Works by Xu, Jiake

Results: 239

Heme metabolism mediates RANKL-induced osteoclastogenesis via mitochondrial oxidative phosphorylation.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 5, p. 639, doi. 10.1093/jbmr/zjaf040

By:

Qiu, Heng;
Jin, Haiming;
Miao, Jiansen;
Li, Hui;
Chen, Junchun;
Yang, Xiaohong;
Chen, Xiaojun;
Mullin, Benjamin H;
Chen, Kai;
Gu, Ronghe;
Qin, An;
Wilson, Scott G;
Xu, Jiake

Publication type:

Article

Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01856-0

By:

Gan, Kai;
Lian, Haoyu;
Yang, Tao;
Huang, Jian;
Chen, Junchun;
Su, Yuangang;
Zhao, Jinmin;
Xu, Jiake;
Liu, Qian

Publication type:

Article

Periplogenin attenuates LPS-mediated inflammatory osteolysis through the suppression of osteoclastogenesis via reducing the NF-κB and MAPK signaling pathways.

Published in:

Cell Death Discovery, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41420-024-01856-0

By:

Gan, Kai;
Lian, Haoyu;
Yang, Tao;
Huang, Jian;
Chen, Junchun;
Su, Yuangang;
Zhao, Jinmin;
Xu, Jiake;
Liu, Qian

Publication type:

Article

Research on Loaded Contact Analysis and Tooth Wear Calculation Method of Cycloid–Pin Gear Reducer.

Published in:

Lubricants (2075-4442), 2023, v. 11, n. 10, p. 445, doi. 10.3390/lubricants11100445

By:

Wang, Yongqiang;
Wei, Bingyang;
Wang, Zhen;
Yang, Jianjun;
Xu, Jiake

Publication type:

Article

The repair and autophagy mechanisms of hypoxia‐regulated bFGF‐modified primary embryonic neural stem cells in spinal cord injury.

Published in:

Stem Cells Translational Medicine, 2020, v. 9, n. 5, p. 603, doi. 10.1002/sctm.19-0282

By:

Zhu, Sipin;
Chen, Min;
Deng, Liancheng;
Zhang, Jinjing;
Ni, Wenfei;
Wang, Xiangyang;
Yao, Felix;
Li, Xiaokun;
Xu, Huazi;
Xu, Jiake;
Xiao, Jian

Publication type:

Article

Characterisation of genetic regulatory effects for osteoporosis risk variants in human osteoclasts.

Published in:

Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-020-01997-2

By:

Mullin, Benjamin H.;
Tickner, Jennifer;
Zhu, Kun;
Kenny, Jacob;
Mullin, Shelby;
Brown, Suzanne J.;
Dudbridge, Frank;
Pavlos, Nathan J.;
Mocarski, Edward S.;
Walsh, John P.;
Xu, Jiake;
Wilson, Scott G.

Publication type:

Article

The Role of Long Non-coding RNA, Nuclear Enriched Abundant Transcript 1 (NEAT1) in Cancer and Other Pathologies.

Published in:

Biochemical Genetics, 2022, v. 60, n. 3, p. 843, doi. 10.1007/s10528-021-10138-8

By:

Zhang, Miao;
Guo, Jianmin;
Liu, Lifei;
Huang, Mei;
Li, Yuexuan;
Bennett, Samuel;
Xu, JiaKe;
Zou, Jun

Publication type:

Article

Three dimensional microstructural network of elastin, collagen, and cells in Achilles tendons.

Published in:

Journal of Orthopaedic Research, 2017, v. 35, n. 6, p. 1203, doi. 10.1002/jor.23240

By:

Pang, Xin;
Wu, Jian ‐ Ping;
Allison, Garry T.;
Xu, Jiake;
Rubenson, Jonas;
Zheng, Ming ‐ Hao;
Lloyd, David G.;
Gardiner, Bruce;
Wang, Allan;
Kirk, Thomas Brett

Publication type:

Article

Elastin fibers display a versatile microfibril network in articular cartilage depending on the mechanical microenvironments.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 9, p. 1345, doi. 10.1002/jor.22384

By:

He, Bo;
Wu, Jian Ping;
Chen, Hong Hui;
Kirk, Thomas Brett;
Xu, Jiake

Publication type:

Article

Different Subtypes of Osteosarcoma: Histopathological Patterns and Clinical Behaviour.

Published in:

Journal of Molecular Pathology, 2023, v. 4, n. 2, p. 99, doi. 10.3390/jmp4020011

By:

Rothzerg, Emel;
Xu, Jiake;
Wood, David

Publication type:

Article

Identification of Differentially Expressed Intronic Transcripts in Osteosarcoma.

Published in:

Non-Coding RNA, 2022, v. 8, n. 6, p. 73, doi. 10.3390/ncrna8060073

By:

Rothzerg, Emel;
Xu, Jiake;
Wood, David

Publication type:

Article

Pathophysiology of Myopenia in rheumatoid arthritis.

Published in:

Bone Research, 2025, v. 13, n. 1, p. 1, doi. 10.1038/s41413-025-00438-9

By:

Jin, Haiming;
Wang, Gang;
Lu, Qichen;
Rawlins, Jessica;
Chen, Junchun;
Kashyap, Saanya;
Charlesworth, Oscar;
Xu, Dan;
Dai, Lie;
Zhu, Sipin;
Xu, Jiake

Publication type:

Article

Single-Cell RNA Sequencing Reveals the Migration of Osteoclasts in Giant Cell Tumor of Bone.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.715552

By:

Feng, Wenyu;
He, Mingwei;
Jiang, Xiaohong;
Liu, Huijiang;
Xie, Tianyu;
Qin, Zhaojie;
Huang, Qian;
Liao, Shijie;
Lin, Chengsen;
He, Juliang;
Xu, Jiake;
Ma, Jie;
Liu, Yun;
Wei, Qingjun

Publication type:

Article

Effects of follicle-stimulating hormone on fat metabolism and cognitive impairment in women during menopause.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.1043237

By:

Liwei Mao;
Lian Wang;
Bennett, Samuel;
Jiake Xu;
Jun Zou

Publication type:

Article

Role of Sostdc1 in skeletal biology and cancer.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.1029646

By:

Xiaoyang Tong;
Chenyu Zhu;
Lifei Liu;
Mei Huang;
Jiake Xu;
Xi Chen;
Jun Zou

Publication type:

Article

The Effects of Asprosin on Exercise-Intervention in Metabolic Diseases.

Published in:

Frontiers in Physiology, 2022, v. 13, p. 1, doi. 10.3389/fphys.2022.907358

By:

Lifei Liu;
Yuhao Liu;
Mei Huang;
Miao Zhang;
Chenyu Zhu;
Xi Chen;
Samuel Bennett;
Jiake Xu;
Jun Zou

Publication type:

Article

PIP5k1β controls bone homeostasis through modulating both osteoclast and osteoblast differentiation.

Published in:

Journal of Molecular Cell Biology, 2020, v. 12, n. 1, p. 55, doi. 10.1093/jmcb/mjz028

By:

Zhao, Xiaoying;
Cui, Penglei;
Hu, Guoli;
Wang, Chuandong;
Jiang, Lei;
Zhao, Jingyu;
Xu, Jiake;
Zhang, Xiaoling

Publication type:

Article

RNA-seq and Single-Cell Transcriptome Analyses of TRAIL Receptors Gene Expression in Human Osteosarcoma Cells and Tissues.

Published in:

Cancer Informatics, 2023, p. 1, doi. 10.1177/11769351231161478

By:

Feng, Wenyu;
Lin, Haiyingjie;
Rothzerg, Emel;
Song, Dezhi;
Zhao, Wenxiang;
Ning, Tingting;
Wei, Qingjun;
Zhao, Jinmin;
Wood, David;
Liu, Yun;
Xu, Jiake

Publication type:

Article

RNA-seq and Single-Cell Transcriptome Analyses of TRAIL Receptors Gene Expression in Human Osteosarcoma Cells and Tissues.

Published in:

Cancer Informatics, 2023, v. 22, p. 1, doi. 10.1177/11769351231161478

By:

Wenyu Feng;
Haiyingjie Lin;
Rothzerg, Emel;
Dezhi Song;
Wenxiang Zhao;
Tingting Ning;
Qingjun Wei;
Jinmin Zhao;
Wood, David;
Yun Liu;
Jiake Xu

Publication type:

Article

Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues.

Published in:

Cancer Informatics, 2022, p. 1, doi. 10.1177/11769351221140101

By:

Rothzerg, Emel;
Feng, Wenyu;
Song, Dezhi;
Li, Hengyuan;
Wei, Qingjun;
Fox, Archa;
Wood, David;
Xu, Jiake;
Liu, Yun

Publication type:

Article

Single-Cell Transcriptome Analysis Reveals Paraspeckles Expression in Osteosarcoma Tissues.

Published in:

Cancer Informatics, 2022, v. 21, p. 1, doi. 10.1177/11769351221140101

By:

Rothzerg, Emel;
Wenyu Feng;
Dezhi Song;
Hengyuan Li;
Qingjun Wei;
Fox, Archa;
Wood, David;
Jiake Xu;
Yun Liu

Publication type:

Article

Myrislignan targets extracellular signal-regulated kinase (ERK) and modulates mitochondrial function to dampen osteoclastogenesis and ovariectomy-induced osteoporosis.

Published in:

Journal of Translational Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12967-023-04706-2

By:

Yang, Tao;
Chen, Weiwei;
Gan, Kai;
Wang, Chaofeng;
Xie, Xiaoxiao;
Su, Yuangang;
Lian, Haoyu;
Xu, Jiake;
Zhao, Jinmin;
Liu, Qian

Publication type:

Article

Secondary Segmented Modification Method of Cycloidal Gear Working Tooth Profile.

Published in:

Journal of Henan University of Science & Technology, Natural Science, 2024, v. 45, n. 2, p. II

By:

LI Tianxing;
YAO Jian;
ZHANG Yang;
XU Jiake;
LUO Limin;
GONG Linhuan

Publication type:

Article

Lysosomal biogenesis and function in osteoclasts: a comprehensive review.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1431566

By:

Junchen Jiang;
Rufeng Ren;
Weiyuan Fang;
Jiansen Miao;
Zijun Wen;
Xiangyang Wang;
Jiake Xu;
Haiming Jin

Publication type:

Article

The Effect of Exercise on the Prevention of Osteoporosis and Bone Angiogenesis.

Published in:

BioMed Research International, 2019, p. 1, doi. 10.1155/2019/8171897

By:

Tong, Xiaoyang;
Chen, Xi;
Zhang, Shihua;
Huang, Mei;
Shen, Xiaoyan;
Xu, Jiake;
Zou, Jun

Publication type:

Article

Loureirin B downregulates osteoclast differentiation of bone marrow macrophages by targeting the MAPK signaling pathway.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-18287-5

By:

Zhang, Jiahao;
Mo, Liang;
Huang, Haoran;
Xu, Jiake;
Fan, Yinuo;
Li, Weifeng;
Wang, Haibin;
Zhou, Chi;
Fang, Hanjun;
He, Wei;
Chen, Zhenqiu;
Liu, Yuhao

Publication type:

Article

VIKE: vehicular IKE for context-awareness.

Published in:

Wireless Networks (10220038), 2015, v. 21, n. 4, p. 1343, doi. 10.1007/s11276-014-0856-1

By:

Xu, Jiake;
Liu, Yanheng;
Wang, Jian;
Deng, Weiwen;
Ernst, Thierry

Publication type:

Article

Massage Alleviates Delayed Onset Muscle Soreness after Strenuous Exercise: A Systematic Review and Meta-Analysis.

Published in:

Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00747

By:

Jianmin Guo;
Linjin Li;
Yuxiang Gong;
Rong Zhu;
Jiake Xu;
Jun Zou;
Xi Chen

Publication type:

Article

Identification of Differentially Expressed Genes and Molecular Pathways Involved in Osteoclastogenesis Using RNA-seq.

Published in:

Genes, 2023, v. 14, n. 4, p. 916, doi. 10.3390/genes14040916

By:

Rashid, Sarah;
Wilson, Scott G.;
Zhu, Kun;
Walsh, John P.;
Xu, Jiake;
Mullin, Benjamin H.

Publication type:

Article

Upregulation of 15 Antisense Long Non-Coding RNAs in Osteosarcoma.

Published in:

Genes, 2021, v. 12, n. 8, p. 1132, doi. 10.3390/genes12081132

By:

Rothzerg, Emel;
Ho, Xuan Dung;
Xu, Jiake;
Wood, David;
Märtson, Aare;
Kõks, Sulev

Publication type:

Article

Optogenetically modified human embryonic stem cell-derived otic neurons establish functional synaptic connection with cochlear nuclei.

Published in:

Journal of Tissue Engineering, 2024, p. 1, doi. 10.1177/20417314241265198

By:

Chen, Yanni;
Mu, Wenbo;
Wu, Yongkang;
Xu, Jiake;
Li, Xiaofang;
Hu, Hui;
Wang, Siqi;
Wang, Dali;
Hui, Bin;
Wang, Lang;
Dong, Yi;
Chen, Wei

Publication type:

Article

Light‐Triggered Biomimetic Nanoerythrocyte for Tumor‐Targeted Lung Metastatic Combination Therapy of Malignant Melanoma.

Published in:

Small, 2018, v. 14, n. 38, p. 1, doi. 10.1002/smll.201801754

By:

Liu, Wen;
Ruan, Miaoliang;
Wang, Yanming;
Song, Rongguang;
Ji, Xin;
Xu, Jiake;
Dai, Jian;
Xue, Wei

Publication type:

Article

Maackiain dampens osteoclastogenesis via attenuating RANKL‐stimulated NF‐κB signalling pathway and NFATc1 activity.

Published in:

Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 21, p. 12308, doi. 10.1111/jcmm.15647

By:

Liu, Yuhao;
Zeng, Weizai;
Ma, Chao;
Wang, Ziyi;
Wang, Chao;
Li, Shaobin;
He, Wei;
Zhang, Qingwen;
Xu, Jiake;
Zhou, Chi

Publication type:

Article

Dracorhodin perchlorate inhibits osteoclastogenesis through repressing RANKL‐stimulated NFATc1 activity.

Published in:

Journal of Cellular & Molecular Medicine, 2020, v. 24, n. 6, p. 3303, doi. 10.1111/jcmm.15003

By:

Liu, Yuhao;
Wang, Ziyi;
Ma, Chao;
Wei, Zhenquan;
Chen, Kai;
Wang, Chao;
Zhou, Chi;
Chen, Leilei;
Zhang, Qingwen;
Chen, Zhenqiu;
He, Wei;
Xu, Jiake

Publication type:

Article

Astilbin prevents bone loss in ovariectomized mice through the inhibition of RANKL‐induced osteoclastogenesis.

Published in:

Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 12, p. 8355, doi. 10.1111/jcmm.14713

By:

Jin, Haiming;
Wang, Qingqing;
Chen, Kai;
Xu, Ke;
Pan, Hao;
Chu, Feifan;
Ye, Zhen;
Wang, Ziyi;
Tickner, Jennifer;
Qiu, Heng;
Wang, Chao;
Kenny, Jacob;
Xu, Huazi;
Wang, Te;
Xu, Jiake

Publication type:

Article

Asperpyrone A attenuates RANKL‐induced osteoclast formation through inhibiting NFATc1, Ca<sup>2+</sup> signalling and oxidative stress.

Published in:

Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 12, p. 8269, doi. 10.1111/jcmm.14700

By:

Chen, Xi;
Wang, Chao;
Qiu, Heng;
Yuan, Yu;
Chen, Kai;
Cao, Zhen;
Xiang Tan, Ren;
Tickner, Jennifer;
Xu, Jiake;
Zou, Jun

Publication type:

Article

Evodiamine inhibits RANKL‐induced osteoclastogenesis and prevents ovariectomy‐induced bone loss in mice.

Published in:

Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 1, p. 522, doi. 10.1111/jcmm.13955

By:

Jin, Haiming;
Yao, Lingya;
Chen, Kai;
Liu, Yuhao;
Wang, Qingqing;
Wang, Ziyi;
Liu, Qian;
Cao, Zhen;
Kenny, Jacob;
Tickner, Jennifer;
Wang, Xiangyang;
Xu, Jiake

Publication type:

Article

Madecassoside inhibits estrogen deficiency‐induced osteoporosis by suppressing RANKL‐induced osteoclastogenesis.

Published in:

Journal of Cellular & Molecular Medicine, 2019, v. 23, n. 1, p. 380, doi. 10.1111/jcmm.13942

By:

Wang, Qingqing;
Yao, Lingya;
Xu, Ke;
Jin, Haiming;
Chen, Kai;
Wang, Ziyi;
Liu, Qian;
Cao, Zhen;
kenny, Jacob;
Liu, Yuhao;
Tickner, Jennifer;
Xu, Huazi;
Xu, Jiake

Publication type:

Article

Bajijiasu Abrogates Osteoclast Differentiation via the Suppression of RANKL Signaling Pathways through NF-κB and NFAT.

Published in:

International Journal of Molecular Sciences, 2017, v. 18, n. 1, p. 203, doi. 10.3390/ijms18010203

By:

Guoju Hong;
Lin Zhou;
Xuguang Shi;
Wei He;
Wang Haibin;
Qiushi Wei;
Peng Chen;
Longkai Qi;
Tickner, Jennifer;
Li Lin;
Jiake Xu

Publication type:

Article

Amyloid β Peptide Enhances RANKL-Induced Osteoclast Activation through NF-κB, ERK, and Calcium Oscillation Signaling.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 10, p. 1683, doi. 10.3390/ijms17101683

By:

Shangfu Li;
Bu Yang;
Teguh, Dian;
Lin Zhou;
Jiake Xu;
Rong, Limin

Publication type:

Article

Andrographolide Inhibits Ovariectomy-Induced Bone Loss via the Suppression of RANKL Signaling Pathways.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 27470, doi. 10.3390/ijms161126039

By:

Tao Wang;
Qian Liu;
Lin Zhou;
Jin Bo Yuan;
Xixi Lin;
Rong Zeng;
Xiaonan Liang;
Jinmin Zhao;
Jiake Xu

Publication type:

Article

Berberine Sulfate Attenuates Osteoclast Differentiation through RANKL Induced NF-κB and NFAT Pathways.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 27087, doi. 10.3390/ijms161125998

By:

Lin Zhou;
Fangming Song;
Qian Liu;
Mingli Yang;
Jinmin Zhao;
Renxiang Tan;
Jun Xu;
Ge Zhang;
Quinn, Julian M. W.;
Tickner, Jennifer;
Jiake Xu

Publication type:

Article

Natural Germacrane Sesquiterpenes Inhibit Osteoclast Formation, Bone Resorption, RANKL-Induced NF-κB Activation, and IκBα Degradation.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 11, p. 26599, doi. 10.3390/ijms161125972

By:

Shengnan Qin;
Estabelle Ang;
Libing Dai;
Xiaohong Yang;
Dongping Ye;
Honghui Chen;
Lin Zhou;
Mingli Yang;
Dian Teguh;
Renxiang Tan;
Jun Xu;
Tickner, Jennifer;
Pavlos, Nathan J.;
Jiake Xu

Publication type:

Article

Antibiotic and microplastic co-exposure: Effects on Daphnia magna and implications for ecological risk assessment.

Published in:

2025

By:

Pei, Mengyuan;
Fan, Jingyuan;
Zhang, Chenxi;
Xu, Jiake;
Yang, Yujian;
Wei, Haotian;
Zhang, Cheng;
Zhu, Lusheng;
Gao, Peng

Publication type:

Literature Review

Evaluation of N-phosphonium chitosan as a novel vaccine carrier for intramuscular immunization.

Published in:

Journal of Biomaterials Applications, 2017, v. 32, n. 5, p. 677, doi. 10.1177/0885328217735221

By:

Cai, Jianzhou;
Zhang, Wu;
Xu, Jiake;
Xue, Wei;
Liu, Zonghua

Publication type:

Article

Biocompatibility and cellular uptake mechanisms of poly(N-isopropylacrylamide) in different cells.

Published in:

Journal of Bioactive & Compatible Polymers, 2017, v. 32, n. 1, p. 17, doi. 10.1177/0883911516648969

By:

Guo, Zhong;
Li, Sha;
Wang, Changyong;
Xu, Jiake;
Kirk, Brett;
Wu, Jianping;
Liu, Zonghua;
Xue, Wei

Publication type:

Article

Systemic Administration of Fibroblast Growth Factor 21 Improves the Recovery of Spinal Cord Injury (SCI) in Rats and Attenuates SCI-Induced Autophagy.

Published in:

Frontiers in Pharmacology, 2021, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.628369

By:

Zhu, Sipin;
Ying, Yibo;
Ye, Lin;
Ying, Weiyang;
Ye, Jiahui;
Wu, Qiuji;
Chen, Min;
Zhu, Hui;
Li, Xiaoyang;
Dou, Haicheng;
Xu, Huazi;
Wang, Zhouguang;
Xu, Jiake

Publication type:

Article

Betulinic Acid Protects From Bone Loss in Ovariectomized Mice and Suppresses RANKL-Associated Osteoclastogenesis by Inhibiting the MAPK and NFATc1 Pathways.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.01025

By:

Wei, Jiyong;
Li, Yicheng;
Liu, Qian;
Lan, Yanni;
Wei, Chengming;
Tian, Kun;
Wu, Liwei;
Lin, Chunbo;
Xu, Jiake;
Zhao, Jinmin;
Yang, Yuan

Publication type:

Article

Asiatic Acid Inhibits OVX-Induced Osteoporosis and Osteoclastogenesis Via Regulating RANKL-Mediated NF-κb and Nfatc1 Signaling Pathways.

Published in:

Frontiers in Pharmacology, 2020, p. N.PAG, doi. 10.3389/fphar.2020.00331

By:

Hong, Guoju;
Zhou, Lin;
Han, Xiaorui;
Sun, Ping;
Chen, Zhenqiu;
He, Wei;
Tickner, Jennifer;
Chen, Leilei;
Shi, Xuguang;
Xu, Jiake

Publication type:

Article

Fumitremorgin C Attenuates Osteoclast Formation and Function via Suppressing RANKL-Induced Signaling Pathways.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00238

By:

Yuan, Yu;
Chen, Kai;
Chen, Xi;
Wang, Chao;
Qiu, Heng;
Cao, Zhen;
Song, Dezhi;
Sun, Youqiang;
Guo, Jianmin;
Tickner, Jennifer;
Xu, Jiake;
Zou, Jun

Publication type:

Article