Works matching AU Wood, Andrew R.

Results: 82

Rare variant associations with birth weight identify genes involved in adipose tissue regulation, placental function and insulin-like growth factor signalling.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-024-55761-2

By:

Kentistou, Katherine A.;
Lim, Brandon E. M.;
Kaisinger, Lena R.;
Steinthorsdottir, Valgerdur;
Sharp, Luke N.;
Patel, Kashyap A.;
Tragante, Vinicius;
Hawkes, Gareth;
Gardner, Eugene J.;
Olafsdottir, Thorhildur;
Wood, Andrew R.;
Zhao, Yajie;
Thorleifsson, Gudmar;
Day, Felix R.;
Ozanne, Susan E.;
Hattersley, Andrew T.;
O'Rahilly, Stephen;
Stefansson, Kari;
Ong, Ken K.;
Beaumont, Robin N.

Publication type:

Article

Evidence of a causal relationship between body mass index and psoriasis: a Mendelian randomization study.

Published in:

Norsk Epidemiologi, 2018, v. 28, n. Supplement 1, p. 25

By:

Budu-Aggrey, Ashley;
Brumpton, Ben;
Tyrrell, Jess;
Watkins, Sarah;
Modalsli, Ellen H.;
Celis-Morales, Carlos;
Ferguson, Lyn D.;
Vie, Gunnhild Å.;
Palmer, Tom;
Fritsche, Lars G.;
Løset, Mari;
Nielsen, Jonas Bille;
Wei Zhou;
Tsoi, Lam C.;
Wood, Andrew R.;
Jones, Samuel E.;
Beaumont, Robin;
Saunes, Marit;
Romundstad, Pål R.;
Siebert, Stefan

Publication type:

Article

Effects of physical activity and sedentary time on depression, anxiety and well-being: a bidirectional Mendelian randomisation study.

Published in:

BMC Medicine, 2023, v. 21, n. 1, p. 1, doi. 10.1186/s12916-023-03211-z

By:

Casanova, Francesco;
O'Loughlin, Jessica;
Karageorgiou, Vasilis;
Beaumont, Robin N.;
Bowden, Jack;
Wood, Andrew R.;
Tyrrell, Jessica

Publication type:

Article

Unclassified endogenous eczema.

Published in:

Contact Dermatitis (01051873), 1999, v. 41, n. 1, p. 18, doi. 10.1111/j.1600-0536.1999.tb06202.x

By:

MacKenzie-Wood, Andrew R.;
Freeman, Susanne

Publication type:

Article

A single nucleotide polymorphism genetic risk score to aid diagnosis of coeliac disease: a pilot study in clinical care.

Published in:

Alimentary Pharmacology & Therapeutics, 2020, v. 52, n. 7, p. 1165, doi. 10.1111/apt.15826

By:

Sharp, Seth A.;
Jones, Samuel E.;
Kimmitt, Robert A.;
Weedon, Michael N.;
Halpin, Anne M.;
Wood, Andrew R.;
Beaumont, Robin N.;
King, Seema;
Heel, David A.;
Campbell, Patricia M.;
Hagopian, William A.;
Turner, Justine M.;
Oram, Richard A

Publication type:

Article

Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25805-y

By:

Porcu, Eleonora;
Sadler, Marie C.;
Lepik, Kaido;
Auwerx, Chiara;
Wood, Andrew R.;
Weihs, Antoine;
Sleiman, Maroun S. Bou;
Ribeiro, Diogo M.;
Bandinelli, Stefania;
Tanaka, Toshiko;
Nauck, Matthias;
Völker, Uwe;
Delaneau, Olivier;
Metspalu, Andres;
Teumer, Alexander;
Frayling, Timothy;
Santoni, Federico A.;
Reymond, Alexandre;
Kutalik, Zoltán

Publication type:

Article

Methods for quick, accurate and cost-effective determination of the type 1 diabetes genetic risk score (T1D-GRS).

Published in:

Clinical Chemistry & Laboratory Medicine, 2020, v. 58, n. 4, p. e102, doi. 10.1515/cclm-2019-0787

By:

Locke, Jonathan M.;
Latten, Mark J.;
Datta, Renu Y.;
Wood, Andrew R.;
Crockard, Martin A.;
Lamont, John V.;
Weedon, Michael N.;
Oram, Richard A.

Publication type:

Article

Omics-squared: human genomic, transcriptomic and phenotypic data for genetic analysis workshop 19.

Published in:

BMC Proceedings, 2016, v. 10, p. 71, doi. 10.1186/s12919-016-0008-y

By:

Blangero, John;
Teslovich, Tanya M.;
Xueling Sim;
Almeida, Marcio A.;
Goo Jun;
Dyer, Thomas D.;
Johnson, Matthew;
Peralta, Juan M.;
Manning, Alisa;
Wood, Andrew R.;
Fuchsberger, Christian;
Kent Jr, Jack W.;
Aguilar, David A.;
Below, Jennifer E.;
Farook, Vidya S.;
Arya, Rector;
Fowler, Sharon;
Blackwell, Tom W.;
Puppala, Sobha;
Kumar, Satish

Publication type:

Article

Assessing the Causal Role of Sleep Traits on Glycated Hemoglobin: A Mendelian Randomization Study.

Published in:

2022

By:

Junxi Liu;
Richmond, Rebecca C.;
Bowden, Jack;
Barry, Ciarrah;
Dashti, Hassan S.;
Daghlas, Iyas;
Lane, Jacqueline M.;
Jones, Samuel E.;
Wood, Andrew R.;
Frayling, Timothy M.;
Wright, Alison K.;
Carr, Matthew J.;
Anderson, Simon G.;
Emsley, Richard A.;
Ray, David W.;
Weedon, Michael N.;
Saxena, Richa;
Lawlor, Deborah A.;
Rutter, Martin K.;
Liu, Junxi

Publication type:

journal article

Development and Standardization of an Improved Type 1 Diabetes Genetic Risk Score for Use in Newborn Screening and Incident Diagnosis.

Published in:

2019

By:

Sharp, Seth A.;
Rich, Stephen S.;
Wood, Andrew R.;
Jones, Samuel E.;
Beaumont, Robin N.;
Harrison, James W.;
Schneider, Darius A.;
Locke, Jonathan M.;
Tyrrell, Jess;
Weedon, Michael N.;
Hagopian, William A.;
Oram, Richard A.

Publication type:

journal article

Multiple Loci Are Associated with White Blood Cell Phenotypes.

Published in:

PLoS Genetics, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.pgen.1002113

By:

Nalls, Michael A.;
Couper, David J.;
Tanaka, Toshiko;
van Rooij, Frank J. A.;
Ming-Huei Chen;
Smith, Albert V.;
Toniolo, Daniela;
Zakai, Neil A.;
Qiong Yang;
Greinacher, Andreas;
Wood, Andrew R.;
Garcia, Melissa;
Gasparini, Paolo;
Yongmei Liu;
Lumley, Thomas;
Folsom, Aaron R.;
Reiner, Alex P.;
Gieger, Christian;
Lagou, Vasiliki;
Felix, Janine F.

Publication type:

Article

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts.

Published in:

PLoS Medicine, 2013, v. 10, n. 2, p. 1, doi. 10.1371/journal.pmed.1001383

By:

Vimaleswaran, Karani S.;
Berry, Diane J.;
Lu, Chen;
Tikkanen, Emmi;
Pilz, Stefan;
Hiraki, Linda T.;
Cooper, Jason D.;
Dastani, Zari;
Li, Rui;
Houston, Denise K.;
Wood, Andrew R.;
Michaëlsson, Karl;
Vandenput, Liesbeth;
Zgaga, Lina;
Yerges-Armstrong, Laura M.;
McCarthy, Mark I.;
Dupuis, Josée;
Kaakinen, Marika;
Kleber, Marcus E.;
Jameson, Karen

Publication type:

Article

Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile.

Published in:

Diabetic Medicine, 2021, v. 38, n. 9, p. 1, doi. 10.1111/dme.14531

By:

Heald, Adrian H.;
Martin, Susan;
Fachim, Helene;
Green, Harry D.;
Young, Katherine G.;
Malipatil, Nagaraj;
Siddals, Kirk;
Cortes, Gabriela;
Tyrrell, Jessica;
Wood, Andrew R;
Beaumont, Robin N.;
Frayling, Timothy M.;
Donn, Rachelle;
Narayanan, Ram Prakash;
Ollier, William;
Gibson, Martin;
Yaghootkar, Hanieh

Publication type:

Article

Genetically proxied therapeutic prolyl-hydroxylase inhibition and cardiovascular risk.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 3, p. 496, doi. 10.1093/hmg/ddac215

By:

Harlow, Charli E;
Patel, Vickas V;
Waterworth, Dawn M;
Wood, Andrew R;
Beaumont, Robin N;
Ruth, Katherine S;
Tyrrell, Jessica;
Oguro-Ando, Asami;
Chu, Audrey Y;
Frayling, Timothy M

Publication type:

Article

Fetal alleles predisposing to metabolically favorable adiposity are associated with higher birth weight.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 11, p. 1762, doi. 10.1093/hmg/ddab356

By:

Thompson, William D;
Beaumont, Robin N;
Kuang, Alan;
Warrington, Nicole M;
Ji, Yingjie;
Tyrrell, Jessica;
Wood, Andrew R;
Scholtens, Denise M;
Knight, Bridget A;
Evans, David M;
Jr, William L Lowe;
Santorelli, Gillian;
Azad, Raq;
Mason, Dan;
Hattersley, Andrew T;
Frayling, Timothy M;
Yaghootkar, Hanieh;
Borges, Maria Carolina;
Lawlor, Deborah A;
Freathy, Rachel M

Publication type:

Article

Corrigendum to: A genome-wide association study implicates multiple mechanisms influencing raised urinary albumin–creatinine ratio.

Published in:

Human Molecular Genetics, 2022, v. 31, n. 9, p. 1544, doi. 10.1093/hmg/ddac022

By:

Casanova, Francesco;
Tyrrell, Jessica;
Beaumont, Robin N;
Ji, Yingjie;
Jones, Samuel E;
Hattersley, Andrew T;
Weedon, Michael N;
Murray, Anna;
Shore, Angela C;
Frayling, Timothy M;
Wood, Andrew R

Publication type:

Article

Higher adiposity and mental health: causal inference using Mendelian randomization.

Published in:

Human Molecular Genetics, 2021, v. 30, n. 24, p. 2371, doi. 10.1093/hmg/ddab204

By:

Casanova, Francesco;
O’Loughlin, Jessica;
Martin, Susan;
Beaumont, Robin N.;
Wood, Andrew R.;
Watkins, Edward R.;
Freathy, Rachel M.;
Hagenaars, Saskia P.;
Frayling, Timothy M.;
Yaghootkar, Hanieh;
Tyrrell, Jess

Publication type:

Article

Insights into the genetics of menopausal vasomotor symptoms: genome-wide analyses of routinely-collected primary care health records.

Published in:

BMC Medical Genomics, 2023, v. 16, n. 1, p. 1, doi. 10.1186/s12920-023-01658-w

By:

Ruth, Katherine S.;
Beaumont, Robin N.;
Locke, Jonathan M.;
Tyrrell, Jessica;
Crandall, Carolyn J.;
Hawkes, Gareth;
Frayling, Timothy M.;
Prague, Julia K.;
Patel, Kashyap A.;
Wood, Andrew R.;
Weedon, Michael N.;
Murray, Anna

Publication type:

Article

Defining the role of common variation in the genomic and biological architecture of adult human height.

Published in:

Nature Genetics, 2014, v. 46, n. 11, p. 1173, doi. 10.1038/ng.3097

By:

Wood, Andrew R;
Pasko, Dorota;
Weedon, Michael N;
Frayling, Timothy M;
Kutalik, Zoltán;
Hassinen, Maija;
Hayward, Caroline;
Wright, Alan F;
Heard-Costa, Nancy L;
Helmer, Quinta;
Hillege, Hans L;
Hlatky, Mark A;
Assimes, Themistocles L;
Quertermous, Thomas;
Hoffmann, Wolfgang;
Völzke, Henry;
Hoffmann, Per;
Holmen, Oddgeir;
Hveem, Kristian;
Houwing-Duistermaat, Jeanine J

Publication type:

Article

A 3D Renal Proximal Tubule on Chip Model Phenocopies Lowe Syndrome and Dent II Disease Tubulopathy.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 10, p. 5361, doi. 10.3390/ijms22105361

By:

Naik, Sindhu;
Wood, Andrew R.;
Ongenaert, Maté;
Saidiyan, Paniz;
Elstak, Edo D.;
Lanz, Henriëtte L.;
Stallen, Jan;
Janssen, Richard;
Smythe, Elizabeth;
Erdmann, Kai S.;
Tonevitsky, Alexander;
Juuti-Uusitalo, Kati;
Viiri, Keijo

Publication type:

Article

Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisation.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.72452

By:

Martin, Susan;
Tyrrell, Jessica;
Thomas, E. Louise;
Bown, Matthew J.;
Wood, Andrew R.;
Beaumont, Robin N.;
Tsoi, Lam C.;
Stuart, Philip E.;
Elder, James T.;
Law, Philip;
Houlston, Richard;
Kabrhel, Christopher;
Papadimitriou, Nikos;
Gunter, Marc J.;
Bull, Caroline J.;
Bell, Joshua A.;
Vincent, Emma E.;
Sattar, Naveed;
Dunlop, Malcolm G.;
Tomlinson, Ian P. M.

Publication type:

Article

Hyperglycaemia is a causal risk factor for upper limb pathologies.

Published in:

International Journal of Epidemiology, 2024, v. 53, n. 1, p. 1, doi. 10.1093/ije/dyad187

By:

Green, Harry D;
Burden, Ella;
Chen, Ji;
Evans, Jonathan;
Patel, Kashyap;
Wood, Andrew R;
Beaumont, Robin N;
Tyrrell, Jessica;
Frayling, Timothy M;
Hattersley, Andrew T;
Oram, Richard A;
Bowden, Jack;
Barroso, Inês;
Smith, Christopher;
Weedon, Michael N

Publication type:

Article

Simulated distributions from negative experiments highlight the importance of the body mass index distribution in explaining depression-body mass index genetic risk score interactions.

Published in:

2022

By:

Casanova, Francesco;
O'Loughlin, Jessica;
Lewis, Cathryn;
Frayling, Timothy M;
Wood, Andrew R;
Tyrrell, Jessica

Publication type:

journal article

Effects of body mass index on relationship status, social contact and socio-economic position: Mendelian randomization and within-sibling study in UK Biobank.

Published in:

2020

By:

Howe, Laura D;
Kanayalal, Roshni;
Harrison, Sean;
Beaumont, Robin N;
Davies, Alisha R;
Frayling, Timothy M;
Davies, Neil M;
Hughes, Amanda;
Jones, Samuel E;
Sassi, Franco;
Wood, Andrew R;
Tyrrell, Jessica

Publication type:

journal article

Genetic evidence that higher central adiposity causes gastro-oesophageal reflux disease: a Mendelian randomization study.

Published in:

2020

By:

Green, Harry D;
Beaumont, Robin N;
Wood, Andrew R;
Hamilton, Benjamin;
Jones, Samuel E;
Goodhand, James R;
Kennedy, Nicholas A;
Ahmad, Tariq;
Yaghootkar, Hanieh;
Weedon, Michael N;
Frayling, Timothy M;
Tyrrell, Jessica

Publication type:

journal article

Using genetics to understand the causal influence of higher BMI on depression.

Published in:

2019

By:

Tyrrell, Jessica;
Mulugeta, Anwar;
Wood, Andrew R;
Zhou, Ang;
Beaumont, Robin N;
Tuke, Marcus A;
Jones, Samuel E;
Ruth, Katherine S;
Yaghootkar, Hanieh;
Sharp, Seth;
Thompson, William D;
Ji, Yingjie;
Harrison, Jamie;
Freathy, Rachel M;
Murray, Anna;
Weedon, Michael N;
Lewis, Cathryn;
Frayling, Timothy M;
Hyppönen, Elina

Publication type:

journal article

Gene-obesogenic environment interactions in the UK Biobank study.

Published in:

2017

By:

Tyrrell, Jessica;
Wood, Andrew R.;
Ames, Ryan M.;
Yaghootkar, Hanieh;
Beaumont, Robin N.;
Jones, Samuel E.;
Tuke, Marcus A.;
Ruth, Katherine S.;
Freathy, Rachel M.;
Smith, George Davey;
Joost, Stéphane;
Guessous, Idris;
Murray, Anna;
Strachan, David P.;
Kutalik, Zolt_n;
Weedon, Michael N.;
Frayling, Timothy M.;
Davey Smith, George;
Kutalik, Zoltán

Publication type:

journal article

Mendelian randomization study of height and risk of colorectal cancer.

Published in:

International Journal of Epidemiology, 2015, v. 44, n. 2, p. 662, doi. 10.1093/ije/dyv082

By:

Thrift, Aaron P.;
Jian Gong;
Peters, Ulrike;
Chang-Claude, Jenny;
Rudolph, Anja;
Slattery, Martha L.;
Chan, Andrew T.;
Esko, Tonu;
Wood, Andrew R.;
Jian Yang;
Vedantam, Sailaja;
Gustafsson, Stefan;
Pers, Tune H.;
Baron, John A.;
Bezieau, Stéphane;
Küry, Sébastien;
Ogino, Shuji;
Berndt, Sonja I.;
Casey, Graham;
Haile, Robert W.

Publication type:

Article

Red blood cell distribution width: Genetic evidence for aging pathways in 116,666 volunteers.

Published in:

PLoS ONE, 2017, v. 12, n. 9, p. 1, doi. 10.1371/journal.pone.0185083

By:

Pilling, Luke C.;
Atkins, Janice L.;
Duff, Michael O.;
Beaumont, Robin N.;
Jones, Samuel E.;
Tyrrell, Jessica;
Kuo, Chia-Ling;
Ruth, Katherine S.;
Tuke, Marcus A.;
Yaghootkar, Hanieh;
Wood, Andrew R.;
Murray, Anna;
Weedon, Michael N.;
Harries, Lorna W.;
Kuchel, George A.;
Ferrucci, Luigi;
Frayling, Timothy M.;
Melzer, David

Publication type:

Article

Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci.

Published in:

PLoS Genetics, 2016, v. 12, n. 8, p. 1, doi. 10.1371/journal.pgen.1006125

By:

Jones, Samuel E.;
Tyrrell, Jessica;
Wood, Andrew R.;
Beaumont, Robin N.;
Ruth, Katherine S.;
Tuke, Marcus A.;
Yaghootkar, Hanieh;
Hu, Youna;
Teder-Laving, Maris;
Hayward, Caroline;
Roenneberg, Till;
Wilson, James F.;
Del Greco, Fabiola;
Hicks, Andrew A.;
Shin, Chol;
Yun, Chang-Ho;
Lee, Seung Ku;
Metspalu, Andres;
Byrne, Enda M.;
Gehrman, Philip R.

Publication type:

Article

The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts.

Published in:

BMC Genomics, 2013, v. 14, n. 1, p. 1, doi. 10.1186/1471-2164-14-627

By:

Morrison, Faer S.;
Locke, Jonathan M.;
Wood, Andrew R.;
Tuke, Marcus;
Pasko, Dorota;
Murray, Anna;
Frayling, Tim;
Harries, Lorna W.

Publication type:

Article

Higher maternal adiposity reduces offspring birthweight if associated with a metabolically favourable profile.

Published in:

Diabetologia, 2021, v. 64, n. 12, p. 2790, doi. 10.1007/s00125-021-05570-9

By:

Thompson, William D.;
Beaumont, Robin N.;
Kuang, Alan;
Warrington, Nicole M.;
Ji, Yingjie;
Tyrrell, Jessica;
Wood, Andrew R.;
Scholtens, Denise M.;
Knight, Bridget A.;
Evans, David M.;
Lowe Jr, William L.;
Santorelli, Gillian;
Azad, Rafaq;
Mason, Dan;
Hattersley, Andrew T.;
Frayling, Timothy M.;
Yaghootkar, Hanieh;
Borges, Maria Carolina;
Lawlor, Deborah A.;
Freathy, Rachel M.

Publication type:

Article

Does physical activity moderate the association between shorter leukocyte telomere length and incident coronary heart disease? Data from 54,180 UK Biobank participants.

Published in:

GeroScience, 2024, v. 46, n. 1, p. 1331, doi. 10.1007/s11357-023-00890-7

By:

Xiang, Meiruo;
Pilling, Luke C.;
Melzer, David;
Kirk, Ben;
Duque, Gustavo;
Liu, Rui;
Kuchel, George A.;
Wood, Andrew R.;
Metcalf, Brad;
Diniz, Breno S.;
Hillsdon, Melvyn;
Kuo, Chia-Ling

Publication type:

Article

Influence of cell distribution and diabetes status on the association between mitochondrial DNA copy number and aging phenotypes in the InCHIANTI study.

Published in:

Aging Cell, 2018, v. 17, n. 1, p. 1, doi. 10.1111/acel.12683

By:

Moore, Ann Zenobia;
Ding, Jun;
Tuke, Marcus A.;
Wood, Andrew R.;
Bandinelli, Stefania;
Frayling, Timothy M.;
Ferrucci, Luigi

Publication type:

Article

Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.

Published in:

Aging Cell, 2011, v. 10, n. 5, p. 868, doi. 10.1111/j.1474-9726.2011.00726.x

By:

Harries, Lorna W.;
Hernandez, Dena;
Henley, William;
Wood, Andrew R.;
Holly, Alice C.;
Bradley-Smith, Rachel M.;
Yaghootkar, Hanieh;
Dutta, Ambarish;
Murray, Anna;
Frayling, Timothy M.;
Guralnik, Jack M.;
Bandinelli, Stefania;
Singleton, Andrew;
Ferrucci, Luigi;
Melzer, David

Publication type:

Article

Pyogenic granuloma-like lesions in a patient using topical tretinoin.

Published in:

Australasian Journal of Dermatology, 1998, v. 39, n. 4, p. 248, doi. 10.1111/j.1440-0960.1998.tb01483.x

By:

MacKenzie-Wood, Andrew R.;
Wood, Glenda

Publication type:

Article

Melanoma: Accuracy of clinical diagnosis.

Published in:

Australasian Journal of Dermatology, 1998, v. 39, n. 1, p. 31, doi. 10.1111/j.1440-0960.1998.tb01238.x

By:

MacKenzie-Wood, Andrew R.;
Milton, Gerry W.;
de Launey, John W.

Publication type:

Article

Severe allergy to sorbolene cream.

Published in:

Australasian Journal of Dermatology, 1997, v. 38, n. 1, p. 33, doi. 10.1111/j.1440-0960.1997.tb01096.x

By:

MacKenzie-Wood, Andrew R.;
Freeman, Susanne

Publication type:

Article

Office radiotherapy in dermatology: A contemporary perspective.

Published in:

Australasian Journal of Dermatology, 1996, v. 37, n. 2, p. 71, doi. 10.1111/j.1440-0960.1996.tb01009.x

By:

de Launey, John W.;
MacKenzie-Wood, Andrew R.

Publication type:

Article

Prosaposin is a regulator of progranulin levels and oligomerization.

Published in:

Nature Communications, 2016, v. 7, n. 6, p. 11992, doi. 10.1038/ncomms11992

By:

Nicholson, Alexandra M.;
Finch, NiCole A.;
Almeida, Marcio;
Perkerson, Ralph B.;
van Blitterswijk, Marka;
Wojtas, Aleksandra;
Cenik, Basar;
Rotondo, Sergio;
Inskeep, Venette;
Almasy, Laura;
Dyer, Thomas;
Peralta, Juan;
Jun, Goo;
Wood, Andrew R.;
Frayling, Timothy M.;
Fuchsberger, Christian;
Fowler, Sharon;
Teslovich, Tanya M.;
Manning, Alisa K.;
Kumar, Satish

Publication type:

Article

Biological interpretation of genome-wide association studies using predicted gene functions.

Published in:

Nature Communications, 2015, v. 6, n. 1, p. 5890, doi. 10.1038/ncomms6890

By:

Pers, Tune H.;
Karjalainen, Juha M.;
Chan, Yingleong;
Westra, Harm-Jan;
Wood, Andrew R.;
Yang, Jian;
Lui, Julian C.;
Vedantam, Sailaja;
Gustafsson, Stefan;
Esko, Tonu;
Frayling, Tim;
Speliotes, Elizabeth K.;
Boehnke, Michael;
Raychaudhuri, Soumya;
Fehrmann, Rudolf S. N.;
Hirschhorn, Joel N.;
Franke, Lude

Publication type:

Article

Clinical Features and Genetic Risk of Demyelination Following Anti-TNF Treatment.

Published in:

Journal of Crohn's & Colitis, 2020, v. 14, n. 12, p. 1653, doi. 10.1093/ecco-jcc/jjaa104

By:

Lin, Simeng;
Green, Harry D;
Hendy, Peter;
Heerasing, Neel M;
Chanchlani, Neil;
Hamilton, Benjamin;
Walker, Gareth J;
Heap, Graham A;
Hobart, Jeremy;
Martin, Roswell J;
Coles, Alasdair J;
Silverberg, Mark S;
Irving, Peter M;
Chung-Faye, Guy;
Silber, Eli;
Cummings, J R Fraser;
Lytvyak, Ellina;
Andersen, Vibeke;
Wood, Andrew R;
Tyrrell, Jessica

Publication type:

Article

Genome-Wide Association Study of Microscopic Colitis in the UK Biobank Confirms Immune-Related Pathogenesis.

Published in:

Journal of Crohn's & Colitis, 2019, v. 13, n. 12, p. 1578, doi. 10.1093/ecco-jcc/jjz104

By:

Green, Harry D;
Beaumont, Robin N;
Thomas, Amanda;
Hamilton, Benjamin;
Wood, Andrew R;
Sharp, Seth;
Jones, Samuel E;
Tyrrell, Jessica;
Walker, Gareth;
Goodhand, James;
Kennedy, Nicholas A;
Ahmad, Tariq;
Weedon, Michael N

Publication type:

Article

The impact of Mendelian sleep and circadian genetic variants in a population setting.

Published in:

PLoS Genetics, 2022, v. 18, n. 9, p. 1, doi. 10.1371/journal.pgen.1010356

By:

Weedon, Michael N.;
Jones, Samuel E.;
Lane, Jacqueline M.;
Lee, Jiwon;
Ollila, Hanna M.;
Dawes, Amy;
Tyrrell, Jess;
Beaumont, Robin N.;
Partonen, Timo;
Merikanto, Ilona;
Rich, Stephen S.;
Rotter, Jerome I.;
Frayling, Timothy M.;
Rutter, Martin K.;
Redline, Susan;
Sofer, Tamar;
Saxena, Richa;
Wood, Andrew R.

Publication type:

Article

Genetic Evidence for Causal Relationships Between Maternal Obesity-Related Traits and Birth Weight.

Published in:

2016

By:

Tyrrell, Jessica;
Richmond, Rebecca C.;
Palmer, Tom M.;
Feenstra, Bjarke;
Rangarajan, Janani;
Metrustry, Sarah;
Cavadino, Alana;
Paternoster, Lavinia;
Armstrong, Loren L.;
G. De Silva, N. Maneka;
Wood, Andrew R.;
Horikoshi, Momoko;
Geller, Frank;
Myhre, Ronny;
Bradfield, Jonathan P.;
Kreiner-Møller, Eskil;
Huikari, Ville;
Painter, Jodie N.;
Hottenga, Jouke-Jan;
Allard, Catherine

Publication type:

journal article

A Genome-Wide Association Study of IVGTT-Based Measures of First-Phase Insulin Secretion Refines the Underlying Physiology of Type 2 Diabetes Variants.

Published in:

2017

By:

Wood, Andrew R.;
Jonsson, Anna;
Jackson, Anne U.;
Nan Wang;
van Leewen, Nienke;
Palmer, Nicholette D.;
Sayuko Kobes;
Deelen, Joris;
Boquete-Vilarino, Lorena;
Paananen, Jussi;
Stanáčková, Alena;
Boomsma, Dorret I.;
de Geus, Eco J. C.;
Eekhoff, Elisabeth M. W.;
Fritsche, Andreas;
Kramer, Mark;
Nijpels, Giel;
Simonis-Bik, Annemarie;
van Haeften, Timon W.;
Mahajan, Anubha

Publication type:

journal article

Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart Disease.

Published in:

2016

By:

Yaghootkar, Hanieh;
Lotta, Luca A.;
Tyrrell, Jessica;
Smit, Roelof A. J.;
Jones, Sam E.;
Donnelly, Louise;
Beaumont, Robin;
Campbell, Archie;
Tuke, Marcus A.;
Hayward, Caroline;
Ruth, Katherine S.;
Padmanabhan, Sandosh;
Wouter Jukema, J.;
Palmer, Colin C.;
Hattersley, Andrew;
Freathy, Rachel M.;
Langenberg, Claudia;
Wareham, Nicholas J.;
Wood, Andrew R.;
Murray, Anna

Publication type:

journal article

Association Analysis of 29,956 Individuals Confirms That a Low-Frequency Variant at CCND2 Halves the Risk of Type 2 Diabetes by Enhancing Insulin Secretion.

Published in:

Diabetes, 2015, v. 64, n. 6, p. 2279, doi. 10.2337/db14-1456

By:

Yaghootkar, Hanieh;
Stancáková, Alena;
Freathy, Rachel M.;
Vangipurapu, Jagadish;
Weedon, Michael N.;
Weijia Xie;
Wood, Andrew R.;
Ferrannini, Ele;
Mari, Andrea;
Ring, Susan M.;
Lawlor, Debbie A.;
Smith, George Davey;
Jørgensen, Torben;
Hansen, Torben;
Pedersen, Oluf;
Steinthorsdottir, Valgerdur;
Guðbjartsson, Daniel F.;
Thorleifsson, Gudmar;
Thorsteinsdottir, Unnur;
Stefansson, Kari

Publication type:

Article

Targeted Allelic Expression Profiling in Human Islets Identifies cis-Regulatory Effects for Multiple Variants Identified by Type 2 Diabetes Genome-Wide Association Studies.

Published in:

Diabetes, 2015, v. 64, n. 4, p. 1484, doi. 10.2337/db14-0957

By:

Locke, Jonathan M.;
Hysenaj, Gerald;
Wood, Andrew R.;
Weedon, Michael N.;
Harries, Lorna W.

Publication type:

Article

Genetic Variants Associated With Glycine Metabolism and Their Role in Insulin Sensitivity and Type 2 Diabetes.

Published in:

Diabetes, 2013, v. 62, n. 6, p. 2141, doi. 10.2337/db12-0876

By:

Weijia Xie;
Wood, Andrew R.;
Lyssenko, Valeriya;
Weedon, Michael N.;
Knowles, Joshua W.;
Alkayyali, Sami;
Assimes, Themistocles L.;
Quertermous, Thomas;
Abbasi, Fahim;
Paananen, Jussi;
Häring, Hans;
Hansen, Torben;
Pedersen, Oluf;
Smith, Ulf;
Laakso, Markku;
Dekker, Jacqueline M.;
Nolan, John J.;
Groop, Leif;
Ferrannini, Ele;
Adam, Klaus-Peter

Publication type:

Article