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Rapid In Vivo Validation of HDAC Inhibitor-Based Treatments in Neuroblastoma Zebrafish Xenografts.
- Published in:
- Pharmaceuticals (14248247), 2020, v. 13, n. 11, p. 345, doi. 10.3390/ph13110345
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- Publication type:
- Article
Beyond germline genetic testing - heterozygous pathogenic variants in PMS2 in two children with Osteosarcoma and Ependymoma.
- Published in:
- 2023
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- Publication type:
- Case Study
Long-term follow-up of surgical intervention pattern in pediatric low-grade gliomas: report from the German SIOP-LGG 2004 cohort.
- Published in:
- Journal of Neurosurgery: Pediatrics, 2022, v. 30, n. 3, p. 318, doi. 10.3171/2022.6.PEDS22108
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- Publication type:
- Article
The early evolutionary landscape of osteosarcoma provides clues for targeted treatment strategies.
- Published in:
- Journal of Pathology, 2021, v. 254, n. 5, p. 556, doi. 10.1002/path.5699
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- Publication type:
- Article
An activated mutant BRAF kinase domain is sufficient to induce pilocytic astrocytoma in mice.
- Published in:
- 2011
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- Publication type:
- journal article
MYCN and HDAC2 cooperate to repress miR-183 signaling in neuroblastoma.
- Published in:
- Nucleic Acids Research, 2013, v. 41, n. 12, p. 6018, doi. 10.1093/nar/gkt346
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- Publication type:
- Article
Design and Synthesis of Dihydroxamic Acids as HDAC6/8/10 Inhibitors.
- Published in:
- ChemMedChem, 2020, v. 15, n. 13, p. 1163, doi. 10.1002/cmdc.202000149
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- Publication type:
- Article
Research with Vulnerable People: A Targeted Interdisciplinary Discussion within the Scope of the WMA Declaration of Helsinki Revision.
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- World Medical Journal, 2024, v. 70, n. 1, p. 54
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- Publication type:
- Article
Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma.
- Published in:
- Acta Neuropathologica Communications, 2015, v. 3, n. 1, p. 121, doi. 10.1186/s40478-015-0201-7
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- Publication type:
- Article
Treatment of pediatric patients and young adults with particle therapy at the Heidelberg Ion Therapy Center (HIT): establishment of workflow and initial clinical data.
- Published in:
- Radiation Oncology, 2012, v. 7, n. 1, p. 170, doi. 10.1186/1748-717X-7-170
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- Publication type:
- Article
Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age - a multicenter retrospective study.
- Published in:
- 2019
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- Publication type:
- journal article
EFFECTS: an expanded access program of everolimus for patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex.
- Published in:
- 2016
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- Publication type:
- journal article
Monitoring futility and efficacy in phase II trials with Bayesian posterior distributions—A calibration approach.
- Published in:
- Biometrical Journal, 2019, v. 61, n. 3, p. 488, doi. 10.1002/bimj.201700209
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- Publication type:
- Article
No correlation between NF1 mutation position and risk of optic pathway glioma in 77 unrelated NF1 patients.
- Published in:
- Human Genetics, 2016, v. 135, n. 5, p. 469, doi. 10.1007/s00439-016-1646-x
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- Publication type:
- Article
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.
- Published in:
- Cancers, 2021, v. 13, n. 17, p. 4476, doi. 10.3390/cancers13174476
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- Publication type:
- Article
Neurocognitive Outcomes in Pediatric Patients Following Brain Irradiation.
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- Cancers, 2021, v. 13, n. 14, p. 3538, doi. 10.3390/cancers13143538
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- Publication type:
- Article
ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein.
- Published in:
- Molecular Oncology, 2023, v. 17, n. 1, p. 37, doi. 10.1002/1878-0261.13318
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- Publication type:
- Article
DNA methylation-based classifier and gene expression signatures detect BRCAness in osteosarcoma.
- Published in:
- PLoS Computational Biology, 2021, v. 17, n. 11, p. 1, doi. 10.1371/journal.pcbi.1009562
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- Publication type:
- Article
A multi-institutional series of a novel, recurrent TRIM24::MET fusion-driven infant-type hemispheric glioma reveals significant clinico-pathological heterogeneity.
- Published in:
- Acta Neuropathologica Communications, 2024, v. 12, n. 1, p. 1, doi. 10.1186/s40478-024-01817-9
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- Publication type:
- Article
Adaption of neurosurgical resection patterns for pediatric low‐grade glioma spanning two decades—Report from the German LGG‐studies 1996–2018.
- Published in:
- Cancer Medicine, 2024, v. 13, n. 12, p. 1, doi. 10.1002/cam4.7417
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- Publication type:
- Article
Local and systemic therapy of recurrent ependymoma in children and adolescents: short- and long-term results of the E-HIT-REZ 2005 study.
- Published in:
- Neuro-Oncology, 2021, v. 23, n. 6, p. 1012, doi. 10.1093/neuonc/noaa276
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- Publication type:
- Article
MEDU-01. HDACi AND PLK1i ACT SYNERGISTICALLY IN MYC-AMPLIFIED MEDULLOBLASTOMA.
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii103, doi. 10.1093/neuonc/noz036.161
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- Publication type:
- Article
LGG-11. ESTABLISHMENT OF A HUMAN 3-DIMENSIONAL LOW-GRADE GLIOMA TUMOR MODEL IN INDUCED PLURIPOTENT STEM CELL DERIVED BRAIN ORGANOIDS.
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii101, doi. 10.1093/neuonc/noz036.154
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- Publication type:
- Article
GENE-12. ANAPLASTIC NEUROEPITHELIAL TUMOR WITH CONDENSED NUCLEI (ANTCON): A NOVEL BRAIN TUMOR ENTITY WITH RECURRENT NTRK FUSION.
- Published in:
- Neuro-Oncology, 2019, v. 21, p. ii83, doi. 10.1093/neuonc/noz036.083
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- Publication type:
- Article
Preclinical drug screen reveals topotecan, actinomycin D, and volasertib as potential new therapeutic candidates for ETMR brain tumor patients.
- Published in:
- Neuro-Oncology, 2017, v. 19, n. 12, p. 1607, doi. 10.1093/neuonc/nox093
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- Publication type:
- Article
INFORMING TREATMENT DECISIONS IN RELAPSED PEDIATRIC MALIGNANCIES USING NEXT-GENERATION DIAGNOSTICS.
- Published in:
- Neuro-Oncology, 2014, v. 16, n. suppl_3, p. iii24
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- Publication type:
- Article
Neurosurgical morbidity in pediatric supratentorial midline low‐grade glioma: Results from the German LGG studies.
- Published in:
- International Journal of Cancer, 2023, v. 153, n. 8, p. 1487, doi. 10.1002/ijc.34615
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- Publication type:
- Article
Histone deacetylase inhibitor Helminthosporium carbonum (HC)-toxin suppresses the malignant phenotype of neuroblastoma cells.
- Published in:
- International Journal of Cancer, 2008, v. 122, n. 8, p. 1891, doi. 10.1002/ijc.23295
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- Publication type:
- Article
Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors.
- Published in:
- Brain Pathology, 2016, v. 26, n. 4, p. 506, doi. 10.1111/bpa.12326
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- Publication type:
- Article
Nestin Expression Identifies Ependymoma Patients with Poor Outcome.
- Published in:
- Brain Pathology, 2012, v. 22, n. 6, p. 848, doi. 10.1111/j.1750-3639.2012.00600.x
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- Publication type:
- Article
Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.
- Published in:
- Clinical Pharmacology & Therapeutics, 2023, v. 114, n. 4, p. 904, doi. 10.1002/cpt.3002
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- Publication type:
- Article
A Study of Regulatory Challenges of Pediatric Oncology Phase I/II Trial Submissions and Guidance on Protocol Development.
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- Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 4, p. 1025, doi. 10.1002/cpt.2319
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- Publication type:
- Article
Adaptive designs with arbitrary dependence structure.
- Published in:
- Biometrical Journal, 2014, v. 56, n. 1, p. 86, doi. 10.1002/bimj.201200234
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- Publication type:
- Article
Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma.
- Published in:
- Neuro-Oncology Advances, 2022, v. 4, n. 1, p. 1, doi. 10.1093/noajnl/vdac026
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- Publication type:
- Article
Loss of efficacy of subsequent nonsurgical therapy after primary treatment failure in pediatric low‐grade glioma patients—Report from the German SIOP‐LGG 2004 cohort.
- Published in:
- International Journal of Cancer, 2020, v. 147, n. 12, p. 3471, doi. 10.1002/ijc.33170
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- Publication type:
- Article
Favorable prognosis in pediatric brainstem low‐grade glioma: Report from the German SIOP‐LGG 2004 cohort.
- Published in:
- International Journal of Cancer, 2020, v. 146, n. 12, p. 3385, doi. 10.1002/ijc.32734
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- Publication type:
- Article
Oncolytic effects of parvovirus H-1 in medulloblastoma are associated with repression of master regulators of early neurogenesis.
- Published in:
- International Journal of Cancer, 2014, v. 134, n. 3, p. 703, doi. 10.1002/ijc.28386
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- Publication type:
- Article
HDAC11 is a novel drug target in carcinomas.
- Published in:
- International Journal of Cancer, 2013, v. 132, n. 9, p. 2200, doi. 10.1002/ijc.27876
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- Publication type:
- Article
Parvovirus H1 selectively induces cytotoxic effects on human neuroblastoma cells.
- Published in:
- International Journal of Cancer, 2010, v. 127, n. 5, p. 1230, doi. 10.1002/ijc.25168
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- Publication type:
- Article
Long-Term Use of Everolimus in Patients with Tuberous Sclerosis Complex: Final Results from the EXIST-1 Study.
- Published in:
- PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0158476
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- Publication type:
- Article
MAPK pathway activation in pilocytic astrocytoma.
- Published in:
- Cellular & Molecular Life Sciences, 2012, v. 69, n. 11, p. 1799, doi. 10.1007/s00018-011-0898-9
- By:
- Publication type:
- Article
Synergy of retinoic acid and BH3 mimetics in MYC(N)-driven embryonal nervous system tumours.
- Published in:
- British Journal of Cancer, 2024, v. 131, n. 4, p. 763, doi. 10.1038/s41416-024-02740-5
- By:
- Publication type:
- Article
Clinical evidence for a biological effect of epigenetically active decitabine in relapsed or progressive rhabdoid tumors.
- Published in:
- 2021
- By:
- Publication type:
- journal article
Response in a child with a BRAF V600E mutated desmoplastic infantile astrocytoma upon retreatment with vemurafenib.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Hematologic Response to Vorinostat Treatment in Relapsed Myeloid Leukemia of Down Syndrome.
- Published in:
- 2016
- By:
- Publication type:
- journal article
Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome.
- Published in:
- Genes, Chromosomes & Cancer, 2009, v. 48, n. 7, p. 558, doi. 10.1002/gcc.20665
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- Publication type:
- Article
Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma.
- Published in:
- Genes, Chromosomes & Cancer, 2009, v. 48, n. 3, p. 229, doi. 10.1002/gcc.20635
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- Publication type:
- Article
The HDAC6/8/10 inhibitor TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.
- Published in:
- Archives of Toxicology, 2018, v. 92, n. 8, p. 2649, doi. 10.1007/s00204-018-2234-8
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- Publication type:
- Article
Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics.
- Published in:
- Acta Neuropathologica, 2023, v. 146, n. 6, p. 853, doi. 10.1007/s00401-023-02638-1
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- Publication type:
- Article
Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts.
- Published in:
- Acta Neuropathologica, 2023, v. 145, n. 1, p. 97, doi. 10.1007/s00401-022-02522-4
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- Publication type:
- Article