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Huntingtin-associated protein 1 interacts with Ahi1 to regulate cerebellar and brainstem development in mice.
- Published in:
- 2008
- By:
- Publication type:
- journal article
The Expanding Clinical Universe of Polyglutamine Disease.
- Published in:
- Neuroscientist, 2019, v. 25, n. 5, p. 512, doi. 10.1177/1073858418822993
- By:
- Publication type:
- Article
Insights into White Matter Defect in Huntington's Disease.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 21, p. 3381, doi. 10.3390/cells11213381
- By:
- Publication type:
- Article
Genetically modified large animal models for investigating neurodegenerative diseases.
- Published in:
- Cell & Bioscience, 2021, v. 11, n. 1, p. 1, doi. 10.1186/s13578-021-00729-8
- By:
- Publication type:
- Article
HAP40 modulates mutant Huntingtin aggregation and toxicity in Huntington's disease mice.
- Published in:
- Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06716-4
- By:
- Publication type:
- Article
Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells.
- Published in:
- Cellular & Molecular Life Sciences, 2012, v. 69, n. 8, p. 1305, doi. 10.1007/s00018-011-0692-8
- By:
- Publication type:
- Article
Loss of Ahil Affects Early Development by Impairing BM88/Cendl-Mediated Neuronal Differentiation.
- Published in:
- Journal of Neuroscience, 2013, v. 33, n. 19, p. 8172, doi. 10.1523/JNEUROSCI.0119-13.2013
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- Publication type:
- Article
Differential Activities of the Ubiquitin-Proteasome System in Neurons versus Glia May Account for the Preferential Accumulation of Misfolded Proteins in Neurons.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 49, p. 13285, doi. 10.1523/JNEUROSCI.4393-08.2008
- By:
- Publication type:
- Article
Full-Length Human Mutant Huntingtin with a Stable Polyglutamine Repeat Can Elicit Progressive and Selective Neuropathogenesis in BACHD Mice.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 24, p. 6182, doi. 10.1523/JNEUROSCI.0857-08.2008
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- Publication type:
- Article
N-Terminal Mutant Huntingtin Associates with Mitochondria and Impairs Mitochondrial Trafficking.
- Published in:
- Journal of Neuroscience, 2008, v. 28, n. 11, p. 2783, doi. 10.1523/JNEUROSCI.0106-08.2008
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- Publication type:
- Article
Toughening Effect of Oxirane‐Tetrahydrofuran Polyether (PEOT) on Blended and Cross‐Linked Nitrocellulose.
- Published in:
- Propellants, Explosives, Pyrotechnics, 2022, v. 47, n. 6, p. 1, doi. 10.1002/prep.202100385
- By:
- Publication type:
- Article
Tauopathy promotes spinal cord-dependent production of toxic amyloid-beta in transgenic monkeys.
- Published in:
- Signal Transduction & Targeted Therapy, 2023, v. 8, n. 1, p. 1, doi. 10.1038/s41392-023-01601-6
- By:
- Publication type:
- Article
Suppression of neuropil aggregates and neurological symptoms by an intracellular antibody implicates the cytoplasmic toxicity of mutant huntingtin.
- Published in:
- Journal of Cell Biology, 2008, v. 181, n. 5, p. 803, doi. 10.1083/jcb.200710158
- By:
- Publication type:
- Article
Impaired ubiquitin--proteasome system activity in the synapses of Huntington's disease mice.
- Published in:
- Journal of Cell Biology, 2008, v. 180, n. 6, p. 1177, doi. 10.1083/jcb.200709080
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- Publication type:
- Article
Expression of mutant huntingtin in glial cells contributes to neuronal excitotoxicity.
- Published in:
- Journal of Cell Biology, 2005, v. 171, n. 6, p. 1001, doi. 10.1083/jcb.200508072
- By:
- Publication type:
- Article
Huntingtin forms toxic NH2-terminal fragment complexes that are promoted by the age-dependent decrease in proteasome activity.
- Published in:
- Journal of Cell Biology, 2003, v. 163, n. 1, p. 109, doi. 10.1083/jcb.200306038
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- Publication type:
- Article
Early Parkinson's disease symptoms in a-synuclein transgenic monkeys.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 8, p. 2308, doi. 10.1093/hmg/ddu748
- By:
- Publication type:
- Article
Aged monkey brains reveal the role of ubiquitin-conjugating enzyme UBE2N in the synaptosomal accumulation of mutant huntingtin.
- Published in:
- Human Molecular Genetics, 2015, v. 24, n. 5, p. 1350, doi. 10.1093/hmg/ddu544
- By:
- Publication type:
- Article
TDP-43 causes differential pathology in neuronal versus glial cells in the mouse brain.
- Published in:
- Human Molecular Genetics, 2014, v. 23, n. 10, p. 2678, doi. 10.1093/hmg/ddt662
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- Publication type:
- Article
Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation.
- Published in:
- Human Molecular Genetics, 2011, v. 20, n. 7, p. 1424, doi. 10.1093/hmg/ddr023
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- Publication type:
- Article
Expression of Huntington's disease protein results in apoptotic neurons in the brains of cloned transgenic pigs.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 20, p. 3983, doi. 10.1093/hmg/ddq313
- By:
- Publication type:
- Article
Inhibiting the ubiquitin–proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments.
- Published in:
- Human Molecular Genetics, 2010, v. 19, n. 12, p. 2445, doi. 10.1093/hmg/ddq127
- By:
- Publication type:
- Article
Transcriptional dysregulation of TrkA associates with neurodegeneration in spinocerebellar ataxia type 17.
- Published in:
- Human Molecular Genetics, 2009, v. 18, n. 21, p. 4141, doi. 10.1093/hmg/ddp363
- By:
- Publication type:
- Article
Accumulation of N-terminal mutant huntingtin in mouse and monkey models implicated as a pathogenic mechanism in Huntington's disease.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 17, p. 2738, doi. 10.1093/hmg/ddn175
- By:
- Publication type:
- Article
Huntingtin-associated protein-1 is a modifier of the age-at-onset of Huntington's disease.
- Published in:
- Human Molecular Genetics, 2008, v. 17, n. 8, p. 1137, doi. 10.1093/hmg/ddn003
- By:
- Publication type:
- Article
Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease.
- Published in:
- Human Molecular Genetics, 2005, v. 14, n. 20, p. 3065, doi. 10.1093/hmg/ddi340
- By:
- Publication type:
- Article
MANF regulates hypothalamic control of food intake and body weight.
- Published in:
- Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00750-x
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- Publication type:
- Article
New pathogenic insights from large animal models of neurodegenerative diseases.
- Published in:
- Protein & Cell, 2022, v. 13, n. 10, p. 707, doi. 10.1007/s13238-022-00912-8
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- Publication type:
- Article
Genetically modified rodent models of SCA17.
- Published in:
- Journal of Neuroscience Research, 2017, v. 95, n. 8, p. 1540, doi. 10.1002/jnr.23984
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- Publication type:
- Article
Huntington's Disease: Complex Pathogenesis and Therapeutic Strategies.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 7, p. 3845, doi. 10.3390/ijms25073845
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- Publication type:
- Article
Distinctive Patterns of 5-Methylcytosine and 5-Hydroxymethylcytosine in Schizophrenia.
- Published in:
- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 636, doi. 10.3390/ijms25010636
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- Publication type:
- Article
Emerging Roles for DNA 6mA and RNA m6A Methylation in Mammalian Genome.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13897, doi. 10.3390/ijms241813897
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- Publication type:
- Article
Huntingtin Interacting Proteins and Pathological Implications.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 17, p. 13060, doi. 10.3390/ijms241713060
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- Publication type:
- Article
Accumulation of Endogenous Mutant Huntingtin in Astrocytes Exacerbates Neuropathology of Huntington Disease in Mice.
- Published in:
- Molecular Neurobiology, 2021, v. 58, n. 10, p. 5112, doi. 10.1007/s12035-021-02451-5
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- Publication type:
- Article
Expression of AHI1 Rescues Amyloidogenic Pathology in Alzheimer's Disease Model Cells.
- Published in:
- Molecular Neurobiology, 2019, v. 56, n. 11, p. 7572, doi. 10.1007/s12035-019-1587-1
- By:
- Publication type:
- Article
HAP1 Is Required for Endocytosis and Signalling of BDNF and Its Receptors in Neurons.
- Published in:
- Molecular Neurobiology, 2018, v. 55, n. 3, p. 1815, doi. 10.1007/s12035-016-0379-0
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- Publication type:
- Article
The early cellular pathology of Huntington’s disease.
- Published in:
- Molecular Neurobiology, 1999, v. 20, n. 2/3, p. 111, doi. 10.1007/BF02742437
- By:
- Publication type:
- Article
Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains.
- Published in:
- Acta Neuropathologica, 2019, v. 137, n. 6, p. 919, doi. 10.1007/s00401-019-01979-0
- By:
- Publication type:
- Article
Towards a transgenic model of Huntington’s disease in a non-human primate.
- Published in:
- Nature, 2008, v. 453, n. 7197, p. 921, doi. 10.1038/nature06975
- By:
- Publication type:
- Article
Dynamic 5-Hydroxymethylcytosine Change: Implication for Aging of Non-Human Primate Brain.
- Published in:
- Epigenomes, 2022, v. 6, n. 4, p. 41, doi. 10.3390/epigenomes6040041
- By:
- Publication type:
- Article
Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurologicalphenotypes of Huntington¿s disease mice.
- Published in:
- Molecular Brain, 2010, v. 3, p. 33, doi. 10.1186/1756-6606-3-33
- By:
- Publication type:
- Article
Mutant Ahi1 Affects Retinal Axon Projection in Zebrafish via Toxic Gain of Function.
- Published in:
- Frontiers in Cellular Neuroscience, 2019, p. N.PAG, doi. 10.3389/fncel.2019.00081
- By:
- Publication type:
- Article
Piperine ameliorates SCA17 neuropathology by reducing ER stress.
- Published in:
- Molecular Neurodegeneration, 2018, v. 13, p. 1, doi. 10.1186/s13024-018-0236-x
- By:
- Publication type:
- Article
Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain.
- Published in:
- Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0036-5
- By:
- Publication type:
- Article
Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain.
- Published in:
- Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0036-5
- By:
- Publication type:
- Article
CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases.
- Published in:
- Molecular Neurodegeneration, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13024-015-0031-x
- By:
- Publication type:
- Article
Pathological cell-cell interactions are necessary for striatal pathogenesis in a conditional mouse model of Huntington's disease.
- Published in:
- Molecular Neurodegeneration, 2007, v. 2, p. 8, doi. 10.1186/1750-1326-2-8
- By:
- Publication type:
- Article
Multiple pathways contribute to the pathogenesis of Huntington disease.
- Published in:
- Molecular Neurodegeneration, 2006, v. 1, p. 19, doi. 10.1186/1750-1326-1-19
- By:
- Publication type:
- Article
Polyglutamine expansion of huntingtin impairs its nuclear export.
- Published in:
- Nature Genetics, 2005, v. 37, n. 2, p. 198, doi. 10.1038/ng1503
- By:
- Publication type:
- Article
Association of HAP1 Isoforms with a Unique Cytoplasmic Structure.
- Published in:
- Journal of Neurochemistry, 1998, v. 71, n. 5, p. 2178, doi. 10.1046/j.1471-4159.1998.71052178.x
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- Publication type:
- Article