying obesity subtypes: A review of studies utilising clinical biomarkers and genetic data.
Published in:
Diabetic Medicine, 2023, v. 40, n. 12, p. 1, doi. 10.1111/dme.15226
By:
- Abraham, Angela;
- Yaghootkar, Hanieh
Publication type:
Article
Genetic scores associated with favourable and unfavourable adiposity have consistent effect on metabolic profile and disease risk across diverse ethnic groups.
Published in:
Diabetic Medicine, 2023, v. 40, n. 12, p. 1, doi. 10.1111/dme.15213
By:
- Ahmed, Altayeb;
- Justo, Stephen;
- Yaghootkar, Hanieh
Publication type:
Article
Advancing a causal role of type 2 diabetes and its components in developing macro‐ and microvascular complications via genetic studies.
Published in:
Diabetic Medicine, 2022, v. 39, n. 12, p. 1, doi. 10.1111/dme.14982
By:
- Ahmed, Altayeb;
- Sattar, Naveed;
- Yaghootkar, Hanieh
Publication type:
Article
Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile.
Published in:
Diabetic Medicine, 2021, v. 38, n. 9, p. 1, doi. 10.1111/dme.14531
By:
- Heald, Adrian H.;
- Martin, Susan;
- Fachim, Helene;
- Green, Harry D.;
- Young, Katherine G.;
- Malipatil, Nagaraj;
- Siddals, Kirk;
- Cortes, Gabriela;
- Tyrrell, Jessica;
- Wood, Andrew R;
- Beaumont, Robin N.;
- Frayling, Timothy M.;
- Donn, Rachelle;
- Narayanan, Ram Prakash;
- Ollier, William;
- Gibson, Martin;
- Yaghootkar, Hanieh
Publication type:
Article
Genetic variant profiling of neonatal diabetes mellitus in Iranian patients: Unveiling 58 distinct variants in 14 genes.
Published in:
Journal of Diabetes Investigation, 2024, v. 15, n. 10, p. 1390, doi. 10.1111/jdi.14254
By:
- Mianesaz, Hamidreza;
- Ghalamkari, Safoura;
- Abbasi, Farzaneh;
- Razzaghy‐Azar, Maryam;
- Sayarifard, Fatemeh;
- Vakili, Rahim;
- Sedghi, Maryam;
- Noroozi Asl, Samaneh;
- Hosseini, Sousan;
- Amoli, Mahsa M;
- Yaghootkar, Hanieh
Publication type:
Article
Genetic Evidence Strongly Supports Managing Weight and Blood Pressure in Addition to Glycemic Control in Preventing Vascular Complications in People With Type 2 Diabetes.
Published in:
Diabetes Care, 2023, v. 46, n. 10, p. 1783, doi. 10.2337/dc23-0855
By:
- Ahmed, Altayeb;
- Amin, Hasnat;
- Drenos, Fotios;
- Sattar, Naveed;
- Yaghootkar, Hanieh
Publication type:
Article
Estimating the Effect of Liver and Pancreas Volume and Fat Content on Risk of Diabetes: A Mendelian Randomization Study.
Published in:
2022
By:
- Martin, Susan;
- Sorokin, Elena P.;
- Thomas, E. Louise;
- Sattar, Naveed;
- Cule, Madeleine;
- Bell, Jimmy D.;
- Yaghootkar, Hanieh
Publication type:
journal article
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity.
Published in:
2020
By:
- Yaghootkar, Hanieh;
- Zhang, Yiying;
- Spracklen, Cassandra N.;
- Karaderi, Tugce;
- Huang, Lam Opal;
- Bradfield, Jonathan;
- Schurmann, Claudia;
- Fine, Rebecca S.;
- Preuss, Michael H.;
- Kutalik, Zoltan;
- Wittemans, Laura B.L.;
- Lu, Yingchang;
- Metz, Sophia;
- Willems, Sara M.;
- Li-Gao, Ruifang;
- Grarup, Niels;
- Wang, Shuai;
- Molnos, Sophie;
- Sandoval-Zárate, América A.;
- Nalls, Mike A.
Publication type:
journal article
Wolcott-Rallison syndrome in Iran: a common cause of neonatal diabetes.
Published in:
Journal of Pediatric Endocrinology & Metabolism, 2019, v. 32, n. 6, p. 607, doi. 10.1515/jpem-2018-0434
By:
- Asl, Samaneh Noroozi;
- Vakili, Rahim;
- Vakili, Saba;
- Soheilipour, Fahimeh;
- Hashemipour, Mahin;
- Ghahramani, Sara;
- De Franco, Elisa;
- Yaghootkar, Hanieh
Publication type:
Article
Genetic predisposition to metabolically unfavourable adiposity and prostate cancer risk: A Mendelian randomization analysis.
Published in:
Cancer Medicine, 2023, v. 12, n. 15, p. 16482, doi. 10.1002/cam4.6220
By:
- Perez‐Cornago, Aurora;
- Smith‐Byrne, Karl;
- Hazelwood, Emma;
- Watling, Cody Z.;
- Martin, Susan;
- Frayling, Timothy;
- Lewis, Sarah;
- Martin, Richard M.;
- Yaghootkar, Hanieh;
- Travis, Ruth C.;
- Key, Timothy J.
Publication type:
Article
Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association.
Published in:
Human Molecular Genetics, 2011, v. 20, n. 20, p. 4082, doi. 10.1093/hmg/ddr328
By:
- Wood, Andrew R.;
- Hernandez, Dena G.;
- Nalls, Michael A.;
- Yaghootkar, Hanieh;
- Gibbs, J. Raphael;
- Harries, Lorna W.;
- Chong, Sean;
- Moore, Matthew;
- Weedon, Michael N.;
- Guralnik, Jack M.;
- Bandinelli, Stefania;
- Murray, Anna;
- Ferrucci, Luigi;
- Singleton, Andrew B;
- Melzer, David;
- Frayling, Timothy M.
Publication type:
Article
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Published in:
Nature Communications, 2015, v. 6, n. 1, p. 5897, doi. 10.1038/ncomms6897
By:
- Wessel, Jennifer;
- Chu, Audrey Y;
- Willems, Sara M;
- Wang, Shuai;
- Yaghootkar, Hanieh;
- Brody, Jennifer A;
- Dauriz, Marco;
- Hivert, Marie-France;
- Raghavan, Sridharan;
- Lipovich, Leonard;
- Hidalgo, Bertha;
- Fox, Keolu;
- Huffman, Jennifer E;
- An, Ping;
- Lu, Yingchang;
- Rasmussen-Torvik, Laura J;
- Grarup, Niels;
- Ehm, Margaret G;
- Li, Li;
- Baldridge, Abigail S
Publication type:
Article
Genome-wide association analyses of chronotype in 697,828 individuals provides insights into circadian rhythms.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-018-08259-7
By:
- Jones, Samuel E.;
- Lane, Jacqueline M.;
- Wood, Andrew R.;
- van Hees, Vincent T.;
- Tyrrell, Jessica;
- Beaumont, Robin N.;
- Jeffries, Aaron R.;
- Dashti, Hassan S.;
- Hillsdon, Melvyn;
- Ruth, Katherine S.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Sharp, Seth A.;
- Jie, Yingjie;
- Thompson, William D.;
- Harrison, Jamie W.;
- Dawes, Amy;
- Byrne, Enda M.;
- Tiemeier, Henning;
- Allebrandt, Karla V.
Publication type:
Article
Investigating Genetic Mutations in a Large Cohort of Iranian Patients with Congenital Hyperinsulinism.
Published in:
Journal of Clinical Research in Pediatric Endocrinology, 2022, v. 14, n. 1, p. 87, doi. 10.4274/jcrpe.galenos.2021.2021.0071
By:
- Razzaghy-Azar, Maryam;
- Saeedi, Saeedeh;
- Dayani, Sepideh Borhan;
- Enayati, Samaneh;
- Abbasi, Farzaneh;
- Hashemian, Somayyeh;
- Eshraghi, Peyman;
- Karimdadi, Siroos;
- Tajdini, Parisa;
- Vakili, Rahim;
- Amoli, Mahsa M.;
- Yaghootkar, Hanieh
Publication type:
Article
Cell Specific eQTL Analysis without Sorting Cells.
Published in:
PLoS Genetics, 2015, v. 11, n. 5, p. 1, doi. 10.1371/journal.pgen.1005223
By:
- Westra, Harm-Jan;
- Arends, Danny;
- Esko, Tõnu;
- Peters, Marjolein J.;
- Schurmann, Claudia;
- Schramm, Katharina;
- Kettunen, Johannes;
- Yaghootkar, Hanieh;
- Fairfax, Benjamin P.;
- Andiappan, Anand Kumar;
- Li, Yang;
- Fu, Jingyuan;
- Karjalainen, Juha;
- Platteel, Mathieu;
- Visschedijk, Marijn;
- Weersma, Rinse K.;
- Kasela, Silva;
- Milani, Lili;
- Tserel, Liina;
- Peterson, Pärt
Publication type:
Article
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.
Published in:
Aging Cell, 2011, v. 10, n. 5, p. 868, doi. 10.1111/j.1474-9726.2011.00726.x
By:
- Harries, Lorna W.;
- Hernandez, Dena;
- Henley, William;
- Wood, Andrew R.;
- Holly, Alice C.;
- Bradley-Smith, Rachel M.;
- Yaghootkar, Hanieh;
- Dutta, Ambarish;
- Murray, Anna;
- Frayling, Timothy M.;
- Guralnik, Jack M.;
- Bandinelli, Stefania;
- Singleton, Andrew;
- Ferrucci, Luigi;
- Melzer, David
Publication type:
Article
Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study.
Published in:
2020
By:
- Green, Harry D;
- Beaumont, Robin N;
- Wood, Andrew R;
- Hamilton, Benjamin;
- Jones, Samuel E;
- Goodhand, James R;
- Kennedy, Nicholas A;
- Ahmad, Tariq;
- Yaghootkar, Hanieh;
- Weedon, Michael N;
- Frayling, Timothy M;
- Tyrrell, Jessica
Publication type:
journal article
Using genetics to understand the causal influence of higher BMI on depression.
Published in:
2019
By:
- Tyrrell, Jessica;
- Mulugeta, Anwar;
- Wood, Andrew R;
- Zhou, Ang;
- Beaumont, Robin N;
- Tuke, Marcus A;
- Jones, Samuel E;
- Ruth, Katherine S;
- Yaghootkar, Hanieh;
- Sharp, Seth;
- Thompson, William D;
- Ji, Yingjie;
- Harrison, Jamie;
- Freathy, Rachel M;
- Murray, Anna;
- Weedon, Michael N;
- Lewis, Cathryn;
- Frayling, Timothy M;
- Hyppönen, Elina
Publication type:
journal article
Gene-obesogenic environment interactions in the UK Biobank study.
Published in:
2017
By:
- Tyrrell, Jessica;
- Wood, Andrew R.;
- Ames, Ryan M.;
- Yaghootkar, Hanieh;
- Beaumont, Robin N.;
- Jones, Samuel E.;
- Tuke, Marcus A.;
- Ruth, Katherine S.;
- Freathy, Rachel M.;
- Smith, George Davey;
- Joost, Stéphane;
- Guessous, Idris;
- Murray, Anna;
- Strachan, David P.;
- Kutalik, Zolt_n;
- Weedon, Michael N.;
- Frayling, Timothy M.;
- Davey Smith, George;
- Kutalik, Zoltán
Publication type:
journal article
Parental diabetes and birthweight in 236 030 individuals in the UK Biobank Study.
Published in:
International Journal of Epidemiology, 2013, v. 42, n. 6, p. 1714, doi. 10.1093/ije/dyt220
By:
- Tyrrell, Jessica S;
- Yaghootkar, Hanieh;
- Freathy, Rachel M;
- Hattersley, Andrew T;
- Frayling, Timothy M
Publication type:
Article
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Published in:
Science Translational Medicine, 2016, v. 8, n. 341, p. 1, doi. 10.1126/scitranslmed.aad3744
By:
- Scott, Robert A.;
- Freitag, Daniel F.;
- Li Li;
- Chu, Audrey Y.;
- Surendran, Praveen;
- Young, Robin;
- Grarup, Niels;
- Stancáková, Alena;
- Yuning Chen;
- Varga, Tibor V.;
- Yaghootkar, Hanieh;
- Jian’an Luan;
- Jing Hua Zhao;
- Willems, Sara M.;
- Wessel, Jennifer;
- Shuai Wang;
- Maruthur, Nisa;
- Michailidou, Kyriaki;
- Pirie, Ailith;
- van der Lee, Sven J.
Publication type:
Article
Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.
Published in:
PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0185083
By:
- Pilling, Luke C.;
- Atkins, Janice L.;
- Duff, Michael O.;
- Beaumont, Robin N.;
- Jones, Samuel E.;
- Tyrrell, Jessica;
- Kuo, Chia-Ling;
- Ruth, Katherine S.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Wood, Andrew R.;
- Murray, Anna;
- Weedon, Michael N.;
- Harries, Lorna W.;
- Kuchel, George A.;
- Ferrucci, Luigi;
- Frayling, Timothy M.;
- Melzer, David
Publication type:
Article
Metabolically favorable adiposity and bone mineral density: a Mendelian randomization analysis.
Published in:
Obesity (19307381), 2023, v. 31, n. 1, p. 267, doi. 10.1002/oby.23604
By:
- Bland, Victoria L.;
- Bea, Jennifer W.;
- Going, Scott B.;
- Yaghootkar, Hanieh;
- Arora, Amit;
- Ramadan, Ferris;
- Funk, Janet L.;
- Chen, Zhao;
- Klimentidis, Yann C.
Publication type:
Article
Ethnic Differences in Body Fat Deposition and Liver Fat Content in Two UK‐Based Cohorts.
Published in:
Obesity (19307381), 2020, v. 28, n. 11, p. 2142, doi. 10.1002/oby.22948
By:
- Alenaini, Wareed;
- Parkinson, James R. C.;
- McCarthy, John P.;
- Goldstone, Anthony P.;
- Wilman, Henry R.;
- Banerjee, Rajarshi;
- Yaghootkar, Hanieh;
- Bell, Jimmy D.;
- Thomas, E. Louise
Publication type:
Article
Systematic identification of trans eQTLs as putative drivers of known disease associations.
Published in:
Nature Genetics, 2013, v. 45, n. 10, p. 1238, doi. 10.1038/ng.2756
By:
- Westra, Harm-Jan;
- Peters, Marjolein J;
- Esko, Tõnu;
- Yaghootkar, Hanieh;
- Schurmann, Claudia;
- Kettunen, Johannes;
- Christiansen, Mark W;
- Fairfax, Benjamin P;
- Schramm, Katharina;
- Powell, Joseph E;
- Zhernakova, Alexandra;
- Zhernakova, Daria V;
- Veldink, Jan H;
- Van den Berg, Leonard H;
- Karjalainen, Juha;
- Withoff, Sebo;
- Uitterlinden, André G;
- Hofman, Albert;
- Rivadeneira, Fernando;
- 't Hoen, Peter A C
Publication type:
Article
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
Published in:
Nature Genetics, 2013, v. 45, n. 1, p. 76, doi. 10.1038/ng.2477
By:
- Horikoshi, Momoko;
- Yaghootkar, Hanieh;
- Mook-Kanamori, Dennis O;
- Sovio, Ulla;
- Taal, H Rob;
- Hennig, Branwen J;
- Bradfield, Jonathan P;
- St Pourcain, Beate;
- Evans, David M;
- Charoen, Pimphen;
- Kaakinen, Marika;
- Cousminer, Diana L;
- Lehtimäki, Terho;
- Kreiner-Møller, Eskil;
- Warrington, Nicole M;
- Bustamante, Mariona;
- Feenstra, Bjarke;
- Berry, Diane J;
- Thiering, Elisabeth;
- Pfab, Thiemo
Publication type:
Article
Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight.
Published in:
Human Molecular Genetics, 2022, v. 31, n. 11, p. 1762, doi. 10.1093/hmg/ddab356
By:
- Thompson, William D;
- Beaumont, Robin N;
- Kuang, Alan;
- Warrington, Nicole M;
- Ji, Yingjie;
- Tyrrell, Jessica;
- Wood, Andrew R;
- Scholtens, Denise M;
- Knight, Bridget A;
- Evans, David M;
- Jr, William L Lowe;
- Santorelli, Gillian;
- Azad, Raq;
- Mason, Dan;
- Hattersley, Andrew T;
- Frayling, Timothy M;
- Yaghootkar, Hanieh;
- Borges, Maria Carolina;
- Lawlor, Deborah A;
- Freathy, Rachel M
Publication type:
Article
Higher adiposity and mental health: causal inference using Mendelian randomization.
Published in:
Human Molecular Genetics, 2021, v. 30, n. 24, p. 2371, doi. 10.1093/hmg/ddab204
By:
- Casanova, Francesco;
- O’Loughlin, Jessica;
- Martin, Susan;
- Beaumont, Robin N.;
- Wood, Andrew R.;
- Watkins, Edward R.;
- Freathy, Rachel M.;
- Hagenaars, Saskia P.;
- Frayling, Timothy M.;
- Yaghootkar, Hanieh;
- Tyrrell, Jess
Publication type:
Article
DNA methylation and inflammation marker profiles associated with a history of depression.
Published in:
Human Molecular Genetics, 2018, v. 27, n. 16, p. 2840, doi. 10.1093/hmg/ddy199
By:
- Crawford, Bethany;
- Craig, Zoe;
- Mansell, Georgina;
- White, Isobel;
- Smith, Adam;
- Spaull, Steve;
- Imm, Jennifer;
- Hannon, Eilis;
- Wood, Andrew;
- Yaghootkar, Hanieh
Publication type:
Article
Quantifying the extent to which index event biases influence large genetic association studies.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 5, p. 1018, doi. 10.1093/hmg/ddw433
By:
- Yaghootkar, Hanieh;
- Bancks, Michael P.;
- Jones, Sam E.;
- McDaid, Aaron;
- Beaumont, Robin;
- Donnelly, Louise;
- Wood, Andrew R.;
- Campbell, Archie;
- Tyrrell, Jessica;
- Hocking, Lynne J.;
- Tuke, Marcus A.;
- Ruth, Katherine S.;
- Pearson, Ewan R.;
- Murray, Anna;
- Freathy, Rachel M.;
- Munroe, Patricia B.;
- Hayward, Caroline;
- Palmer, Colin;
- Weedon, Michael N.;
- Pankow, James S.
Publication type:
Article
Analysis with the exome array identifies multiple new independent variants in lipid loci.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 18, p. 4094, doi. 10.1093/hmg/ddw227
By:
- Kanoni, Stavroula;
- Masca, Nicholas G. D.;
- Stirrups, Kathleen E.;
- Varga, Tibor V.;
- Warren, Helen R.;
- Scott, Robert A.;
- Southam, Lorraine;
- Zhang, Weihua;
- Yaghootkar, Hanieh;
- Müller-Nurasyid, Martina;
- Couto Alves, Alexessander;
- Strawbridge, Rona J.;
- Lataniotis, Lazaros;
- Hashim, Nikman An;
- Besse, Céline;
- Boland, Anne;
- Braund, Peter S.;
- Connell, John M.;
- Dominiczak, Anna;
- Farmaki, Aliki-Eleni
Publication type:
Article
Testing the role of predicted gene knockouts in human anthropometric trait variation.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 10, p. 2082, doi. 10.1093/hmg/ddw055
By:
- Lessard, Samuel;
- Manning, Alisa K.;
- Cécile Low-Kam;
- Auer, Paul L.;
- Giri, Ayush;
- Graff, Mariaelisa;
- Schurmann, Claudia;
- Yaghootkar, Hanieh;
- Luan, Jian'an;
- Esko, Tonu;
- Karaderi, Tugce;
- Bottinger, Erwin P.;
- Yingchang Lu;
- Carlson, Chris;
- Caulfield, Mark;
- Dubé, Marie-Pierre;
- Jackson, Rebecca D.;
- Kooperberg, Charles;
- McKnight, Barbara;
- Mongrain, Ian
Publication type:
Article
Genetic studies of accelerometer-based sleep measures yield new insights into human sleep behaviour.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-09576-1
By:
- Jones, Samuel E.;
- van Hees, Vincent T.;
- Mazzotti, Diego R.;
- Marques-Vidal, Pedro;
- Sabia, Séverine;
- van der Spek, Ashley;
- Dashti, Hassan S.;
- Engmann, Jorgen;
- Kocevska, Desana;
- Tyrrell, Jessica;
- Beaumont, Robin N.;
- Hillsdon, Melvyn;
- Ruth, Katherine S.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Sharp, Seth A.;
- Ji, Yingjie;
- Harrison, Jamie W.;
- Freathy, Rachel M.;
- Murray, Anna
Publication type:
Article
Recent progress in the use of genetics to understand links between type 2 diabetes and related metabolic traits.
Published in:
Genome Biology, 2013, v. 14, n. 3, p. 203, doi. 10.1186/gb-2013-14-3-203
By:
- Yaghootkar, Hanieh;
- Frayling, Timothy M
Publication type:
Article
Machine Learning based histology phenotyping to investigate the epidemiologic and genetic basis of adipocyte morphology and cardiometabolic traits.
Published in:
PLoS Computational Biology, 2020, v. 16, n. 8, p. 1, doi. 10.1371/journal.pcbi.1008044
By:
- Glastonbury, Craig A.;
- Pulit, Sara L.;
- Honecker, Julius;
- Censin, Jenny C.;
- Laber, Samantha;
- Yaghootkar, Hanieh;
- Rahmioglu, Nilufer;
- Pastel, Emilie;
- Kos, Katerina;
- Pitt, Andrew;
- Hudson, Michelle;
- Nellåker, Christopher;
- Beer, Nicola L.;
- Hauner, Hans;
- Becker, Christian M.;
- Zondervan, Krina T.;
- Frayling, Timothy M.;
- Claussnitzer, Melina;
- Lindgren, Cecilia M.
Publication type:
Article
Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.
Published in:
PLoS Genetics, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.pgen.1006125
By:
- Jones, Samuel E.;
- Tyrrell, Jessica;
- Wood, Andrew R.;
- Beaumont, Robin N.;
- Ruth, Katherine S.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Hu, Youna;
- Teder-Laving, Maris;
- Hayward, Caroline;
- Roenneberg, Till;
- Wilson, James F.;
- Del Greco, Fabiola;
- Hicks, Andrew A.;
- Shin, Chol;
- Yun, Chang-Ho;
- Lee, Seung Ku;
- Metspalu, Andres;
- Byrne, Enda M.;
- Gehrman, Philip R.
Publication type:
Article
Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile.
Published in:
Diabetologia, 2021, v. 64, n. 12, p. 2790, doi. 10.1007/s00125-021-05570-9
By:
- Thompson, William D.;
- Beaumont, Robin N.;
- Kuang, Alan;
- Warrington, Nicole M.;
- Ji, Yingjie;
- Tyrrell, Jessica;
- Wood, Andrew R.;
- Scholtens, Denise M.;
- Knight, Bridget A.;
- Evans, David M.;
- Lowe Jr, William L.;
- Santorelli, Gillian;
- Azad, Rafaq;
- Mason, Dan;
- Hattersley, Andrew T.;
- Frayling, Timothy M.;
- Yaghootkar, Hanieh;
- Borges, Maria Carolina;
- Lawlor, Deborah A.;
- Freathy, Rachel M.
Publication type:
Article
Using genetics to decipher the link between type 2 diabetes and cancer: shared aetiology or downstream consequence?
Published in:
Diabetologia, 2020, v. 63, n. 9, p. 1706, doi. 10.1007/s00125-020-05228-y
By:
- Vincent, Emma E.;
- Yaghootkar, Hanieh
Publication type:
Article
Variants in the FTO and CDKAL1 loci have recessive effects on risk of obesity and type 2 diabetes, respectively.
Published in:
Diabetologia, 2016, v. 59, n. 6, p. 1214, doi. 10.1007/s00125-016-3908-5
By:
- Wood, Andrew;
- Tyrrell, Jessica;
- Beaumont, Robin;
- Jones, Samuel;
- Tuke, Marcus;
- Ruth, Katherine;
- Yaghootkar, Hanieh;
- Freathy, Rachel;
- Murray, Anna;
- Frayling, Timothy;
- Weedon, Michael
Publication type:
Article
Genetic evidence that lower circulating FSH levels lengthen menstrual cycle, increase age at menopause and impact female reproductive health.
Published in:
2016
By:
- Ruth, KatherineS.;
- Beaumont, Robin N.;
- Tyrrell, Jessica;
- Jones, Samuel E.;
- Tuke, Marcus A.;
- Yaghootkar, Hanieh;
- Wood, Andrew R.;
- Freathy, Rachel M.;
- Weedon, Michael N.;
- Frayling, Timothy M.;
- Murray, Anna;
- Ruth, Katherine S
Publication type:
journal article
Association of sex hormones and sex hormone-binding globulin with liver fat in men and women: an observational and Mendelian randomization study.
Published in:
Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1223162
By:
- Xinting Cai;
- Thorand, Barbara;
- Hohenester, Simon;
- Prehn, Cornelia;
- Cecil, Alexander;
- Adamski, Jerzy;
- Zeller, Tanja;
- Dennis, Andrea;
- Banerjee, Rajarshi;
- Peters, Annette;
- Yaghootkar, Hanieh;
- Nano, Jana
Publication type:
Article
Genetic Evidence for Distinct Biological Mechanisms That Link Adiposity to Type 2 Diabetes: Toward Precision Medicine.
Published in:
Diabetes, 2024, v. 73, n. 6, p. 1012, doi. 10.2337/db23-1005
By:
- Abraham, Angela;
- Cule, Madeleine;
- Thanaj, Marjola;
- Basty, Nicolas;
- Hashemloo, M. Amin;
- Sorokin, Elena P.;
- Whitcher, Brandon;
- Burgess, Stephen;
- Bell, Jimmy D.;
- Sattar, Naveed;
- Thomas, E. Louise;
- Yaghootkar, Hanieh
Publication type:
Article
Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic Disease.
Published in:
2021
By:
- Martin, Susan;
- Cule, Madeleine;
- Basty, Nicolas;
- Tyrrell, Jessica;
- Beaumont, Robin N.;
- Wood, Andrew R.;
- Frayling, Timothy M.;
- Sorokin, Elena;
- Whitcher, Brandon;
- Liu, Yi;
- Bell, Jimmy D.;
- Thomas, E. Louise;
- Yaghootkar, Hanieh
Publication type:
journal article
190-LB: Using Genetics to Uncouple Higher Adiposity from Its Adverse Metabolic Effects.
Published in:
Diabetes, 2021, v. 70, p. N.PAG, doi. 10.2337/db21-190-LB
By:
- MARTIN, SUSAN;
- TYRRELL, JESSICA;
- THOMAS, ELIZABETH L.;
- BOWN, MATTHEW;
- ELDER, JAMES T.;
- KABRHEL, CHRISTOPHER;
- PAPADIMITRIOU, NIKOS;
- GUNTER, MARC;
- VINCENT, EMMA E.;
- BELL, JIMMY D.;
- FRAYLING, TIMOTHY M.;
- YAGHOOTKAR, HANIEH
Publication type:
Article
Genetic Studies of Leptin Concentrations Implicate Leptin in the Regulation of Early Adiposity.
Published in:
Diabetes, 2020, v. 69, n. 12, p. 2806, doi. 10.2337/db20-0070
By:
- Yaghootkar, Hanieh;
- Zhang, Yiying;
- Spracklen, Cassandra N.;
- Karaderi, Tugce;
- Huang, Lam Opal;
- Bradfield, Jonathan;
- Schurmann, Claudia;
- Fine, Rebecca S.;
- Preuss, Michael H.;
- Kutalik, Zoltan;
- Wittemans, Laura B.L.;
- Lu, Yingchang;
- Metz, Sophia;
- Willems, Sara M.;
- Li-Gao, Ruifang;
- Grarup, Niels;
- Wang, Shuai;
- Molnos, Sophie;
- Sandoval-Zárate, América A.;
- Nalls, Mike A.
Publication type:
Article
A Mendelian Randomization Study Provides Evidence That Adiposity and Dyslipidemia Lead to Lower Urinary Albumin-to-Creatinine Ratio, a Marker of Microvascular Function.
Published in:
Diabetes, 2020, v. 69, n. 5, p. 1072, doi. 10.2337/db19-0862
By:
- Casanova, Francesco;
- Wood, Andrew R.;
- Yaghootkar, Hanieh;
- Beaumont, Robert N.;
- Jones, Samuel E.;
- Gooding, Kim M.;
- Aizawa, Kunihiko;
- Strain, W. David;
- Hattersley, Andrew T.;
- Khan, Faisel;
- Shore, Angela C.;
- Frayling, Timothy M.;
- Tyrrell, Jessica
Publication type:
Article
Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease.
Published in:
2016
By:
- Yaghootkar, Hanieh;
- Lotta, Luca A.;
- Tyrrell, Jessica;
- Smit, Roelof A. J.;
- Jones, Sam E.;
- Donnelly, Louise;
- Beaumont, Robin;
- Campbell, Archie;
- Tuke, Marcus A.;
- Hayward, Caroline;
- Ruth, Katherine S.;
- Padmanabhan, Sandosh;
- Wouter Jukema, J.;
- Palmer, Colin C.;
- Hattersley, Andrew;
- Freathy, Rachel M.;
- Langenberg, Claudia;
- Wareham, Nicholas J.;
- Wood, Andrew R.;
- Murray, Anna
Publication type:
journal article
Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes.
Published in:
Diabetes, 2015, v. 64, n. 7, p. 2676, doi. 10.2337/db14-1710
By:
- Fall, Tove;
- Weijia Xie;
- Poon, Wenny;
- Yaghootkar, Hanieh;
- Mägi, Reedik;
- Knowles, Joshua W.;
- Lyssenko, Valeriya;
- Weedon, Michael;
- Frayling, Timothy M.;
- Ingelsson, Erik
Publication type:
Article
Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion.
Published in:
Diabetes, 2015, v. 64, n. 6, p. 2279, doi. 10.2337/db14-1456
By:
- Yaghootkar, Hanieh;
- Stancáková, Alena;
- Freathy, Rachel M.;
- Vangipurapu, Jagadish;
- Weedon, Michael N.;
- Weijia Xie;
- Wood, Andrew R.;
- Ferrannini, Ele;
- Mari, Andrea;
- Ring, Susan M.;
- Lawlor, Debbie A.;
- Smith, George Davey;
- Jørgensen, Torben;
- Hansen, Torben;
- Pedersen, Oluf;
- Steinthorsdottir, Valgerdur;
- Guðbjartsson, Daniel F.;
- Thorleifsson, Gudmar;
- Thorsteinsdottir, Unnur;
- Stefansson, Kari
Publication type:
Article