Works matching AU Xu, Heping

Results: 113

Targeting translocator protein (18 kDa) (TSPO) dampens pro-inflammatory microglia reactivity in the retina and protects from degeneration.

Published in:

2015

By:

Scholz, Rebecca;
Caramoy, Albert;
Bhuckory, Mohajeet B.;
Rashid, Khalid;
Mei Chen;
Heping Xu;
Grimm, Christian;
Langmann, Thomas;
Chen, Mei;
Xu, Heping

Publication type:

journal article

Peripheral blood mononuclear cells from neovascular age-related macular degeneration patients produce higher levels of chemokines CCL2 (MCP-1) and CXCL8 (IL-8).

Published in:

2017

By:

Lechner, Judith;
Mei Chen;
Hogg, Ruth E.;
Toth, Levente;
Silvestri, Giuliana;
Chakravarthy, Usha;
Heping Xu;
Chen, Mei;
Xu, Heping

Publication type:

journal article

L-shaped association between the blood pressure response index and short-term mortality in intensive care patients with sepsis: An analysis based on the MIMIC-IV database.

Published in:

PLoS ONE, 2025, v. 20, n. 6, p. 1, doi. 10.1371/journal.pone.0325110

By:

Xu, Heping;
Mo, Ruiyong;
Liu, Yiqiao;
Niu, Huan;
Cai, Xiongwei;
He, Ping

Publication type:

Article

A case of Candida auris candidemia in Xiamen, China, and a comparative analysis of clinical isolates in China.

Published in:

Mycology: An International Journal on Fungal Biology, 2022, v. 13, n. 1, p. 68, doi. 10.1080/21501203.2021.1994479

By:

Bing, Jian;
Wang, Sijia;
Xu, Heping;
Fan, Shuru;
Du, Han;
Nobile, Clarissa J.;
Huang, Guanghua

Publication type:

Article

Molecular Mechanisms Underlying Age-Related Ocular Diseases.

Published in:

Oxidative Medicine & Cellular Longevity, 2018, p. 1, doi. 10.1155/2018/8476164

By:

Amadio, Marialaura;
Kaarniranta, Kai;
Xu, Heping;
Smedowski, Adrian;
Ferrington, Deborah A.

Publication type:

Article

Zinc Protects Oxidative Stress-Induced RPE Death by Reducing Mitochondrial Damage and Preventing Lysosome Rupture.

Published in:

Oxidative Medicine & Cellular Longevity, 2017, p. 1, doi. 10.1155/2017/6926485

By:

Rajapakse, Dinusha;
Curtis, Tim;
Chen, Mei;
Xu, Heping

Publication type:

Article

Preparation, characterization and properties of UV-curable waterborne polyurethane acrylate/SiO coating.

Published in:

Journal of Coatings Technology & Research, 2012, v. 9, n. 5, p. 503, doi. 10.1007/s11998-012-9397-7

By:

Qiu, Fengxian;
Xu, Heping;
Wang, Yingying;
Xu, Jicheng;
Yang, Dongya

Publication type:

Article

Single‐cell RNA sequencing study of retinal immune regulators identified CD47 and CD59a expression in photoreceptors—Implications in subretinal immune regulation.

Published in:

Journal of Neuroscience Research, 2020, v. 98, n. 7, p. 1498, doi. 10.1002/jnr.24618

By:

Liu, Jian;
Tang, Miao;
Harkin, Kevin;
Du, Xuan;
Luo, Chang;
Chen, Mei;
Xu, Heping

Publication type:

Article

Intraocular complement activation is related to retinal vascular and neuronal degeneration in myopic retinopathy.

Published in:

Frontiers in Cellular Neuroscience, 2023, p. 1, doi. 10.3389/fncel.2023.1187400

By:

Ling Zeng;
Xiaoning Li;
Wei Pan;
Yao Tang;
Ding Lin;
Min Wang;
Wang Cai;
Ruiling Zhu;
Jianbo Wan;
Linghua Huang;
Heping Xu;
Zhikuan Yang

Publication type:

Article

Immune Cells in Subretinal Wound Healing and Fibrosis.

Published in:

Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.916719

By:

Szczepan, Manon;
Llorián-Salvador, María;
Chen, Mei;
Xu, Heping

Publication type:

Article

Plasma level of lipocalin 2 is increased in neovascular age-related macular degeneration patients, particularly those with macular fibrosis.

Published in:

Immunity & Ageing, 2020, v. 17, n. 1, p. 1, doi. 10.1186/s12979-020-00205-w

By:

Chen, Mei;
Yang, Nan;
Lechner, Judith;
Toth, Levente;
Hogg, Ruth;
Silvestri, Giuliana;
Chakravarthy, Usha;
Xu, Heping

Publication type:

Article

Higher plasma levels of complement C3a, C4a and C5a increase the risk of subretinal fibrosis in neovascular age-related macular degeneration.

Published in:

Immunity & Ageing, 2016, v. 13, p. 1, doi. 10.1186/s12979-016-0060-5

By:

Lechner, Judith;
Mei Chen;
Hogg, Ruth E.;
Toth, Levente;
Silvestri, Giuliana;
Chakravarthy, Usha;
Heping Xu

Publication type:

Article

Subcutaneous phaeohyphomycosis caused by Hongkongmyces snookiorum in a kidney transplant patient: a case report.

Published in:

2020

By:

Linqiang, Deng;
Yiguo, Chen;
Heping, Xu;
Dongke, Chen;
Longhua, Hu;
Xiaomei, Gui;
Xia, Zou

Publication type:

journal article

Pseudocell Tracer—A method for inferring dynamic trajectories using scRNAseq and its application to B cells undergoing immunoglobulin class switch recombination.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 5, p. 1, doi. 10.1371/journal.pcbi.1008094

By:

Reiman, Derek;
Manakkat Vijay, Godhev Kumar;
Xu, Heping;
Sonin, Andrew;
Chen, Dianyu;
Salomonis, Nathan;
Singh, Harinder;
Khan, Aly A.

Publication type:

Article

Antagonising Wnt/β-catenin signalling ameliorates lens-capsulotomy-induced retinal degeneration in a mouse model of diabetes.

Published in:

Diabetologia, 2018, v. 61, n. 11, p. 2433, doi. 10.1007/s00125-018-4682-3

By:

Hombrebueno, Jose R.;
Ali, Imran H. A.;
Ma, Jian-xing;
Chen, Mei;
Xu, Heping

Publication type:

Article

Collectin-11 Is an Important Modulator of Retinal Pigment Epithelial Cell Phagocytosis and Cytokine Production.

Published in:

Journal of Innate Immunity, 2017, v. 9, n. 6, p. 529, doi. 10.1159/000478042

By:

Dong, Xia;
Wu, Weiju;
Ma, Liang;
Liu, Chengfei;
Bhuckory, Mohajeet B.;
Wang, Liping;
Nandrot, Emeline F.;
Xu, Heping;
Li, Ke;
Liu, Yizhi;
Zhou, Wuding

Publication type:

Article

Identification of a new isoform of the murine Sh2d1a gene and its functional implications.

Published in:

SCIENCE CHINA Life Sciences, 2014, v. 57, n. 1, p. 81, doi. 10.1007/s11427-013-4584-z

By:

Wu, LongYan;
Lu, PeiWen;
Ma, WeiWei;
Chu, CoCo;
Xu, HePing;
Qi, Hai

Publication type:

Article

Loss of Synaptic Connectivity, Particularly in Second Order Neurons Is a Key Feature of Diabetic Retinal Neuropathy in the Ins2Akita Mouse.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0097970

By:

Hombrebueno, Jose R.;
Chen, Mei;
Penalva, Rosana G.;
Xu, Heping

Publication type:

Article

RAGE Regulates Immune Cell Infiltration and Angiogenesis in Choroidal Neovascularization.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0089548

By:

Chen, Mei;
Glenn, Josephine V.;
Dasari, Shilpa;
McVicar, Carmel;
Ward, Michael;
Colhoun, Liza;
Quinn, Michael;
Bierhaus, Angelika;
Xu, Heping;
Stitt, Alan W.

Publication type:

Article

Myeloid Cells Expressing VEGF and Arginase-1 Following Uptake of Damaged Retinal Pigment Epithelium Suggests Potential Mechanism That Drives the Onset of Choroidal Angiogenesis in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0072935

By:

Liu, Jian;
Copland, David A.;
Horie, Shintaro;
Wu, Wei-Kang;
Chen, Mei;
Xu, Yunhe;
Paul Morgan, B.;
Mack, Matthias;
Xu, Heping;
Nicholson, Lindsay B.;
Dick, Andrew D.

Publication type:

Article

Age- and Light-Dependent Development of Localised Retinal Atrophy in CCL2−/−CX3CR1GFP/GFP Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0061381

By:

Chen, Mei;
Hombrebueno, Jose R.;
Luo, Chang;
Penalva, Rosana;
Zhao, Jiawu;
Colhoun, Liza;
Pandi, Sudha Pirya Soundara;
Forrester, John V.;
Xu, Heping

Publication type:

Article

Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration.

Published in:

PLoS ONE, 2011, v. 6, n. 11, p. 1, doi. 10.1371/journal.pone.0027433

By:

Xinhua Shu;
Luhmann, Ulrich F. O.;
Aleman, Tomas S.;
Barker, Susan E.;
Lennon, Alan;
Tulloch, Brian;
Mei Chen;
Heping Xu;
Jacobson, Samuel G.;
Ali, Robin;
Wright, Alan F.

Publication type:

Article

Dysregulation in Retinal Para-Inflammation and Age- Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice.

Published in:

PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022818

By:

Mei Chen;
Forrester, John V.;
Heping Xu

Publication type:

Article

Sustained intraocular vascular endothelial growth factor neutralisation does not affect retinal and choroidal vasculature in Ins2 Akita diabetic mice.

Published in:

Diabetes & Vascular Disease Research, 2019, v. 16, n. 5, p. 440, doi. 10.1177/1479164119843092

By:

Lechner, Judith;
Hombrebueno, Jose R;
Pedrini, Edoardo;
Chen, Mei;
Xu, Heping

Publication type:

Article

Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration.

Published in:

2020

By:

Little, Karis;
Llorián-Salvador, Maria;
Tang, Miao;
Du, Xuan;
Marry, Stephen;
Chen, Mei;
Xu, Heping

Publication type:

journal article

Higher phagocytic activity of thioglycollateelicited peritoneal macrophages is related to metabolic status of the cells.

Published in:

Journal of Inflammation, 2017, v. 14, p. 1, doi. 10.1186/s12950-017-0151-x

By:

Pavlou, Sofia;
Luxi Wang;
Heping Xu;
Mei Chen

Publication type:

Article

IL-33 attenuates the development of experimental autoimmune uveitis.

Published in:

European Journal of Immunology, 2014, v. 44, n. 11, p. 3320, doi. 10.1002/eji.201444671

By:

Barbour, Mark;
Allan, Debbie;
Xu, Heping;
Pei, Cheng;
Chen, Mei;
Niedbala, Wanda;
Fukada, Sandra Y.;
Besnard, Anne‐Galle;
Alves‐Filho, Jose C.;
Tong, Xiaoguang;
Forrester, John V.;
Liew, Foo Yew;
Jiang, Hui‐Rong

Publication type:

Article

The soluble isoform of CTLA-4 as a regulator of T-cell responses.

Published in:

European Journal of Immunology, 2013, v. 43, n. 5, p. 1274, doi. 10.1002/eji.201242529

By:

Ward, Frank J.;
Dahal, Lekh N.;
Wijesekera, Subadra K.;
Abdul‐Jawad, Sultan K.;
Kaewarpai, Taniya;
Xu, Heping;
Vickers, Mark A.;
Barker, Robert N.

Publication type:

Article

Inhibition of the alternative pathway of complement activation reduces inflammation in experimental autoimmune uveoretinitis.

Published in:

European Journal of Immunology, 2010, v. 40, n. 10, p. 2870, doi. 10.1002/eji.201040323

By:

Chen, Mei;
Muckersie, Elizabeth;
Luo, Chang;
Forrester, John V.;
Xu, Heping

Publication type:

Article

Natural killer cells promote neutrophil extracellular traps and restrain macular degeneration in mice.

Published in:

Science Translational Medicine, 2024, v. 16, n. 760, p. 1, doi. 10.1126/scitranslmed.adi6626

By:

Dong, Xue;
Song, Yinting;
Liu, Yuming;
Kou, Xuejing;
Yang, Tianjing;
Shi, Samuel X.;
He, Kai;
Li, Yiming;
Li, Ziqi;
Yao, Xueming;
Guo, Ju;
Cui, Bohao;
Wu, Ziru;
Lei, Yi;
Du, Mei;
Chen, Mei;
Xu, Heping;
Liu, Qiang;
Shi, Fu-Dong;
Wang, Xiaohong

Publication type:

Article

Acute Post-Cataract Endophthalmitis Due to Phialemoniopsis curvata: A Rare Case Report.

Published in:

2022

By:

Tang, Mengli;
Li, Jun;
Xia, Fengjun;
Min, Changhang;
Liu, Zhaojun;
Hu, Yongmei;
Wang, Haichen;
Xu, Heping;
Zou, Mingxiang

Publication type:

Case Study

A Cross-Sectional Study of Clostridium Difficile Infection in Inpatients with Antibiotic Associated Diarrhea.

Published in:

Clinical Laboratory, 2023, v. 69, n. 4, p. 700, doi. 10.7754/Clin.Lab.2022.220514

By:

Xiaobo Ma;
Zhimeng Li;
Yanqing Zheng;
Lili Fang;
Huimei Lin;
Heping Xu;
Guolin Hong

Publication type:

Article

Old age promotes retinal fibrosis in choroidal neovascularization through circulating fibrocytes and profibrotic macrophages.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02731-y

By:

Yi, Caijiao;
Liu, Jian;
Deng, Wen;
Luo, Chang;
Qi, Jinyan;
Chen, Mei;
Xu, Heping

Publication type:

Article

Genetic targeting or pharmacological inhibition of galectin-3 dampens microglia reactivity and delays retinal degeneration.

Published in:

2022

By:

Tabel, Mona;
Wolf, Anne;
Szczepan, Manon;
Xu, Heping;
Jägle, Herbert;
Moehle, Christoph;
Chen, Mei;
Langmann, Thomas

Publication type:

journal article

Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells.

Published in:

Journal of Neuroinflammation, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12974-022-02546-3

By:

Llorián-Salvador, María;
Byrne, Eimear M.;
Szczepan, Manon;
Little, Karis;
Chen, Mei;
Xu, Heping

Publication type:

Article

Complement activation contributes to subretinal fibrosis through the induction of epithelial-to-mesenchymal transition (EMT) in retinal pigment epithelial cells.

Published in:

2022

By:

Llorián-Salvador, María;
Byrne, Eimear M.;
Szczepan, Manon;
Little, Karis;
Chen, Mei;
Xu, Heping

Publication type:

journal article

Macrophage elastase (MMP12) critically contributes to the development of subretinal fibrosis.

Published in:

2022

By:

Yi, Caijiao;
Liu, Jian;
Deng, Wen;
Luo, Chang;
Qi, Jinyan;
Chen, Mei;
Xu, Heping

Publication type:

journal article

Associations between triglyceride-glucose body mass index and all-cause mortality in ICU patients with sepsis and acute heart failure.

Published in:

BMC Cardiovascular Disorders, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12872-025-04804-7

By:

Xu, Heping;
Xie, Jinyuan;
Niu, Huan;
Cai, Xiongwei;
He, Ping

Publication type:

Article

Effect of continuous nursing based on life network on anxiety state and quality of life of patients with coronary heart disease.

Published in:

Minerva Surgery, 2023, v. 78, n. 3, p. 341, doi. 10.23736/S2724-5691.21.09198-X

By:

Jinyuan XIE;
Yan XIA;
Shuai MAO;
Siyuan HUANG;
Heping XU

Publication type:

Article

Sustained intraocular VEGF neutralization results in retinal neurodegeneration in the Ins2Akita diabetic mouse.

Published in:

Scientific Reports, 2015, p. 18316, doi. 10.1038/srep18316

By:

Hombrebueno, Jose R.;
Ali, Imran HA.;
Xu, Heping;
Chen, Mei

Publication type:

Article

Alterations in Circulating Immune Cells in Neovascular Age-Related Macular Degeneration.

Published in:

Scientific Reports, 2015, p. 16754, doi. 10.1038/srep16754

By:

Lechner, Judith;
Chen, Mei;
Hogg, Ruth E.;
Toth, Levente;
Silvestri, Giuliana;
Chakravarthy, Usha;
Xu, Heping

Publication type:

Article

MALDI-TOF MS-Based Clustering and Antifungal Susceptibility Tests of Talaromyces marneffei Isolates from Fujian and Guangxi (China).

Published in:

Infection & Drug Resistance, 2022, v. 15, p. 3449, doi. 10.2147/IDR.S364439

By:

Fang, Lili;
Liu, Minxue;
Huang, Chunlan;
Ma, Xiaobo;
Zheng, Yanqing;
Wu, Wenjuan;
Guo, Jian;
Huang, Jiangshan;
Xu, Heping

Publication type:

Article

Wnt signaling in age-related macular degeneration: human macular tissue and mouse model.

Published in:

2015

By:

Jingsheng Tuo;
Yujuan Wang;
Rui Cheng;
Yichao Li;
Mei Chen;
Fangfang Qiu;
Haohua Qian;
Defen Shen;
Penalva, Rosana;
Heping Xu;
Jian-Xing Ma;
Chi-Chao Chan;
Tuo, Jingsheng;
Wang, Yujuan;
Cheng, Rui;
Li, Yichao;
Chen, Mei;
Qiu, Fangfang;
Qian, Haohua;
Shen, Defen

Publication type:

journal article

Wedelolactone Attenuates N-methyl-N-nitrosourea-Induced Retinal Neurodegeneration through Suppression of the AIM2/CASP11 Pathway.

Published in:

Biomedicines, 2022, v. 10, n. 2, p. 311, doi. 10.3390/biomedicines10020311

By:

Harkin, Kevin;
Augustine, Josy;
Stitt, Alan W.;
Xu, Heping;
Chen, Mei

Publication type:

Article

IL-17A Damages the Blood–Retinal Barrier through Activating the Janus Kinase 1 Pathway.

Published in:

Biomedicines, 2021, v. 9, n. 7, p. 831, doi. 10.3390/biomedicines9070831

By:

Byrne, Eimear M.;
Llorián-Salvador, María;
Tang, Miao;
Margariti, Andriana;
Chen, Mei;
Xu, Heping

Publication type:

Article

Oxidative Stress and Mitochondrial Damage in Dry Age-Related Macular Degeneration Like NFE2L2/PGC-1α -/- Mouse Model Evoke Complement Component C5a Independent of C3.

Published in:

Biology (2079-7737), 2021, v. 10, n. 7, p. 622, doi. 10.3390/biology10070622

By:

Sridevi Gurubaran, Iswariyaraja;
Heloterä, Hanna;
Marry, Stephen;
Koskela, Ali;
Hyttinen, Juha M. T.;
Paterno, Jussi J.;
Urtti, Arto;
Chen, Mei;
Xu, Heping;
Kauppinen, Anu;
Kaarniranta, Kai

Publication type:

Article

Treatment planning study of Volumetric Modulated Arc Therapy and three dimensional field-in-field techniques for left chest-wall cancers with regional lymph nodes.

Published in:

Reports of Practical Oncology & Radiotherapy, 2016, v. 21, n. 6, p. 517, doi. 10.1016/j.rpor.2016.07.005

By:

Xu, Heping;
Hatcher, Gillian

Publication type:

Article

Impact of body mass index on mortality outcomes in intensive care patients with Staphylococcus aureus sepsis: A retrospective analysis.

Published in:

PLoS ONE, 2024, v. 19, n. 8, p. 1, doi. 10.1371/journal.pone.0308471

By:

Xu, Heping;
Liu, Yiqiao;
Niu, Huan;
Wang, Hong;
Zhan, Feng

Publication type:

Article

Increased intraocular inflammation in retinal vein occlusion is independent of circulating immune mediators and is involved in retinal oedema.

Published in:

Frontiers in Neuroscience, 2023, p. 1, doi. 10.3389/fnins.2023.1186025

By:

Yufan Zhou;
Jinyan Qi;
Hengwei Liu;
Shengnan Liang;
Tingting Guo;
Juan Chen;
Wei Pan;
Huanhuan Tan;
Jie Wang;
Heping Xu;
Zhongping Chen

Publication type:

Article

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis.

Published in:

Molecular Neurodegeneration, 2019, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13024-019-0305-9

By:

Wang, Luxi;
Pavlou, Sofia;
Du, Xuan;
Bhuckory, Mohajeet;
Xu, Heping;
Chen, Mei

Publication type:

Article