Works by Wittenburg, Luke A.

Results: 30

Fractionated oral dosing and its effect on cyclophosphamide pharmacokinetics in dogs with high‐grade multicentric lymphoma.

Published in:

Veterinary & Comparative Oncology, 2023, v. 21, n. 1, p. 20, doi. 10.1111/vco.12856

By:

Veluvolu, Sridhar;
Willcox, Jennifer L.;
Skorupski, Katherine A.;
Al‐Nadaf, Sami;
Rebhun, Robert;
Wittenburg, Luke

Publication type:

Article

The interaction between RUNX2 and core binding factor beta as a potential therapeutic target in canine osteosarcoma.

Published in:

Veterinary & Comparative Oncology, 2020, v. 18, n. 1, p. 52, doi. 10.1111/vco.12526

By:

Alegre, Fernando;
Ormonde, Amanda R.;
Godinez, Dayn R.;
Illendula, Anuradha;
Bushweller, John H.;
Wittenburg, Luke A.

Publication type:

Article

Doxorubicin area under the curve is an important predictor of neutropenia in dogs with naturally occurring cancers.

Published in:

Veterinary & Comparative Oncology, 2019, v. 17, n. 2, p. 147, doi. 10.1111/vco.12455

By:

Wittenburg, Luke A.;
Weishaar, Kristen;
Ramirez, Dominique;
Gustafson, Daniel L.

Publication type:

Article

In vitro and in vivo activity of liposome‐encapsulated curcumin for naturally occurring canine cancers.

Published in:

Veterinary & Comparative Oncology, 2018, v. 16, n. 4, p. 571, doi. 10.1111/vco.12424

By:

Withers, Sita S.;
York, Daniel;
Johnson, Eric;
Al‐nadaf, Sami;
Skorupski, Katherine A.;
Rodriguez, Carlos O.;
Burton, Jenna H.;
Guerrero, Teri;
Sein, Kriste;
Wittenburg, Luke;
Rebhun, Robert B.

Publication type:

Article

Effect of topical naltrexone 0.3% on corneal sensitivity and tear parameters in normal brachycephalic dogs.

Published in:

Veterinary Ophthalmology, 2014, v. 17, n. 5, p. 328, doi. 10.1111/vop.12079

By:

Arnold, Trevor S.;
Wittenburg, Luke A.;
Powell, Cynthia C.

Publication type:

Article

A genetically engineered microRNA-34a prodrug demonstrates anti-tumor activity in a canine model of osteosarcoma.

Published in:

PLoS ONE, 2018, v. 13, n. 12, p. 1, doi. 10.1371/journal.pone.0209941

By:

Alegre, Fernando;
Ormonde, Amanda R.;
Snider, Kellie M.;
Woolard, Kevin;
Yu, Ai-Ming;
Wittenburg, Luke A.

Publication type:

Article

The Effects of Mepivacaine Hydrochloride on Antimicrobial Activity and Mechanical Nociceptive Threshold During Amikacin Sulfate Regional Limb Perfusion in the Horse.

Published in:

Veterinary Surgery, 2016, v. 45, n. 6, p. 798, doi. 10.1111/vsu.12515

By:

Colbath, Aimée C.;
Wittenburg, Luke A.;
Gold, Jenifer R.;
McIlwraith, C. Wayne;
Moorman, Valerie J.

Publication type:

Article

A systems biology approach to identify molecular pathways altered by HDAC inhibition in osteosarcoma.

Published in:

Journal of Cellular Biochemistry, 2012, v. 113, n. 3, p. 773, doi. 10.1002/jcb.23403

By:

Wittenburg, Luke A.;
Ptitsyn, Andrey A.;
Thamm, Douglas H.

Publication type:

Article

Decoupling the Transcriptional and Translational Roles of Core Binding Factor Beta to Identify Novel Therapeutic Targets in Osteosarcoma.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3294

By:

Oldberg, Nicholas A.;
Godinez, Dayn R.;
Wittenburg, Luke A.

Publication type:

Article

Inhibition of Core Binding Factor Transcriptional Complex Provides a Novel Pharmacological Target for Osteosarcoma.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.0R279

By:

Godinez, Dayn R.;
Oldberg, Nicholas;
Wittenburg, Luke A.

Publication type:

Article

The Novel Protein, Olfactomedin‐like 3, Alters Microglia Biology and May Contribute to Glioma Progression.

Published in:

FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.04385

By:

Toedebusch, Ryan;
Wittenburg, Luke;
Debebe, Eshetu;
Lucchesi, Chris;
Toedebusch, Christine

Publication type:

Article

The histone deacetylase inhibitor valproic acid sensitizes human and canine osteosarcoma to doxorubicin.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 1, p. 83, doi. 10.1007/s00280-010-1287-z

By:

Wittenburg, Luke;
Bisson, Liam;
Rose, Barbara;
Korch, Christopher;
Thamm, Douglas

Publication type:

Article

Pilot study comparing serum chemotherapy levels after intra-arterial and intravenous administration in dogs with naturally occurring urinary tract tumors.

Published in:

Canadian Journal of Veterinary Research / Revue Canadienne de Recherche Vétérinaire, 2019, v. 83, n. 3, p. 187

By:

Kirsch, Meghan;
Weisse, Chick;
Berent, Allyson;
Clifford, Craig;
Leibman, Nicole;
Wittenburg, Luke;
Solomon, Stephen B.;
Lamb, Kenneth

Publication type:

Article

Pharmacokinetics of cannabidiol administered by 3 delivery methods at 2 different dosages to healthy dogs.

Published in:

Canadian Journal of Veterinary Research / Revue Canadienne de Recherche Vétérinaire, 2018, v. 82, n. 3, p. 178

By:

Bartner, Lisa R.;
McGrath, Stephanie;
Rao, Sangeeta;
Hyatt, Linda K.;
Wittenburg, Luke A.

Publication type:

Article

Effect of standard‐dose and high‐dose pimobendan on select indices of renal and cardiac function in dogs with American College of Veterinary Internal Medicine stage B2 myxomatous mitral valve disease.

Published in:

Journal of Veterinary Internal Medicine, 2022, v. 36, n. 6, p. 1892, doi. 10.1111/jvim.16537

By:

Kaplan, Joanna L.;
Visser, Lance C.;
Gunther‐Harrington, Catherine T.;
Ontiveros, Eric S.;
Wittenburg, Luke A.;
Palm, Carrie A.;
Stern, Joshua A.

Publication type:

Article

Pharmacokinetic study comparing doxorubicin concentrations after chemoembolization or intravenous administration in dogs with naturally occurring nonresectable hepatic carcinoma.

Published in:

Journal of Veterinary Internal Medicine, 2022, v. 36, n. 5, p. 1792, doi. 10.1111/jvim.16520

By:

Samuel, Nina;
Weisse, Chick;
Berent, Allyson C.;
Rogatko, Cléo P.;
Wittenburg, Luke;
Lamb, Kenneth

Publication type:

Article

Pharmacokinetics of isavuconazole in healthy cats after oral and intravenous administration.

Published in:

Journal of Veterinary Internal Medicine, 2022, v. 36, n. 4, p. 1422, doi. 10.1111/jvim.16452

By:

Woerde, Dennis J.;
Wittenburg, Luke A.;
Dear, Jonathan D.

Publication type:

Article

In vivo and in vitro assessment of mirtazapine pharmacokinetics in cats with liver disease.

Published in:

Journal of Veterinary Internal Medicine, 2018, v. 32, n. 6, p. 1951, doi. 10.1111/jvim.15237

By:

Fitzpatrick, Rikki L.;
Quimby, Jessica M.;
Benson, Kellyi K.;
Ramirez, Dominique;
Sieberg, Liberty G.;
Wittenburg, Luke A.;
Gustafson, Daniel L.

Publication type:

Article

Vinblastine pharmacokinetics in mouse, dog, and human in the context of a physiologically based model incorporating tissue-specific drug binding, transport, and metabolism.

Published in:

Pharmacology Research & Perspectives, 2023, v. 11, n. 1, p. 1, doi. 10.1002/prp2.1052

By:

Witta, Sandra;
Collins, Keagan P.;
Ramirez, Dominique A.;
Mannheimer, Joshua D.;
Wittenburg, Luke A.;
Gustafson, Daniel L.

Publication type:

Article

Cardiac myosin inhibitor, CK-586, minimally reduces systolic function and ameliorates obstruction in feline hypertrophic cardiomyopathy.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-62840-3

By:

Rivas, Victor N.;
Crofton, Amanda E.;
Jauregui, Carina E.;
Wouters, Jalena R.;
Yang, Betty S.;
Wittenburg, Luke A.;
Kaplan, Joanna L.;
Hwee, Darren T.;
Murphy, Anne N.;
Morgan, Bradley P.;
Malik, Fady I.;
Harris, Samantha P.;
Stern, Joshua A.

Publication type:

Article

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma.

Published in:

Autophagy, 2014, v. 10, n. 8, p. 1415, doi. 10.4161/auto.29165

By:

Barnard, Rebecca A.;
Wittenburg, Luke A.;
Amaravadi, Ravi K.;
Gustafson, Daniel L.;
Thorburn, Andrew;
Thamm, Douglas H.

Publication type:

Article

Correction: Cook et al. An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats. Viruses 2022, 14 , 2429

Published in:

2024

By:

Cook, Sarah;
Wittenburg, Luke;
Yan, Victoria C.;
Theil, Jacob H.;
Castillo, Diego;
Reagan, Krystle L.;
Williams, Sonyia;
Pham, Cong-Dat;
Li, Chun;
Muller, Florian L.;
Murphy, Brian G.

Publication type:

Correction Notice

An Optimized Bioassay for Screening Combined Anticoronaviral Compounds for Efficacy against Feline Infectious Peritonitis Virus with Pharmacokinetic Analyses of GS-441524, Remdesivir, and Molnupiravir in Cats.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 11, p. 2429, doi. 10.3390/v14112429

By:

Cook, Sarah;
Wittenburg, Luke;
Yan, Victoria C.;
Theil, Jacob H.;
Castillo, Diego;
Reagan, Krystle L.;
Williams, Sonyia;
Pham, Cong-Dat;
Li, Chun;
Muller, Florian L.;
Murphy, Brian G.

Publication type:

Article

Serum concentrations of gabapentin in cats with chronic kidney disease.

Published in:

Journal of Feline Medicine & Surgery, 2022, v. 24, n. 12, p. 1260, doi. 10.1177/1098612X221077017

By:

Quimby, Jessica M;
Lorbach, Sarah K;
Saffire, Ashlie;
Kennedy, Amanda;
Wittenburg, Luke A;
Aarnes, Turi K;
Creighton, Karina J;
Jones, Sarah E;
Paschall, Rene E;
King, Emily M;
Bruner, Clara E;
Wallinger, Jessica N;
van Haaften, Karen A

Publication type:

Article

Preliminary pharmacokinetics of intravenous and subcutaneous dolasetron and pharmacodynamics of subcutaneous dolasetron in healthy cats.

Published in:

Journal of Feline Medicine & Surgery, 2018, v. 20, n. 8, p. 721, doi. 10.1177/1098612X17729310

By:

Herndon, Andrea K.;
Quimby, Jessica M.;
Sieberg, Liberty G.;
Davis, Leigh;
Caress, Amber L.;
Ligas, Sabina;
Hansen, Ryan J.;
Wittenburg, Luke A.;
Gustafson, Danial L.

Publication type:

Article

Assessment of absorption of transdermal ondansetron in normal research cats.

Published in:

Journal of Feline Medicine & Surgery, 2017, v. 19, n. 12, p. 1245, doi. 10.1177/1098612X16688807

By:

Zajic, Lara B.;
Herndon, Andrea K.;
Sieberg, Liberty G.;
Caress, Amber L.;
Morgan, Paula K.;
Hansen, Ryan J.;
Wittenburg, Luke A.;
Gustafson, Daniel L.;
Quimby, Jessica M.

Publication type:

Article

Drug exposure and clinical effect of transdermal mirtazapine in healthy young cats: a pilot study.

Published in:

Journal of Feline Medicine & Surgery, 2017, v. 19, n. 10, p. 998, doi. 10.1177/1098612X16667168

By:

Benson, Kellyi K.;
Zajic, Lara B.;
Morgan, Paula K.;
Brown, Sarah R.;
Hansen, Ryan J.;
Lunghofer, Paul J.;
Wittenburg, Luke A.;
Gustafson, Daniel L.;
Quimby, Jessica M.

Publication type:

Article

Microglia-Derived Olfactomedin-like 3 Is a Potent Angiogenic Factor in Primary Mouse Brain Endothelial Cells: A Novel Target for Glioblastoma.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 23, p. 14613, doi. 10.3390/ijms232314613

By:

Joseph, Laila M.;
Toedebusch, Ryan G.;
Debebe, Eshetu;
Bastian, Aurelie H.;
Lucchesi, Christopher A.;
Syed-Quadri, Shafee;
Wittenburg, Luke A.;
Chen, Xinbin;
Meyers, Frederick J.;
Toedebusch, Christine M.

Publication type:

Article

Microglia-Derived Olfactomedin-like 3 Promotes Pro-Tumorigenic Microglial Function and Malignant Features of Glioma Cells.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 13052, doi. 10.3390/ijms222313052

By:

Toedebusch, Ryan G.;
Lucchesi, Christopher A.;
Debebe, Eshetu T.;
Wittenburg, Luke A.;
Chen, Xinbin;
Toedebusch, Christine M.

Publication type:

Article

Prevalence and Clinicopathologic Features of Canine Metastatic Melanoma Involving the Central Nervous System: A Retrospective Analysis and Comparative Review.

Published in:

Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.868004

By:

Razmara, Aryana M.;
Wittenburg, Luke A.;
Al-Nadaf, Sami;
Toedebusch, Ryan G.;
Meyers, Frederick J.;
Toedebusch, Christine M.

Publication type:

Article