Found: 23
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Activation of Bicyclic Nitro-drugs by a Novel Nitroreductase (NTR2) in Leishmania.
- Published in:
- PLoS Pathogens, 2016, v. 12, n. 11, p. 1, doi. 10.1371/journal.ppat.1005971
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- Publication type:
- Article
Antitrypanosomatid Pharmacomodulation at Position 3 of the 8‐Nitroquinolin‐2(1H)‐one Scaffold Using Palladium‐Catalysed Cross‐Coupling Reactions.
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- ChemMedChem, 2018, v. 13, n. 20, p. 2217, doi. 10.1002/cmdc.201800456
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- Publication type:
- Article
Homoserine and quorum-sensing acyl homoserine lactones as alternative sources of threonine: a potential role for homoserine kinase in insect-stage Trypanosoma brucei.
- Published in:
- Molecular Microbiology, 2015, v. 95, n. 1, p. 143, doi. 10.1111/mmi.12853
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- Article
Trypanosoma brucei ( UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
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- Molecular Microbiology, 2013, v. 90, n. 2, p. 443, doi. 10.1111/mmi.12376
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- Publication type:
- Article
Chemical, genetic and structural assessment of pyridoxal kinase as a drug target in the African trypanosome.
- Published in:
- Molecular Microbiology, 2012, v. 86, n. 1, p. 51, doi. 10.1111/j.1365-2958.2012.08189.x
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- Publication type:
- Article
Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods.
- Published in:
- Molecular Microbiology, 2009, v. 74, n. 3, p. 529, doi. 10.1111/j.1365-2958.2009.06761.x
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- Publication type:
- Article
Chemical and genetic validation of dihydrofolate reductase–thymidylate synthase as a drug target in African trypanosomes.
- Published in:
- Molecular Microbiology, 2008, v. 69, n. 2, p. 520, doi. 10.1111/j.1365-2958.2008.06305.x
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- Publication type:
- Article
Visceral Leishmaniasis and Arsenic: An Ancient Poison Contributing to Antimonial Treatment Failure in the Indian Subcontinent?
- Published in:
- PLoS Neglected Tropical Diseases, 2011, v. 5, n. 9, p. 1, doi. 10.1371/journal.pntd.0001227
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- Article
Visceral Leishmaniasis and Arsenic: An Ancient Poison Contributing to Antimonial Treatment Failure in the Indian Subcontinent?
- Published in:
- 2011
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- Publication type:
- Opinion
Biochemical and genetic characterization of Trypanosoma cruzi N-myristoyltransferase.
- Published in:
- Biochemical Journal, 2014, v. 459, n. 2, p. 323, doi. 10.1042/BJ20131033
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- Publication type:
- Article
The anti-tubercular drug delamanid as a potential oral treatment for visceral leishmaniasis.
- Published in:
- eLife, 2016, p. 1, doi. 10.7554/eLife.09744
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- Publication type:
- Article
Identification of Resistance Determinants for a Promising Antileishmanial Oxaborole Series.
- Published in:
- Microorganisms, 2021, v. 9, n. 7, p. 1408, doi. 10.3390/microorganisms9071408
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- Publication type:
- Article
The Anti-Trypanosome Drug Fexinidazole Shows Potential for Treating Visceral Leishmaniasis.
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- Science Translational Medicine, 2012, v. 4, n. 119, p. 1, doi. 10.1126/scitranslmed.3003326
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- Article
A comparative study of methylglyoxal metabolism in trypanosomatids.
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- FEBS Journal, 2009, v. 276, n. 2, p. 376, doi. 10.1111/j.1742-4658.2008.06788.x
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- Publication type:
- Article
ATP-dependent ligases in trypanothione biosynthesis – kinetics of catalysis and inhibition by phosphinic acid pseudopeptides.
- Published in:
- FEBS Journal, 2008, v. 275, n. 21, p. 5408, doi. 10.1111/j.1742-4658.2008.06670.x
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- Publication type:
- Article
Oligo targeting for profiling drug resistance mutations in the parasitic trypanosomatids.
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- Nucleic Acids Research, 2022, v. 50, n. 14, p. e79, doi. 10.1093/nar/gkac319
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- Publication type:
- Article
Live-imaging rate-of-kill compound profiling for Chagas disease drug discovery with a new automated high-content assay.
- Published in:
- PLoS Neglected Tropical Diseases, 2021, v. 15, n. 10, p. 1, doi. 10.1371/journal.pntd.0009870
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- Publication type:
- Article
Sterol 14-alpha demethylase (CYP51) activity in Leishmania donovani is likely dependent upon cytochrome P450 reductase 1.
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- PLoS Pathogens, 2024, v. 20, n. 7, p. 1, doi. 10.1371/journal.ppat.1012382
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- Publication type:
- Article
Pentacyclic nitrofurans that rapidly kill nifurtimox-resistant trypanosomes.
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- 2016
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- Publication type:
- journal article
Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei.
- Published in:
- 2016
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- Publication type:
- journal article
Mode of action studies confirm on-target engagement of lysyl-tRNA synthetase inhibitor and lead to new selection marker for Cryptosporidium.
- Published in:
- Frontiers in Cellular & Infection Microbiology, 2023, v. 13, p. 01, doi. 10.3389/fcimb.2023.1236814
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- Publication type:
- Article
Identifying regulators of transcription in an obligate intracellular pathogen: a metal-dependent repressor in Chlamydia trachomatis.
- Published in:
- Molecular Microbiology, 2001, v. 40, n. 4, p. 1027, doi. 10.1046/j.1365-2958.2001.02453.x
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- Publication type:
- Article
Synthesis of Nitrostyrylthiazolidine-2,4-dione Derivatives Displaying Antileishmanial Potential.
- Published in:
- Pharmaceuticals (14248247), 2024, v. 17, n. 7, p. 878, doi. 10.3390/ph17070878
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- Publication type:
- Article