Found: 24
Select item for more details and to access through your institution.
Concentration‐QTcF Modeling of Icenticaftor from a Randomized, Placebo‐ and Positive‐Controlled Thorough QT Study in Healthy Participants.
- Published in:
- Clinical Pharmacology in Drug Development, 2024, v. 13, n. 5, p. 572, doi. 10.1002/cpdd.1374
- By:
- Publication type:
- Article
Concentration–QTc Relationship from a Single Ascending Dose Study of ANAVEX3‐71, a Novel Sigma‐1 Receptor and Allosteric M1 Muscarinic Receptor Agonist in Development for the Treatment of Frontotemporal Dementia, Schizophrenia, and Alzheimer's Disease
- Published in:
- Clinical Pharmacology in Drug Development, 2023, v. 12, n. 9, p. 888, doi. 10.1002/cpdd.1303
- By:
- Publication type:
- Article
A randomized, single‐dose, crossover study of the effects of ulotaront on electrocardiogram intervals in subjects with schizophrenia.
- Published in:
- CTS: Clinical & Translational Science, 2023, v. 16, n. 6, p. 1063, doi. 10.1111/cts.13512
- By:
- Publication type:
- Article
Evaluation of Deutetrabenazine's Potential to Delay Cardiac Repolarization Using Concentration‐QTc Analysis.
- Published in:
- Clinical Pharmacology in Drug Development, 2023, v. 12, n. 1, p. 94, doi. 10.1002/cpdd.1161
- By:
- Publication type:
- Article
ECG Evaluation as Part of the Clinical Pharmacology Strategy in the Development of New Drugs: A Review of Current Practices and Opportunities Based on Five Case Studies.
- Published in:
- Journal of Clinical Pharmacology, 2022, v. 62, n. 12, p. 1480, doi. 10.1002/jcph.2095
- By:
- Publication type:
- Article
A Phase 1 Thorough QT/QTc Study of Therapeutic and Supratherapeutic Doses of Belumosudil in Healthy Subjects.
- Published in:
- Clinical Pharmacology in Drug Development, 2022, v. 11, n. 10, p. 1221, doi. 10.1002/cpdd.1142
- By:
- Publication type:
- Article
A thorough QTc study to evaluate the effects of oral rilzabrutinib administered alone and with ritonavir in healthy subjects.
- Published in:
- CTS: Clinical & Translational Science, 2022, v. 15, n. 6, p. 1507, doi. 10.1111/cts.13271
- By:
- Publication type:
- Article
A Phase 1 Clinical Study Evaluating the Effects of Cenobamate on the QT Interval.
- Published in:
- Clinical Pharmacology in Drug Development, 2022, v. 11, n. 4, p. 523, doi. 10.1002/cpdd.1077
- By:
- Publication type:
- Article
Omecamtiv mecarbil does not prolong QTc intervals at therapeutic concentrations.
- Published in:
- British Journal of Clinical Pharmacology, 2022, v. 88, n. 1, p. 187, doi. 10.1111/bcp.14939
- By:
- Publication type:
- Article
Safety, Pharmacokinetics, and Pharmacodynamics of Trazpiroben (TAK‐906), a Novel Selective D<sub>2</sub>/D<sub>3</sub> Receptor Antagonist: A Phase 1 Randomized, Placebo‐Controlled Single‐ and Multiple‐Dose Escalation Study in Healthy Participants
- Published in:
- Clinical Pharmacology in Drug Development, 2021, v. 10, n. 8, p. 927, doi. 10.1002/cpdd.906
- By:
- Publication type:
- Article
Evaluation of the Potential for QTc Prolongation With Repeated Oral Doses of Fedratinib in Patients With Advanced Solid Tumors.
- Published in:
- Clinical Pharmacology in Drug Development, 2021, v. 10, n. 4, p. 366, doi. 10.1002/cpdd.850
- By:
- Publication type:
- Article
The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects.
- Published in:
- 2020
- By:
- Publication type:
- journal article
The effect of the glucosylceramide synthase inhibitor lucerastat on cardiac repolarization: results from a thorough QT study in healthy subjects.
- Published in:
- Orphanet Journal of Rare Diseases, 2020, v. 15, n. 1, p. 1, doi. 10.1186/s13023-020-01582-7
- By:
- Publication type:
- Article
No QTc Prolongation With Zanubrutinib: Results of Concentration‐QTc Analysis From a Thorough QT Study in Healthy Subjects.
- Published in:
- CTS: Clinical & Translational Science, 2020, v. 13, n. 5, p. 923, doi. 10.1111/cts.12779
- By:
- Publication type:
- Article
Evaluation of Clinical Cardiac Safety of Itacitinib, a JAK1 Inhibitor, in Healthy Participants.
- Published in:
- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 6, p. 677, doi. 10.1002/cpdd.758
- By:
- Publication type:
- Article
Revefenacin, a Long‐Acting Muscarinic Antagonist, Does Not Prolong QT Interval in Healthy Subjects: Results of a Placebo‐ and Positive‐Controlled Thorough QT Study.
- Published in:
- Clinical Pharmacology in Drug Development, 2020, v. 9, n. 1, p. 130, doi. 10.1002/cpdd.732
- By:
- Publication type:
- Article
Independence screening for high dimensional nonlinear additive ODE models with applications to dynamic gene regulatory networks.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Evaluating Potential QT Effects of JNJ‐54861911, a BACE Inhibitor in Single‐ and Multiple‐Ascending Dose Studies, and a Thorough QT Trial With Additional Retrospective Confirmation, Using Concentration‐QTc Analysis.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 7, p. 952, doi. 10.1002/jcph.1087
- By:
- Publication type:
- Article
Estimation of age effect with change-points on survival of cancer patients.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Thorough QT/QTc Evaluation of the Cardiac Safety of Secnidazole at Therapeutic and Supratherapeutic Doses in Healthy Individuals.
- Published in:
- Journal of Clinical Pharmacology, 2018, v. 58, n. 3, p. 286, doi. 10.1002/jcph.1014
- By:
- Publication type:
- Article
Numerical Discretization-Based Estimation Methods for Ordinary Differential Equation Models via Penalized Spline Smoothing with Applications in Biomedical Research.
- Published in:
- Biometrics, 2012, v. 68, n. 2, p. 344, doi. 10.1111/j.1541-0420.2012.01752.x
- By:
- Publication type:
- Article
Semiparametric Analysis of Zero-Inflated Count Data.
- Published in:
- Biometrics, 2006, v. 62, n. 4, p. 996, doi. 10.1111/j.1541-0420.2006.00575.x
- By:
- Publication type:
- Article
Semi-parametric accelerated failure time regression analysis with application to interval-censored HIV/AIDS data.
- Published in:
- Statistics in Medicine, 2006, v. 25, n. 22, p. 3850, doi. 10.1002/sim.2486
- By:
- Publication type:
- Article
A semiparametric regression cure model with current status data.
- Published in:
- Biometrika, 2005, v. 92, n. 3, p. 573, doi. 10.1093/biomet/92.3.573
- By:
- Publication type:
- Article