Works by Wira, Charles

Results: 104

Composition of the Sepsis Definitions Task Force.

Published in:

2016

By:

Wira III, Charles R.;
Swenson, Kai E.;
Wira, Charles R 3rd

Publication type:

commentary

Evaluation of a novel 5-group classification system of sepsis by vasopressor use and initial serum lactate in the emergency department.

Published in:

2018

By:

Swenson, Kai E.;
Dziura, James D.;
Aydin, Ani;
Reynolds, Jesse;
Wira, Charles R.;
Wira, Charles R 3rd

Publication type:

journal article

Diagnostic yield of an abbreviated MRI protocol in the evaluation of dizziness in the emergency department, a single institutional experience.

Published in:

Emergency Radiology, 2025, v. 32, n. 4, p. 559, doi. 10.1007/s10140-025-02349-y

By:

Shareef, Faryal;
Tu, Long;
Neupane, Anish;
Siddique, Zaid;
Joshi, Rudra;
Melnick, Edward;
Wira, Charles;
Mahajan, Amit

Publication type:

Article

Increases in the susceptibility of human endometrial CD4+ T cells to HIV-1 infection post-menopause are not dependent on greater viral receptor expression frequency.

Published in:

Frontiers in Immunology, 2025, p. 1, doi. 10.3389/fimmu.2024.1506653

By:

vom Steeg, Landon G.;
Shen, Zheng;
Collins, Jane;
Patel, Mickey V.;
Barr, Fiona D.;
Hopkins, Daniel C.;
Ochsenbauer, Christina;
Wira, Charles R.

Publication type:

Article

Human genital dendritic cell heterogeneity confers differential rapid response to HIV-1 exposure.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1472656

By:

Parthasarathy, Siddharth;
Moreno de Lara, Laura;
Carrillo-Salinas, Francisco J.;
Werner, Alexandra;
Borchers, Anna;
Iyer, Vidya;
Vogell, Alison;
Fortier, Jared M.;
Wira, Charles R.;
Rodriguez-Garcia, Marta

Publication type:

Article

Impact of aging on the frequency, phenotype, and function of CD4+ T cells in the human female reproductive tract.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2024.1465124

By:

Zheng Shen;
Steeg, Landon G. vom;
Patel, Mickey V.;
Rodriguez-Garcia, Marta;
Wira, Charles R.

Publication type:

Article

Methodology for Low-Field, Portable Magnetic Resonance Neuroimaging at the Bedside.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.760321

By:

Prabhat, Anjali M.;
Crawford, Anna L.;
Mazurek, Mercy H.;
Yuen, Matthew M.;
Chavva, Isha R.;
Ward, Adrienne;
Hofmann Jr., William V.;
Timario, Nona;
Qualls, Stephanie R.;
Helland, Juliana;
Wira, Charles;
Sze, Gordon;
Rosen, Matthew S.;
Kimberly, William Taylor;
Sheth, Kevin N.

Publication type:

Article

Mouse estrous cycle regulation of vaginal versus uterine cytokines, chemokines, α-/β-defensins and TLRs.

Published in:

Innate Immunity, 2013, v. 19, n. 2, p. 121, doi. 10.1177/1753425912454026

By:

Hickey, Danica K;
Fahey, John V;
Wira, Charles R

Publication type:

Article

Prognostication of post-cardiac arrest coma: early clinical and electroencephalographic predictors of outcome.

Published in:

Intensive Care Medicine, 2015, v. 41, n. 7, p. 1264, doi. 10.1007/s00134-015-3834-x

By:

Sivaraju, Adithya;
Gilmore, Emily;
Wira, Charles;
Stevens, Anna;
Rampal, Nishi;
Moeller, Jeremy;
Greer, David;
Hirsch, Lawrence;
Gaspard, Nicolas

Publication type:

Article

Considering Adverse Effects of Common Antihypertensive Medications in the ED.

Published in:

Current Hypertension Reports, 2024, v. 26, n. 8, p. 355, doi. 10.1007/s11906-024-01304-5

By:

Wira III, Charles R.;
Kearns, Thomas;
Fleming-Nouri, Alex;
Tyrrell, John D.;
Wira, Christina M.;
Aydin, Ani

Publication type:

Article

A review of micronutrients in sepsis: the role of thiamine, l-carnitine, vitamin C, selenium and vitamin D.

Published in:

Nutrition Research Reviews, 2018, v. 31, n. 2, p. 281, doi. 10.1017/S0954422418000124

By:

Belsky, Justin B.;
Wira, Charles R.;
Jacob, Vinitha;
Sather, John E.;
Lee, Patty J.

Publication type:

Article

Innate and adaptive immunity in female genital tract: cellular responses and interactions.

Published in:

Immunological Reviews, 2005, v. 206, n. 1, p. 306, doi. 10.1111/j.0105-2896.2005.00287.x

By:

Wira, Charles R.;
Fahey, John V.;
Sentman, Charles L.;
Pioli, Patricia A.;
Shen, Li

Publication type:

Article

Tenofovir Inhibits Wound Healing of Epithelial Cells and Fibroblasts from the Upper and Lower Human Female Reproductive Tract.

Published in:

Scientific Reports, 2017, p. 45725, doi. 10.1038/srep45725

By:

Rodriguez-Garcia, Marta;
Patel, Mickey V.;
Shen, Zheng;
Bodwell, Jack;
Rossoll, Richard M.;
Wira, Charles R.

Publication type:

Article

Sex Hormones and Aging Modulate Interferon Lambda 1 Production and Signaling by Human Uterine Epithelial Cells and Fibroblasts.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.718380

By:

Patel, Mickey V.;
Hopkins, Daniel C.;
Barr, Fiona D.;
Wira, Charles R.

Publication type:

Article

Endometrial Cancer Suppresses CD8+ T Cell-Mediated Cytotoxicity in Postmenopausal Women.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.657326

By:

Patel, Mickey V.;
Shen, Zheng;
Rodriguez-Garcia, Marta;
Usherwood, Edward J.;
Tafe, Laura J.;
Wira, Charles R.

Publication type:

Article

Sex as a Biological Variable in Emergency Medicine Research and Clinical Practice: A Brief Narrative Review.

Published in:

Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health, 2017, v. 18, n. 6, p. 1079, doi. 10.5811/westjem.2017.8.34997

By:

McGregor, Alyson J.;
Beauchamp, Gillian A.;
Wira III, Charles R.;
Perman, Sarah M.;
Safdar, Basmah

Publication type:

Article

Lactate Clearance Predicts Survival Among Patients in the Emergency Department with Severe Sepsis.

Published in:

Western Journal of Emergency Medicine: Integrating Emergency Care with Population Health, 2015, v. 16, n. 7, p. 1118, doi. 10.5811/westjem.2015.10.27577

By:

Bhat, Sundeep R.;
Swenson, Kai E.;
Wira, Charles R.;
Francis, Melissa W.

Publication type:

Article

Guiding Cardiopulmonary Resuscitation with Focused Echocardiography: A Report of Five Cases.

Published in:

Prehospital Emergency Care, 2020, v. 24, n. 2, p. 297, doi. 10.1080/10903127.2019.1626955

By:

Liu, Rachel B.;
Bogucki, Sandy;
Marcolini, Evie G.;
Yu, Connie Y.;
Wira, Charles R.;
Kalam, Sharmin;
Daley, James;
Moore, Chris L.;
Cone, David C.

Publication type:

Article

Medroxyprogesterone acetate inhibits wound closure of human endometrial epithelial cells and stromal fibroblasts in vitro.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02681-6

By:

Patel, Mickey V.;
Rodriguez-Garcia, Marta;
Shen, Zheng;
Wira, Charles R.

Publication type:

Article

Cause of an Elevated Lactate Level.

Published in:

2015

By:

Swenson, Kai E.;
Wira, Charles R.

Publication type:

Letter to the Editor

Aging Selectively Alters PRR and ISG Expression in Endo‐ and Ecto‐Cervical Stromal Fibroblasts From the Human Female Reproductive Tract.

Published in:

American Journal of Reproductive Immunology, 2025, v. 93, n. 1, p. 1, doi. 10.1111/aji.70031

By:

Patel, Mickey V.;
Shen, Zheng;
Hopkins, Daniel C.;
Barr, Fiona D.;
Wira, Charles R.

Publication type:

Article

Estradiol‐regulated innate antiviral responses of human endometrial stromal fibroblasts.

Published in:

American Journal of Reproductive Immunology, 2018, v. 80, n. 5, p. N.PAG, doi. 10.1111/aji.13042

By:

Patel, Mickey V.;
Shen, Zheng;
Rossoll, Richard M.;
Wira, Charles R.

Publication type:

Article

Chlamydia trachomatis regulates innate immune barrier integrity and mediates cytokine and antimicrobial responses in human uterine ECC-1 epithelial cells.

Published in:

American Journal of Reproductive Immunology, 2017, v. 78, n. 6, p. n/a, doi. 10.1111/aji.12764

By:

Mukura, Lucy Rudo;
Hickey, Danica K.;
Rodriguez‐Garcia, Marta;
Fahey, John V.;
Wira, Charles R.

Publication type:

Article

Characterization of immune cells and infection by HIV in human ovarian tissues.

Published in:

American Journal of Reproductive Immunology, 2017, v. 78, n. 1, p. n/a, doi. 10.1111/aji.12687

By:

Shen, Zheng;
Rodriguez‐Garcia, Marta;
Ochsenbauer, Christina;
Wira, Charles R.

Publication type:

Article

Menopausal status influences the expression of programmed death ( PD)-1 and its ligand PD-L1 on immune cells from the human female reproductive tract.

Published in:

American Journal of Reproductive Immunology, 2016, v. 76, n. 2, p. 118, doi. 10.1111/aji.12532

By:

Shen, Zheng;
Rodriguez‐Garcia, Marta;
Patel, Mickey V.;
Barr, Fiona D.;
Wira, Charles R.

Publication type:

Article

The Role of Sex Hormones and the Tissue Environment in Immune Protection Against HIV in the Female Reproductive Tract.

Published in:

American Journal of Reproductive Immunology, 2014, v. 72, n. 2, p. 171, doi. 10.1111/aji.12235

By:

Wira, Charles R.;
Rodriguez-Garcia, Marta;
Shen, Zheng;
Patel, Mickey;
Fahey, John V.

Publication type:

Article

Regulation of Mucosal Immunity in the Female Reproductive Tract: The Role of Sex Hormones in Immune Protection Against Sexually Transmitted Pathogens.

Published in:

American Journal of Reproductive Immunology, 2014, v. 72, n. 2, p. 236, doi. 10.1111/aji.12252

By:

Wira, Charles R.;
Fahey, John V.;
Rodriguez-Garcia, Marta;
Shen, Zheng;
Patel, Mickey V.

Publication type:

Article

Estradiol Regulation of Constitutive and Keratinocyte Growth Factor-Induced CCL20 and CXCL1 Secretion by Mouse Uterine Epithelial Cells.

Published in:

American Journal of Reproductive Immunology, 2014, v. 72, n. 1, p. 34, doi. 10.1111/aji.12260

By:

Haddad, Severina N.;
Wira, Charles R.

Publication type:

Article

Innate Immunity in the Vagina (Part II): Anti- HIV Activity and Antiviral Content of Human Vaginal Secretions.

Published in:

American Journal of Reproductive Immunology, 2014, v. 72, n. 1, p. 22, doi. 10.1111/aji.12218

By:

Patel, Mickey V.;
Ghosh, Mimi;
Fahey, John V.;
Ochsenbauer, Christina;
Rossoll, Richard M.;
Wira, Charles R.

Publication type:

Article

Innate Immunity in the Vagina (Part I): Estradiol Inhibits HBD2 and Elafin Secretion by Human Vaginal Epithelial Cells.

Published in:

American Journal of Reproductive Immunology, 2013, v. 69, n. 5, p. 463, doi. 10.1111/aji.12078

By:

Patel, Mickey V.;
Fahey, John V.;
Rossoll, Richard M.;
Wira, Charles R.

Publication type:

Article

Immunobiology of Genital Tract Trauma: Endocrine Regulation of HIV Acquisition in Women Following Sexual Assault or Genital Tract Mutilation.

Published in:

American Journal of Reproductive Immunology, 2013, v. 69, p. 51, doi. 10.1111/aji.12027

By:

Ghosh, Mimi;
Rodriguez-Garcia, Marta;
Wira, Charles R.

Publication type:

Article

Sexual Violence and Genital Injury: The Physiology of HIV Transmission Risk.

Published in:

American Journal of Reproductive Immunology, 2013, v. 69, p. 2, doi. 10.1111/aji.12037

By:

Klot, Jennifer F.;
Wira, Charles R.

Publication type:

Article

Estrogen Receptor α Antagonists Mediate Changes in CCL20 and CXCL1 Secretions in the Murine Female Reproductive Tract.

Published in:

American Journal of Reproductive Immunology, 2013, v. 69, n. 2, p. 159, doi. 10.1111/aji.12021

By:

Hickey, Danica K.;
Fahey, John V.;
Wira, Charles R.

Publication type:

Article

Pathogen Recognition in the Human Female Reproductive Tract: Expression of Intracellular Cytosolic Sensors NOD1, NOD2, RIG-1, and MDA5 and response to HIV-1 and Neisseria gonorrhea.

Published in:

American Journal of Reproductive Immunology, 2013, v. 69, n. 1, p. 41, doi. 10.1111/aji.12019

By:

Ghosh, Mimi;
Shen, Zheng;
Fahey, John V.;
Crist, Sarah G.;
Patel, Mickey;
Smith, Jennifer M.;
Wira, Charles R.

Publication type:

Article

A Subset of Human Uterine Endometrial Macrophages is Alternatively Activated.

Published in:

American Journal of Reproductive Immunology, 2012, v. 68, n. 5, p. 374, doi. 10.1111/j.1600-0897.2012.01181.x

By:

Jensen, Amy L.;
Collins, Jane;
Shipman, Emilie P.;
Wira, Charles R.;
Guyre, Paul M.;
Pioli, Patricia A.

Publication type:

Article

The impact of aging on innate and adaptive immunity in the human female genital tract.

Published in:

Aging Cell, 2021, v. 20, n. 5, p. 1, doi. 10.1111/acel.13361

By:

Rodriguez‐Garcia, Marta;
Patel, Mickey V.;
Shen, Zheng;
Wira, Charles R.

Publication type:

Article

Aging impacts CD103+CD8+ T cell presence and induction by dendritic cells in the genital tract.

Published in:

Aging Cell, 2018, v. 17, n. 3, p. 1, doi. 10.1111/acel.12733

By:

Rodriguez‐Garcia, Marta;
Fortier, Jared M.;
Barr, Fiona D.;
Wira, Charles R.

Publication type:

Article

Sex hormone modulation of human uterine epithelial cell immune responses.

Published in:

Integrative & Comparative Biology, 2006, v. 46, n. 6, p. 1082, doi. 10.1093/icb/icl036

By:

Fahey, John V.;
Schaefer, Todd N.;
Wira, Charles R.

Publication type:

Article

When to Stop CPR and When to Perform Rhythm Analysis.

Published in:

Journal of Intensive Care Medicine, 2016, v. 31, n. 8, p. 537, doi. 10.1177/0885066614561589

By:

Giberson, Brandon;
Uber, Amy;
F. Gaieski, David;
Miller, Joseph B.;
Wira, Charles;
Berg, Katherine;
Giberson, Tyler;
Cocchi, Michael N.;
S. Abella, Benjamin;
Donnino, Michael W.

Publication type:

Article

Effect of oestradiol on PAMP-mediated CCL20/MIP-3α production by mouse uterine epithelial cells in culture.

Published in:

Immunology, 2006, v. 118, n. 2, p. 185, doi. 10.1111/j.1365-2567.2006.02353.x

By:

Soboll, Gisela;
Crane-Godreau, Mardi A.;
Lyimo, Magdalena A.;
Wira, Charles R.

Publication type:

Article

Differential regulation of neutrophil chemotaxis to IL-8 and fMLP by GM-CSF: lack of direct effect of oestradiol.

Published in:

Immunology, 2006, v. 117, n. 2, p. 205, doi. 10.1111/j.1365-2567.2005.02280.x

By:

Li Shen;
Smith, Jennifer M.;
Zheng Shen;
Hussey, Stephen B.;
Wira, Charles R.;
Fanger, Michael W.

Publication type:

Article

Effect of oestradiol on mouse uterine epithelial cell tumour necrosis factor-α release is mediated through uterine stromal cells.

Published in:

Immunology, 2005, v. 115, n. 1, p. 99, doi. 10.1111/j.1365-2567.2005.02134.x

By:

Grant-Tschudy, Katherine S.;
Wira, Charles R.

Publication type:

Article

Chemokine receptor expression in the human ectocervix: implications for infection by the human immunodeficiency virus-type I.

Published in:

Immunology, 2004, v. 113, n. 4, p. 524, doi. 10.1111/j.1365-2567.2004.01990.x

By:

Yeaman, Grant R.;
Asin, Susana;
Weldon, Sally;
Demian, Douglas J.;
Collins, Jane E.;
Gonzalez, Jorge L.;
Wira, Charles R.;
Fanger, Michael W.;
Howell, Alexandra L.

Publication type:

Article

Toll-like receptor (TLR) expression and TLR-mediated cytokine/chemokine production by human uterine epithelial cells.

Published in:

Immunology, 2004, v. 112, n. 3, p. 428, doi. 10.1111/j.1365-2567.2004.01898.x

By:

Schaefer, Todd M.;
Desouza, Kristin;
Fahey, John V.;
Beagley, Kenneth W.;
Wira, Charles R.

Publication type:

Article

The innate immune system: gatekeeper to the female reproductive tract.

Published in:

2004

By:

Wira, Charles R.;
Fahey, John V.

Publication type:

Editorial

Oestradiol regulation of antigen presentation by uterine stromal cells: role of tranforming growth factor-β production by epithelial cells in mediating antigen-presenting cell function.

Published in:

Immunology, 2003, v. 109, n. 3, p. 398, doi. 10.1046/j.1365-2567.2003.01670.x

By:

Wira, Charles R.;
Rossoll, Richard M.

Publication type:

Article

Human immunodeficiency virus receptor and coreceptor expression on human uterine epithelial cells: regulation of expression during the menstrual cycle and implications for human immunodeficiency virus infection.

Published in:

Immunology, 2003, v. 109, n. 1, p. 137, doi. 10.1046/j.1365-2567.2003.01623.x

By:

Yeaman, Grant R.;
Howell, Alexandra L.;
Weldon, Sally;
Demian, Douglas J.;
Collins, Jane E.;
O'Connell, Denise M.;
Asin, Susana N.;
Wira, Charles R.;
Fanger, Michael W.

Publication type:

Article

Aging modifies endometrial dendritic cell function and unconventional double negative T cells in the human genital mucosa.

Published in:

Immunity & Ageing, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12979-023-00360-w

By:

Parthasarathy, Siddharth;
Shen, Zheng;
Carrillo-Salinas, Francisco J.;
Iyer, Vidya;
Vogell, Alison;
Illanes, Diego;
Wira, Charles R.;
Rodriguez-Garcia, Marta

Publication type:

Article

Etomidate use in severe sepsis and septic shock patients does not contribute to mortality.

Published in:

Internal & Emergency Medicine, 2011, v. 6, n. 3, p. 253, doi. 10.1007/s11739-011-0553-3

By:

Ehrman, Robert;
Wira, Charles;
Lomax, Afsaneh;
Hayward, Alison;
Marcelin, Jean;
Ellis, Thomas;
Przyklenk, Karin;
Volturo, Gregory;
Mullen, Marie

Publication type:

Article

Diffusion‐Weighted Imaging Fluid‐Attenuated Inversion Recovery Mismatch on Portable, Low‐Field Magnetic Resonance Imaging Among Acute Stroke Patients.

Published in:

Annals of Neurology, 2024, v. 96, n. 2, p. 321, doi. 10.1002/ana.26954

By:

Sorby‐Adams, Annabel;
Guo, Jennifer;
de Havenon, Adam;
Payabvash, Seyedmehdi;
Sze, Gordon;
Pinter, Nandor K.;
Jaikumar, Vinay;
Siddiqui, Adnan;
Baldassano, Steven;
Garcia‐Guarniz, Ana‐Lucia;
Zabinska, Julia;
Lalwani, Dheeraj;
Peasley, Emma;
Goldstein, Joshua N.;
Nelson, Olivia K.;
Schaefer, Pamela W.;
Wira, Charles R.;
Pitts, John;
Lee, Vivien;
Muir, Keith W.

Publication type:

Article