Works by Xia, Menghang

Results: 94

Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo.

Published in:

Emerging Microbes & Infections, 2020, v. 9, n. 1, p. 2404, doi. 10.1080/22221751.2020.1838954

By:

Li, Zhong;
Lang, Yuekun;
Sakamuru, Srilatha;
Samrat, Subodh;
Trudeau, Nicole;
Kuo, Lili;
Rugenstein, Natasha;
Tharappel, Anil;
D'Brant, Lianna;
Koetzner, Cheri A.;
Hu, Saiyang;
Zhang, Jing;
Huang, Ruili;
Kramer, Laura D.;
Butler, David;
Xia, Menghang;
Li, Hongmin

Publication type:

Article

Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo.

Published in:

Emerging Microbes & Infections, 2020, v. 9, n. 1, p. 2404, doi. 10.1080/22221751.2020.1838954

By:

Zhong Li;
Yuekun Lang;
Sakamuru, Srilatha;
Samrat, Subodh;
Trudeau, Nicole;
Lili Kuo;
Rugenstein, Natasha;
Tharappel, Anil;
D'Brant, Lianna;
Koetzner, Cheri A.;
Saiyang Hu;
Jing Zhang;
Ruili Huang;
Kramer, Laura D.;
Butler, David;
Menghang Xia;
Hongmin Li

Publication type:

Article

High-Throughput Phenotypic Screening of Human Astrocytes to Identify Compounds That Protect Against Oxidative Stress.

Published in:

Stem Cells Translational Medicine, 2016, v. 5, n. 5, p. 613, doi. 10.5966/sctm.2015-0170

By:

THORNE, NATASHA;
MALIK, NASIR;
SHAH, SONIA;
ZHAO, JEAN;
CLASS, BRADLEY;
AGUISANDA, FRANCIS;
SOUTHALL, NOEL;
XIA, MENGHANG;
MCKEW, JOHN C.;
RAO, MAHENDRA;
WEI ZHENG

Publication type:

Article

ICRF193 potentiates the genotoxicity of etoposide.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03522-6

By:

Ooka, Masato;
Mitchell, Leah;
Zhao, Jinghua;
Hirota, Kouji;
Huang, Ruili;
Abe, Takuya;
Xia, Menghang

Publication type:

Article

Investigating blood–brain barrier penetration and neurotoxicity of natural products for central nervous system drug development.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-90888-2

By:

Kato, Rintaro;
Zhang, Li;
Kinatukara, Nivedita;
Huang, Ruili;
Asthana, Abhinav;
Weber, Claire;
Xia, Menghang;
Xu, Xin;
Shah, Pranav

Publication type:

Article

Quantitative High-Throughput Profiling of Environmental Chemicals and Drugs that Modulate Farnesoid X Receptor.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06437

By:

Chia-Wen Hsu;
Jinghua Zhao;
Ruili Huang;
Jui-Hua Hsieh;
Hamm, Jon;
Xiaoqing Chang;
Houck, Keith;
Menghang Xia

Publication type:

Article

Identification of human pregnane X receptor antagonists utilizing a high-throughput screening platform.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1448744

By:

Lynch, Caitlin;
Margolis, Ryan;
Niebler, Jacob;
Travers, Jameson;
Sakamuru, Srilatha;
Zhao, Tongan;
Klumpp-Thomas, Carleen;
Huang, Ruili;
Xia, Menghang

Publication type:

Article

Prediction of hERG Liability - Using SVM Classification, Bootstrapping and Jackknifing.

Published in:

Molecular Informatics, 2017, v. 36, n. 4, p. n/a, doi. 10.1002/minf.201600126

By:

Sun, Hongmao;
Huang, Ruili;
Xia, Menghang;
Shahane, Sampada;
Southall, Noel;
Wang, Yuhong

Publication type:

Article

Prediction of Cytochrome P450 Profiles of Environmental Chemicals with QSAR Models Built from Drug-Like Molecules.

Published in:

Molecular Informatics, 2012, v. 31, n. 11/12, p. 783, doi. 10.1002/minf.201200065

By:

Sun, Hongmao;
Veith, Henrike;
Xia, Menghang;
Austin, Christopher P.;
Tice, Raymond R.;
Huang, Ruili

Publication type:

Article

A gene expression biomarker for predictive toxicology to identify chemical modulators of NF-κB.

Published in:

PLoS ONE, 2022, v. 17, n. 2, p. 1, doi. 10.1371/journal.pone.0261854

By:

Korunes, Katharine L.;
Liu, Jie;
Huang, Ruili;
Xia, Menghang;
Houck, Keith A.;
Corton, J. Christopher

Publication type:

Article

Identification of Environmental Compounds That May Trigger Early Female Puberty by Activating Human GnRHR and KISS1R.

Published in:

Endocrinology, 2024, v. 165, n. 10, p. 1, doi. 10.1210/endocr/bqae103

By:

Yang, Shu;
Zhang, Li;
Khan, Kamal;
Travers, Jameson;
Huang, Ruili;
Jovanovic, Vukasin M;
Veeramachaneni, Rithvik;
Sakamuru, Srilatha;
Tristan, Carlos A;
Davis, Erica E;
Klumpp-Thomas, Carleen;
Witt, Kristine L;
Simeonov, Anton;
Shaw, Natalie D;
Xia, Menghang

Publication type:

Article

Identification of environmental chemicals that activate p53 signaling after in vitro metabolic activation.

Published in:

Archives of Toxicology, 2022, v. 96, n. 7, p. 1975, doi. 10.1007/s00204-022-03291-5

By:

Ooka, Masato;
Zhao, Jinghua;
Shah, Pranav;
Travers, Jameson;
Klumpp-Thomas, Carleen;
Xu, Xin;
Huang, Ruili;
Ferguson, Stephen;
Witt, Kristine L.;
Smith-Roe, Stephanie L.;
Simeonov, Anton;
Xia, Menghang

Publication type:

Article

Review of high-content screening applications in toxicology.

Published in:

Archives of Toxicology, 2019, v. 93, n. 12, p. 3387, doi. 10.1007/s00204-019-02593-5

By:

Li, Shuaizhang;
Xia, Menghang

Publication type:

Article

Author Correction: Pharmacological rescue in patient iPSC and mouse models with a rare DISC1 mutation.

Published in:

2021

By:

Kim, Nam-Shik;
Wen, Zhexing;
Liu, Jing;
Zhou, Ying;
Guo, Ziyuan;
Xu, Chongchong;
Lin, Yu-Ting;
Yoon, Ki-Jun;
Park, Junhyun;
Cho, Michelle;
Kim, Minji;
Wang, Xinyuan;
Yu, Huimei;
Sakamuru, Srilatha;
Christian, Kimberly M.;
Hsu, Kuei-sen;
Xia, Menghang;
Li, Weidong;
Ross, Christopher A.;
Margolis, Russell L.

Publication type:

Correction Notice

Correction: A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.

Published in:

2016

By:

Martinez, Natalia J.;
Rai, Ganesha;
Yasgar, Adam;
Lea, Wendy A.;
Sun, Hongmao;
Wang, Yuhong;
Luci, Diane K.;
Yang, Shyh-Ming;
Nishihara, Kana;
Takeda, Shunichi;
Mohiuddin, null;
Earnshaw, Irina;
Okada, Tetsuya;
Mori, Kazutoshi;
Wilson, Kelli;
Riggins, Gregory J.;
Xia, Menghang;
Grimaldi, Maurizio;
Jadhav, Ajit;
Maloney, David J.

Publication type:

Correction Notice

A High-Throughput Screen Identifies 2,9-Diazaspiro[5.5]Undecanes as Inducers of the Endoplasmic Reticulum Stress Response with Cytotoxic Activity in 3D Glioma Cell Models.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0161486

By:

Martinez, Natalia J.;
Rai, Ganesha;
Yasgar, Adam;
Lea, Wendy A.;
Sun, Hongmao;
Wang, Yuhong;
Luci, Diane K.;
Yang, Shyh-Ming;
Nishihara, Kana;
Takeda, Shunichi;
Sagor, Mohiuddin;
Earnshaw, Irina;
Okada, Tetsuya;
Mori, Kazutoshi;
Wilson, Kelli;
Riggins, Gregory J.;
Xia, Menghang;
Grimaldi, Maurizio;
Jadhav, Ajit;
Maloney, David J.

Publication type:

Article

Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the µ Opioid Receptor.

Published in:

International Journal of Molecular Sciences, 2023, v. 24, n. 8, p. 7042, doi. 10.3390/ijms24087042

By:

Li, Zoe;
Liu, Jie;
Dong, Fan;
Chang, Nancy;
Huang, Ruili;
Xia, Menghang;
Patterson, Tucker A.;
Hong, Huixiao

Publication type:

Article

Application of In Vitro Metabolism Activation in High-Throughput Screening.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 21, p. 8182, doi. 10.3390/ijms21218182

By:

Ooka, Masato;
Lynch, Caitlin;
Xia, Menghang

Publication type:

Article

Assessment of Compound Hepatotoxicity Using Human Plateable Cryopreserved Hepatocytes in a 1536-Well-Plate Format.

Published in:

Assay & Drug Development Technologies, 2012, v. 10, n. 1, p. 78, doi. 10.1089/adt.2010.0365

By:

Moeller, Timothy A.;
Shukla, Sunita J.;
Xia, Menghang

Publication type:

Article

Generation and Characterization of a Cell Line with Inducible Expression of Cav3.2 (T-Type) Channels.

Published in:

Assay & Drug Development Technologies, 2003, v. 1, n. 5, p. 637

By:

Menghang Xia;
John P. Imredy;
Vincent P. Santarelli;
Hongyu Annie Liang;
Cindra L. Condra;
Paul Bennett;
Kenneth S. Koblan;
Thomas M. Connolly

Publication type:

Article

Evaluation of CYP3A4 inhibition and hepatotoxicity using DMSO-treated human hepatoma HuH-7 cells.

Published in:

Cell Biology & Toxicology, 2015, v. 31, n. 4/5, p. 221, doi. 10.1007/s10565-015-9306-9

By:

Liu, Yitong;
Flynn, Thomas;
Xia, Menghang;
Wiesenfeld, Paddy;
Ferguson, Martine

Publication type:

Article

Drug Repositioning for Noonan and LEOPARD Syndromes by Integrating Transcriptomics With a Structure-Based Approach.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00927

By:

Zhu, Liyuan;
Roberts, Ruth;
Huang, Ruili;
Zhao, Jinghua;
Xia, Menghang;
Delavan, Brian;
Mikailov, Mike;
Tong, Weida;
Liu, Zhichao

Publication type:

Article

Paradigm Shift in Toxicity Testing and Modeling.

Published in:

AAPS Journal, 2012, v. 14, n. 3, p. 473, doi. 10.1208/s12248-012-9358-1

By:

Sun, Hongmao;
Xia, Menghang;
Austin, Christopher;
Huang, Ruili

Publication type:

Article

Correction: Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

Published in:

2017

By:

Hsieh, Jui-Hua;
Huang, Ruili;
Lin, Ja-An;
Sedykh, Alexander;
Zhao, Jinghua;
Tice, Raymond R.;
Paules, Richard S.;
Xia, Menghang;
Auerbach, Scott S.

Publication type:

Correction Notice

Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177902

By:

Hsieh, Jui-Hua;
Huang, Ruili;
Lin, Ja-An;
Sedykh, Alexander;
Zhao, Jinghua;
Tice, Raymond R.;
Paules, Richard S.;
Xia, Menghang;
Auerbach, Scott S.

Publication type:

Article

Identification of Novel Activators of Constitutive Androstane Receptor from FDA-Approved Drugs by Integrated Computational and Biological Approaches.

Published in:

Pharmaceutical Research, 2013, v. 30, n. 2, p. 489, doi. 10.1007/s11095-012-0895-1

By:

Lynch, Caitlin;
Pan, Yongmei;
Li, Linhao;
Ferguson, Stephen;
Xia, Menghang;
Swaan, Peter;
Wang, Hongbing

Publication type:

Article

Identification of repurposed small molecule drugs for chordoma therapy.

Published in:

Cancer Biology & Therapy, 2013, v. 14, n. 7, p. 1, doi. 10.4161/cbt.24596

By:

Menghang Xia;
Ruili Huang;
Sakamuru, Srilatha;
Alcorta, David;
Ming-Hsuang Cho;
Dae-Hee Lee;
Park, Deric M.;
Kelley, Michael J.;
Sommer, Josh;
Austin, Christopher P.

Publication type:

Article

Neuropeptide Signaling of Lymphocytes in Immunological Responses.

Published in:

International Archives of Allergy & Immunology, 1995, v. 107, n. 1-3, p. 202, doi. 10.1159/000236977

By:

Goetzl, Edward J.;
Xia, Menghang;
Ingram, David A.;
Kishiyama, Jeffrey L.;
Kaltreider, Benfer;
Byrd, Patricia K.;
Ichikawa, Sanae;
Sreedharan, Sunil P.

Publication type:

Article

Integrin-dependent role of human T cell matrix metalloproteinase activity in chemotaxis through a model basement membrane.

Published in:

Journal of Cellular Biochemistry, 1996, v. 61, n. 3, p. 452, doi. 10.1002/(SICI)1097-4644(19960601)61:3<452::AID-JCB12>3.0.CO;2-L

By:

Xia, Menghang;
Sreedharan, Sunil P.;
Dazin, Paul;
Damsky, Caroline H.;
Goetzl, Edward J.

Publication type:

Article

Assessment of the DNA damaging potential of environmental chemicals using a quantitative high-throughput screening approach to measure p53 activation.

Published in:

Environmental & Molecular Mutagenesis, 2017, v. 58, n. 7, p. 494, doi. 10.1002/em.22112

By:

Witt, Kristine L.;
Hsieh, Jui‐Hua;
Smith‐Roe, Stephanie L.;
Xia, Menghang;
Huang, Ruili;
Zhao, Jinghua;
Auerbach, Scott S.;
Hur, Junguk;
Tice, Raymond R.

Publication type:

Article

Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair-deficient chicken DT40 cell lines.

Published in:

Environmental & Molecular Mutagenesis, 2011, v. 52, n. 7, p. 547, doi. 10.1002/em.20656

By:

Yamamoto, Kimiyo N.;
Hirota, Kouji;
Kono, Koichi;
Takeda, Shunichi;
Sakamuru, Srilatha;
Xia, Menghang;
Huang, Ruili;
Austin, Christopher P.;
Witt, Kristine L.;
Tice, Raymond R.

Publication type:

Article

Why are most phospholipidosis inducers also hERG blockers?

Published in:

Archives of Toxicology, 2017, v. 91, n. 12, p. 3885, doi. 10.1007/s00204-017-1995-9

By:

Slavov, Svetoslav;
Stoyanova-Slavova, Iva;
Li, Shuaizhang;
Zhao, Jinghua;
Huang, Ruili;
Xia, Menghang;
Beger, Richard

Publication type:

Article

Identification of Modulators That Activate the Constitutive Androstane Receptor From the Tox21 10K Compound Library.

Published in:

Toxicological Sciences, 2019, v. 167, n. 1, p. 282, doi. 10.1093/toxsci/kfy242

By:

Lynch, Caitlin;
Mackowiak, Bryan;
Huang, Ruili;
Li, Linhao;
Heyward, Scott;
Sakamuru, Srilatha;
Wang, Hongbing;
Xia, Menghang

Publication type:

Article

Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space.

Published in:

Toxicological Sciences, 2016, v. 152, n. 2, p. 323, doi. 10.1093/toxsci/kfw092

By:

Judson, Richard;
Houck, Keith;
Martin, Matt;
Richard, Ann M.;
Knudsen, Thomas B.;
Shah, Imran;
Little, Stephen;
Wambaugh, John;
Setzer, R. Woodrow;
Kothya, Parth;
Jimmy Phuong;
Filer, Dayne;
Smith, Doris;
Reif, David;
Rotroff, Daniel;
Kleinstreuer, Nicole;
Sipes, Nisha;
Menghang Xia;
Ruili Huang;
Crofton, Kevin

Publication type:

Article

Integrated Model of Chemical Perturbations of a Biological Pathway Using 18 In Vitro High-Throughput Screening Assays for the Estrogen Receptor.

Published in:

Toxicological Sciences, 2015, v. 148, n. 1, p. 137, doi. 10.1093/toxsci/kfv168

By:

Judson, Richard S.;
Magpantay, Felicia Maria;
Chickarmane, Vijay;
Haskell, Cymra;
Tania, Nessy;
Taylor, Jean;
Xia, Menghang;
Huang, Ruili;
Rotroff, Daniel M.;
Filer, Dayne L.;
Houck, Keith A.;
Martin, Matthew T.;
Sipes, Nisha;
Richard, Ann M.;
Mansouri, Kamel;
Setzer, R. Woodrow;
Knudsen, Thomas B.;
Crofton, Kevin M.;
Thomas, Russell S.

Publication type:

Article

Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 446, doi. 10.1093/toxsci/kfv141

By:

Shiuan Chen;
Jui-Hua Hsieh;
Ruili Huang;
Srilatha Sakamuru;
Li-Yu Hsin;
Menghang Xia;
Shockley, Keith R.;
Auerbach, Scott;
Noriko Kanaya;
Hannah Lu;
Svoboda, Daniel;
Witt, Kristine L.;
Merrick, B. Alex;
Teng, Christina T.;
Tice, Raymond R.

Publication type:

Article

AroER Tri-Screen Is a Biologically Relevant Assay for Endocrine Disrupting Chemicals Modulating the Activity of Aromatase and/or the Estrogen Receptor.

Published in:

Toxicological Sciences, 2014, v. 139, n. 1, p. 198, doi. 10.1093/toxsci/kfu023

By:

Chen, Shiuan;
Zhou, Dujin;
Hsin, Li-Yu;
Kanaya, Noriko;
Wong, Cynthie;
Yip, Richard;
Sakamuru, Srilatha;
Xia, Menghang;
Yuan, Yate-Ching;
Witt, Kristine;
Teng, Christina

Publication type:

Article

Quantitative High-Throughput Screening for Chemical Toxicity in a Population-Based In Vitro Model.

Published in:

Toxicological Sciences, 2012, v. 126, n. 2, p. 578, doi. 10.1093/toxsci/kfs023

By:

Lock, Eric F.;
Abdo, Nour;
Huang, Ruili;
Xia, Menghang;
Kosyk, Oksana;
O’Shea, Shannon H.;
Zhou, Yi-Hui;
Sedykh, Alexander;
Tropsha, Alexander;
Austin, Christopher P.;
Tice, Raymond R.;
Wright, Fred A.;
Rusyn, Ivan

Publication type:

Article

Weighted Feature Significance: A Simple, Interpretable Model of Compound Toxicity Based on the Statistical Enrichment of Structural Features.

Published in:

Toxicological Sciences, 2009, v. 112, n. 2, p. 385, doi. 10.1093/toxsci/kfp231

By:

Huang, Ruili;
Southall, Noel;
Menghang Xia;
Ming-Hsuang Cho;
Jadhav, Ajit;
Nguyen, Dac-Trung;
Inglese, James;
Tice, Raymond R.;
Austin, Christopher P.

Publication type:

Article

Identification of Chemical Compounds that Induce HIF-1α Activity.

Published in:

Toxicological Sciences, 2009, v. 112, n. 1, p. 153, doi. 10.1093/toxsci/kfp123

By:

Xia, Menghang;
Huang, Ruili;
Yi Sun;
Semenza, Gregg L.;
Aldred, Shelley Force;
Witt, Kristine L.;
Inglese, James;
Tice, Raymond R.;
Austin, Christopher P.

Publication type:

Article

Fingerprinting Interactions between Proteins and Ligands for Facilitating Machine Learning in Drug Discovery.

Published in:

Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 72, doi. 10.3390/biom14010072

By:

Li, Zoe;
Huang, Ruili;
Xia, Menghang;
Patterson, Tucker A.;
Hong, Huixiao

Publication type:

Article

High-Throughput Chemical Screening and Structure-Based Models to Predict hERG Inhibition.

Published in:

Biology (2079-7737), 2022, v. 11, n. 2, p. 209, doi. 10.3390/biology11020209

By:

Krishna, Shagun;
Borrel, Alexandre;
Huang, Ruili;
Zhao, Jinghua;
Xia, Menghang;
Kleinstreuer, Nicole

Publication type:

Article

Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization.

Published in:

Nature Communications, 2016, v. 7, n. 1, p. 10425, doi. 10.1038/ncomms10425

By:

Huang, Ruili;
Xia, Menghang;
Sakamuru, Srilatha;
Zhao, Jinghua;
Shahane, Sampada A.;
Attene-Ramos, Matias;
Zhao, Tongan;
Austin, Christopher P.;
Simeonov, Anton

Publication type:

Article

Development and validation of CYP26A1 inhibition assay for high‐throughput screening.

Published in:

Biotechnology Journal, 2024, v. 19, n. 6, p. 1, doi. 10.1002/biot.202300659

By:

Sakamuru, Srilatha;
Ma, Dongping;
Pierro, Jocylin D.;
Baker, Nancy C.;
Kleinstreuer, Nicole;
Cali, James J.;
Knudsen, Thomas B.;
Xia, Menghang

Publication type:

Article

Performance of the BG1Luc ER TA Method in a qHTS Format.

Published in:

Altex, 2015, v. 32, n. 4, p. 287, doi. 10.14573/altex.1505121

By:

Ceger, Patricia;
Allen, David;
Huang, Ruili;
Menghang Xia;
Casey, Warren

Publication type:

Article

Perspectives on Validation of High-Throughput Assays Supporting 21<sup>st</sup> Century Toxicity Testing.

Published in:

Altex, 2013, v. 30, n. 1, p. 51, doi. 10.14573/altex.2013.1.051

By:

Judson, Richard;
Kavlock, Robert;
Martin, Matthew;
Reif, David;
Houck, Keith;
Knudsen, Thomas;
Richard, Ann;
Tice, Raymond R.;
Whelan, Maurice;
Menghang Xia;
Huang, Ruili;
Austin, Christopher;
Daston, George;
Hartung, Thomas;
Fowle III, John R.;
Wooge, William;
Tong, Weida;
Dix, David

Publication type:

Article

Profiling the Tox21 Chemical Collection for Acetylcholinesterase Inhibition.

Published in:

Environmental Health Perspectives, 2021, v. 129, n. 4, p. 047008-1, doi. 10.1289/EHP6993

By:

Shuaizhang Li;
Jinghua Zhao;
Ruili Huang;
Travers, Jameson;
Klumpp-Thomas, Carleen;
Wenbo Yu;
MacKerell Jr, Alexander D.;
Sakamuru, Srilatha;
Masato Ooka;
Fengtian Xue;
Sipes, Nisha S.;
Jui-Hua Hsieh;
Ryan, Kristen;
Simeonov, Anton;
Santillo, Michael F.;
Menghang Xia

Publication type:

Article

Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library.

Published in:

Environmental Health Perspectives, 2019, v. 127, n. 9, p. 1, doi. 10.1289/EHP5314

By:

Paul-Friedman, Katie;
Martin, Matt;
Crofton, Kevin M.;
Chia-Wen Hsu;
Sakamuru, Srilatha;
Jinghua Zhao;
Menghang Xia;
Ruili Huang;
Stavreva, Diana A.;
Soni, Vikas;
Varticovski, Lyuba;
Raziuddin, Razi;
Hager, Gordon L.;
Houck, Keith A.

Publication type:

Article

Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.

Published in:

Environmental Health Perspectives, 2018, v. 126, n. 7, p. 077010-1, doi. 10.1289/EHP2589

By:

Menghang Xia;
Ruili Huang;
Qiang Shi;
Boyd, Windy A.;
Jinghua Zhao;
Nuo Sun;
Rice, Julie R.;
Dunlap, Paul E.;
Hackstadt, Amber J.;
Bridge, Matt F.;
Smith, Marjolein V.;
Sheng Dai;
Wei Zheng;
Pei-Hsuan Chu;
Gerhold, David;
Witt, Kristine L.;
DeVito, Michael;
Freedman, Jonathan H.;
Austin, Christopher P.;
Houck, Keith A.

Publication type:

Article

Mechanism Profiling of Hepatotoxicity Caused by Oxidative Stress Using Antioxidant Response Element Reporter Gene Assay Models and Big Data.

Published in:

Environmental Health Perspectives, 2016, v. 124, n. 5, p. 634, doi. 10.1289/ehp.1509763

By:

Thai Kim, Marlene;
Ruili Huang;
Sedykh, Alexander;
Wenyi Wang;
Menghang Xia;
Hao Zhu

Publication type:

Article