Works by Wipf, Peter

Results: 147

Lambert–Eaton myasthenic syndrome: mouse passive‐transfer model illuminates disease pathology and facilitates testing therapeutic leads.

Published in:

Annals of the New York Academy of Sciences, 2018, v. 1412, n. 1, p. 73, doi. 10.1111/nyas.13512

By:

Meriney, Stephen D.;
Tarr, Tyler B.;
Ojala, Kristine S.;
Wu, Man;
Li, Yizhi;
Lacomis, David;
Garcia‐Ocaña, Adolfo;
Liang, Mary;
Valdomir, Guillermo;
Wipf, Peter

Publication type:

Article

New calcium channel agonists as potential therapeutics in Lambert-Eaton myasthenic syndrome and other neuromuscular diseases.

Published in:

Annals of the New York Academy of Sciences, 2012, v. 1275, n. 1, p. 85, doi. 10.1111/nyas.12001

By:

Tarr, Tyler B.;
Valdomir, Guillermo;
Liang, Mary;
Wipf, Peter;
Meriney, Stephen D.

Publication type:

Article

Pericyclic Cascade Reactions of (Bicyclo[1.1.0]butylmethyl)aminesThis work was supported by the National Science Foundation (CHE-0315205). We thank Dr. Steve Geib for the X-ray crystallographic analysis and Juan Arredondo for help with the acquisition of the NMR spectra.

Published in:

Angewandte Chemie, 2006, v. 118, n. 25, p. 4278, doi. 10.1002/ange.200600723

By:

Peter Wipf;
Maciej A. A. Walczak

Publication type:

Article

Chiral ligand optimization in the asymmetric zirconium-zinc transmetalation aldehyde addition reaction.

Published in:

Chirality, 2008, v. 20, n. 3/4, p. 425, doi. 10.1002/chir.20468

By:

Wipf, Peter;
Jayasuriya, Nilukshi

Publication type:

Article

HPLC determinations of enantiomeric ratios.

Published in:

Chirality, 2007, v. 19, n. 1, p. 5

By:

Peter Wipf;
Stefan Werner;
Leslie A. Twining;
Christopher Kendall

Publication type:

Article

Assignment of the absolute configuration of [ n]-ladderanes by TD-DFT optical rotation calculations.

Published in:

Chirality, 2005, v. 17, n. 8, p. 507, doi. 10.1002/chir.20190

By:

Zuber, Gérard;
Goldsmith, Michael-Rock;
Beratan, David N.;
Wipf, Peter

Publication type:

Article

On the role of chiral catalysts in the alkenyl zirconocene/zinc addition to aldehydes: A study of ligand loading and asymmetric amplification.

Published in:

Chirality, 2003, v. 15, n. 3, p. 208, doi. 10.1002/chir.10176

By:

Wipf, Peter;
Jayasuriya, Nilukshi;
Ribe, Seth

Publication type:

Article

Synthetic and model computational studies of molar rotation additivity for interacting chiral centers: A reinvestigation of van't Hoff's principle.

Published in:

Chirality, 1997, v. 9, n. 5/6, p. 469, doi. 10.1002/(SICI)1520-636X(1997)9:5/6<469::AID-CHIR13>3.0.CO;2-M

By:

Kondru, Rama K.;
Lim, Sungtaek;
Wipf, Peter;
Beratan, David N.

Publication type:

Article

Transient Delivery of a KCNQ2/3-Specific Channel Activator 1 Week After Noise Trauma Mitigates Noise-Induced Tinnitus.

Published in:

JARO - Journal of the Association for Research in Otolaryngology, 2021, v. 22, n. 2, p. 127, doi. 10.1007/s10162-021-00786-3

By:

Marinos, Laura;
Kouvaros, Stylianos;
Bizup, Brandon;
Hambach, Bryce;
Wipf, Peter;
Tzounopoulos, Thanos

Publication type:

Article

Hydroxamic Acids as PARP‐1 Inhibitors: Molecular Design and Anticancer Activity of Novel Phenanthridinones.

Published in:

Helvetica Chimica Acta, 2023, v. 106, n. 10, p. 1, doi. 10.1002/hlca.202300133

By:

Bondar, Denys;
Bragina, Olga;
Lee, Ji Young;
Semenyuta, Ivan;
Järving, Ivar;
Brovarets, Volodymyr;
Wipf, Peter;
Bahar, Ivet;
Karpichev, Yevgen

Publication type:

Article

JP4-039 Mitigates Cisplatin-Induced Acute Kidney Injury by Inhibiting Oxidative Stress and Blocking Apoptosis and Ferroptosis in Mice.

Published in:

Antioxidants, 2024, v. 13, n. 12, p. 1534, doi. 10.3390/antiox13121534

By:

Airik, Merlin;
Clayton, Kacian;
Wipf, Peter;
Airik, Rannar

Publication type:

Article

Mitochondrial ROS Triggers KIN Pathogenesis in FAN1-Deficient Kidneys.

Published in:

Antioxidants, 2023, v. 12, n. 4, p. 900, doi. 10.3390/antiox12040900

By:

Airik, Merlin;
Arbore, Haley;
Childs, Elizabeth;
Huynh, Amy B.;
Phua, Yu Leng;
Chen, Chi Wei;
Aird, Katherine;
Bharathi, Sivakama;
Zhang, Bob;
Conlon, Peter;
Kmoch, Stanislav;
Kidd, Kendrah;
Bleyer, Anthony J.;
Vockley, Jerry;
Goetzman, Eric;
Wipf, Peter;
Airik, Rannar

Publication type:

Article

Special Issue: Flow Chemistry.

Published in:

2014

By:

Schuster, Elaine M.;
Wipf, Peter

Publication type:

Editorial

Photochemical Flow Reactions.

Published in:

Israel Journal of Chemistry, 2014, v. 54, n. 4, p. 361, doi. 10.1002/ijch.201400045

By:

Schuster, Elaine M.;
Wipf, Peter

Publication type:

Article

Biological studies of clavine alkaloids targeting CNS receptors.

Published in:

Frontiers in Psychiatry, 2023, p. 1, doi. 10.3389/fpsyt.2023.1286941

By:

Tasker, Nikhil R.;
Pazur, Ethan J.;
Wipf, Peter

Publication type:

Article

Linear and Nonlinear Support Vector Machine for the Classification of Human 5-HT<sub>1A</sub> Ligand Functionality.

Published in:

Molecular Informatics, 2012, v. 31, n. 1, p. 85, doi. 10.1002/minf.201100126

By:

Wang, Lirong;
Ma, Chao;
Wipf, Peter;
Xie, Xiang-Qun

Publication type:

Article

Memory of chirality in rebound cyclizations of α-amide radicals.

Published in:

Canadian Journal of Chemistry, 2013, v. 91, n. 1, p. 1, doi. 10.1139/v2012-085

By:

Sasmal, Aniruddha;
Taniguchi, Tsuyoshi;
Wipf, Peter;
Curran, Dennis P.

Publication type:

Article

Toward the total synthesis of lophotoxin — New methodologies and synthetic strategies.

Published in:

Canadian Journal of Chemistry, 2006, v. 84, n. 10, p. 1226, doi. 10.1139/V06-073

By:

Wipf, Peter;
Grenon, Michel

Publication type:

Article

Mitochondrial-derived reactive oxygen species (ROS) play a causal role in aging-related intervertebral disc degeneration.

Published in:

Journal of Orthopaedic Research, 2013, v. 31, n. 7, p. 1150, doi. 10.1002/jor.22320

By:

Nasto, Luigi A.;
Robinson, Andria R.;
Ngo, Kevin;
Clauson, Cheryl L.;
Dong, Qing;
St. Croix, Claudette;
Sowa, Gwendolyn;
Pola, Enrico;
Robbins, Paul D.;
Kang, James;
Niedernhofer, Laura J.;
Wipf, Peter;
Vo, Nam V.

Publication type:

Article

Deactivation of STAT3 and ERK and Activation of p38 in Ovarian Cancer Cells Treated with a Small Molecule Inhibitor of PTP4A3 Phosphatase.

Published in:

FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R2345

By:

Lazo, John S.;
Isbell, Kelly N.;
Rastelli, Ettore J.;
Wipf, Peter;
Sharlow, Elizabeth R.

Publication type:

Article

Endothelial Iron Homeostasis Regulates Blood-Brain Barrier Integrity via the HIF2α—Ve-Cadherin Pathway.

Published in:

Pharmaceutics, 2021, v. 13, n. 3, p. 311, doi. 10.3390/pharmaceutics13030311

By:

Rand, Daniel;
Ravid, Orly;
Atrakchi, Dana;
Israelov, Hila;
Bresler, Yael;
Shemesh, Chen;
Omesi, Liora;
Liraz-Zaltsman, Sigal;
Gosselet, Fabien;
Maskrey, Taber S.;
Schnaider Beeri, Michal;
Wipf, Peter;
Cooper, Itzik;
Neuhaus, Winfried

Publication type:

Article

Design, Synthesis, and Biological Evaluation of PKD Inhibitors.

Published in:

Pharmaceutics, 2011, v. 3, n. 2, p. 186, doi. 10.3390/pharmaceutics3020186

By:

George, Kara M.;
Frantz, Marie-Céline;
Bravo-Altamirano, Karla;
LaValle, Courtney R.;
Tandon, Manuj;
Leimgruber, Stephanie;
Sharlow, Elizabeth R.;
Lazo, John S.;
Wang, Q. Jane;
Wipf, Peter

Publication type:

Article

Deciphering of mitochondrial cardiolipin oxidative signaling in cerebral ischemia-reperfusion.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2015, v. 35, n. 2, p. 319, doi. 10.1038/jcbfm.2014.204

By:

Ji, Jing;
Baart, Sophie;
Vikulina, Anna S;
Clark, Robert SB;
Anthonymuthu, Tamil S;
Tyurin, Vladimir A;
Du, Lina;
St Croix, Claudette M;
Tyurina, Yulia Y;
Lewis, Jesse;
Skoda, Erin M;
Kline, Anthony E;
Kochanek, Patrick M;
Wipf, Peter;
Kagan, Valerian E;
Bayır, Hülya

Publication type:

Article

Regulation and targeting of androgen receptor nuclear localization in castration-resistant prostate cancer.

Published in:

2021

By:

Shidong Lv;
Qiong Song;
Guang Chen;
Erdong Cheng;
Wei Chen;
Cole, Ryan;
Zeyu Wu;
Pascal, Laura E.;
Ke Wang;
Wipf, Peter;
Nelson, Joel B.;
Qiang Wei;
Wenhua Huang;
Zhou Wang;
Lv, Shidong;
Song, Qiong;
Chen, Guang;
Cheng, Erdong;
Chen, Wei;
Wu, Zeyu

Publication type:

journal article

Exploring the Optical Activity Tensor by Anisotropic Rayleigh Optical Activity Scattering.

Published in:

ChemPhysChem, 2008, v. 9, n. 4, p. 504, doi. 10.1002/cphc.200890014

By:

Zuber, Gérard;
Wipf, Peter;
Beratan, David N.

Publication type:

Article

Exploring the Optical Activity Tensor by Anisotropic Rayleigh Optical Activity Scattering.

Published in:

ChemPhysChem, 2008, v. 9, n. 2, p. 265, doi. 10.1002/cphc.200700660

By:

Zuber, Gérard;
Wipf, Peter;
Beratan, David N.

Publication type:

Article

Solvent Effect on Optical Rotation: A Case Study of Methyloxirane in Water.

Published in:

ChemPhysChem, 2006, v. 7, n. 12, p. 2483, doi. 10.1002/cphc.200600477

By:

Mukhopadhyay, Parag;
Zuber, Gérard;
Goldsmith, Michael-Rock;
Wipf, Peter;
Beratan, David N.

Publication type:

Article

Towards Raman Optical Activity Calculations of Large Molecules.

Published in:

ChemPhysChem, 2005, v. 6, n. 4, p. 595, doi. 10.1002/cphc.200400544

By:

Grard Zuber;
Michael-Rock Goldsmith;
David N. Beratan;
Peter Wipf

Publication type:

Article

In vitro cytotoxicity, pharmacokinetics, tissue distribution, and metabolism of small-molecule protein kinase D inhibitors, kb-NB142-70 and kb-NB165-09, in mice bearing human cancer xenografts.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 2, p. 331, doi. 10.1007/s00280-012-2010-z

By:

Guo, Jianxia;
Clausen, Dana;
Beumer, Jan;
Parise, Robert;
Egorin, Merrill;
Bravo-Altamirano, Karla;
Wipf, Peter;
Sharlow, Elizabeth;
Wang, Qiming;
Eiseman, Julie

Publication type:

Article

Potentiation of neuromuscular transmission by a small molecule calcium channel gating modifier improves motor function in a severe spinal muscular atrophy mouse model.

Published in:

Human Molecular Genetics, 2023, v. 32, n. 11, p. 1901, doi. 10.1093/hmg/ddad019

By:

Ojala, Kristine S;
Kaufhold, Cassandra J;
Davey, Mykenzie R;
Yang, Donggyun;
Liang, Mary;
Wipf, Peter;
Badawi, Yomna;
Meriney, Stephen D

Publication type:

Article

Contribution of a Solute's Chiral Solvent Imprint to Optical Rotation.

Published in:

Angewandte Chemie International Edition, 2007, v. 46, n. 34, p. 6450, doi. 10.1002/anie.200702273

By:

Mukhopadhyay, Parag;
Zuber, Gérard;
Wipf, Peter;
Beratan, David N.

Publication type:

Article

JP4-039, a Mitochondria-Targeted Nitroxide, Mitigates the Effect of Apoptosis and Inflammatory Cell Migration in the Irradiated Mouse Retina.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6515, doi. 10.3390/ijms25126515

By:

Adeghate, Jennifer O.;
Epperly, Michael W.;
Davoli, Katherine Anne;
Lathrop, Kira L.;
Wipf, Peter;
Hou, Wen;
Fisher, Renee;
Thermozier, Stephanie;
Huq, M. Saiful;
Sahel, Jose-Alain;
Greenberger, Joel S.;
Eller, Andrew W.

Publication type:

Article

Concise total syntheses of lysergene, lysergine, isolysergine and festuclavine.

Published in:

ARKIVOC: Online Journal of Organic Chemistry, 2024, v. 2024, p. 1, doi. 10.24820/ark.5550190.p012.120

By:

Tasker, Nikhil R.;
Wipf, Peter

Publication type:

Article

Development and Implementation of a High-Throughput High-Content Screening Assay to Identify Inhibitors of Androgen Receptor Nuclear Localization in Castration-Resistant Prostate Cancer Cells.

Published in:

Assay & Drug Development Technologies, 2016, v. 14, n. 4, p. 226, doi. 10.1089/adt.2016.716

By:

Johnston, Paul A.;
Nguyen, Minh M.;
Dar, Javid A.;
Ai, Junkui;
Wang, Yujuan;
Masoodi, Khalid Z.;
Shun, Tongying;
Shinde, Sunita;
Camarco, Daniel P.;
Hua, Yun;
Huryn, Donna M.;
Wilson, Gabriela Mustata;
Lazo, John S.;
Nelson, Joel B.;
Wipf, Peter;
Wang, Zhou

Publication type:

Article

HCS Campaign to Identify Selective Inhibitors of IL-6-Induced STAT3 Pathway Activation in Head and Neck Cancer Cell Lines.

Published in:

Assay & Drug Development Technologies, 2015, v. 13, n. 7, p. 356, doi. 10.1089/adt.2015.663

By:

Johnston, Paul A.;
Sen, Malabika;
Hua, Yun;
Camarco, Daniel P.;
Shun, Tong Ying;
Lazo, John S.;
Wilson, Gabriela Mustata;
Resnick, Lynn O.;
LaPorte, Matthew G.;
Wipf, Peter;
Huryn, Donna M.;
Grandis, Jennifer R.

Publication type:

Article

A Bifunctional Dimethylsulfoxide Substitute Enhances the Aqueous Solubility of Small Organic Molecules.

Published in:

Assay & Drug Development Technologies, 2012, v. 10, n. 3, p. 269, doi. 10.1089/adt.2011.0421

By:

Sprachman, Melissa M.;
Wipf, Peter

Publication type:

Article

Profiling the NIH Small Molecule Repository for Compounds That Generate H2O2by Redox Cycling in Reducing Environments.

Published in:

Assay & Drug Development Technologies, 2010, v. 8, n. 2, p. 152, doi. 10.1089/adt.2009.0247

By:

Karina M. Soares;
Nicole Blackmon;
Tong Ying Shun;
Sunita N. Shinde;
Harold K. Takyi;
Peter Wipf;
John S. Lazo;
Paul A. Johnston

Publication type:

Article

Cdc25B Dual-Specificity Phosphatase Inhibitors Identified in a High-Throughput Screen of the NIH Compound Library.

Published in:

Assay & Drug Development Technologies, 2009, v. 7, n. 3, p. 250, doi. 10.1089/adt.2008.186

By:

Paul A. Johnston;
Caleb A. Foster;
Marni Brisson Tierno;
Tong Ying Shun;
Sunita N. Shinde;
William D. Paquette;
Kay M. Brummond;
Peter Wipf;
John S. Lazo

Publication type:

Article

Development of a 384-Well Colorimetric Assay to Quantify Hydrogen Peroxide Generated by the Redox Cycling of Compounds in the Presence of Reducing Agents.

Published in:

Assay & Drug Development Technologies, 2008, v. 6, n. 4, p. 505, doi. 10.1089/adt.2008.151

By:

Paul A. Johnston;
Karina M. Soares;
Sunita N. Shinde;
Caleb A. Foster;
Tong Ying Shun;
Harold K. Takyi;
Peter Wipf;
John S. Lazo

Publication type:

Article

Development and Implementation of a 384-Well Homogeneous Fluorescence Intensity High-Throughput Screening Assay to Identify Mitogen-Activated Protein Kinase Phosphatase-1 Dual-Specificity Protein Phosphatase Inhibitors.

Published in:

Assay & Drug Development Technologies, 2007, v. 5, n. 3, p. 319, doi. 10.1089/adt.2007.066

By:

Paul A. Johnston;
Caleb A. Foster;
Tong Ying Shun;
John J. Skoko;
Sunita Shinde;
Peter Wipf;
John S. Lazo

Publication type:

Article

Unique integrated stress response sensors regulate cancer cell susceptibility when Hsp70 activity is compromised.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.64977

By:

Sannino, Sara;
Yates, Megan E.;
Schurdak, Mark E.;
Oesterreich, Steffi;
Lee, Adrian V.;
Wipf, Peter;
Brodsky, Jeffrey L.

Publication type:

Article

How mono- and diphosphine ligands alter regioselectivity of the Rh-catalyzed annulative cleavage of bicyclo[1.1.0]butanes.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34837-x

By:

Chen, Pan-Pan;
Wipf, Peter;
Houk, K. N.

Publication type:

Article

TargetHunter: An In Silico Target Identification Tool for Predicting Therapeutic Potential of Small Organic Molecules Based on Chemogenomic Database.

Published in:

AAPS Journal, 2013, v. 15, n. 2, p. 395, doi. 10.1208/s12248-012-9449-z

By:

Lirong Wang;
Chao Ma;
Wipf, Peter;
Haibin Liu;
Weiwei Su;
Xiang-Qun Xie

Publication type:

Article

XJB-5-131-mediated improvement in physiology and behaviour of the R6/2 mouse model of Huntington's disease is age- and sex- dependent.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0194580

By:

Polyzos, Aris A.;
Wood, Nigel I.;
Williams, Paul;
Wipf, Peter;
Morton, A. Jennifer;
McMurray, Cynthia T.

Publication type:

Article

Evaluation of a Novel Calcium Channel Agonist for Therapeutic Potential in Lambert-Eaton Myasthenic Syndrome.

Published in:

Journal of Neuroscience, 2013, v. 33, n. 25, p. 10559, doi. 10.1523/JNEUROSCI.4629-12.2013

By:

Tarr, Tyler B.;
Malick, Waqas;
Liang, Mary;
Valdomir, Guillermo;
Frasso, Michael;
Lacomis, David;
Reddel, Stephen W.;
Garcia-Ocano, Adolfo;
Wipf, Peter;
Meriney, Stephen D.

Publication type:

Article

A novel androgen receptor antagonist JJ‐450 inhibits enzalutamide‐resistant mutant AR<sup>F876L</sup> nuclear import and function.

Published in:

Prostate, 2020, v. 80, n. 4, p. 319, doi. 10.1002/pros.23945

By:

Wu, Zeyu;
Wang, Ke;
Yang, Zhenyu;
Pascal, Laura E.;
Nelson, Joel B.;
Takubo, Keita;
Wipf, Peter;
Wang, Zhou

Publication type:

Article

Mitochondria as a Target in Treatment.

Published in:

Environmental & Molecular Mutagenesis, 2010, v. 51, n. 5, p. 462, doi. 10.1002/em.20554

By:

Frantz, Marie-Céline;
Wipf, Peter

Publication type:

Article

Synthesis and biological evaluation of a targeted library of protein phosphatase inhibitors.

Published in:

Biotechnology & Bioengineering, 2000, v. 71, n. 1, p. 58, doi. 10.1002/(SICI)1097-0290(200024)71:1<58::AID-BIT9>3.0.CO;2-0

By:

Wipf, Peter;
Aslan, Diana C.;
Luci, Diane K.;
Southwick, Eileen C.;
Lazo, John S.

Publication type:

Article

ETHE1 and MOCS1 deficiencies: Disruption of mitochondrial bioenergetics, dynamics, redox homeostasis and endoplasmic reticulum-mitochondria crosstalk in patient fibroblasts.

Published in:

Scientific Reports, 2019, v. 9, n. 1, p. N.PAG, doi. 10.1038/s41598-019-49014-2

By:

Grings, Mateus;
Seminotti, Bianca;
Karunanidhi, Anuradha;
Ghaloul-Gonzalez, Lina;
Mohsen, Al-Walid;
Wipf, Peter;
Palmfeldt, Johan;
Vockley, Jerry;
Leipnitz, Guilhian

Publication type:

Article

Lipidomics identifies cardiolipin oxidation as a mitochondrial target for redox therapy of brain injury.

Published in:

Nature Neuroscience, 2012, v. 15, n. 10, p. 1407, doi. 10.1038/nn.3195

By:

Ji, Jing;
Kline, Anthony E;
Amoscato, Andrew;
Samhan-Arias, Alejandro K;
Sparvero, Louis J;
Tyurin, Vladimir A;
Tyurina, Yulia Y;
Fink, Bruno;
Manole, Mioara D;
Puccio, Ava M;
Okonkwo, David O;
Cheng, Jeffrey P;
Alexander, Henry;
Clark, Robert S B;
Kochanek, Patrick M;
Wipf, Peter;
Kagan, Valerian E;
Bay?r, Hülya

Publication type:

Article