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Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.
Published in:
eLife, 2020, p. 1, doi. 10.7554/eLife.5641
By:
- Alghamdi, Ali H.;
- Munday, Jane C.;
- Campagnaro, Gustavo Daniel;
- Gurvic, Dominik;
- Svensson, Fredrik;
- Okpara, Chinyere E.;
- Kumar, Arvind;
- Quintana, Juan;
- Abril, Maria Esther Martin;
- Milić, Patrik;
- Watson, Laura;
- Paape, Daniel;
- Settimo, Luca;
- Dimitriou, Anna;
- Wielinska, Joanna;
- Smart, Graeme;
- Anderson, Laura F.;
- Woodley, Christopher M.;
- Siu Pui Ying Kelly;
- Ibrahim, Hasan M. S.
Publication type:
Article
Artemisinin inspired synthetic endoperoxide drug candidates: Design, synthesis, and mechanism of action studies.
Published in:
Medicinal Research Reviews, 2021, v. 41, n. 6, p. 3062, doi. 10.1002/med.21849
By:
- Woodley, Christopher M.;
- Amado, Patrícia S. M.;
- Cristiano, Maria L. S.;
- O'Neill, Paul M.
Publication type:
Article
Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1331224
By:
- Albulescu, Laura-Oana;
- Westhorpe, Adam;
- Clare, Rachel H.;
- Woodley, Christopher M.;
- James, Nivya;
- Kool, Jeroen;
- Berry, Neil G.;
- O'Neill, Paul M.;
- Casewell, Nicholas R.
Publication type:
Article
Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors.
Published in:
Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2023.1328950
By:
- Clare, Rachel H.;
- Dawson, Charlotte A.;
- Westhorpe, Adam;
- Albulescu, Laura-Oana;
- Woodley, Christopher M.;
- Mosallam, Nada;
- Chong, Daniel J. W.;
- Kool, Jeroen;
- Berry, Neil G.;
- O'Neill, Paul M.;
- Casewell, Nicholas R.
Publication type:
Article

Found: 4

Positively selected modifications in the pore of TbAQP2 allow pentamidine to enter Trypanosoma brucei.

Artemisinin inspired synthetic endoperoxide drug candidates: Design, synthesis, and mechanism of action studies.

Optimizing drug discovery for snakebite envenoming via a high-throughput phospholipase A2 screening platform.

Snakebite drug discovery: high-throughput screening to identify novel snake venom metalloproteinase toxin inhibitors.