Works by Woodward, Emma R.

Results: 38

SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity.

Published in:

Molecular Genetics & Genomic Medicine, 2017, v. 5, n. 3, p. 237, doi. 10.1002/mgg3.279

By:

Casey, Ruth T.;
Ascher, David B.;
Rattenberry, Eleanor;
Izatt, Louise;
Andrews, Katrina A.;
Simpson, Helen L.;
Challis, Benjamen;
Park, Soo‐Mi;
Bulusu, Venkata R.;
Lalloo, Fiona;
Pires, Douglas E. V.;
West, Hannah;
Clark, Graeme R.;
Smith, Philip S.;
Whitworth, James;
Papathomas, Thomas G.;
Taniere, Phillipe;
Savisaar, Rosina;
Hurst, Laurence D.;
Woodward, Emma R.

Publication type:

Article

Real-World Concordance between Germline and Tumour BRCA1/2 Status in Epithelial Ovarian Cancer.

Published in:

Cancers, 2024, v. 16, n. 1, p. 177, doi. 10.3390/cancers16010177

By:

Morgan, Robert D.;
Burghel, George J.;
Schlecht, Helene;
Clamp, Andrew R.;
Hasan, Jurjees;
Mitchell, Claire L.;
Salih, Zena;
Shaw, Joseph;
Desai, Sudha;
Jayson, Gordon C.;
Woodward, Emma R.;
Evans, D. Gareth R.

Publication type:

Article

Is Reflex Germline BRCA1/2 Testing Necessary in Women Diagnosed with Non-Mucinous High-Grade Epithelial Ovarian Cancer Aged 80 Years or Older?

Published in:

Cancers, 2023, v. 15, n. 3, p. 730, doi. 10.3390/cancers15030730

By:

Morgan, Robert D.;
Burghel, George J.;
Flaum, Nicola;
Bulman, Michael;
Smith, Philip;
Clamp, Andrew R.;
Hasan, Jurjees;
Mitchell, Claire L.;
Salih, Zena;
Woodward, Emma R.;
Lalloo, Fiona;
Crosbie, Emma J.;
Edmondson, Richard J.;
Schlecht, Helene;
Jayson, Gordon C.;
Evans, D. Gareth R.

Publication type:

Article

Gene Panel Testing for Breast Cancer Reveals Differential Effect of Prior BRCA1/2 Probability.

Published in:

Cancers, 2021, v. 13, n. 16, p. 4154, doi. 10.3390/cancers13164154

By:

Evans, D. Gareth;
van Veen, Elke M.;
Woodward, Emma R.;
Harkness, Elaine F.;
Ellingford, Jamie M.;
Bowers, Naomi L.;
Wallace, Andrew J.;
Howell, Sacha J.;
Howell, Anthony;
Lalloo, Fiona;
Newman, William G.;
Smith, Miriam J.

Publication type:

Article

Germline TP53 Testing in Breast Cancers: Why, When and How?

Published in:

Cancers, 2020, v. 12, n. 12, p. 3762, doi. 10.3390/cancers12123762

By:

Evans, D. Gareth;
Woodward, Emma R.;
Bajalica-Lagercrantz, Svetlana;
Oliveira, Carla;
Frebourg, Thierry

Publication type:

Article

Risk of Contralateral Breast Cancer in Women with and without Pathogenic Variants in BRCA1, BRCA2, and TP53 Genes in Women with Very Early-Onset (<36 Years) Breast Cancer.

Published in:

Cancers, 2020, v. 12, n. 2, p. 378, doi. 10.3390/cancers12020378

By:

Hyder, Zerin;
Harkness, Elaine F.;
Woodward, Emma R.;
Bowers, Naomi L.;
Pereira, Marta;
Wallace, Andrew J.;
Howell, Sacha J.;
Howell, Anthony;
Lalloo, Fiona;
Newman, William G.;
Smith, Miriam J.;
Evans, D Gareth

Publication type:

Article

FGFR genes mutation is an independent prognostic factor and associated with lymph node metastasis in squamous non-small cell lung cancer.

Published in:

Cancer Biology & Therapy, 2018, v. 19, n. 12, p. 1108, doi. 10.1080/15384047.2018.1480294

By:

Li, Jing Jing;
Yan, Shi;
Pan, Yaqi;
Liu, Zhen;
Liu, Ying;
Deng, Qiuju;
Tan, Qin;
Woodward, Emma R.;
Wu, Nan

Publication type:

Article

BRCA1/2 in non-mucinous epithelial ovarian cancer: tumour with or without germline testing?

Published in:

2022

By:

Morgan, Robert D.;
Burghel, George J.;
Flaum, Nicola;
Bulman, Michael;
Smith, Philip;
Clamp, Andrew R.;
Hasan, Jurjees;
Mitchell, Claire L.;
Salih, Zena;
Woodward, Emma R.;
Lalloo, Fiona;
Crosbie, Emma J.;
Edmondson, Richard J.;
Wallace, Andrew J.;
Jayson, Gordon C.;
Evans, D. Gareth R.

Publication type:

journal article

Cancer Precision-Prevention trial of Metformin in adults with Li Fraumeni syndrome (MILI) undergoing yearly MRI surveillance: a randomised controlled trial protocol.

Published in:

Trials, 2024, v. 25, n. 1, p. 1, doi. 10.1186/s13063-024-07929-w

By:

Dixon-Zegeye, Miriam;
Shaw, Rachel;
Collins, Linda;
Perez-Smith, Kendra;
Ooms, Alexander;
Qiao, Maggie;
Pantziarka, Pan;
Izatt, Louise;
Tischkowitz, Marc;
Harrison, Rachel E.;
George, Angela;
Woodward, Emma R.;
Lord, Simon;
Hawkes, Lara;
Evans, D. Gareth;
Franklin, James;
Hanson, Helen;
Blagden, Sarah P.

Publication type:

Article

Identification of BRCA1-deficient ovarian cancers.

Published in:

2011

By:

SKYTTE, ANNE-BINE;
WALDSTRØM, MARIANNE;
RASMUSSEN, ANDERS AAMANN;
CRÜGER, DORTHE;
WOODWARD, EMMA R.;
KØLVRAA, STEEN;
Waldstrøm, Marianne;
Crüger, Dorthe;
Kølvraa, Steen

Publication type:

journal article

Corrigendum: Contrasting effects on HIF-1α regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 9, p. 844, doi. 10.1093/hmg/ddab037

By:

Clifford, Steven C;
Cockman, Matthew E;
Smallwood, Alan C;
Mole, David R;
Woodward, Emma R;
Maxwell, Patrick H;
Ratcliffe, Peter J;
Maher, Eamonn R

Publication type:

Article

Germline SDHB Mutations and Familial Renal Cell Carcinoma.

Published in:

JNCI: Journal of the National Cancer Institute, 2008, v. 100, n. 17, p. 1260, doi. 10.1093/jnci/djn254

By:

Ricketts, Christopher;
Woodward, Emma R.;
Killick, Pip;
Morris, Mark R.;
Astuti, Dewi;
Latif, Farida;
Maher, Eamonn R.

Publication type:

Article

Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low levels.

Published in:

International Journal of Cancer, 2021, v. 148, n. 5, p. 1155, doi. 10.1002/ijc.33378

By:

Crosbie, Emma J.;
Flaum, Nicola;
Harkness, Elaine F.;
Clayton, Richard D.;
Holland, Cathrine;
Martin‐Hirsch, Pierre;
Wood, Nick;
Keating, Patrick;
Woodward, Emma R.;
Lalloo, Fiona;
Donnai, Paul;
Edmondson, Richard J.;
Evans, D. Gareth

Publication type:

Article

VHL mutation analysis in patients with isolated central nervous system haemangioblastoma.

Published in:

Brain: A Journal of Neurology, 2007, v. 130, n. 3, p. 836, doi. 10.1093/brain/awl362

By:

Emma R. Woodward;
Kerry Wall;
Joan Forsyth;
Fiona Macdonald;
Eamonn R. Maher

Publication type:

Article

Cascade screening in HBOC and Lynch syndrome: guidelines and procedures in a UK centre.

Published in:

Familial Cancer, 2024, v. 23, n. 2, p. 187, doi. 10.1007/s10689-024-00360-9

By:

Evans, D. Gareth;
Green, Kate;
Burghel, George J.;
Forde, Claire;
Lalloo, Fiona;
Schlecht, Helene;
Woodward, Emma R.

Publication type:

Article

Perspectives on the implications of carrying putative pathogenic variants in the medulloblastoma predisposition genes ELP1 and GPR161.

Published in:

2023

By:

Smith, Miriam J;
Woodward, Emma R;
Evans, D Gareth

Publication type:

Case Study

Extended gene panel testing in lobular breast cancer.

Published in:

Familial Cancer, 2022, v. 21, n. 2, p. 129, doi. 10.1007/s10689-021-00241-5

By:

van Veen, Elke M.;
Evans, D. Gareth;
Harkness, Elaine F.;
Byers, Helen J.;
Ellingford, Jamie M.;
Woodward, Emma R.;
Bowers, Naomi L.;
Wallace, Andrew J.;
Howell, Sacha J.;
Howell, Anthony;
Lalloo, Fiona;
Newman, William G.;
Smith, Miriam J.

Publication type:

Article

New surveillance guidelines for Li-Fraumeni and hereditary TP53 related cancer syndrome: implications for germline TP53 testing in breast cancer.

Published in:

2021

By:

Evans, D. Gareth;
Woodward, Emma R.

Publication type:

Editorial

Concern regarding classification of germline TP53 variants as likely pathogenic.

Published in:

Human Mutation, 2019, v. 40, n. 6, p. 828, doi. 10.1002/humu.23750

By:

Evans, D. Gareth;
Turnbull, Clare;
Woodward, Emma R.

Publication type:

Article

UBE2 QL1 is Disrupted by a Constitutional Translocation Associated with Renal Tumor Predisposition and is a Novel Candidate Renal Tumor Suppressor Gene.

Published in:

Human Mutation, 2013, v. 34, n. 12, p. 1650, doi. 10.1002/humu.22433

By:

Wake, Naomi C.;
Ricketts, Christopher J.;
Morris, Mark R.;
Prigmore, Elena;
Gribble, Susan M.;
Skytte, Anne‐Bine;
Brown, Michael;
Clarke, Noel;
Banks, Rosamonde E.;
Hodgson, Shirley;
Turnell, Andrew S.;
Maher, Eamonn R.;
Woodward, Emma R.

Publication type:

Article

Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD.

Published in:

Human Mutation, 2010, v. 31, n. 1, p. 41, doi. 10.1002/humu.21136

By:

Ricketts, Christopher J.;
Forman, Julia R.;
Rattenberry, Eleanor;
Bradshaw, Nicola;
Lalloo, Fiona;
Izatt, Louise;
Cole, Trevor R.;
Armstrong, Ruth;
Kumar, V.K. Ajith;
Morrison, Patrick J.;
Atkinson, A. Brew;
Douglas, Fiona;
Ball, Steve G.;
Cook, Jackie;
Srirangalingam, Umasuthan;
Killick, Pip;
Kirby, Gail;
Aylwin, Simon;
Woodward, Emma R.;
Evans, D. Gareth R.

Publication type:

Article

Genotype-phenotype correlations in von Hippel-Lindau disease.

Published in:

Human Mutation, 2007, v. 28, n. 2, p. 143, doi. 10.1002/humu.20385

By:

Ong, Kai Ren;
Woodward, Emma R.;
Killick, Pip;
Lim, Caron;
Macdonald, Fiona;
Maher, Eamonn R.

Publication type:

Article

Pathogenic germline variants in patients with features of hereditary renal cell carcinoma: Evidence for further locus heterogeneity.

Published in:

Genes, Chromosomes & Cancer, 2021, v. 60, n. 1, p. 5, doi. 10.1002/gcc.22893

By:

Smith, Philip S.;
West, Hannah;
Whitworth, James;
Castle, Bruce;
Sansbury, Francis H.;
Warren, Anne Y.;
Woodward, Emma R.;
Tischkowitz, Marc;
Maher, Eamonn R.

Publication type:

Article

Characterization of renal cell carcinoma‐associated constitutional chromosome abnormalities by genome sequencing.

Published in:

Genes, Chromosomes & Cancer, 2020, v. 59, n. 6, p. 333, doi. 10.1002/gcc.22833

By:

Smith, Philip S.;
Whitworth, James;
West, Hannah;
Cook, Jacqueline;
Gardiner, Carol;
Lim, Derek H. K.;
Morrison, Patrick J.;
Hislop, R. Gordon;
Murray, Emily;
Tischkowitz, Marc;
Warren, Anne Y.;
Woodward, Emma R.;
Maher, Eamonn R.

Publication type:

Article

Postpartum Breast Cancer and Survival in Women With Germline BRCA Pathogenic Variants.

Published in:

JAMA Network Open, 2024, v. 7, n. 4, p. e247421, doi. 10.1001/jamanetworkopen.2024.7421

By:

Zhang, Zhenzhen;
Ye, Shangyuan;
Bernhardt, Sarah M.;
Nelson, Heidi D.;
Velie, Ellen M.;
Borges, Virginia F.;
Woodward, Emma R.;
Evans, D. Gareth R.;
Schedin, Pepper J.

Publication type:

Article

Population-based survey of cancer risks in chromosome 3 translocation carriers.

Published in:

Genes, Chromosomes & Cancer, 2010, v. 49, n. 1, p. 52, doi. 10.1002/gcc.20718

By:

Woodward, Emma R.;
Skytte, Anne-Bine;
Cruger, Dorthe G.;
Maher, Eamonn R.

Publication type:

Article

Genome-wide CpG island methylation analysis implicates novel genes in the pathogenesis of renal cell carcinoma.

Published in:

Epigenetics, 2012, v. 7, n. 3, p. 278, doi. 10.4161/epi.7.3.19103

By:

Ricketts, Christopher J.;
Morris, Mark R.;
Gentle, Dean;
Brown, Michael;
Wake, Naomi;
Woodward, Emma R.;
Clarke, Noel;
Latif, Farida;
Maher, Eamonn R.

Publication type:

Article

Rapid reversal of clinical down‐classification of a BRCA1 splicing variant avoiding psychological harm.

Published in:

Clinical Genetics, 2019, v. 95, n. 4, p. 532, doi. 10.1111/cge.13488

By:

Burghel, George J.;
Banks, Catherine;
Wallace, Andrew J.;
Smith, Miriam J.;
Woodward, Emma R.;
Evans, D. Gareth;
Morgan, Robert D.;
Turnbull, Clare

Publication type:

Article

Genetic Predisposition to Phaeochromocytoma: Analysis of Candidate Genes GDNF, RET and VHL.

Published in:

Human Molecular Genetics, 1997, v. 6, n. 7, p. 1051, doi. 10.1093/hmg/6.7.1051

By:

Woodward, Emma R.;
Eng, Charis;
McMahon, Rob;
Voutilainen, Raimo;
Affara, Nabeel A.;
Ponder, Bruce A. J.;
Maher, Eamonn R.

Publication type:

Article

Fanconi Anaemia, Childhood Cancer and the BRCA Genes.

Published in:

Genes, 2021, v. 12, n. 10, p. 1520, doi. 10.3390/genes12101520

By:

Woodward, Emma R.;
Meyer, Stefan

Publication type:

Article

Investigation and Management of Apparently Sporadic Central Nervous System Haemangioblastoma for Evidence of Von Hippel–Lindau Disease.

Published in:

Genes, 2021, v. 12, n. 9, p. 1414, doi. 10.3390/genes12091414

By:

Furness, Hugh;
Salfity, Louay;
Devereux, Johanna;
Halliday, Dorothy;
Hanson, Helen;
Ruddy, Deborah M.;
Shah, Neha;
Sultana, George;
Woodward, Emma R.;
Sandford, Richard N.;
Snape, Katie M.;
Maher, Eamonn R.

Publication type:

Article

Profiling of Somatic Mutations in Phaeochromocytoma and Paraganglioma by Targeted Next Generation Sequencing Analysis.

Published in:

International Journal of Endocrinology, 2015, v. 2015, p. 1, doi. 10.1155/2015/138573

By:

Luchetti, Andrea;
Walsh, Diana;
Rodger, Fay;
Clark, Graeme;
Martin, Tom;
Irving, Richard;
Sanna, Mario;
Yao, Masahiro;
Robledo, Mercedes;
Neumann, Hartmut P. H.;
Woodward, Emma R.;
Latif, Farida;
Abbs, Stephen;
Martin, Howard;
Maher, Eamonn R.

Publication type:

Article

Germline FH mutations presenting with pheochromocytoma.

Published in:

2014

By:

Clark, Graeme R;
Sciacovelli, Marco;
Gaude, Edoardo;
Walsh, Diana M;
Kirby, Gail;
Simpson, Michael A;
Trembath, Richard C;
Berg, Jonathan N;
Woodward, Emma R;
Kinning, Esther;
Morrison, Patrick J;
Frezza, Christian;
Maher, Eamonn R

Publication type:

journal article

A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma.

Published in:

2013

By:

Rattenberry, Eleanor;
Vialard, Lindsey;
Yeung, Anna;
Bair, Hayley;
McKay, Kirsten;
Jafri, Mariam;
Canham, Natalie;
Cole, Trevor R;
Denes, Judit;
Hodgson, Shirley V;
Irving, Richard;
Izatt, Louise;
Korbonits, Márta;
Kumar, Ajith V;
Lalloo, Fiona;
Morrison, Patrick J;
Woodward, Emma R;
Macdonald, Fiona;
Wallis, Yvonne;
Maher, Eamonn R

Publication type:

journal article

Breast cancer incidence and early diagnosis in a family history risk and prevention clinic: 33-year experience in 14,311 women.

Published in:

Breast Cancer Research & Treatment, 2021, v. 189, n. 3, p. 677, doi. 10.1007/s10549-021-06333-1

By:

Evans, D. Gareth;
Howell, Sacha J.;
Gandhi, Ashu;
van Veen, Elke M.;
Woodward, Emma R.;
Harvey, James;
Barr, Lester;
Wallace, Andrew;
Lalloo, Fiona;
Wilson, Mary;
Hurley, Emma;
Lim, Yit;
Maxwell, Anthony J.;
Harkness, Elaine F.;
Howell, Anthony

Publication type:

Article

RE: Heterozygous BRCA1/BRCA2 and mismatch repair gene pathogenic variants in children and adolescents with cancer.

Published in:

JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 2, p. 224, doi. 10.1093/jnci/djac223

By:

Evans, D Gareth;
Woodward, Emma R

Publication type:

Article

Cancer risks by sex and variant type in PTEN hamartoma tumor syndrome.

Published in:

JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 1, p. 93, doi. 10.1093/jnci/djac188

By:

Hendricks, Linda A J;
Hoogerbrugge, Nicoline;
Mensenkamp, Arjen R;
Brunet, Joan;
Lleuger-Pujol, Roser;
Høberg-Vetti, Hildegunn;
Haavind, Marianne Tveit;
Innella, Giovanni;
Turchetti, Daniela;
Aretz, Stefan;
Spier, Isabel;
Tischkowitz, Marc;
Jahn, Arne;
Links, Thera P;
Olderode-Berends, Maran J W;
Blatnik, Ana;
Leter, Edward M;
Evans, D Gareth;
Woodward, Emma R;
Steinke-Lange, Verena

Publication type:

Article

From BRCA1 to Polygenic Risk Scores: Mutation-Associated Risks in Breast Cancer-Related Genes.

Published in:

Breast Care, 2021, v. 16, n. 3, p. 202, doi. 10.1159/000515319

By:

Woodward, Emma R.;
van Veen, Elke M.;
Evans, D. Gareth

Publication type:

Article