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HIV-1 Vaccine-elicited Antibodies Reverted to Their Inferred Naive Germline Reveal Associations between Binding Affinity and in vivo Activation.
- Published in:
- Scientific Reports, 2016, p. 20987, doi. 10.1038/srep20987
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- Article
Primate immune responses to HIV-1 Env formulated in the saponin-based adjuvant AbISCO-100 in the presence or absence of TLR9 co-stimulation.
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- Scientific Reports, 2015, p. 8925, doi. 10.1038/srep08925
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- Article
Targeted N-glycan deletion at the receptor-binding site retains HIV Env NFL trimer integrity and accelerates the elicited antibody response.
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- PLoS Pathogens, 2017, v. 13, n. 9, p. 1, doi. 10.1371/journal.ppat.1006614
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- Article
mRNA lipid nanoparticles expressing cell-surface cleavage independent HIV Env trimers elicit autologous tier-2 neutralizing antibodies.
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- Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1426232
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- Article
Thermostability of Well-Ordered HIV Spikes Correlates with the Elicitation of Autologous Tier 2 Neutralizing Antibodies.
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- PLoS Pathogens, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.ppat.1005767
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- Article
Well-Ordered Trimeric HIV-1 Subtype B and C Soluble Spike Mimetics Generated by Negative Selection Display Native-like Properties.
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- PLoS Pathogens, 2015, v. 11, n. 1, p. 1, doi. 10.1371/journal.ppat.1004570
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- Article
HIV-1 Receptor Binding Site-Directed Antibodies Using a VH1-2 Gene Segment Orthologue Are Activated by Env Trimer Immunization.
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- PLoS Pathogens, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.ppat.1004337
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- Article
Structure-guided Alterations of the gp41-directed HIV-1 Broadly Neutralizing Antibody 2F5 Reveal New Properties Regarding its Neutralizing Function.
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- PLoS Pathogens, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.ppat.1002806
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- Article
The challenges of eliciting neutralizing antibodies to HIV-1 and to influenza virus.
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- Nature Reviews Microbiology, 2008, v. 6, n. 2, p. 143, doi. 10.1038/nrmicro1819
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- Article
Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals.
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- 2009
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- Publication type:
- Letter
Structure-Guided Redesign Improves NFL HIV Env Trimer Integrity and Identifies an Inter-Protomer Disulfide Permitting Post-Expression Cleavage.
- Published in:
- Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.01631
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- Article
Cleavage-Independent HIV-1 Trimers From CHO Cell Lines Elicit Robust Autologous Tier 2 Neutralizing Antibodies.
- Published in:
- Frontiers in Immunology, 2018, p. 1, doi. 10.3389/fimmu.2018.01116
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- Publication type:
- Article
Differential processing of HIV envelope glycans on the virus and soluble recombinant trimer.
- Published in:
- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-06121-4
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- Article
Structure of a cleavage-independent HIV Env recapitulates the glycoprotein architecture of the native cleaved trimer.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-04272-y
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- Publication type:
- Article
Heterologous Epitope-Scaffold Prime:Boosting Immuno- Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant.
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- PLoS ONE, 2011, v. 6, n. 1, p. 1, doi. 10.1371/journal.pone.0016074
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- Article
Broad and potent HIV-1 neutralization by a human antibody that binds the gp41-gp120 interface.
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- Nature, 2014, v. 515, n. 7525, p. 138, doi. 10.1038/nature13601
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- Article
High-Resolution Definition of Vaccine-Elicited B Cell Responses Against the HIV Primary Receptor Binding Site.
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- Science Translational Medicine, 2012, v. 4, n. 142, p. 1, doi. 10.1126/scitranslmed.3003752
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- Article
HIV vaccine design and the neutralizing antibody problem.
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- Nature Immunology, 2004, v. 5, n. 3, p. 233, doi. 10.1038/ni0304-233
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- Article
Antigen-Specific Single B Cell Sorting and Monoclonal Antibody Cloning in Guinea Pigs.
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- Frontiers in Microbiology, 2019, p. N.PAG, doi. 10.3389/fmicb.2019.00672
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- Publication type:
- Article
Glutaraldehyde Cross-linking of HIV-1 Env Trimers Skews the Antibody Subclass Response in Mice.
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- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01654
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- Publication type:
- Article
Fusion of the molecular adjuvant C3d to cleavage-independent native-like HIV-1 Env trimers improves the elicited antibody response.
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- Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1180959
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- Publication type:
- Article
Broad HIV-1 neutralization mediated by CD4-binding site antibodies.
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- Nature Medicine, 2007, v. 13, n. 9, p. 1032, doi. 10.1038/nm1624
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- Publication type:
- Article
Structurally related but genetically unrelated antibody lineages converge on an immunodominant HIV-1 Env neutralizing determinant following trimer immunization.
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- PLoS Pathogens, 2021, v. 17, n. 9, p. 1, doi. 10.1371/journal.ppat.1009543
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- Article
Evolution of B cell analysis and Env trimer redesign.
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- Immunological Reviews, 2017, v. 275, n. 1, p. 183, doi. 10.1111/imr.12515
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- Article
Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help.
- Published in:
- Nanomaterials (2079-4991), 2019, v. 9, n. 10, p. 1389, doi. 10.3390/nano9101389
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- Article
Design and Functional Characterization of HIV-1 Envelope Protein-Coupled T Helper Liposomes.
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- Pharmaceutics, 2022, v. 14, n. 7, p. N.PAG, doi. 10.3390/pharmaceutics14071385
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- Publication type:
- Article
Structure-Based Stabilization of HIV-1 gp120 Enhances Humoral Immune Responses to the Induced Co-Receptor Binding Site.
- Published in:
- PLoS Pathogens, 2009, v. 5, n. 5, p. 1, doi. 10.1371/journal.ppat.1000445
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- Publication type:
- Article
B Cell Recognition of the Conserved HIV-1 Co-Receptor Binding Site Is Altered by Endogenous Primate CD4.
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- PLoS Pathogens, 2008, v. 4, n. 10, p. 1, doi. 10.1371/journal.ppat.1000171
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- Article